LOCUS       NM_001080534            8880 bp    mRNA    linear   PRI 07-APR-2024
DEFINITION  Homo sapiens unc-13 homolog C (UNC13C), transcript variant 1, mRNA.
ACCESSION   NM_001080534 XM_005254394 XM_930037
VERSION     NM_001080534.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 8880)
  AUTHORS   Kumar,V.B., Lee,C.H., Su,T.C., Lin,C.C., Mohammedsaleh,Z.M.,
            Yeh,C.M., Kiefer,R. and Lin,S.H.
  TITLE     Prognostic and Clinical Implications of UNC13C expression in
            Hepatocellular Carcinoma Patients
  JOURNAL   Int J Med Sci 20 (9), 1235-1239 (2023)
   PUBMED   37575271
  REMARK    GeneRIF: Prognostic and Clinical Implications of UNC13C expression
            in Hepatocellular Carcinoma Patients.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8880)
  AUTHORS   Dong,W., Zhao,L., Zhang,S., Zhang,S. and Si,H.
  TITLE     Circ-KIAA0907 inhibits the progression of oral squamous cell
            carcinoma by regulating the miR-96-5p/UNC13C axis
  JOURNAL   World J Surg Oncol 19 (1), 75 (2021)
   PUBMED   33715625
  REMARK    GeneRIF: Circ-KIAA0907 inhibits the progression of oral squamous
            cell carcinoma by regulating the miR-96-5p/UNC13C axis.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 8880)
  AUTHORS   Sudhof,T.C.
  TITLE     The synaptic vesicle cycle
  JOURNAL   Annu Rev Neurosci 27, 509-547 (2004)
   PUBMED   15217342
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC084759.2, AC010867.8, AC022302.7, AC034103.7 and AC068711.9.
            
            On or before Jun 16, 2020 this sequence version replaced
            XM_005254394.5, NM_001080534.2.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA2145743,
                              SAMEA2154665 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000260323.16/ ENSP00000260323.11
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-487               AC084759.2         154334-154820
            488-3726            AC010867.8         25721-28959
            3727-3749           AC010867.8         156091-156113
            3750-3814           AC010867.8         156693-156757
            3815-3893           AC022302.7         27216-27294
            3894-3899           AC022302.7         28616-28621
            3900-3971           AC022302.7         29805-29876
            3972-4191           AC022302.7         42411-42630
            4192-4419           AC022302.7         56354-56581
            4420-4561           AC022302.7         57541-57682
            4562-4731           AC022302.7         86081-86250
            4732-4847           AC022302.7         89997-90112
            4848-5011           AC022302.7         92396-92559
            5012-5168           AC022302.7         114125-114281
            5169-5237           AC022302.7         124229-124297
            5238-5327           AC022302.7         125953-126042
            5328-5456           AC022302.7         130547-130675
            5457-5590           AC034103.7         29278-29411
            5591-5676           AC034103.7         51212-51297
            5677-5803           AC034103.7         130838-130964
            5804-5900           AC034103.7         136309-136405
            5901-6044           AC034103.7         137065-137208
            6045-6122           AC034103.7         143347-143424
            6123-6200           AC034103.7         147983-148060
            6201-6289           AC034103.7         161779-161867
            6290-6439           AC068711.9         52809-52958
            6440-6563           AC068711.9         66614-66737
            6564-6620           AC068711.9         69527-69583
            6621-6701           AC068711.9         75324-75404
            6702-6849           AC068711.9         87692-87839
            6850-6942           AC068711.9         142219-142311
            6943-7102           AC068711.9         143687-143846
            7103-8880           AC068711.9         146720-148497
FEATURES             Location/Qualifiers
     source          1..8880
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="15"
                     /map="15q21.3"
     gene            1..8880
                     /gene="UNC13C"
                     /note="unc-13 homolog C"
                     /db_xref="GeneID:440279"
                     /db_xref="HGNC:HGNC:23149"
                     /db_xref="MIM:614568"
     exon            1..487
                     /gene="UNC13C"
                     /inference="alignment:Splign:2.1.0"
     exon            488..3726
                     /gene="UNC13C"
                     /inference="alignment:Splign:2.1.0"
     CDS             744..7388
                     /gene="UNC13C"
                     /note="isoform 1 is encoded by transcript variant 1;
                     Munc13-3; unc-13-like 3; protein unc-13 homolog C"
                     /codon_start=1
                     /product="protein unc-13 homolog C isoform 1"
                     /protein_id="NP_001074003.1"
                     /db_xref="CCDS:CCDS45264.1"
                     /db_xref="GeneID:440279"
                     /db_xref="HGNC:HGNC:23149"
                     /db_xref="MIM:614568"
                     /translation="MVANFFKSLILPYIHKLCKGMFTKKLGNTNKNKEYRQQKKDQDF
                     PTAGQTKSPKFSYTFKSTVKKIAKCSSTHNLSTEEDEASKEFSLSPTFSYRVAIANGL
                     QKNAKVTNSDNEDLLQELSSIESSYSESLNELRSSTENQAQSTHTMPVRRNRKSSSSL
                     APSEGSSDGERTLHGLKLGALRKLRKWKKSQECVSSDSELSTMKKSWGIRSKSLDRTV
                     RNPKTNALEPGFSSSGCISQTHDVMEMIFKELQGISQIETELSELRGHVNALKHSIDE
                     ISSSVEVVQSEIEQLRTGFVQSRRETRDIHDYIKHLGHMGSKASLRFLNVTEERFEYV
                     ESVVYQILIDKMGFSDAPNAIKIEFAQRIGHQRDCPNAKPRPILVYFETPQQRDSVLK
                     KSYKLKGTGIGISTDILTHDIRERKEKGIPSSQTYESMAIKLSTPEPKIKKNNWQSPD
                     DSDEDLESDLNRNSYAVLSKSELLTKGSTSKPSSKSHSARSKNKTANSSRISNKSDYD
                     KISSQLPESDILEKQTTTHYADATPLWHSQSDFFTAKLSRSESDFSKLCQSYSEDFSE
                     NQFFTRTNGSSLLSSSDRELWQRKQEGTATLYDSPKDQHLNGGVQGIQGQTETENTET
                     VDSGMSNGMVCASGDRSHYSDSQLSLHEDLSPWKEWNQGADLGLDSSTQEGFDYETNS
                     LFDQQLDVYNKDLEYLGKCHSDLQDDSESYDLTQDDNSSPCPGLDNEPQGQWVGQYDS
                     YQGANSNELYQNQNQLSMMYRSQSELQSDDSEDAPPKSWHSRLSIDLSDKTFSFPKFG
                     STLQRAKSALEVVWNKSTQSLSGYEDSGSSLMGRFRTLSQSTANESSTTLDSDVYTEP
                     YYYKAEDEEDYTEPVADNETDYVEVMEQVLAKLENRTSITETDEQMQAYDHLSYETPY
                     ETPQDEGYDGPADDMVSEEGLEPLNETSAEMEIREDENQNIPEQPVEITKPKRIRPSF
                     KEAALRAYKKQMAELEEKILAGDSSSVDEKARIVSGNDLDASKFSALQVCGGAGGGLY
                     GIDSMPDLRRKKTLPIVRDVAMTLAARKSGLSLAMVIRTSLNNEELKMHVFKKTLQAL
                     IYPMSSTIPHNFEVWTATTPTYCYECEGLLWGIARQGMKCLECGVKCHEKCQDLLNAD
                     CLQRAAEKSSKHGAEDKTQTIITAMKERMKIREKNRPEVFEVIQEMFQISKEDFVQFT
                     KAAKQSVLDGTSKWSAKITITVVSAQGLQAKDKTGSSDPYVTVQVGKNKRRTKTIFGN
                     LNPVWDEKFYFECHNSTDRIKVRVWDEDDDIKSRVKQHFKKESDDFLGQTIVEVRTLS
                     GEMDVWYNLEKRTDKSAVSGAIRLKINVEIKGEEKVAPYHIQYTCLHENLFHYLTEVK
                     SNGGVKIPEVKGDEAWKVFFDDASQEIVDEFAMRYGIESIYQAMTHFSCLSSKYMCPG
                     VPAVMSTLLANINAFYAHTTVSTNIQVSASDRFAATNFGREKFIKLLDQLHNSLRIDL
                     SKYRENFPASNTERLQDLKSTVDLLTSITFFRMKVLELQSPPKASMVVKDCVRACLDS
                     TYKYIFDNCHELYSQLTDPSKKQDIPREDQGPTTKNLDFWPQLITLMVTIIDEDKTAY
                     TPVLNQFPQELNMGKISAEIMWTLFALDMKYALEEHENQRLCKSTDYMNLHFKVKWFY
                     NEYVRELPAFKDAVPEYSLWFEPFVMQWLDENEDVSMEFLHGALGRDKKDGFQQTSEH
                     ALFSCSVVDVFAQLNQSFEIIKKLECPNPEALSHLMRRFAKTINKVLLQYAAIVSSDF
                     SSHCDKENVPCILMNNIQQLRVQLEKMFESMGGKELDSEASTILKELQVKLSGVLDEL
                     SVTYGESFQVIIEECIKQMSFELNQMRANGNTTSNKNSAAMDAEIVLRSLMDFLDKTL
                     SLSAKICEKTVLKRVLKELWKLVLNKIEKQIVLPPLTDQTGPQMIFIAAKDLGQLSKL
                     KEHMIREDARGLTPRQCAIMEVVLATIKQYFHAGGNGLKKNFLEKSPDLQSLRYALSL
                     YTQTTDALIKKFIDTQTSQSRSSKDAVGQISVHVDITATPGTGDHKVTVKVIAINDLN
                     WQTTAMFRPFVEVCILGPNLGDKKRKQGTKTKSNTWSPKYNETFQFILGKENRPGAYE
                     LHLSVKDYCFAREDRIIGMTVIQLQNIAEKGSYGAWYPLLKNISMDETGLTILRILSQ
                     RTSDDVAKEFVRLKSETRSTEESA"
     exon            3727..3749
                     /gene="UNC13C"
                     /inference="alignment:Splign:2.1.0"
     exon            3750..3814
                     /gene="UNC13C"
                     /inference="alignment:Splign:2.1.0"
     exon            3815..3893
                     /gene="UNC13C"
                     /inference="alignment:Splign:2.1.0"
     exon            3894..3899
                     /gene="UNC13C"
                     /inference="alignment:Splign:2.1.0"
     exon            3900..3971
                     /gene="UNC13C"
                     /inference="alignment:Splign:2.1.0"
     exon            3972..4191
                     /gene="UNC13C"
                     /inference="alignment:Splign:2.1.0"
     exon            4192..4419
                     /gene="UNC13C"
                     /inference="alignment:Splign:2.1.0"
     exon            4420..4561
                     /gene="UNC13C"
                     /inference="alignment:Splign:2.1.0"
     exon            4562..4731
                     /gene="UNC13C"
                     /inference="alignment:Splign:2.1.0"
     exon            4732..4847
                     /gene="UNC13C"
                     /inference="alignment:Splign:2.1.0"
     exon            4848..5011
                     /gene="UNC13C"
                     /inference="alignment:Splign:2.1.0"
     exon            5012..5168
                     /gene="UNC13C"
                     /inference="alignment:Splign:2.1.0"
     exon            5169..5237
                     /gene="UNC13C"
                     /inference="alignment:Splign:2.1.0"
     exon            5238..5327
                     /gene="UNC13C"
                     /inference="alignment:Splign:2.1.0"
     exon            5328..5456
                     /gene="UNC13C"
                     /inference="alignment:Splign:2.1.0"
     exon            5457..5590
                     /gene="UNC13C"
                     /inference="alignment:Splign:2.1.0"
     exon            5591..5676
                     /gene="UNC13C"
                     /inference="alignment:Splign:2.1.0"
     exon            5677..5803
                     /gene="UNC13C"
                     /inference="alignment:Splign:2.1.0"
     exon            5804..5900
                     /gene="UNC13C"
                     /inference="alignment:Splign:2.1.0"
     exon            5901..6044
                     /gene="UNC13C"
                     /inference="alignment:Splign:2.1.0"
     exon            6045..6122
                     /gene="UNC13C"
                     /inference="alignment:Splign:2.1.0"
     exon            6123..6200
                     /gene="UNC13C"
                     /inference="alignment:Splign:2.1.0"
     exon            6201..6289
                     /gene="UNC13C"
                     /inference="alignment:Splign:2.1.0"
     exon            6290..6439
                     /gene="UNC13C"
                     /inference="alignment:Splign:2.1.0"
     exon            6440..6563
                     /gene="UNC13C"
                     /inference="alignment:Splign:2.1.0"
     exon            6564..6620
                     /gene="UNC13C"
                     /inference="alignment:Splign:2.1.0"
     exon            6621..6701
                     /gene="UNC13C"
                     /inference="alignment:Splign:2.1.0"
     exon            6702..6849
                     /gene="UNC13C"
                     /inference="alignment:Splign:2.1.0"
     exon            6850..6942
                     /gene="UNC13C"
                     /inference="alignment:Splign:2.1.0"
     exon            6943..7102
                     /gene="UNC13C"
                     /inference="alignment:Splign:2.1.0"
     exon            7103..8880
                     /gene="UNC13C"
                     /inference="alignment:Splign:2.1.0"
     regulatory      8852..8857
                     /regulatory_class="polyA_signal_sequence"
                     /gene="UNC13C"
                     /note="hexamer: AATAAA"
     polyA_site      8880
                     /gene="UNC13C"
                     /note="major polyA site"
ORIGIN      
        1 agaaaagact cagccgcagc cggcgatgtg tgaagttccc agcacgcact cagcccggct
       61 gctcctcacc ctcaaatgtt gatgagcctg ggcgctcctc aacacacggg agagatccca
      121 ttttgctttc tgggagaaag agatgagaaa tgagccgcgg aaggtatttg gcaatgagaa
      181 gagtgaaagg cagtttcttg ccagcagcta agttgtagaa ttgcttcgga ggctacccgg
      241 gagtgcgata gaattgacaa gaaaagaaca gacaccgttg cagaccaagg catgcctgat
      301 tgcacgagtc ggatccctgg gacgcagctt ccactcctgt tctaactatt tgtgattgaa
      361 aaaaggaaac gagactagaa acacaattgc aagtggtgtt cctaaaagga aaacacatac
      421 actccaaaag gaggggaaga acaacccagt tggcgtgcac attttttttt aaaggagaat
      481 tcctcagaca ctacatggag ttatgtggaa atgagagaga ttcatgaaac ccctcctcca
      541 ggaaagaatg tctttcacag atggagcttt gcttctggtt tgcacaggac agcgacaatg
      601 tggcagagcc atgcctgccc ttcctgctct ttccagtgat tcacagaact tctgaacagt
      661 gatgcttgcc ttggattttc aggttttcat cctgatactt gtttactttt ctggggcaga
      721 aaagcttgca ctaattgctc tccatggtgg ctaatttttt caagagcttg attttacctt
      781 acattcataa gctttgcaaa ggaatgttta caaagaaatt gggaaataca aacaaaaaca
      841 aagagtatcg tcagcagaaa aaggatcaag acttccccac tgctggccag accaaatccc
      901 ccaaattttc ttacactttt aaaagcactg taaagaagat tgcaaagtgt tcatccactc
      961 acaacttatc cactgaggaa gacgaggcca gtaaagagtt ttccctctca ccaacattca
     1021 gttaccgagt agctattgcc aatggcctac aaaagaatgc taaagtaacc aacagtgata
     1081 atgaggatct gcttcaagag ctctcttcaa tcgagagttc ctactcagaa tcattaaatg
     1141 aactaaggag tagcacagaa aaccaggcac aatcaacaca cacaatgcca gttagacgca
     1201 acagaaagag ttcaagcagc cttgcaccct ctgagggcag ctctgacggg gagcgtactc
     1261 tacatggctt aaaactggga gctttacgaa aactgagaaa atggaaaaag agtcaagaat
     1321 gtgtctcctc agactcagag ttaagcacca tgaaaaaatc ctggggaata agaagtaagt
     1381 ctttggacag aactgtccga aacccaaaga caaatgccct ggagccaggg ttcagttcct
     1441 ctggctgcat tagccaaaca catgatgtca tggaaatgat ctttaaggaa cttcagggaa
     1501 taagtcagat tgaaacagaa ctttctgaac tacgagggca cgtcaatgct ctcaagcact
     1561 ccatcgatga gatctccagc agtgtggagg ttgtacaaag tgaaattgag cagttgcgca
     1621 cagggtttgt ccagtctcgg agggaaacta gagacatcca tgattatatt aagcacttag
     1681 gtcatatggg tagcaaggca agcctgagat ttttaaatgt gactgaagaa agatttgaat
     1741 atgttgaaag cgtggtgtac caaattctaa tagataaaat gggtttttca gatgcaccaa
     1801 atgctattaa aattgaattt gctcagagga taggacacca gagagactgc ccaaatgcaa
     1861 agcctcgacc catacttgtg tactttgaaa cccctcaaca aagggattct gtcttaaaaa
     1921 agtcatataa actcaaagga acaggcattg gaatctcaac agatattcta actcatgaca
     1981 tcagagaaag aaaagagaaa gggataccat cctcccagac atatgagagc atggctataa
     2041 agttgtctac tccagagcca aaaatcaaga agaacaattg gcagtcacct gatgacagtg
     2101 atgaagatct tgaatctgac ctcaatagaa acagttacgc tgtgctttcc aagtcagagc
     2161 ttctaacaaa gggaagtact tccaagccaa gctcaaaatc acacagtgct agatccaaga
     2221 ataaaactgc taatagcagc agaatttcaa ataaatcaga ttatgataaa atctcctcac
     2281 agttgccaga atcagatatc ttggaaaagc aaaccacaac ccattatgca gatgcaacac
     2341 ctctctggca ctcacagagt gattttttca ctgctaaact tagtcgttct gaatcagatt
     2401 tttccaaatt gtgtcagtct tactcagaag atttttcaga aaatcagttt ttcactagaa
     2461 ctaatggaag ctctctcctg tcatcttcgg accgggagct atggcagagg aaacaggaag
     2521 gaacagcgac cctgtatgac agtcccaagg accagcattt gaatggaggt gttcagggta
     2581 tccaagggca gactgaaact gaaaacacag aaactgtgga tagtggaatg agtaatggca
     2641 tggtgtgtgc atctggagac cggagtcatt acagtgattc tcagctctct ttacatgagg
     2701 atctttctcc atggaaggaa tggaatcaag gagctgattt aggcttggat tcatccaccc
     2761 aggaaggttt tgattatgaa acaaacagtc tttttgacca acagcttgat gtttacaata
     2821 aagacctaga atacttggga aagtgccaca gtgatcttca agatgactca gagagctacg
     2881 acttaactca agatgacaat tcttctccat gccctggctt ggataatgaa ccacaaggcc
     2941 agtgggttgg ccaatatgat tcttatcagg gagctaattc taatgagcta taccaaaatc
     3001 aaaaccagtt gtccatgatg tatcgaagtc aaagtgaatt gcaaagtgat gattcagagg
     3061 atgccccacc caaatcatgg catagtcgat taagcattga cctttctgat aagactttca
     3121 gcttcccaaa atttggatct acactgcaga gggctaaatc agccttggaa gtagtatgga
     3181 acaaaagcac acagagtctg agtgggtatg aggacagtgg ctcttcatta atggggagat
     3241 ttcggacatt atctcaatca actgcaaatg agtcaagtac cacacttgac tctgatgtct
     3301 acacggagcc ctattactat aaagcagagg atgaggaaga ttatactgaa ccagtggctg
     3361 acaatgaaac agattatgtt gaagtcatgg aacaagtcct tgctaaacta gaaaacagga
     3421 ctagtattac tgaaacagat gaacaaatgc aagcatatga tcacctttca tatgaaacac
     3481 cttatgaaac cccacaagat gagggttatg atggtccagc agatgatatg gttagtgaag
     3541 aggggttaga acccttaaat gaaacatcag ctgagatgga aataagagaa gatgaaaacc
     3601 aaaacattcc tgaacagcca gtggagatca caaagccaaa gagaattcgt ccttctttca
     3661 aagaagcagc tttaagggcc tataaaaagc aaatggcaga gttggaagag aagatcttgg
     3721 ctggagatag cagttctgtg gatgaaaagg ctcgaatagt aagtggcaat gatttggatg
     3781 cttccaaatt ttctgcactc caggtgtgtg gtggggctgg aggtggactt tatggtattg
     3841 acagcatgcc ggatcttcgc agaaaaaaaa ctttgcctat tgtccgagat gtggccatga
     3901 ccctggctgc ccggaaatct ggactctccc tggctatggt gattaggaca tccctaaata
     3961 atgaggaact gaaaatgcac gtcttcaaga agaccttgca ggcactgatc taccctatgt
     4021 cttctaccat cccacacaat tttgaggtct ggacggctac cacacccacc tactgttatg
     4081 agtgtgaagg gctcctgtgg ggcattgcaa ggcaaggcat gaagtgtctg gagtgtggag
     4141 tgaaatgcca cgaaaagtgt caggacctgc taaacgctga ctgcttgcag agagcagcag
     4201 aaaagagttc taaacatggt gccgaagaca agactcagac cattattaca gcaatgaaag
     4261 aaagaatgaa gatcagggag aaaaaccggc cagaagtatt tgaagtaatc caggaaatgt
     4321 ttcagatttc taaagaagat tttgtgcagt ttacaaaggc ggccaaacag agtgtactgg
     4381 atgggacatc taagtggtct gcaaaaataa ccattacagt ggtttctgca cagggtctac
     4441 aggcaaaaga taaaacaggg tctagtgatc catatgttac agttcaagtt ggaaagaaca
     4501 aaagaagaac aaaaaccatt tttggaaatt tgaatccagt atgggatgag aagttttatt
     4561 ttgagtgtca taactccaca gatcgaatca aagtcagagt atgggatgaa gatgatgata
     4621 ttaaatccag agtcaagcaa catttcaaaa aggagtcaga tgattttctg ggacaaacaa
     4681 ttgtagaagt gaggaccttg agtggagaaa tggatgtctg gtacaactta gagaaaagga
     4741 cagataagtc agctgtatct ggggccatac gattgaaaat caatgtggag ataaaaggag
     4801 aagagaaggt tgctccatat catattcaat atacatgttt acatgagaat ctgttccatt
     4861 acttgactga agtgaaatct aatggtggag tgaaaatccc agaagtcaaa ggggatgaag
     4921 cctggaaggt tttctttgat gatgcttccc aagaaatagt tgatgaattt gctatgcgtt
     4981 atggaattga atccatttat caagctatga cgcacttttc atgtctgtct tctaaataca
     5041 tgtgccccgg tgtccctgcc gtcatgagca ccttgctggc taatataaat gctttttatg
     5101 ctcacacaac agtttcaaca aacatacagg tttctgcctc agatcgattt gctgctacca
     5161 actttggtag ggaaaaattc ataaaactac tggaccagtt acataactct ttgaggattg
     5221 atctgtcaaa gtatagggaa aactttcctg caagcaatac tgaaagactg caagacctga
     5281 aatcaactgt tgacctgtta acaagtatca ccttttttag gatgaaggtt ctggagctgc
     5341 aaagcccccc aaaagcgagc atggtggtga aggactgtgt aagggcttgc ctggattcta
     5401 catacaagta tatttttgac aactgccatg aactctactc ccagctaaca gacccgagta
     5461 agaaacagga tattcctcgt gaagatcagg gaccaaccac caagaatttg gatttttggc
     5521 cccaacttat tacactgatg gttactatta ttgatgagga taaaactgcc tacacacctg
     5581 tcctgaatca gtttcctcaa gagctgaaca tgggaaaaat aagtgccgaa attatgtgga
     5641 ctctttttgc tctggatatg aaatatgcat tagaagaaca tgaaaatcag cggttatgca
     5701 agagcaccga ttatatgaat ttgcatttca aagttaaatg gttttataat gaatatgtgc
     5761 gtgaacttcc tgccttcaag gatgctgttc ctgaatactc cttgtggttt gaaccttttg
     5821 tcatgcaatg gctagatgaa aacgaagatg tgtcaatgga attccttcat ggagcactgg
     5881 gaagagacaa aaaagatgga ttccagcaga catctgagca tgctctcttt tcttgctccg
     5941 tggttgatgt ctttgctcag ctgaatcaga gctttgaaat tattaagaaa ctggaatgcc
     6001 ctaatcctga agcattatct cacttaatga gaagatttgc aaagactatc aataaagtgc
     6061 tgctccagta tgctgcaatt gtatcaagtg atttcagttc acattgtgat aaggaaaatg
     6121 tgccctgtat cttgatgaac aatattcaac aattgcgggt ccagctggaa aaaatgtttg
     6181 aatccatggg agggaaggag ctagattctg aagctagtac tattctaaaa gaacttcagg
     6241 ttaagctcag tggggtcctg gatgagctca gcgtcactta tggtgaaagt ttccaggtta
     6301 taattgaaga gtgtataaaa cagatgagtt tcgaactaaa tcaaatgaga gcaaatggaa
     6361 acaccacatc taataagaac agtgcagcaa tggatgcaga gattgtgtta agatctctta
     6421 tggatttttt ggacaaaaca ttaagtctct cagcaaaaat ctgtgagaaa acagtcctaa
     6481 agcgagtttt aaaagagtta tggaagctag ttctcaacaa aatagaaaaa caaattgttc
     6541 ttcctcctct gacagatcaa acaggacccc agatgatttt cattgcagct aaagatcttg
     6601 gacaattatc caaactgaag gagcacatga ttcgagagga tgccaggggt ctgacgccaa
     6661 gacaatgcgc tataatggag gtagtcctgg ctaccatcaa gcaatacttt catgcaggag
     6721 gaaatggcct gaaaaagaat ttcttggaga aaagcccaga tcttcagtct ctgagatatg
     6781 ctctcagtct ttatacccaa actactgatg ccttgataaa gaaattcata gatactcaaa
     6841 cctcacagag tcgttcctcc aaagatgccg tgggtcagat atctgttcat gtggacatca
     6901 ctgccacccc aggaacggga gatcataaag tcactgtaaa agtgattgct attaatgacc
     6961 taaactggca gaccacagca atgttccgcc cctttgtgga agtttgtata ctgggaccca
     7021 accttggaga caagaagaga aaacaaggca caaaaacaaa aagcaacaca tggtcaccaa
     7081 agtacaatga aacatttcag ttcattctcg gaaaggaaaa tcgaccaggg gcttatgaac
     7141 ttcatctctc agttaaggat tactgctttg ccagagaaga tcgaattatc ggaatgacag
     7201 tcattcagct acagaacata gcagaaaagg gaagctatgg ggcatggtat cctcttctga
     7261 aaaatatctc tatggatgaa actggtttga ctatccttag aatactctct cagaggacca
     7321 gtgatgatgt ggctaaagaa tttgtaagac ttaaatctga aacaagatct actgaagaga
     7381 gtgcttgaaa caaacactgc aagctaaata cataactata attgtttgac tactgcatgc
     7441 atgtgcaaat acatgggaat gtttagttca ctacatttca atgtttgcca gtactcatgt
     7501 acgatgtcta caaggtatgt aaaaaacctg ctgaactttt ataccaattc tggtctttgg
     7561 gaaatcagtg ttccatgaag tgccaaaatt atgatgtaaa gtgaaatatc aagaacacct
     7621 tttaacatgt ttattttgtt tctttaccca tttcacattc attaaacata atttttaaaa
     7681 actagtcttt tgagtttgcc catcagttgt ctttgttaaa tgagattata ttgcccatag
     7741 atcagaaaac atttattact caatttccat tttatttact tacctcatta tagatgtctt
     7801 acaaataccc ttttctacca taactagaaa tgcagtcact tctagaaagc atttgtaatt
     7861 ttatagtcgc agatattgtg atttttgcat acacattaaa atagaaaagg tgggaaatat
     7921 tttctgctga ccagtttcca acctttctga aatatcactg tgaagaaatg ctgttaaagc
     7981 aaacttacat aaagcaatgc tagagtttgt taacaatgtt tgatatatat tgacaaaact
     8041 ttgttctcta aaactgccaa gatcacatca catttgtaaa aatggtaagt taatgcattt
     8101 gtcatatagt gttatgtctt ggctttacca tatttcattc tttaaaaagt cattaatggt
     8161 ttagaaatgg gatggaaagt ttactgaaaa tacctgtaag taactatatt gttaatatct
     8221 tccctctgac agttatgact ctataatcag ttcaatgctt tatttttaaa aatattcaat
     8281 gattagtatt gaatgcagca ttactatata ttgtactgat gccaaaagtc atgttttcat
     8341 ccacttagtg aaaaaatagt aaaattaagt cggaagaaat tgcttaaaat tttgtaattt
     8401 gtatttataa gccccaaatg catcaaatgc agtaggagaa caatgtaata cagcttggta
     8461 cctaaaaata tagctaagtt ggtttttgaa tataaaacag tttatgaata tgtgcatttt
     8521 ctgtattgtt atgatttgac tttttagagt ctatgccaaa atatatggct gtaaaacagt
     8581 actttgtaat tataacttat ggtcataact gttagtggac tacttacaga agcagaaaca
     8641 agagcctgtt atgattgtgc tttgtgaaca agctgatcta atacgttaag tacagaagtg
     8701 cttagtatca tgactgtcag aaccattctg caactgagta tgaaatcaca gaccagtgag
     8761 gtgagctaat tcatgttaaa ctgttaggcc actgctttgt taatgactcc tctaaatgca
     8821 tagtgtgatg cgatcctctg gcatatgctt taataaatgg atgtatattg agcacatgca
//
