LOCUS       NM_001395159            9187 bp    mRNA    linear   PRI 12-JUN-2024
DEFINITION  Homo sapiens unc-79 homolog, NALCN channel complex subunit (UNC79),
            transcript variant 4, mRNA.
ACCESSION   NM_001395159 XM_011537021
VERSION     NM_001395159.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 9187)
  AUTHORS   Bayat,A., Liu,Z., Luo,S., Fenger,C.D., Hojte,A.F., Isidor,B.,
            Cogne,B., Larson,A., Zanus,C., Faletra,F., Keren,B., Musante,L.,
            Gourfinkel-An,I., Perrine,C., Demily,C., Lesca,G., Liao,W. and
            Ren,D.
  TITLE     A new neurodevelopmental disorder linked to heterozygous variants
            in UNC79
  JOURNAL   Genet Med 25 (9), 100894 (2023)
   PUBMED   37183800
  REMARK    GeneRIF: A new neurodevelopmental disorder linked to heterozygous
            variants in UNC79.
REFERENCE   2  (bases 1 to 9187)
  AUTHORS   Chua,H.C., Wulf,M., Weidling,C., Rasmussen,L.P. and Pless,S.A.
  TITLE     The NALCN channel complex is voltage sensitive and directly
            modulated by extracellular calcium
  JOURNAL   Sci Adv 6 (17), eaaz3154 (2020)
   PUBMED   32494638
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 9187)
  AUTHORS   Bramswig,N.C., Bertoli-Avella,A.M., Albrecht,B., Al Aqeel,A.I.,
            Alhashem,A., Al-Sannaa,N., Bah,M., Brohl,K., Depienne,C.,
            Dorison,N., Doummar,D., Ehmke,N., Elbendary,H.M., Gorokhova,S.,
            Heron,D., Horn,D., James,K., Keren,B., Kuechler,A., Ismail,S.,
            Issa,M.Y., Marey,I., Mayer,M., McEvoy-Venneri,J., Megarbane,A.,
            Mignot,C., Mohamed,S., Nava,C., Philip,N., Ravix,C., Rolfs,A.,
            Sadek,A.A., Segebrecht,L., Stanley,V., Trautman,C., Valence,S.,
            Villard,L., Wieland,T., Engels,H., Strom,T.M., Zaki,M.S.,
            Gleeson,J.G., Ludecke,H.J., Bauer,P. and Wieczorek,D.
  TITLE     Genetic variants in components of the NALCN-UNC80-UNC79 ion channel
            complex cause a broad clinical phenotype (NALCN channelopathies)
  JOURNAL   Hum Genet 137 (9), 753-768 (2018)
   PUBMED   30167850
  REMARK    GeneRIF: UNC79 variant is associated with neurodevelopmental
            diseases.
REFERENCE   4  (bases 1 to 9187)
  AUTHORS   Shamseldin,H.E., Faqeih,E., Alasmari,A., Zaki,M.S., Gleeson,J.G.
            and Alkuraya,F.S.
  TITLE     Mutations in UNC80, Encoding Part of the UNC79-UNC80-NALCN Channel
            Complex, Cause Autosomal-Recessive Severe Infantile Encephalopathy
  JOURNAL   Am J Hum Genet 98 (1), 210-215 (2016)
   PUBMED   26708753
  REMARK    GeneRIF: UNC80 encodes a large protein that is necessary for the
            stability and function of NALCN and for bridging NALCN to UNC79 to
            form a functional complex
REFERENCE   5  (bases 1 to 9187)
  AUTHORS   Lu,B., Zhang,Q., Wang,H., Wang,Y., Nakayama,M. and Ren,D.
  TITLE     Extracellular calcium controls background current and neuronal
            excitability via an UNC79-UNC80-NALCN cation channel complex
  JOURNAL   Neuron 68 (3), 488-499 (2010)
   PUBMED   21040849
REFERENCE   6  (bases 1 to 9187)
  AUTHORS   Speca,D.J., Chihara,D., Ashique,A.M., Bowers,M.S.,
            Pierce-Shimomura,J.T., Lee,J., Rabbee,N., Speed,T.P., Gularte,R.J.,
            Chitwood,J., Medrano,J.F., Liao,M., Sonner,J.M., Eger,E.I. 2nd,
            Peterson,A.S. and McIntire,S.L.
  TITLE     Conserved role of unc-79 in ethanol responses in lightweight mutant
            mice
  JOURNAL   PLoS Genet 6 (8), e1001057 (2010)
   PUBMED   20714347
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 9187)
  AUTHORS   Lind,P.A., Macgregor,S., Vink,J.M., Pergadia,M.L., Hansell,N.K., de
            Moor,M.H., Smit,A.B., Hottenga,J.J., Richter,M.M., Heath,A.C.,
            Martin,N.G., Willemsen,G., de Geus,E.J., Vogelzangs,N.,
            Penninx,B.W., Whitfield,J.B., Montgomery,G.W., Boomsma,D.I. and
            Madden,P.A.
  TITLE     A genomewide association study of nicotine and alcohol dependence
            in Australian and Dutch populations
  JOURNAL   Twin Res Hum Genet 13 (1), 10-29 (2010)
   PUBMED   20158304
  REMARK    GeneRIF: In the Australian GWAS, one SNP achieved genomewide
            significance for comorbid AD/ND, rs12882384 in KIAA1409 on
            chromosome 14 (p = 4.86 x 10(-8))).
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL122023.3, AL136338.4 and
            AL157858.5.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Jun 7, 2021 this sequence version replaced XM_011537021.2.
            
            Summary: The NALCN channel is responsible for Na(+) leak currents.
            The protein encoded by this gene, along with UNC80, is an accessory
            subunit of the NALCN channel that contributes to the Ca(2+)
            sensitivity of the channel. [provided by RefSeq, Sep 2016].
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA2145743,
                              SAMEA2157437 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000695012.1/ ENSP00000511643.1
            RefSeq Select criteria    :: based on manual assertion,
                                         conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-113               AL122023.3         154472-154584
            114-234             AL136338.4         120282-120402       c
            235-539             AL136338.4         113680-113984       c
            540-710             AL136338.4         110345-110515       c
            711-803             AL136338.4         100318-100410       c
            804-859             AL136338.4         91607-91662         c
            860-989             AL136338.4         90787-90916         c
            990-1054            AL136338.4         64031-64095         c
            1055-1143           AL136338.4         59427-59515         c
            1144-1184           AL136338.4         58747-58787         c
            1185-1213           AL136338.4         55495-55523         c
            1214-1443           AL136338.4         49855-50084         c
            1444-1615           AL136338.4         47242-47413         c
            1616-1846           AL136338.4         45377-45607         c
            1847-2037           AL136338.4         15989-16179         c
            2038-2161           AL136338.4         15257-15380         c
            2162-2302           AL136338.4         12875-13015         c
            2303-2524           AL136338.4         10010-10231         c
            2525-2752           AL136338.4         7697-7924           c
            2753-2894           AL136338.4         5729-5870           c
            2895-2974           AL136338.4         1398-1477           c
            2975-3123           AL136338.4         1165-1313           c
            3124-3281           AL157858.5         174229-174386       c
            3282-3463           AL157858.5         170526-170707       c
            3464-3665           AL157858.5         167296-167497       c
            3666-3845           AL157858.5         164648-164827       c
            3846-3911           AL157858.5         163105-163170       c
            3912-4198           AL157858.5         154983-155269       c
            4199-4381           AL157858.5         150762-150944       c
            4382-4544           AL157858.5         149712-149874       c
            4545-4694           AL157858.5         147025-147174       c
            4695-5915           AL157858.5         145225-146445       c
            5916-6023           AL157858.5         137158-137265       c
            6024-6140           AL157858.5         133429-133545       c
            6141-6224           AL157858.5         130767-130850       c
            6225-6327           AL157858.5         126819-126921       c
            6328-6468           AL157858.5         124369-124509       c
            6469-6507           AL157858.5         121420-121458       c
            6508-6620           AL157858.5         114212-114324       c
            6621-6706           AL157858.5         114041-114126       c
            6707-6880           AL157858.5         112659-112832       c
            6881-6949           AL157858.5         108805-108873       c
            6950-7060           AL157858.5         105352-105462       c
            7061-7165           AL157858.5         94611-94715         c
            7166-7243           AL157858.5         85372-85449         c
            7244-7333           AL157858.5         81405-81494         c
            7334-7509           AL157858.5         79226-79401         c
            7510-7696           AL157858.5         77763-77949         c
            7697-7894           AL157858.5         76120-76317         c
            7895-7972           AL157858.5         73654-73731         c
            7973-8014           AL157858.5         63400-63441         c
            8015-9187           AL157858.5         60190-61362         c
FEATURES             Location/Qualifiers
     source          1..9187
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q32.12"
     gene            1..9187
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /note="unc-79 homolog, NALCN channel complex subunit"
                     /db_xref="GeneID:57578"
                     /db_xref="HGNC:HGNC:19966"
                     /db_xref="MIM:616884"
     exon            1..113
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     CDS             92..8215
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /note="isoform 3 is encoded by transcript variant 4;
                     protein unc-79 homolog"
                     /codon_start=1
                     /product="protein unc-79 homolog isoform 3"
                     /protein_id="NP_001382088.1"
                     /db_xref="CCDS:CCDS91920.1"
                     /db_xref="GeneID:57578"
                     /db_xref="HGNC:HGNC:19966"
                     /db_xref="MIM:616884"
                     /translation="MSTKAEQFASKIRYLQEYHNRVLHNIYPVPSGTDIANTLKYFSQ
                     TLLSILSRTGKKENQDASNLTVPMTMCLFPVPFPLTPSLRPQVSSINPTVTRSLLYSV
                     LRDAPSERGPQSRDAQLSDYPSLDYQGLYVTLVTLLDLVPLLQHGQHDLGQSIFYTTT
                     CLLPFLNDDILSTLPYTMISTLATFPPFLHKDIIEYLSTSFLPMAILGSSRREGVPAH
                     VNLSASSMLMIAMQYTSNPVYHCQLLECLMKYKQEVWKDLLYVIAYGPSQVKPPAVQM
                     LFHYWPNLKPPGAISEYRGLQYTAWNPIHCQHIECHNAINKPAVKMCIDPSLSVALGD
                     KPPPLYLCEECSERIAGDHSEWLIDVLLPQAEISAICQKKNCSSHVRRAVVTCFSAGC
                     CGRHGNRPVRYCKRCHSNHHSNEVGAAAETHLYQTSPPPINTRECGAEELVCAVEAVI
                     SLLKEAEFHAEQREHELNRRRQLGLSSSHHSLDNADFDNKDDDKHDQRLLSQFGIWFL
                     VSLCTPSENTPTESLARLVAMVFQWFHSTAYMMDDEVGSLVEKLKPQFVTKWLKTVCD
                     VRFDVMVMCLLPKPMEFARVGGYWDKSCSTVTQLKEGLNRILCLIPYNVINQSVWECI
                     MPEWLEAIRTEVPDNQLKEFREVLSKMFDIELCPLPFSMEEMFGFISCRFTGYPSSVQ
                     EQALLWLHVLSELDIMVPLQLLISMFSDGVNSVKELANQRKSRVSELAGNLASRRVSV
                     ASDPGRRVQHNMLSPFHSPFQSPFRSPLRSPFRSPFKNFGHPGGRTIDFDCEDDEMNL
                     NCFILMFDLLLKQMELQDDGITMGLEHSLSKDIISIINNVFQAPWGGSHTCQKDEKAI
                     ECNLCQSSILCYQLACELLERLAPKEESRLVEPTDSLEDSLLSSRPEFIIGPEGEEEE
                     NPASKHGENPGNCTEPVEHAAVKNDTERKFCYQQLPVTLRLIYTIFQEMAKFEEPDIL
                     FNMLNCLKILCLHGECLYIARKDHPQFLAYIQDHMLIASLWRVVKSEFSQLSSLAVPL
                     LLHALSLPHGADIFWTIINGNFNSKDWKMRFEAVEKVAVICRFLDIHSVTKNHLLKYS
                     LAHAFCCFLTAVEDVNPAVATRAGLLLDTIKRPALQGLCLCLDFQFDTVVKDRPTILS
                     KLLLLHFLKQDIPALSWEFFVNRFETLSLEAQLHLDCNKEFPFPTTITAVRTNVANLS
                     DAALWKIKRARFARNRQKSVRSLRDSVKGPVESKRALSLPETLTSKIPMRLTRHEQSA
                     PALGGTPEQTPGQQSPENDNTIKDLLPEDAGIDHQTVHQLITVLMKFMAKDESSAESD
                     ISSAKAFNTVKRHLYVLLGYDQQEGCFMIAPQKMRLSTCFNAFIAGIAQVMDYNINLG
                     KHLLPLVVQVLKYCSCPQLRHYFQQPPRCSLWSLKPHIRQMWLKALLVILYKYPYRDC
                     DISKILLHLIHITVNTLNAQYHSCKPHATAGPLYSDNSNISRYSEKEKEEDSVFDESD
                     IHDTPTGPCNKESQTFFARLKRIGGSKMVKYQPVEMNVQRSEIELAEYRETGALQDSL
                     LHCVREESIPKKKLRSFKQKSLDIGNADSLLFTLDEHRRKSCIDRCDIEKPPTQAAYI
                     AQRPNDPGRSRQNSATRPDNSEIPENPAMEGFPDARRPVIPEVRLNCMETFEVKVDSP
                     VKPAPKEDLDLIDLSSDSTSGPEKHSILSTSDSDSLVFEPLPPLRIVESDEEEETMNQ
                     GDDGPSGKNAASSPSVPSHPSVLSLSTAPLVQVSVEDCSKDFSSKDSGNNQSAGNTDS
                     ALITLEDPMDAEGSSKPEELPEFSCGSPLTLKQKRDLLQKSFALPEMSLDDHPDPGTE
                     GEKPGELMPSSGAKTVLLKVPEDAENPTESEKPDTSAESDTEQNPERKVEEDGAEESE
                     FKIQIVPRQRKQRKIAVSAIQREYLDISFNILDKLGEQKDPDPSTKGLSTLEMPRESS
                     SAPTLDAGVPETSSHSSISTQYRQMKRGSLGVLTMSQLMKRQLEHQSSAPHNISNWDT
                     EQIQPGKRQCNVPTCLNPDLEGQPLRMRGATKSSLLSAPSIVSMFVPAPEEFTDEQPT
                     VMTDKCHDCGAILEEYDEETLGLAIVVLSTFIHLSPDLAAPLLLDIMQSVGRLASSTT
                     FSNQAESMMVPGNAAGVAKQFLRCIFHQLAPNGIFPQLFQSTIKDGTFLRTLASSLMD
                     FNELSSIAALSQLLEGLNNKKNLPAGGAMIRCLENIATFMEALPMDSPSSLWTTISNQ
                     FQTFFAKLPCVLPLKCSLDSSLRIMICLLKIPSTNATRSLLEPFSKLLSFVIQNAVFT
                     LAYLVELCGLCYRAFTKERDKFYLSRSVVLELLQALKLKSPLPDTNLLLLVQFICADA
                     GTKLAESTILSKQMIASVPGCGTAAMECVRQYINEVLDFMADMHTLTKLKSHMKTCSQ
                     PLHEDTFGGHLKVGLAQIAAMDISRGNHRDNKAVIRYLPWLYHPPSAMQQGPKEFIEC
                     VSHIRLLSWLLLGSLTHNAVCPNASSPCLPIPLDAGSHVADHLIVILIGFPEQSKTSV
                     LHMCSLFHAFIFAQLWTVYCEQSAVATNLQNQNEFSFTAILTALEFWSRVTPSILQLM
                     AHNKVMVEMVCLHVISLMEALQECNSTIFVKLIPMWLPMIQSNIKHLSAGLQLRLQAI
                     QNHVNHHSLRTLPGSGQSSAGLAALRKWLQCTQFKMAQVEIQSSEAASQFYPL"
     exon            114..234
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            235..539
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            540..710
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            711..803
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            804..859
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            860..989
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            990..1054
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            1055..1143
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            1144..1184
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            1185..1213
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            1214..1443
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            1444..1615
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            1616..1846
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            1847..2037
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            2038..2161
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            2162..2302
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            2303..2524
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            2525..2752
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            2753..2894
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            2895..2974
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            2975..3123
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            3124..3281
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            3282..3463
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            3464..3665
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            3666..3845
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            3846..3911
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            3912..4198
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            4199..4381
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            4382..4544
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            4545..4694
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            4695..5915
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            5916..6023
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            6024..6140
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            6141..6224
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            6225..6327
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            6328..6468
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            6469..6507
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            6508..6620
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            6621..6706
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            6707..6880
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            6881..6949
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            6950..7060
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            7061..7165
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            7166..7243
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            7244..7333
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            7334..7509
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            7510..7696
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            7697..7894
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            7895..7972
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            7973..8014
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     exon            8015..9187
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /inference="alignment:Splign:2.1.0"
     regulatory      8564..8569
                     /regulatory_class="polyA_signal_sequence"
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /note="hexamer: AATAAA"
     polyA_site      8583
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /note="major polyA site"
     regulatory      8625..8630
                     /regulatory_class="polyA_signal_sequence"
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /note="hexamer: AATAAA"
     polyA_site      8655
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
     regulatory      9168..9173
                     /regulatory_class="polyA_signal_sequence"
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
                     /note="hexamer: ATTAAA"
     polyA_site      9187
                     /gene="UNC79"
                     /gene_synonym="KIAA1409"
ORIGIN      
        1 atgcactctt ttcctcgcaa catcgctggc ggagcgaggg agctcacacg acacagattt
       61 tggggcaaag cctttccaac tggacagcac catgtccacc aaagcggagc agtttgcttc
      121 caagatccgg tacttgcagg aatatcataa ccgggttctc cacaacattt atcctgtacc
      181 atcaggaaca gatattgcaa acaccttgaa atacttttct cagaccttgt taagcatttt
      241 gtcccgcaca gggaagaagg aaaaccaaga tgcctccaat ttgacagtgc ccatgaccat
      301 gtgtcttttt cctgtgccat tcccactcac cccatctcta agaccgcagg tcagttccat
      361 caaccctact gttactcgct ccctccttta cagcgtcctg cgagatgctc cctcagaacg
      421 cggcccgcaa agtcgtgatg ctcagttgtc agactaccct tctttggact accaaggcct
      481 ctacgtgact ttggtgaccc tcctggatct agttccttta ctacagcacg gccaacacga
      541 tcttggacag tcgatatttt atacaactac atgtttgcta ccttttctca atgatgatat
      601 tctgagtact ttgccctaca cgatgatatc aacgttggct acctttcctc catttctgca
      661 caaggatatc attgaatatc ttagcacatc ttttctacca atggctatat tgggctcctc
      721 aaggagagaa ggtgtacctg cccatgttaa cctctctgca tcatccatgc taatgattgc
      781 aatgcagtac acatccaatc cagtgtatca ttgtcaatta ctggaatgcc tcatgaaata
      841 taaacaagaa gtctggaaag atcttttgta tgtgattgcg tatgggcctt cacaagtgaa
      901 gcctccagct gtgcaaatgc ttttccacta ctggcccaat ttaaaacctc ctggggcaat
      961 aagcgagtac agggggttgc agtacacagc ttggaatccc atccactgcc agcacattga
     1021 atgccacaat gcaattaaca aaccagctgt gaagatgtgt atagaccctt ccctgtcagt
     1081 agcgttgggt gataaaccac ccccgttgta tctctgtgaa gaatgcagcg agaggattgc
     1141 aggggaccac agtgagtggc tgattgatgt tcttctgcca caagctgaaa tatctgctat
     1201 atgtcagaaa aagaactgca gttcccacgt tagaagagca gttgtcacct gcttctcagc
     1261 agggtgctgt ggtcgtcacg gaaacaggcc tgttcggtac tgcaagaggt gccactcaaa
     1321 tcatcacagt aatgaagtgg gggccgctgc ggagactcac ctctatcaga cctctcctcc
     1381 gcccatcaac acgcgggaat gcggcgctga ggagctggtc tgcgccgtgg aagccgtgat
     1441 cagcttgttg aaagaagccg agttccatgc tgagcagcga gaacatgagc tgaaccggcg
     1501 gcggcagctg ggcctctcct cttcccacca ttccctggat aatgctgact ttgataacaa
     1561 ggacgatgat aaacacgatc agaggctgct cagtcaattc ggaatatggt tcttagtgag
     1621 cctctgcaca cccagtgaga acacgcctac agaaagcttg gcccggctgg tggccatggt
     1681 gtttcagtgg tttcactcca ctgcgtatat gatggatgat gaagtgggaa gtctggtgga
     1741 aaagctgaag cctcagtttg tcaccaaatg gctgaagacc gtatgtgatg ttcgcttcga
     1801 tgtcatggtc atgtgccttc ttcctaaacc catggaattt gccagggttg gtggctactg
     1861 ggataagtcc tgtagcacag tgactcagct gaaggaaggt ctcaaccgaa tcctctgcct
     1921 gatcccctat aatgtgatca atcaatctgt ctgggagtgt attatgccgg aatggctgga
     1981 agccatcaga acagaagtcc cagataatca gttaaaagaa ttcagggaag tattaagcaa
     2041 aatgtttgac attgaactct gtcctctgcc tttctcaatg gaggagatgt ttggttttat
     2101 tagttgtcgg tttacaggat acccctcctc tgtgcaggag caagctttac tgtggcttca
     2161 tgtattatcg gagttagata tcatggttcc acttcaacta ctaataagta tgttttctga
     2221 tggagttaat tcagtcaaag agctggcaaa tcaaagaaaa tcaagagtca gtgaactggc
     2281 agggaacctt gcatctcgaa gggtgagtgt tgcctctgat cctggccgac gagttcagca
     2341 caatatgctt agtccatttc atagtccttt ccagagtccg tttcggagtc ctttgcgtag
     2401 tccgtttcgt agccctttca agaattttgg acacccagga ggaaggacta ttgactttga
     2461 ttgtgaagat gatgaaatga atctaaattg tttcatcctc atgtttgatc ttctcctgaa
     2521 gcagatggag ttacaagatg atggaatcac gatgggttta gagcacagct tatcaaagga
     2581 cattatttct attataaaca atgtcttcca agccccctgg gggggatccc acacctgcca
     2641 gaaggacgaa aaagcaatcg agtgcaactt atgtcagtct agtatcctct gctatcagct
     2701 tgcttgtgaa ctcctggaga gactagctcc taaagaagaa agccggctgg tggagcccac
     2761 agacagcctg gaggatagcc tcctttcttc cagaccagag tttatcatag gccctgaagg
     2821 ggaggaggag gagaatcctg caagcaagca tggggagaac ccaggcaact gcaccgagcc
     2881 cgtggaacat gctgcagtaa agaatgatac cgaaagaaaa ttttgctacc aacagcttcc
     2941 ggtaacattg agactaatat ataccatttt ccaggaaatg gctaagtttg aagagccaga
     3001 cattcttttt aatatgctca attgcctgaa gattctctgt ctgcatggag aatgtttata
     3061 cattgccaga aaagatcacc ctcaattttt agcctacatt caggaccaca tgttgattgc
     3121 aagcctgtgg agggtcgtca aatccgagtt ctctcagctg tcttccctgg cagtccctct
     3181 tctcctccat gccctgtcac ttcctcatgg tgctgacatc ttctggacaa tcataaatgg
     3241 caatttcaac agcaaagact ggaagatgag gtttgaagca gtggaaaaag ttgctgtaat
     3301 ttgtagattt ctggatattc actcagtaac caaaaaccac ctgctgaagt actccctggc
     3361 acatgccttc tgctgcttcc tgacagcagt ggaggatgtc aaccccgcag tggctaccag
     3421 agctggtctc ctgcttgaca ccataaagag gccagcattg cagggtctat gtctttgtct
     3481 tgacttccag tttgatactg tggttaaaga cagacccaca attttgagca agcttttact
     3541 cttgcacttt cttaagcagg atattcctgc tctgagctgg gagttctttg tcaatagatt
     3601 tgagacgctt tctttggaag cccagctaca tttggattgt aacaaggaat ttccttttcc
     3661 tacaaccatc actgctgtga ggaccaatgt tgctaacctc agcgatgcag ccttatggaa
     3721 gatcaagaga gctcgctttg caagaaaccg ccagaagagt gtacgttccc tgagggacag
     3781 cgtgaaaggg cctgtggaat ccaagagggc gctctccctc cctgagaccc tgacctccaa
     3841 aattcctatg aggttgacca ggcatgagca gtctgctcca gctctcggtg ggacacccga
     3901 acagacgcca ggacaacaat ctcctgagaa tgacaacacc atcaaggacc tgctcccaga
     3961 agacgctggg atcgaccacc agacagttca ccagctgatt acagtgctca tgaagttcat
     4021 ggccaaggat gaaagcagcg ctgagtcaga catcagcagt gcaaaggcct tcaacacggt
     4081 caagcgacac ctgtacgtct tactcggcta tgaccagcag gaaggttgct tcatgattgc
     4141 acctcaaaaa atgcgcctgt caacttgctt taatgcattc attgcaggaa ttgcccaagt
     4201 tatggactat aacattaact tgggaaaaca ccttctcccc ttagtggttc aggtgctcaa
     4261 atactgctct tgtcctcaac tccggcatta tttccaacag ccgcctcgtt gctccctctg
     4321 gtccctaaag cctcacatcc ggcagatgtg gttgaaggcc ttgcttgtca tcctttacaa
     4381 gtatccatac cgagactgtg atatcagcaa gatcctgctg catctgattc acataacagt
     4441 caatacactc aatgcgcagt atcatagctg caagccccat gccacggcag gacctttgta
     4501 cagtgacaac agtaacataa gcagatacag cgaaaaagaa aaagaagaag atagtgtttt
     4561 tgatgaatct gatattcatg atacacctac tggaccctgc aataaagagt ctcaaacttt
     4621 ttttgcaaga ttgaaaagaa taggcggcag caaaatggtg aaatatcagc cggttgagat
     4681 gaatgttcag agaagtgaaa tagaactggc tgaatataga gagacgggtg cattacaaga
     4741 cagccttctc cactgtgtga gagaagaaag cattccgaaa aaaaagctac gctctttcaa
     4801 acaaaaatct cttgatatag ggaatgcaga ctcgcttttg tttacattag acgaacatcg
     4861 taggaagtcg tgcatagatc ggtgtgacat agagaagcct ccgacccaag ctgcgtatat
     4921 cgcacaaaga ccaaacgacc ctggacgttc tagacagaac tctgctacga ggcctgacaa
     4981 tagtgaaatc cccgagaacc cagctatgga agggtttcca gatgctcgaa ggcctgtcat
     5041 accagaggtt aggttaaact gtatggagac tttcgaggtg aaagttgact cgccggtaaa
     5101 gcctgctcct aaagaggatt tagatctgat agatctatcc tcagattcaa cctcggggcc
     5161 tgaaaaacac tctatactct caacctccga cagcgactct cttgtatttg agcctcttcc
     5221 ccctctcaga atagtcgaga gtgacgaaga agaggagacg atgaaccaag gcgatgacgg
     5281 cccctccggt aaaaatgctg cctcttctcc ctccgtcccc agccatccct ccgtcctcag
     5341 cctgagcaca gctccgcttg tacaagtaag tgtggaggat tgttccaaag acttttcttc
     5401 taaggactca ggaaataatc agtcagcagg gaacactgac tctgccctca tcactctgga
     5461 agaccctatg gacgccgaag gatcctcaaa gccagaggag ctgccagagt tctcctgcgg
     5521 tagcccactg acgctgaagc aaaaacgaga cctccttcag aagtcgtttg ctctccccga
     5581 gatgtcgctg gatgatcacc ctgacccggg cactgagggg gagaagcctg gggagctgat
     5641 gccaagttca ggggcaaaaa ccgtcctcct caaagttccc gaagatgcag agaaccccac
     5701 agaaagtgag aagcctgata ccagtgcaga atctgataca gaacagaatc ctgaaaggaa
     5761 ggtggaagag gatggagctg aggaatccga atttaagatt cagattgttc ccaggcagag
     5821 gaagcagagg aagattgctg tcagtgctat ccagagagag tacctcgaca tctccttcaa
     5881 cattctggac aaactgggag aacagaaaga tccagatcct tctactaaag gactttcaac
     5941 tttggaaatg ccacgagaat cttcatctgc ccctacgtta gatgcaggtg tgccggaaac
     6001 aagtagccat tcctcaatat caactcagta taggcagatg aaaaggggat ccctgggagt
     6061 tctgacaatg agccagttaa tgaagcggca gctggagcat cagtctagcg ccccccataa
     6121 catcagcaac tgggacactg aacagataca gcctgggaaa cgccagtgta acgtgccaac
     6181 gtgcctaaac cctgacctgg agggacagcc attgaggatg agaggtgcca ccaaatccag
     6241 cctgctatca gcaccaagca tagtcagtat gtttgtgcct gcacctgaag agttcactga
     6301 cgagcagccg acggtgatga cggacaaatg ccatgactgt ggggccattc ttgaagaata
     6361 cgatgaagag acacttgggc tagccatcgt ggtcctctcc acattcattc acttaagccc
     6421 agacctggca gccccgctgc tgctggatat catgcagtct gtgggaagat tggcatccag
     6481 tactaccttt tctaatcaag cagaaagcat gatggttccc ggcaatgcgg cgggggtggc
     6541 caagcagttc ctgcgctgca tcttccatca gttggccccc aacggcatct tcccgcagct
     6601 gttccaaagc acgatcaaag atgggacttt tttacggacc ttagcctcgt ctctgatgga
     6661 cttcaatgag ctgagctcca tcgcagctct cagtcagctc ctagagggtc taaataacaa
     6721 aaagaattta ccagcagggg gtgctatgat tcgctgtttg gaaaacattg caaccttcat
     6781 ggaagctttg cctatggatt ctcctagtag cctctggacc acaattagca accagtttca
     6841 gacatttttt gccaagctgc cttgtgtttt acctctgaag tgttctttag attccagttt
     6901 aagaattatg atttgcctct tgaagatccc ttctaccaat gctacaagga gtttgttgga
     6961 accattttca aaactgctca gctttgtaat tcagaatgcc gtcttcactc tggcctacct
     7021 ggtggagctg tgtggcttat gttaccgagc tttcactaag gaacgagata aattctactt
     7081 gtctcgtagt gttgttctag aacttctgca ggccctaaag ctcaaatctc ctttaccaga
     7141 tacaaacctt cttctgcttg ttcagtttat ttgtgcagat gctggaacca aactagctga
     7201 gtcaacaatc ctgagcaagc agatgatagc ctctgtacct ggatgtggga ctgcagcgat
     7261 ggagtgtgtg aggcagtaca tcaacgaagt gctggatttc atggcagaca tgcacacgct
     7321 gaccaaactg aagagccaca tgaagacatg ttcccagcct ctgcatgaag atacctttgg
     7381 gggacatctc aaagtggggc tggcccagat tgcagccatg gacatctcac ggggcaacca
     7441 cagagataac aaagctgtga tccgctatct gccttggctt tatcatcccc cctctgcaat
     7501 gcagcaagga cctaaagaat tcattgagtg tgtctcccat atccgactgt tgtcctggct
     7561 gctgctgggt tccctcactc acaatgcagt gtgcccaaat gcctcctctc cctgcctgcc
     7621 cattcctctg gatgcaggct cccacgttgc agaccatctt attgttatcc tgattggatt
     7681 tccagagcaa tcaaagacct ccgtgctgca catgtgctcc ctcttccacg cgttcatctt
     7741 tgctcagctg tggacagttt attgcgagca aagtgccgtc gctacaaatc tccaaaatca
     7801 gaatgaattc agcttcacgg cgatactgac agcactagaa ttttggagta gggtgacacc
     7861 cagcatcctt cagctaatgg cccataacaa agtgatggta gaaatggtgt gtctccatgt
     7921 gattagttta atggaggcat tgcaggaatg caattcgacc atttttgtca agctgatacc
     7981 tatgtggttg ccaatgattc agtcaaatat caagcactta tctgcgggac tccagcttcg
     8041 cctccaggct attcagaacc acgtgaacca ccacagccta aggacgctgc cgggctcggg
     8101 ccagagcagt gctggcctgg cagccctccg aaagtggttg cagtgcactc agttcaaaat
     8161 ggcccaggtg gagatccagt cctcggaagc agcctctcaa ttttatcctc tatgagtgga
     8221 ctcctcggcg ctcagtgtca acactctggt ttagcaataa tgggtttaaa aacaaacaat
     8281 ttgatccaag caggttgggg aacatattgg tactgtacat tctctttcta gtttagtaaa
     8341 agatgtgcaa aggccagaga gggccgaaaa tgaagctttc ttgctacaca tatttctgat
     8401 gactccttgg gctatctgat taagtgtttc cttacattat tttttaaaaa ccaaatcatt
     8461 tttctttaac taacttctat tttttttaag aaaaaaaaat agactggtgg gtactcacag
     8521 aaaagttgta taagtccccc tgttgctatt tttgatgata gagaataaat agggtttttg
     8581 aaacctttgt agtgtttttt cttaaaatcc actcttggca atgcaataaa aaaaaccgtc
     8641 accataagcc agtgacacct gactgaagct ttttgtcttt atcctgggaa aagtggcagc
     8701 ttgcaaggaa cattacaaag tgcacttaga aattaggtgg ttaaactgtg ccaattgttt
     8761 tcgttgtttt ataatatcat tttccaaaac tgtccagtaa gttttattat ttttaaaact
     8821 agtttttcaa ctcattagtt ctaggctgta ctctcttgta agctttatga taaccacttt
     8881 agttttgtga ataataaatt ttattctttt gttaatactt gtatacaatt taattgaaaa
     8941 ctgtagcttg cacactggac cagatgagtc cctcactggc acagtgccct gcacctggag
     9001 tgatgtttca taaaacggaa ttttaatagt gtaagagcac caagatttct ctgcacctat
     9061 acctagcgtt ggactgtgca ttccaaatga aattcctcct ctttatccct gtaatgcact
     9121 gactaacaga agacttacta cacatttaaa ctgtatattg acatgctatt aaatgcgttt
     9181 tttatta
//
