LOCUS       XM_047438709            3766 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens ubiquitin like with PHD and ring finger
            domains 1 (UHRF1), transcript variant X4, mRNA.
ACCESSION   XM_047438709
VERSION     XM_047438709.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000019.10) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3766
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
     gene            1..3766
                     /gene="UHRF1"
                     /gene_synonym="hNP95; hUHRF1; huNp95; ICBP90; Np95;
                     RNF106; TDRD22"
                     /note="ubiquitin like with PHD and ring finger domains 1;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 3 mRNAs, 34 ESTs, 844 long SRA reads, 1
                     Protein, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments"
                     /db_xref="GeneID:29128"
                     /db_xref="HGNC:HGNC:12556"
                     /db_xref="MIM:607990"
     CDS             139..2415
                     /gene="UHRF1"
                     /gene_synonym="hNP95; hUHRF1; huNp95; ICBP90; Np95;
                     RNF106; TDRD22"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase UHRF1 isoform X1"
                     /protein_id="XP_047294665.1"
                     /db_xref="GeneID:29128"
                     /db_xref="HGNC:HGNC:12556"
                     /db_xref="MIM:607990"
                     /translation="MWIQVRTMDGRQTHTVDSLSRLTKVEELRRKIQELFHVEPGLQR
                     LFYRGKQMEDGHTLFDYEVRLNDTIQLLVRQSLVLPHSTKERDSELSDTDSGCCLGQS
                     ESDKSSTHGEAAAETDSRPADEDMWDETELGLYKVNEYVDARDTNMGAWFEAQVVRVT
                     RKAPSRDEPCSSTSRPALEEDVIYHVKYDDYPENGVVQMNSRDVRARARTIIKWQDLE
                     VGQVVMLNYNPDNPKERGFWYDAEISRKRETRTARELYANVVLGDDSLNDCRIIFVDE
                     VFKIERPGEGSPMVDNPMRRKSGPSCKHCKDDVNRLCRVCACHLCGGRQDPDKQLMCD
                     ECDMAFHIYCLDPPLSSVPSEDEWYCPECRNDASEVVLAGERLRESKKKAKMASATSS
                     SQRDWGKGMACVGRTKECTIVPSNHYGPIPGIPVGTMWRFRVQDHGNFFTYTGSGGRD
                     LSGNKRTAEQSCDQKLTNTNRALALNCFAPINDQEGAEAKDWRSGKPVRVVRNVKGGK
                     NSKYAPAEGNRYDGIYKVVKYWPEKGKSGFLVWRYLLRRDDDEPGPWTKEGKDRIKKL
                     GLTMQYPEGYLEALANREREKENSKREEEEQQEGGFASPRTGKGKWKRKSAGGGPSRA
                     GSPRRTSKKTKVEPYSLTAQQSSLIREDKSNAKLWNEVLASLKDRPASGSPFQLFLSK
                     VEETFQCICCQELVFRPITTVCQHNVCKDCLDRSFRAQVFSCPACRYDLGRSYAMQVN
                     QPLQTVLNQLFPGYGNGR"
ORIGIN      
        1 tgggcaccga ggggtcccgg ggtccgcgga tctcgggtgg ggtttttccc tctcagtggc
       61 acttggttga gttcccccgg gacttctgaa gttccggccc gcgctggact tctgggattc
      121 cctcttcccg ccgacaccat gtggatccag gttcggacca tggacgggag gcagacccac
      181 acggtggact cgctgtccag gctgaccaag gtggaggagc tgaggcggaa gatccaggag
      241 ctgttccacg tggagccagg cctgcagagg ctgttctaca ggggcaaaca gatggaggac
      301 ggccataccc tcttcgacta cgaggtccgc ctgaatgaca ccatccagct cctggtccgc
      361 cagagcctcg tgctccccca cagcaccaag gagcgggact ccgagctctc cgacaccgac
      421 tccggctgct gcctgggcca gagtgagtca gacaagtcct ccacccacgg tgaggcggcc
      481 gccgagactg acagcaggcc agccgatgag gacatgtggg atgagacgga attggggctg
      541 tacaaggtca atgagtacgt cgatgctcgg gacacgaaca tgggggcgtg gtttgaggcg
      601 caggtggtca gggtgacgcg gaaggccccc tcccgggacg agccctgcag ctccacgtcc
      661 aggccggcgc tggaggagga cgtcatttac cacgtgaaat acgacgacta cccggagaac
      721 ggcgtggtcc agatgaactc cagggacgtc cgagcgcgcg cccgcaccat catcaagtgg
      781 caggacctgg aggtgggcca ggtggtcatg ctcaactaca accccgacaa ccccaaggag
      841 cggggcttct ggtacgacgc ggagatctcc aggaagcgcg agaccaggac ggcgcgggaa
      901 ctctacgcca acgtggtgct gggggatgat tctctgaacg actgtcggat catcttcgtg
      961 gacgaagtct tcaagattga gcggccgggt gaagggagcc ccatggttga caaccccatg
     1021 agacggaaga gcgggccgtc ctgcaagcac tgcaaggacg acgtgaacag actctgccgg
     1081 gtctgcgcct gccacctgtg cgggggccgg caggaccccg acaagcagct catgtgcgat
     1141 gagtgcgaca tggccttcca catctactgc ctggacccgc ccctcagcag tgttcccagc
     1201 gaggacgagt ggtactgccc tgagtgccgg aatgatgcca gcgaggtggt actggcggga
     1261 gagcggctga gagagagcaa gaagaaggcg aagatggcct cggccacatc gtcctcacag
     1321 cgggactggg gcaagggcat ggcctgtgtg ggccgcacca aggaatgtac catcgtcccg
     1381 tccaaccact acggacccat cccggggatc cccgtgggca ccatgtggcg gttccgagtc
     1441 caggaccatg ggaatttttt cacatacacg ggtagtggtg gtcgagatct ttccggcaac
     1501 aagaggaccg cggaacagtc ttgtgatcag aaactcacca acaccaacag ggcgctggct
     1561 ctcaactgct ttgctcccat caatgaccaa gaaggggccg aggccaagga ctggcggtcg
     1621 gggaagccgg tcagggtggt gcgcaatgtc aagggtggca agaatagcaa gtacgccccc
     1681 gctgagggca accgctacga tggcatctac aaggttgtga aatactggcc cgagaagggg
     1741 aagtccgggt ttctcgtgtg gcgctacctt ctgcggaggg acgatgatga gcctggccct
     1801 tggacgaagg aggggaagga ccggatcaag aagctggggc tgaccatgca gtatccagaa
     1861 ggctacctgg aagccctggc caaccgagag cgagagaagg agaacagcaa gagggaggag
     1921 gaggagcagc aggagggggg cttcgcgtcc cccaggacgg gcaagggcaa gtggaagcgg
     1981 aagtcggcag gaggtggccc gagcagggcc gggtccccgc gccggacatc caagaaaacc
     2041 aaggtggagc cctacagtct cacggcccag cagagcagcc tcatcagaga ggacaagagc
     2101 aacgccaagc tgtggaatga ggtcctggcg tcactcaagg accggccggc gagcggcagc
     2161 ccgttccagt tgttcctgag taaagtggag gagacgttcc agtgtatctg ctgtcaggag
     2221 ctggtgttcc ggcccatcac gaccgtgtgc cagcacaacg tgtgcaagga ctgcctggac
     2281 agatcctttc gggcacaggt gttcagctgc cctgcctgcc gctacgacct gggccgcagc
     2341 tatgccatgc aggtgaacca gcctctgcag accgtcctca accagctctt ccccggctac
     2401 ggcaatggcc ggtgatctcc aagcacttct cgacaggcgt tttgctgaaa acgtgtcgga
     2461 gggctcgttc atcggcactg attttgttct tagtgggctt aacttaaaca ggtagtgttt
     2521 cctccgttcc ctaaaaaggt ttgtcttcct tttttttttt atttttattt ttcaaatcta
     2581 tacattttca ggaatttatg tattctggct aaaagttgga cttctcagta ttgtgtttag
     2641 ttctttgaaa acataaaagc ctgcaatttc tcgacaaaac aacacaagat tttttaaaga
     2701 tggaatcaga aactacgtgg tgtggaggct gttgatgttt ctggtgtcaa gttctcagaa
     2761 gttgctgcca ccaactcttt aagaaggcga caggatcagt ccttctctcg ggttctggcc
     2821 cccaaggtca gagcaagcat cttcctgaca gcattttgtc atctaaagtc cagtgacatg
     2881 gttccccgtg gtggcccgtg gcagcccgtg gcatggcgtg gctcagctgt ctgttgaagt
     2941 tgttgcaagg aaaagaggaa acatctcggg cctagttcaa acctttgcct caaagccatc
     3001 ccccaccaga ctgcttagcg tctgagatcc gcgtgaaaag tcctctgccc acgagagcag
     3061 ggagttgggg ccacgcagaa atggcctcaa ggggactctg ctccacgtgg ggccaggcgt
     3121 gtgactgacg ctgtccgacg aaggcggcca cggacggacg ccagcacacg aagtcacgtg
     3181 caagtgcctt tgattcgttc cttctttcta aagacgacag tctttgttgt tagcactgaa
     3241 ttattgaaaa tgtcaaccag attctagaaa ctgcggtcat ccagttcttc ctgacaccgg
     3301 atgggtgctt gggaaccgtt tgagccttat agatcattta cattcaattt ttttaactca
     3361 gcaagtgaga acttacaaga gggttttttt aaaatttttt tttctcttaa tgaacacatt
     3421 ttctaaatga attttttttg tagttactgt atatgtacca agaaagatat aacgttaggg
     3481 tttggttgtt tttgtttttg tatttttttt cttttgaaag ggtttgttaa tttttctaat
     3541 tttaccaaag tttgcagcct atacctcaat aaaacaggga tattttaaat cacatacctg
     3601 cagacaaact ggagcaatgt tatttttaaa gggttttttt cacctcctta ttcttagatt
     3661 attaatgtat tagggaagaa tgagacaatt ttgtgtaggc tttttctaaa gtccagtact
     3721 ttgtccagat tttagattct cagaataaat gtttttcaca gataga
//
