LOCUS       NM_001371189           14600 bp    mRNA    linear   PRI 13-FEB-2025
DEFINITION  Homo sapiens unc-13 homolog B (UNC13B), transcript variant 6, mRNA.
ACCESSION   NM_001371189
VERSION     NM_001371189.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 14600)
  AUTHORS   Grushin,K., Kalyana Sundaram,R.V., Sindelar,C.V. and Rothman,J.E.
  TITLE     Munc13 structural transitions and oligomers that may choreograph
            successive stages in vesicle priming for neurotransmitter release
  JOURNAL   Proc Natl Acad Sci U S A 119 (7) (2022)
   PUBMED   35135883
  REMARK    GeneRIF: Munc13 structural transitions and oligomers that may
            choreograph successive stages in vesicle priming for
            neurotransmitter release.
REFERENCE   2  (bases 1 to 14600)
  AUTHORS   Wang,J., Qiao,J.D., Liu,X.R., Liu,D.T., Chen,Y.H., Wu,Y., Sun,Y.,
            Yu,J., Ren,R.N., Mei,Z., Liu,Y.X., Shi,Y.W., Jiang,M., Lin,S.M.,
            He,N., Li,B., Bian,W.J., Li,B.M., Yi,Y.H., Su,T., Liu,H.K., Gu,W.Y.
            and Liao,W.P.
  TITLE     UNC13B variants associated with partial epilepsy with favourable
            outcome
  JOURNAL   Brain 144 (10), 3050-3060 (2021)
   PUBMED   33876820
  REMARK    GeneRIF: UNC13B variants associated with partial epilepsy with
            favourable outcome.
            Erratum:[Brain. 2022 Apr 18;145(2):e5. doi: 10.1093/brain/awab427..
            PMID: 34897376]
REFERENCE   3  (bases 1 to 14600)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   4  (bases 1 to 14600)
  AUTHORS   Xie,J., An,S.W., Jin,X., Gui,Y. and Huang,C.L.
  TITLE     Munc13 mediates klotho-inhibitable diacylglycerol-stimulated
            exocytotic insertion of pre-docked TRPC6 vesicles
  JOURNAL   PLoS One 15 (3), e0229799 (2020)
   PUBMED   32134975
  REMARK    GeneRIF: TRPC6 exocytosis by targeting to the C1 domain of
            Munc13-2.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 14600)
  AUTHORS   Wang,Y., Tan,J., Liu,D., Yang,Y. and Wu,H.
  TITLE     The Association of UNC13B Gene Polymorphisms and Diabetic Kidney
            Disease in a Chinese Han Population
  JOURNAL   Med Sci Monit 25, 8527-8533 (2019)
   PUBMED   31713534
  REMARK    GeneRIF: There were no significant differences in the distribution
            of allele or genotype frequencies in the five UNC13B SNP markers
            (rs13293564, rs17360668, rs10114937, rs661712, and rs2281999)
            between the Diabetic Kidney Disease group and control group of
            patients with type 2 diabetes mellitus .
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 14600)
  AUTHORS   Mochida,S., Orita,S., Sakaguchi,G., Sasaki,T. and Takai,Y.
  TITLE     Role of the Doc2 alpha-Munc13-1 interaction in the neurotransmitter
            release process
  JOURNAL   Proc Natl Acad Sci U S A 95 (19), 11418-11422 (1998)
   PUBMED   9736751
REFERENCE   7  (bases 1 to 14600)
  AUTHORS   Sakaguchi,G., Orita,S., Naito,A., Maeda,M., Igarashi,H., Sasaki,T.
            and Takai,Y.
  TITLE     A novel brain-specific isoform of beta spectrin: isolation and its
            interaction with Munc13
  JOURNAL   Biochem Biophys Res Commun 248 (3), 846-851 (1998)
   PUBMED   9704016
REFERENCE   8  (bases 1 to 14600)
  AUTHORS   Song,Y., Ailenberg,M. and Silverman,M.
  TITLE     Cloning of a novel gene in the human kidney homologous to rat
            munc13s: its potential role in diabetic nephropathy
  JOURNAL   Kidney Int 53 (6), 1689-1695 (1998)
   PUBMED   9607201
REFERENCE   9  (bases 1 to 14600)
  AUTHORS   Orita,S., Naito,A., Sakaguchi,G., Maeda,M., Igarashi,H., Sasaki,T.
            and Takai,Y.
  TITLE     Physical and functional interactions of Doc2 and Munc13 in
            Ca2+-dependent exocytotic machinery
  JOURNAL   J Biol Chem 272 (26), 16081-16084 (1997)
   PUBMED   9195900
REFERENCE   10 (bases 1 to 14600)
  AUTHORS   Betz,A., Okamoto,M., Benseler,F. and Brose,N.
  TITLE     Direct interaction of the rat unc-13 homologue Munc13-1 with the N
            terminus of syntaxin
  JOURNAL   J Biol Chem 272 (4), 2520-2526 (1997)
   PUBMED   8999968
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL353795.13, AL354669.12 and
            AL160274.9.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Oct 7, 2020 this sequence version replaced NM_001371189.1.
            
            Summary: This gene is expressed in the kidney cortical epithelial
            cells and is upregulated by hyperglycemia. The encoded protein
            shares a high level of similarity to the rat homolog, and contains
            3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia
            increases the levels of diacylglycerol, which has been shown to
            induce apoptosis in cells transfected with this gene and thus
            contribute to the renal cell complications of hyperglycemia.
            Studies in other species also indicate a role for this protein in
            the priming step of synaptic vesicle exocytosis. [provided by
            RefSeq, Jul 2008].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA2158800,
                              SAMN03465413 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000635942.2/ ENSP00000490228.1
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-297               AL353795.13        131726-132022
            298-327             AL354669.12        74539-74568
            328-427             AL354669.12        77644-77743
            428-545             AL354669.12        82993-83110
            546-669             AL354669.12        84227-84350
            670-743             AL354669.12        89815-89888
            744-801             AL354669.12        105517-105574
            802-1036            AL354669.12        142220-142454
            1037-9283           AL160274.9         6088-14334
            9284-9598           AL160274.9         16389-16703
            9599-9689           AL160274.9         19821-19911
            9690-9736           AL160274.9         72869-72915
            9737-9815           AL160274.9         76240-76318
            9816-9890           AL160274.9         81049-81123
            9891-10110          AL160274.9         81950-82169
            10111-10338         AL160274.9         83390-83617
            10339-10480         AL160274.9         84217-84358
            10481-10650         AL160274.9         86392-86561
            10651-10766         AL160274.9         87022-87137
            10767-10930         AL160274.9         87478-87641
            10931-11081         AL160274.9         88279-88429
            11082-11150         AL160274.9         90168-90236
            11151-11240         AL160274.9         91646-91735
            11241-11369         AL160274.9         92087-92215
            11370-11497         AL160274.9         95768-95895
            11498-11583         AL160274.9         96551-96636
            11584-11710         AL160274.9         102398-102524
            11711-11807         AL160274.9         102763-102859
            11808-11951         AL160274.9         103089-103232
            11952-12029         AL160274.9         103557-103634
            12030-12107         AL160274.9         104133-104210
            12108-12196         AL160274.9         104476-104564
            12197-12349         AL160274.9         104804-104956
            12350-12473         AL160274.9         105083-105206
            12474-12530         AL160274.9         105314-105370
            12531-12611         AL160274.9         105571-105651
            12612-12759         AL160274.9         106218-106365
            12760-12852         AL160274.9         109089-109181
            12853-13012         AL160274.9         109362-109521
            13013-14600         AL160274.9         109670-111257
FEATURES             Location/Qualifiers
     source          1..14600
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9p13.3"
     gene            1..14600
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /note="unc-13 homolog B"
                     /db_xref="GeneID:10497"
                     /db_xref="HGNC:HGNC:12566"
                     /db_xref="MIM:605836"
     exon            1..297
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /inference="alignment:Splign:2.1.0"
     CDS             276..13298
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /note="isoform 6 is encoded by transcript variant 6;
                     homolog of rat Munc13 (diacylglycerol-binding); protein
                     unc-13 homolog B; unc-13-like"
                     /codon_start=1
                     /product="protein unc-13 homolog B isoform 6"
                     /protein_id="NP_001358118.1"
                     /db_xref="CCDS:CCDS94404.1"
                     /db_xref="GeneID:10497"
                     /db_xref="HGNC:HGNC:12566"
                     /db_xref="MIM:605836"
                     /translation="MSLLCVRVKRAKFQGSPDKFNTYVTLKVQNVKSTTVAVRGDQPS
                     WEQDFMFEISRLDLGLSVEVWNKGLIWDTMVGTVWIALKTIRQSDEEGPGEWSTLEAE
                     TLMKDDEICGTRNPTPHKILLDTRFELPFDIPEEEARYWTYKWEQINALGADNEYSSQ
                     EESQRKPLPTAAAQCSFEDPDSAVDDRDSDYRSETSNSFPPPYHTASQPNASVHQFPV
                     PVRSPQQLLLQGSSRDSCNDSMQSYDLDYPERRAIRYAQKYDTLDRRRKKKSLYNHFE
                     DSERRQYGERSETKTNYKSTYSNTENCTLCHTEKKQNMGYPVLYPYKNGFVVKSGMQR
                     IKLESHDYDLSSCLRHCEKSSGSNQHVTNFTSLDILEDSTSSTSDELLGSPISDKQEN
                     LQSPTWHSSNVHHIGDFPEEYYVANSALPLQRMNCDAKTLGDLSECSIEEITPSSIEE
                     PKEDRIDTMDELQCLVETVSEYLAEKEEEINRFGSLSKTKKSHKQNSTLDAEQRTPGD
                     QIPPLTIVKNDKDTAISFPELTGVQCAVGSLFSSLTEKVGSGTKHLTNSVEKLVSLVP
                     EKTETLNQIEAINLGSKPRAMAVLGKDLSMQSPLSSQKDDNVNIDRHRKTSENEHMGN
                     KTGSLYFQNTTESIAKDLAPQSQSSVIKSVFSRLNPLKIFSEKEETKKDDDQSKPPRK
                     ESFVECGLELNKREGTLDNYSSSIIALNGSDEETTGWFQMPTSENLLSSQVTSEPSNL
                     VSSASKNDESLLEEKLCIDLSLLPDQQKICAKDTPGHPCIAGSRTANKEVFSKPLEED
                     KVTGNDDFLEPLRKSFSQFLLTSPETCSKESLSEPVKIRQVEEDGLERGSKKDGHSFS
                     FSGKLNLPFFRSLGHSEKQQELKEKGSIFPLFKFSFTDSKVTVNDQSLRGSAVTTDEE
                     SKKNCHEDTKHSSIKSSSVPNIHSDLGKFDSTEEFKKNDQINCPEDAKLNSIKSSSVP
                     NIHDDLEKFDSIKEFNKNDQVNCPEDAKLSSIKSGSAPNTQDNLGKFDSTEEFNQNDQ
                     INSPEDAKFNIIKSDSVTNINNDLGKFGNIEELNPSDHTAGQNFERDGLAIPGVVPKE
                     HITSDPLGEDKNLIQAASSVASDSSLECISTTSKSTLVNEINEDEVIDKTSKKNTQGS
                     FLSGLFNRFSSAENLSSQELNLKNDDSHHKNNTPGLISGIFNLLSNSGMIDHKPEEAK
                     FMSLGNMKSLNGDNHLSLDEVPATSCVTSENPKNHVEKHETSSFIEASLLPKENIPLS
                     DAGDDNHYCSPTEKNQQSEKHHPSSENIVLHCAPSAQLGFLEKSMAKRQMPNHVLEAK
                     LHENSNKLNSPVLNTNILNKSNNYQAFEEMNSPFCFEWDSDIKDLSKNSRKLQPVYYM
                     LNQNRFLSADACLWLDSENSVINFCQKDQNANILEWRTNPNSVIWCDLPYESFNQLAF
                     NEDYLLRGDVWAANSLYGNSGPLPINEANNSLEELPIDLSSSSDHEKTTCPVVDQESL
                     RMDENFVFSSFGYEYQEWLSCLEHGVWWPSEDGDYGYYMFHDGQYIYSLLTDSTGQYA
                     YLFIPDSYQEYLDCDLQTNGLSSITLDDSIISACSFKVLDKEDEIFWYVEEEPIDDPL
                     DLSLALPRSEEPLYLNLETFSQVLKESSCDQSDQPLDFSGYNRQKFKGDFRSFKERPC
                     GSEDAECTLDLRNQPQTISNHVSSRDQIIERDKNQPLAEDSSVHLSSFHWLQSSVEEV
                     TTLVHPENMTKGSQQAEETSLVNKVASVFSVLGASVGSTLKFDKSESLEALAMQKVNQ
                     QSDLAELTNDGFQSLIMSKQLEGNSPNVEKSLLKDSERQIVSNVQHPELIKNIRQEFS
                     LNKNNHVKKQSLLKSGFQVSQTTPQAKSGVKDDEIITTDSISVSPAPQHSGDERENYE
                     LPQGQSSKESDKTLFKSSLKLFSQEESSVSMTANEKQSSGFLNLFKTQVNKEGSPNLE
                     KIGDTNVKIPPQEKKESSGVSNFWGTLGDFFKANVSPIQTTENTSVSSMTIKDEVRSS
                     PTPMELASQGAGNFPAAPISSKGKARVRRLNKQTTIDDSRLEESTRGIQGNDLTEKEV
                     PFRDHLIQQSPNSSFSTSSLKESSRESSVETSGVTTVTEVSKSNEISFDTLSKRNSNE
                     QDHFSDKDWSFSMAATSSSQPELSTKKSIFSFLTGSEKSENRASATLPRAKSQAEGLF
                     TLPSFFSTASSSIKKDASHSSSTFSFFSLSFLDQKKETSGEKQSISTVVPVTSQPCKK
                     TNVFVESGSTMTRESSSGHRDSIAQEVVHEQQMAPCISINNTIEVTSLADELSVDKDC
                     QEKLSSNIVPGTSVDFQMNELQKDIIPPSPEFQAQAETFLTGPENLGIAPHEEEAFNH
                     KAFPSDSLSNSFSHAKQLIEKFNDLDTCTNCHQNEKFTTDPVNLPLEKAPDEVLPQIL
                     EPASSSPEPGCAGNLQNQDADKEEDKFALGSSVDMLSGFVTKVKSFSGSLIEPPKTLS
                     GLFSSPKSPKKNSFFSLASDVSSQPLKGELFGIFKSPKPEPYKQESSLPATSWLQNGC
                     SRDAVGSVPPERREAAFTALSSESTLSDCRMTVVSAKPESDILTDDPKLTTKMEDNNT
                     PENILEPQRSETINTSSFSGDDTGQGVLSLSDEGDMGILQATDTEASLEAENFALPAQ
                     LHPDPTCIAEELPPPIQPPLPLEPEPAIQTASTNQDLLELHPASSLETDTMLFNDASV
                     SQSTTLETEGHFSHPLLEDPVLAARESCEIIHAQKDPPVVPQETEQSRPRFEIPNVTT
                     WPKLRLPSSATNHGKPLSSFFSSPLPSGNRAAETGLMSSFKKLSTLFEGSSEGKGSVL
                     ASDSKLGFGKVDLSFPWPKENKGVPEQMPTESSPPVLVTSSDQDLNSSEANKALKSSQ
                     ISGASAQPGKVYTQPSGTSEQLVASPEVCAQGLSGSGEGGNQQEISASGEHWDTKANL
                     SSPACPSGKHEEEPSTVSEIFHQLEKQEEEAVPASTDSDLNVQQPVTLNDIKEPMTNK
                     SPTSSSRYGSSCNVSQGSSQLSELDQYHEQDDDHRETDSIHSCHSSHSLSRDGQAGFG
                     EQEKPLEVTGQAEKEAACEPKEMKEDATTHPPPDLVLQKDHFLGPQESFPEENASSPF
                     TQARAHWIRAVTKVRLQLQEIPDDGDPSLPQWLPEGPAGGLYGIDSMPDLRRKKPLPL
                     VSDLSLVQSRKAGITSAMATRTSLKDEELKSHVYKKTLQALIYPISCTTPHNFEVWTA
                     TTPTYCYECEGLLWGIARQGMRCSECGVKCHEKCQDLLNADCLQRAAEKSCKHGAEDR
                     TQNIIMAMKDRMKIRERNKPEIFEVIRDVFTVNKAAHVQQMKTVKQSVLDGTSKWSAK
                     ITITVVCAQGLQAKDKTGSSDPYVTVQVSKTKKRTKTIFGNLNPVWEEKFHFECHNSS
                     DRIKVRVWDEDDDIKSRVKQRLKRESDDFLGQTIIEVRTLSGEMDVWYNLEKRTDKSA
                     VSGAIRLQISVEIKGEEKVAPYHVQYTCLHENLFHYLTDIQGSGGVRIPEARGDDAWK
                     VYFDETAQEIVDEFAMRYGIESIYQAMTHFACLSSKYMCPGVPAVMSTLLANINAYYA
                     HTTASTNVSASDRFAASNFGKERFVKLLDQLHNSLRIDLSTYRNNFPAGSPERLQDLK
                     STVDLLTSITFFRMKVQELQSPPRASQVVKDCVKACLNSTYEYIFNNCHDLYSRQYQL
                     KQELPPEEQGPSIRNLDFWPKLITLIVSIIEEDKNSYTPVLNQFPQELNVGKVSAEVM
                     WHLFAQDMKYALEEHEKDHLCKSADYMNLHFKVKWLHNEYVRDLPVLQGQVPEYPAWF
                     EQFVLQWLDENEDVSLEFLRGALERDKKDGFQQTSEHALFSCSVVDVFTQLNQSFEII
                     RKLECPDPSILAHYMRRFAKTIGKVLMQYADILSKDFPAYCTKEKLPCILMNNVQQLR
                     VQLEKMFEAMGGKELDLEAADSLKELQVKLNTVLDELSMVFGNSFQVRIDECVRQMAD
                     ILGQVRGTGNASPDARASAAQDADSVLRPLMDFLDGNLTLFATVCEKTVLKRVLKELW
                     RVVMNTMERMIVLPPLTDQTGTQLIFTAAKELSHLSKLKDHMVREETRNLTPKQCAVL
                     DLALDTIKQYFHAGGNGLKKTFLEKSPDLQSLRYALSLYTQTTDTLIKTFVRSQTTQG
                     SGVDDPVGEVSIQVDLFTHPGTGEHKVTVKVVAANDLKWQTAGMFRPFVEVTMVGPHQ
                     SDKKRKFTTKSKSNNWAPKYNETFHFLLGNEEGPESYELQICVKDYCFAREDRVLGLA
                     VMPLRDVTAKGSCACWCPLGRKIHMDETGLTILRILSQRSNDEVAREFVKLKSESRST
                     EEGS"
     exon            298..327
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /inference="alignment:Splign:2.1.0"
     exon            328..427
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /inference="alignment:Splign:2.1.0"
     exon            428..545
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /inference="alignment:Splign:2.1.0"
     exon            546..669
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /inference="alignment:Splign:2.1.0"
     exon            670..743
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /inference="alignment:Splign:2.1.0"
     exon            744..801
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /inference="alignment:Splign:2.1.0"
     exon            802..1036
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /inference="alignment:Splign:2.1.0"
     exon            1037..9283
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /inference="alignment:Splign:2.1.0"
     exon            9284..9598
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /inference="alignment:Splign:2.1.0"
     exon            9599..9689
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /inference="alignment:Splign:2.1.0"
     exon            9690..9736
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /inference="alignment:Splign:2.1.0"
     exon            9737..9815
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /inference="alignment:Splign:2.1.0"
     exon            9816..9890
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /inference="alignment:Splign:2.1.0"
     exon            9891..10110
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /inference="alignment:Splign:2.1.0"
     exon            10111..10338
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /inference="alignment:Splign:2.1.0"
     exon            10339..10480
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /inference="alignment:Splign:2.1.0"
     exon            10481..10650
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /inference="alignment:Splign:2.1.0"
     exon            10651..10766
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /inference="alignment:Splign:2.1.0"
     exon            10767..10930
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /inference="alignment:Splign:2.1.0"
     exon            10931..11081
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /inference="alignment:Splign:2.1.0"
     exon            11082..11150
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /inference="alignment:Splign:2.1.0"
     exon            11151..11240
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /inference="alignment:Splign:2.1.0"
     exon            11241..11369
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /inference="alignment:Splign:2.1.0"
     exon            11370..11497
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /inference="alignment:Splign:2.1.0"
     exon            11498..11583
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /inference="alignment:Splign:2.1.0"
     exon            11584..11710
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /inference="alignment:Splign:2.1.0"
     exon            11711..11807
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /inference="alignment:Splign:2.1.0"
     exon            11808..11951
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /inference="alignment:Splign:2.1.0"
     exon            11952..12029
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /inference="alignment:Splign:2.1.0"
     exon            12030..12107
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /inference="alignment:Splign:2.1.0"
     exon            12108..12196
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /inference="alignment:Splign:2.1.0"
     exon            12197..12349
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /inference="alignment:Splign:2.1.0"
     exon            12350..12473
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /inference="alignment:Splign:2.1.0"
     exon            12474..12530
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /inference="alignment:Splign:2.1.0"
     exon            12531..12611
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /inference="alignment:Splign:2.1.0"
     exon            12612..12759
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /inference="alignment:Splign:2.1.0"
     exon            12760..12852
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /inference="alignment:Splign:2.1.0"
     exon            12853..13012
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /inference="alignment:Splign:2.1.0"
     exon            13013..14600
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      14582..14587
                     /regulatory_class="polyA_signal_sequence"
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /note="hexamer: AATAAA"
     polyA_site      14600
                     /gene="UNC13B"
                     /gene_synonym="MUNC13; munc13-2; UNC13; Unc13h2"
                     /note="major polyA site"
ORIGIN      
        1 agtcccggca gctcctacct cccagcgatg gcgtcgctgt gccgcgccca gtccccagcc
       61 tgccggccgg tactcaccgc tacccggagt tcgctcagac ggtgagattt ggggcgggtc
      121 cgaggcagcg gcgggacgct acctgcgacc gggaccatga ggagctgcca gacccgtggg
      181 gccggtaacg agagcagtcg cggcacctgc tgagaggaaa gagggagcgg tccggcgcgg
      241 ctggggcgcg gcagaggctt gcccgatcct cggccatgtc actgctctgc gtgcgcgtta
      301 aaagggccaa attccagggt tcaccagata aatttaacac atatgtgacc ctgaaagtac
      361 agaatgtgaa gagcacaact gtagcagttc gtggtgatca gccttcctgg gaacaggatt
      421 tcatgtttga gattagtcgc ctggacctgg gtctaagtgt ggaggtatgg aacaaaggac
      481 tgatctggga caccatggtg gggactgtgt ggattgcgct gaagactatt cgtcagtcgg
      541 atgaggaagg gcctggggaa tggtccacat tagaggcaga gacgttaatg aaagacgatg
      601 agatctgtgg aactagaaac ccaactcctc ataaaatttt gcttgataca agatttgagt
      661 tgccttttga tatcccagag gaggaagcca gatattggac ctacaaatgg gagcaaatca
      721 atgccttggg agctgacaat gagtattcta gtcaagaaga aagccagagg aagccattgc
      781 ccactgctgc cgcccagtgt tcttttgaag accctgatag tgccgtcgat gaccgagata
      841 gtgactatcg cagtgagacc agcaacagct tcccacctcc ttaccataca gcttcccagc
      901 ccaacgcttc tgtgcaccag ttccctgtgc cggtgcgatc gccacagcag ctgctacttc
      961 aaggcagttc ccgggactct tgtaatgact ctatgcaaag ttatgacctt gattatccag
     1021 agcggcgggc tatcaggtat gctcagaaat atgatacact agatagaaga agaaaaaaga
     1081 aatccttata caatcatttt gaagacagtg aaagaaggca atatggtgag agatctgaaa
     1141 ctaagactaa ctacaaaagt acatattcta atactgaaaa ttgtaccctt tgccatactg
     1201 aaaagaaaca aaatatgggg tacccagttt tgtaccccta caaaaatgga tttgtggtta
     1261 agagtggcat gcagcgcatt aagttggaaa gtcatgatta tgatctgtcc agttgtttaa
     1321 ggcactgtga aaagtcatct ggctcaaacc agcatgtcac taattttacc tcattagata
     1381 ttcttgaaga ttctactagt agtacttctg atgaacttct gggttccccc atttctgata
     1441 agcaggaaaa tttacagtca ccaacatggc attcatccaa tgtccaccat attggagatt
     1501 ttcctgagga atattatgta gcaaattcag cattgccatt acaaaggatg aattgtgatg
     1561 caaaaacact tggagatctg tctgagtgct ctatagaaga gataacccct tcctctattg
     1621 aggagcccaa ggaggaccgt attgatacaa tggatgagct tcagtgtttg gtagaaacgg
     1681 tgtcagaata tttagcagag aaggaagagg agattaatag atttggttca ctttcaaaaa
     1741 ctaaaaaatc acataaacaa aatagtactc ttgatgcaga acagagaacg cctggggatc
     1801 aaataccacc tttaactatt gtcaagaatg acaaggacac ggccatctct ttccctgagt
     1861 tgactggagt acaatgtgct gttggttctt tgtttagttc actcacagaa aaagtgggtt
     1921 caggcacaaa gcatctaaca aactctgtgg aaaagttggt ttccttagtt ccagaaaaaa
     1981 cagaaactct taatcaaata gaggcaatta atttgggatc taaacccaga gccatggcag
     2041 tattggggaa ggatctttcc atgcaatctc cattatcctc tcaaaaagat gataatgtga
     2101 atatagacag acatagaaaa acctctgaaa atgagcacat gggtaataaa actgggagtt
     2161 tatactttca gaatacaaca gaaagtattg caaaggactt ggctccacag agtcagagtt
     2221 cagttataaa gtcggttttc agcaggttaa atccattgaa gatcttttca gaaaaggagg
     2281 aaacaaaaaa agatgatgac cagagtaagc caccaagaaa agaaagcttt gttgagtgtg
     2341 gtttggagtt aaataaaagg gaaggcactc ttgacaatta cagtagtagc atcattgctt
     2401 taaatgggag tgatgaagaa actacgggct ggttccagat gcccacaagt gagaatttgt
     2461 tgtcctccca agtaaccagt gaaccttcaa acttagttag ttctgcaagt aaaaatgatg
     2521 agagtctatt ggaagaaaaa ctctgtatag atctgtctct tttaccagat caacaaaaaa
     2581 tatgtgccaa agatactcca ggacatcctt gtatagctgg cagtagaact gcaaataaag
     2641 aggtattttc aaagccatta gaggaggaca aagttacagg taatgatgat ttccttgagc
     2701 cactcagaaa atcatttagc cagtttttgc tcacttcccc tgagacttgt tcaaaggaaa
     2761 gtttgtcaga acctgtgaaa attcgccagg tggaggaaga tggtttagaa aggggctcta
     2821 agaaagatgg tcattccttt tcctttagtg gaaaactaaa tcttccattt tttagaagtc
     2881 ttggtcattc tgaaaagcaa caggagttaa aagagaaagg aagcattttt cctttgttta
     2941 aattttcttt cactgacagc aaggttactg ttaatgacca gagtttacgt ggctcagcag
     3001 taaccactga tgaggagagc aaaaaaaatt gccatgaaga taccaaacat agttcaataa
     3061 aatctagttc tgttccaaat attcatagtg atctaggaaa atttgacagt acagaggaat
     3121 ttaaaaagaa tgaccagata aattgtcctg aagatgccaa acttaattca ataaaatcta
     3181 gttcagttcc aaatattcat gatgatctag agaagtttga cagtataaag gaatttaata
     3241 agaatgacca agtaaattgt cctgaagatg ccaaacttag ttcaataaaa tctggttcag
     3301 ctccaaatac tcaggataat ctagggaaat ttgacagtac agaggaattt aatcagaatg
     3361 accaaataaa tagtcctgaa gatgccaaat ttaatataat aaagtctgat tcagttacaa
     3421 atattaataa tgatctgggg aaatttggga atatagagga attaaatcca agtgaccaca
     3481 cagcaggaca gaattttgaa agggatggct tagccatccc tggagttgtg cccaaagaac
     3541 atataacttc agatccttta ggagaagata agaatcttat acaagcagca tcttcagtag
     3601 catcagactc ttcattagag tgtatttcta ccacttccaa atccactttg gttaatgaaa
     3661 ttaatgaaga tgaggttata gataagactt ccaagaaaaa tacccaagga agcttccttt
     3721 ctggcctgtt taataggttt tcttctgctg aaaatttgtc tagtcaagaa ttaaatttga
     3781 aaaatgatga ctcccatcac aagaataata ccccaggttt aatctctgga atatttaacc
     3841 tgctatcaaa tagcggtatg attgatcata aaccagagga agcaaagttc atgtctttag
     3901 gcaacatgaa gagtttgaat ggagataacc atttatcctt ggatgaggtc cctgctactt
     3961 catgtgtgac ttctgagaac ccgaagaacc atgttgaaaa acatgaaact tctagcttca
     4021 tagaagcctc cttattacct aaagaaaaca taccattatc tgatgctggg gatgataatc
     4081 attattgttc ccctacagag aaaaaccagc aaagtgaaaa gcatcacccc tcctctgaga
     4141 acattgtact tcactgtgct ccaagtgctc agctaggttt tttggagaaa tctatggcta
     4201 agaggcaaat gccaaaccat gttcttgagg caaaactaca tgaaaattca aacaagttaa
     4261 attcacctgt actaaatacc aacattctca ataaatcaaa caactatcag gcttttgaag
     4321 agatgaacag tcctttctgt tttgaatggg actctgacat aaaagatttg tctaaaaatt
     4381 ccagaaaact tcagccagtt tattatatgt taaatcaaaa tagatttcta tcagccgatg
     4441 cttgcttgtg gcttgactca gaaaactcag tgataaattt ttgccaaaaa gatcaaaatg
     4501 caaacatctt ggagtggaga acaaatccaa acagtgtcat ttggtgtgac ttaccatatg
     4561 aatcattcaa tcagttagca tttaatgaag attacttatt aagaggtgat gtgtgggcag
     4621 ctaactcatt atatggaaac tctggtcctc ttccaattaa tgaggctaat aattcactag
     4681 aagaattacc cattgactta agttcttcat cagatcatga aaagactaca tgccccgtag
     4741 ttgatcaaga atcattaaga atggatgaaa actttgtttt ttcaagtttt ggttatgagt
     4801 accaggaatg gttgtcatgt cttgaacatg gagtgtggtg gccatcagag gatggggatt
     4861 atggatatta tatgtttcat gatggtcaat atatctattc tcttctcact gattctactg
     4921 ggcagtatgc atatttattt atacctgatt cttatcaaga gtatttggat tgtgatttac
     4981 agacaaatgg tctatcaagt attacgttgg atgacagcat tatttctgcc tgtagtttta
     5041 aagtacttga taaggaagat gaaatatttt ggtatgttga agaggaacca attgatgacc
     5101 ctcttgattt atctttagct ttgccaagaa gtgaggaacc attgtatcta aatttagaaa
     5161 ccttttcaca agtacttaaa gagtcaagtt gtgaccaaag cgatcagcca ctagattttt
     5221 caggctataa tcgtcaaaag tttaaaggag actttagatc tttcaaagaa aggccgtgtg
     5281 gttctgaaga cgctgaatgt acattagatc tcagaaatca gccccaaact attagtaatc
     5341 atgtctcaag cagagatcaa attatagaga gagataaaaa ccagcctcta gctgaagatt
     5401 catcagttca cctttccagt ttccattggc ttcagtcttc tgttgaagaa gttaccactt
     5461 tggttcatcc tgaaaatatg actaaaggct cacaacaagc agaagagaca tcattagtga
     5521 acaaagtggc ttcagtattt tctgttttgg gtgcctcagt tggtagtact ttgaagtttg
     5581 ataagagtga atccttagag gctttggcca tgcagaaagt gaatcagcag tcagatttag
     5641 cagagctcac aaatgatggc tttcagtcat taatcatgag taagcaatta gagggtaact
     5701 ccccaaatgt ggaaaaaagt cttcttaagg attcagaaag acagatagta tccaatgttc
     5761 agcatccaga attgatcaaa aatataaggc aagaattctc tttaaataaa aacaaccatg
     5821 tgaaaaagca aagtttgtta aaatctggtt tccaggtaag ccaaacaact cctcaggcta
     5881 aatcaggtgt aaaagatgat gaaatcatta caacagactc tatttcagtt tctcctgcac
     5941 ctcagcatag tggggatgag cgtgagaatt atgagcttcc ccagggccag tcatccaaag
     6001 agtctgataa aacattattt aaaagttcat tgaaactctt cagtcaagaa gaatcgtcag
     6061 ttagtatgac agcaaatgaa aaacagtcat ctggattttt gaatcttttt aagactcagg
     6121 tgaataaaga aggatcacca aacttagaaa agattggtga tacaaatgtc aagataccac
     6181 ctcaagaaaa gaaagaatct tctggtgttt caaatttttg gggtaccctt ggggatttct
     6241 ttaaagccaa tgtatctcct atacagacaa ctgaaaatac gtctgtttct tcaatgacta
     6301 ttaaggatga ggtcaggtca agtcctactc ctatggagct agctagccag ggtgctggga
     6361 actttcctgc tgcaccaatt tcctctaaag ggaaggctag agttagaaga ctgaacaaac
     6421 agactactat cgatgacagt aggttagagg aatcaactag agggatccag ggtaatgatt
     6481 tgactgaaaa agaggtacca ttcagagacc atctaatcca gcagtcacct aattcatctt
     6541 tttcaacaag tagtctcaaa gagtcttcca gggagtcttc agtagaaact agtggtgtga
     6601 ctacagtgac agaagtttca aaaagtaatg aaatatcctt tgataccctg agcaagagaa
     6661 attcaaatga acaagatcat ttttctgaca aagactggag tttctctatg gctgcaacat
     6721 cttcatctca accagagtta tcaaccaaaa agagtatatt ttcttttctc actggatctg
     6781 aaaaatctga gaacagagcc tctgctactc taccaagagc caaatctcag gcagaagggc
     6841 tattcacact tccttcattt ttttccactg ctagctcaag cattaagaag gatgcctctc
     6901 atagtagttc tacttttagt ttcttcagct tgtccttttt ggatcaaaaa aaggagacct
     6961 ctggggaaaa acaaagcatt tcaactgttg ttccagtgac ctcccagccc tgtaagaaga
     7021 caaatgtttt tgtagagagt ggtagcacaa tgaccagaga aagttccagt ggtcatagag
     7081 atagcatagc ccaagaagta gttcatgaac agcaaatggc accttgtatt tccattaaca
     7141 acaccattga ggttacctcc cttgcagatg agctcagtgt agacaaggac tgtcaggaaa
     7201 aactgagttc caatattgta ccagggacat cagtggattt ccagatgaat gaattgcaaa
     7261 aagacattat tcctccttca ccagaatttc aggcacaggc tgaaacattc ctcactggcc
     7321 cagagaacct tgggatagct ccccatgaag aagaggcttt caaccacaaa gccttcccca
     7381 gtgactcact gtccaactct ttttcacatg ctaaacagtt aattgaaaaa ttcaatgatt
     7441 tagacacttg tactaactgc caccaaaatg agaaatttac tactgaccca gtgaacttgc
     7501 cattagaaaa ggcccccgat gaggtcttac cacagatcct agagccagcc tcttcctctc
     7561 cagagccagg gtgtgcaggg aaccttcaga accaagatgc agataaagag gaagacaaat
     7621 ttgcattagg ctcttcagta gacatgcttt cagggtttgt gaccaaagtg aaatctttct
     7681 ctgggagctt aattgaacct cccaaaacac tctctggact tttctcctct cctaaatctc
     7741 caaagaaaaa ctcctttttc tctcttgctt ctgatgtatc atctcagccc ctcaaaggtg
     7801 aattatttgg aattttcaaa agtcccaagc cagagccata caaacaagaa tcatctctcc
     7861 cagctacttc atggcttcaa aatggttgtt ccagagatgc tgtaggatca gtacctccag
     7921 aaaggagaga agctgccttt acagcactaa gttcagaatc tactctcagt gactgtagaa
     7981 tgactgtggt tagtgcaaag ccagaatcag atatcttgac agatgatcct aaactaacaa
     8041 ccaaaatgga agacaataat actcctgaaa atattctgga acctcaacgt tctgaaacaa
     8101 ttaatacatc ttctttctcg ggtgatgata ctgggcaagg agtattgtct ctgagtgatg
     8161 aaggagacat ggggatattg caagctacag acacggaggc atcgttagaa gcagagaact
     8221 ttgcgctgcc agcacagttg catccagatc ctacctgcat tgccgaagag cttcctcctc
     8281 ccattcagcc acctcttcct cttgagccag agccagctat tcaaactgcc tccacaaacc
     8341 aagacttact ggagctgcat ccagccagtt cactagaaac tgatactatg ctgttcaatg
     8401 atgcaagtgt gagccagagc accactctgg aaaccgaagg gcacttttct catcctctgc
     8461 tggaggaccc tgtgcttgct gccagagaaa gttgtgagat aattcatgcc cagaaagatc
     8521 cacctgtagt accccaggaa acagagcagt caagaccacg ttttgagatc ccaaatgtga
     8581 ccacttggcc aaagcttcgt ttgccatcct ctgctactaa ccatgggaaa ccactgagct
     8641 ctttcttttc ctcacctctc ccctctggca atagagcagc agagactggt ttaatgtcca
     8701 gttttaagaa gttgtcaact ctatttgagg gaagtagtga ggggaaaggg agtgtattag
     8761 caagtgattc aaaactagga tttggaaagg tagatctttc atttccatgg ccaaaagaga
     8821 acaaaggggt ccctgaacaa atgcctacag aatcctcccc tccagtttta gttactagca
     8881 gtgatcagga ccttaactcc agtgaggcta acaaagcttt gaagtcttct caaatatctg
     8941 gggccagtgc tcagccaggt aaagtctaca ctcagccctc tgggacctct gagcagctgg
     9001 tggccagtcc agaggtctgt gctcaggggc tttcagggtc tggagaaggg ggaaaccagc
     9061 aggaaatctc agcatctgga gaacactggg ataccaaagc caacctgtct agccccgcct
     9121 gtccttcagg gaaacatgag gaagaaccct ccactgtctc tgagatattt caccagctag
     9181 aaaaacaaga agaggaggca gtacctgcca gtactgactc tgatttgaat gtacagcagc
     9241 cagtcactct gaatgacatc aaggagccca tgaccaacaa aagccccacc agcagcagta
     9301 ggtatggctc ctcctgtaat gtgagtcaag gaagctctca gctaagtgaa ctagaccagt
     9361 atcacgaaca agatgacgac catcgggaga cggactcgat tcattcttgc cacagctctc
     9421 acagcctgtc cagagatggc caagcaggtt ttggagaaca agagaaaccc ttggaggtga
     9481 caggtcaagc agagaaggag gcagcatgtg aacccaagga gatgaaagaa gatgccacaa
     9541 cccaccctcc cccagatctg gtgctgcaaa aagaccactt cctaggtccc caggagagtt
     9601 ttcctgagga gaatgcatct tcaccattta cccaagccag agcacattgg atccgagcag
     9661 ttaccaaggt tcgactccag ctgcaggaga ttccagatga tggtgacccc tctctgcctc
     9721 agtggctccc ggaagggcca gccggagggc tctatggcat tgacagcatg ccagatttac
     9781 gcagaaagaa gccactgcca cttgtcagtg atctgtcact ggtccagtct cggaaggcag
     9841 gaatcacttc tgcaatggct acacgcactt ctcttaagga cgaagagctg aaatcccacg
     9901 tgtataagaa aaccctgcag gccttaatct accccatttc gtgcaccact cctcataact
     9961 ttgaggtctg gacggccact accccaacct actgctatga gtgtgaaggc ctgctctggg
    10021 gcattgcccg gcagggcatg cgctgcagcg aatgtggagt caagtgccat gagaagtgcc
    10081 aggatctgct caatgctgac tgcctgcagc gggctgcaga aaagagctgt aaacatggag
    10141 ctgaggaccg gacccagaac attatcatgg ccatgaagga ccgcatgaag atccgagagc
    10201 gaaataagcc agagatcttt gaagttatcc gggacgtctt cacagtgaac aaagctgccc
    10261 atgtgcagca gatgaaaaca gtgaagcaga gtgtactgga tggcacctcc aaatggtcag
    10321 ccaagatcac cattactgtg gtgtgtgccc agggcctaca agccaaggac aaaacaggat
    10381 ccagtgaccc ttacgtgact gtgcaagtca gcaaaactaa gaagcgtacc aagaccattt
    10441 ttggaaactt gaatcctgtt tgggaggaga agttccattt tgagtgccac aactcctctg
    10501 accgcattaa ggtgcgtgta tgggatgagg atgatgacat caagtcaaga gtaaagcaac
    10561 gcctaaagcg agagtctgat gatttccttg gccaaaccat cattgaggtt cggaccctaa
    10621 gtggcgagat ggacgtctgg tacaacttgg agaagaggac agacaaatca gccgtctcag
    10681 gggctatccg actacaaatc agtgtggaga tcaaggggga ggagaaagta gccccatacc
    10741 acgtgcagta tacatgtctc catgagaatc ttttccatta cctcacagac attcagggca
    10801 gtggaggagt ccgcatccct gaagctcgag gagacgatgc ctggaaggtg tactttgatg
    10861 agacagccca agaaattgtg gatgaatttg ccatgcgtta tggcattgag tccatatatc
    10921 aggccatgac gcactttgca tgtttatcat ccaagtacat gtgtcctggt gtgccagcag
    10981 tgatgagcac cttactggcc aacatcaacg cctactatgc ccacacaact gcctctacca
    11041 atgtctctgc atctgatcgc tttgcagcct ccaactttgg gaaagagaga tttgtaaaac
    11101 tgctggacca gctacacaac tcactgagga tcgacctctc tacatacagg aataatttcc
    11161 ctgctgggag tcctgaacgg cttcaggact taaaatccac agtggatttg ctgaccagca
    11221 ttactttctt cagaatgaag gtacaagaac tgcaaagccc tccaagagcc agccaggtgg
    11281 taaaggattg tgtgaaggcc tgtttgaact ccacatatga atatatcttc aacaactgcc
    11341 acgacttata cagccgccag taccagctga agcaggagct acctccagag gaacaagggc
    11401 ccagcattcg gaacctggat ttctggccca agctcatcac actcatcgtg tcaatcatag
    11461 aggaagataa gaattcctac acacctgttc tgaaccagtt tcctcaggag ttgaatgtgg
    11521 gaaaagtcag cgcagaagtg atgtggcatt tgtttgccca agacatgaaa tatgcattgg
    11581 aggagcatga gaaagaccac ctgtgtaaaa gtgctgacta catgaacctg cacttcaagg
    11641 tgaagtggct ccacaatgaa tacgtgcggg atctgcctgt cctccagggg caggtgcctg
    11701 agtacccagc gtggtttgag cagttcgtgc tacaatggct ggatgagaat gaggatgtat
    11761 ccctggaatt cctgcgtggg gccctggaac gagataagaa ggatggattc cagcagacat
    11821 cagagcatgc actcttttcc tgctctgtgg tggatgtctt cacacaactc aatcagagct
    11881 ttgagatcat ccggaagctg gaatgcccag accccagcat ccttgcccac tacatgagga
    11941 ggtttgctaa gaccatcggg aaggtgctga tgcagtatgc agacatcttg tcaaaggact
    12001 tcccagccta ttgcacaaag gagaaactgc cctgcatcct gatgaacaac gtgcagcaac
    12061 tgagggtcca gctggagaaa atgtttgagg ccatgggagg caaggagctg gaccttgaag
    12121 ctgcagacag tctgaaggag ctgcaggtga aactgaatac ggttctggat gagctcagca
    12181 tggtgtttgg aaacagtttc caggtacgga ttgatgagtg tgttcgacaa atggccgaca
    12241 tcctgggcca ggttcggggc acagggaatg catctccaga cgccagggcc tcagcggctc
    12301 aggatgcaga tagcgtactc cggcctctca tggacttcct ggatggcaac ctcaccctct
    12361 ttgccactgt gtgtgagaag acggttctga agcgtgtact gaaggagctc tggcgcgtgg
    12421 tgatgaacac aatggagagg atgattgttc tgcccccact cactgaccag acgggcaccc
    12481 agctgatctt cactgctgcc aaggagctga gccatctttc caaactcaag gatcacatgg
    12541 tacgagagga aacacggaat ctcactccaa agcagtgtgc agtccttgac ctcgccctgg
    12601 acaccatcaa gcaatacttc catgcaggag gcaatgggct gaagaaaacc ttcctggaga
    12661 agagcccaga tctgcagtct ctacgctatg ccctgtctct gtacacacag actactgaca
    12721 ctctcatcaa gacctttgtg cgctcgcaga ccacccaagg gtctggtgtg gacgatcctg
    12781 tgggagaagt ctctattcag gtggacttgt ttacacaccc tggtactggg gagcacaagg
    12841 tcacagtgaa agtggtggct gccaatgacc tcaagtggca gacagcgggt atgttccggc
    12901 ctttcgtgga ggtgactatg gttggcccac accaaagtga taagaagagg aagttcacaa
    12961 ccaaatccaa aagcaacaac tgggccccca agtacaatga gacattccac ttcctcctgg
    13021 gaaatgagga ggggcccgag tcctatgagt tgcagatatg cgtgaaggat tactgctttg
    13081 cccgggaaga tcgcgtgcta gggctggctg tgatgcctct gagggatgtc acagccaagg
    13141 gcagctgtgc ctgctggtgc cccttgggcc ggaagatcca tatggatgag acaggcctga
    13201 ccattctccg gattttatct cagaggagca atgacgaggt ggcccgagaa tttgtgaaac
    13261 tcaaatcaga gtctcgttcc acggaggagg ggagctgaac accttcgact cctgtgccaa
    13321 tcaggcagca gcaatttcac aaatcagggc cagtgggagt tagctgtgta accggcttag
    13381 ggtctttgca gtcaagaggc tgaccccttc agttaaagat atttaaggaa aaatttgggg
    13441 tggtgataat atggcttttc acagaaaggg tcatgaagcc ctggcccaac aggactgtgg
    13501 tactaggggc tgggatgtgg ggttaccaca tggagagatt ttccattaag agagaaggac
    13561 aaacatttct gagagtgtca gccattcttg gtagacacct ctccactcct catcccacct
    13621 ctacccatct ccatgccaca ccttatccag ttagacacat acataccaat cattagaaga
    13681 acaagtttag aaggtgtgga acttgtgcct ggctggctgg gtagtcagct gagcctgttg
    13741 ctgagcccgg tggtctggat tggagtatgg ccagggcagg agtacacaga atagaattta
    13801 gactgtccct tgagtagaat ccactgattt tctgtggctc cagtgagaac aaggctttga
    13861 aactgaacaa gataacttct agaaatgaac tgtactaatc cctttcccca gattgtatca
    13921 tgagtagaat caggttcacg tggtgcttca aagccctgag aagaatattt ctttggaccc
    13981 caggcactag gggccacctg cctgggagtc tccctgcctc actcctctag gcaggggagt
    14041 gatgcttcag gacgtgacag gctgttctaa catgtgtcta cctgagggct agttgaagga
    14101 tccaggagta ttttcttctt gggtgggccc tgaacaaagc caaaaattgt agaaaccagt
    14161 ctagaaaaag tcctgctcat ctgtggccac tgccttctag ccgtcctcca ccttgcagaa
    14221 agaatctagc ctttggtctc tctctctctc atcggggtca tttgctattc ccctctgata
    14281 ttcaacccta tagaaggagc ctggactctg atccctctgt acaggctgga tggaaggggc
    14341 cctccacact tcctgggagg tcagagacaa actgtttcag agagtcagat ggacttccca
    14401 agacttgttg agagatgtga catggttctt ggatttcctc tgtagcagcc tcctggactt
    14461 cctgaggact cgacattgtc cacagatgta ctggccatta catgaaacaa gaaaccaagc
    14521 atctttgctg ttgttaatta ttatatgtgc cattgttaca ggagattata ggctagtctg
    14581 taataaatta tcttatagca
//
