LOCUS       XM_047416134            4324 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens UDP glycosyltransferase 8 (UGT8),
            transcript variant X3, mRNA.
ACCESSION   XM_047416134
VERSION     XM_047416134.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000004.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4324
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
     gene            1..4324
                     /gene="UGT8"
                     /gene_synonym="CGT; UGT4"
                     /note="UDP glycosyltransferase 8; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 3
                     mRNAs, 14 ESTs, 740 long SRA reads, 14 Proteins, and 99%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 3 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:7368"
                     /db_xref="HGNC:HGNC:12555"
                     /db_xref="MIM:601291"
     CDS             762..2387
                     /gene="UGT8"
                     /gene_synonym="CGT; UGT4"
                     /codon_start=1
                     /product="2-hydroxyacylsphingosine
                     1-beta-galactosyltransferase isoform X1"
                     /protein_id="XP_047272090.1"
                     /db_xref="GeneID:7368"
                     /db_xref="HGNC:HGNC:12555"
                     /db_xref="MIM:601291"
                     /translation="MKSYTPYFILLWSAVGIAKAAKIIIVPPIMFESHMYIFKTLASA
                     LHERGHHTVFLLSEGRDIAPSNHYSLQRYPGIFNSTTSDAFLQSKMRNIFSGRLTAIE
                     LFDILDHYTKNCDLMVGNHALIQGLKKEKFDLLLVDPNDMCGFVIAHLLGVKYAVFST
                     GLWYPAEVGAPAPLAYVPEFNSLLTDRMNLLQRMKNTGVYLISRLGVSFLVLPKYERI
                     MQKYNLLPEKSMYDLVHGSSLWMLCTDVALEFPRPTLPNVVYVGGILTKPASPLPEDL
                     QRWVNGANEHGFVLVSFGAGVKYLSEDIANKLAGALGRLPQKVIWRFSGPKPKNLGNN
                     TKLIEWLPQNDLLGHSKIKAFLSHGGLNSIFETIYHGVPVVGIPLFGDHYDTMTRVQA
                     KGMGILLEWKTVTEKELYEALVKVINNPSYRQRAQKLSEIHKDQPGHPVNRTIYWIDY
                     IIRHNGAHHLRAAVHQISFCQYFLLDIAFVLLLGAALLYFLLSWVTKFIYRKIKSLWS
                     RNKHSTVNGHYHNGILNGKYKRNGHIKHEKKVK"
     polyA_site      4324
                     /gene="UGT8"
                     /gene_synonym="CGT; UGT4"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 gtcagagttc gcaactcgag cgcccagagg gctcgcgaaa agtcccagcc tgcaagccaa
       61 cctcgctcag cggacgactg gccggatccc aacgcgctgc cccttgccca gcctgcgagc
      121 gcgtggtacg aaggcgcgtc tgcatccatg ccccagcccg gggagctgga ggcgctcgca
      181 gtcagaggcg agtgatgcta ggctgagcgc gtggcggccc gtgtcgtgcc ccgctgagcc
      241 aagtgcggaa gggcagcggc gcgctccgac tctgctcgcc gcacgcaggg cggggcgcgg
      301 ctggggggcg gggggcctgg ccgcccgctg ggagctgcgg acgagcaggc gcgctgagga
      361 cccgagggag gacacggtta aagcattgct atcaactgtg aacccagaga gccctcctta
      421 gccaacacgc taactccgaa gcctccctta cgcccccgaa ccaccgaagg cggcgacacc
      481 tgattcagcg cacaaacaca ggtcccttct gtcccggata caattacgcg gcagacacac
      541 actcaaactc gcgcggggca gccaagagac gaggtgagcg gagggaccac gccgttccag
      601 agggcggaag ggggggcggt ctgggtggag gagaggggcg ttgtttgctc cctgagtgag
      661 agtaacacat gcgcactgtg gattcctttg tgaatacata aaaggaaaag ttaaaactct
      721 tataattcac actatccaga gaaaaacaat actattttgc tatgaagtct tacactccat
      781 atttcattct cctgtggagt gctgttggga tagcgaaggc tgccaaaatc atcatcgtgc
      841 cgccaattat gtttgaaagc catatgtaca ttttcaagac gctagcctca gccttgcacg
      901 agagaggcca ccatacagtg ttcctcctct ctgaaggcag agacatcgcc ccatctaatc
      961 attacagcct ccagcgctac ccagggatct ttaacagtac cacctcagat gctttcctac
     1021 agtccaagat gcggaatatt ttctctggga gattgacagc aatcgaactg tttgacatac
     1081 tggatcacta tactaagaac tgtgacctga tggttggcaa ccatgccctg atccagggtc
     1141 tgaagaaaga aaaatttgac ctgctgctgg tggaccctaa tgatatgtgt ggatttgtga
     1201 tagctcatct tttaggggtt aaatatgctg tattttcaac tggcctttgg tatcctgctg
     1261 aagtgggtgc tcctgctcca ttagcatacg tcccagagtt taactcactc ctcacagacc
     1321 gcatgaactt gctgcaaagg atgaaaaata ccggtgttta cctcatttcc agattagggg
     1381 tcagctttct ggttcttccc aaatatgaaa ggataatgca gaagtacaac ctgctgccag
     1441 agaagtccat gtatgatttg gttcatgggt ccagcctgtg gatgctgtgt actgacgtag
     1501 cactggaatt cccaagaccc actctgccta atgttgttta tgtaggagga atcctaacca
     1561 aaccagccag cccactacca gaagatctcc aaagatgggt aaatggtgct aatgaacatg
     1621 gctttgtctt ggtgtctttt ggagctggtg tcaagtatct gtcagaagac attgctaaca
     1681 aactggcagg agctctgggg agattgcctc aaaaagtgat ttggaggttt tctggaccca
     1741 aaccaaagaa tctaggaaac aacactaaac tcatagaatg gttaccacaa aatgacctgc
     1801 ttgggcattc aaagattaaa gccttcctga gccatggtgg tttgaacagt atttttgaaa
     1861 ctatatatca tggtgtgcct gtagtgggaa ttccactctt tggagaccat tatgatacta
     1921 tgaccagagt acaggcaaaa ggcatgggga tattgctaga atggaagaca gttactgaaa
     1981 aagagctcta tgaagcacta gtgaaggtta tcaataatcc cagctaccgt cagagggctc
     2041 agaagctttc ggaaattcac aaggatcaac ctggtcaccc tgtcaatcga actatctatt
     2101 ggatagatta tattattcgt cacaatggag cccatcacct acgtgccgct gtccatcaga
     2161 tctccttttg tcagtatttt ttactggata ttgcctttgt gcttttgctt ggtgctgcct
     2221 tgttatactt tctcttgtct tgggtgacaa aatttatcta cagaaaaatc aaaagtctgt
     2281 ggtctagaaa taagcatagc acagttaatg gacattacca caatggaatc ctcaatggca
     2341 agtacaaaag aaatggccat attaaacatg aaaagaaagt gaaatgagcc aacagcccag
     2401 gtgatagaaa taaattggtt cactcattga atttttattg ctattattta gtctaacagc
     2461 tactaaaagt aaaacatcag taaacaattc taacatgccc ttatgagatc tactaatgaa
     2521 attctgtgga attaagatgg ctgtaaaaag cacaaaccta aaatgcagaa atgtatttta
     2581 ttcaaatact gatgtagaga gttttggcac tgaacctttt agaagcctta attatttaaa
     2641 tcaattcagt gactgtgtca gaccttagtt ttaaatcttg atatgtgcgt gtcccggatc
     2701 aggaatggtt tcatttttct taataatgtg tgtgtgtgta tgtgtgtgtg tgtgtgtgtg
     2761 tgtttgtgtg tgtgtgtgtg tgtcctaatt aagagaattt ttactggctg cttgttacat
     2821 ttgttgaggg tacaacacac tcaagaataa agtaaaagga tagtcaggat ccagatgttt
     2881 cttttctagc atttaatgtg tgtgaactca gaacactacc atgaaagaac acttcccccc
     2941 aaaactggat gcagaggaag aaaaaaaaaa aagaaatggc acagtttttt gtattttttt
     3001 ttttagttat tttttgttgt tgttgtttgt attgtttttc ttttctgata gagtatggcc
     3061 acttctgggg gaaaaacatg taattaagta aatgtataca ttggttttca cgttttactt
     3121 ttgttttccc actaccaata attttcctct ggaagaattt tatagttttt tctatttcat
     3181 tttaatgagt aacaatatgt taaatgcata attaagacaa agcaatgaaa ttctgacttt
     3241 attcaaagta ctgaagatta ttgcttctag ggcattttta aacagcacca ttgtattgtt
     3301 gaatgtttat gtaactgatg gcttttctat aatgtaattt ttgaatgttc aggtgttaca
     3361 tttccaaagt ttaactttta aaaaaccatc ttctgatccc ttttattgtc tgggccatac
     3421 aatctatatt acataggtgc caacatttaa ttcttttaaa tggaacattt gcagttttcc
     3481 atattggtac ctgctttttc tggagaggtt tgagatcttg ttaacaaatc agactttaca
     3541 ctatatacag atgtgacaga taaattgaac cacttgtttg tgaaaatgag ttcctgtcat
     3601 cttcctcatt cactcagccc tcaccccagc agccttttcc ggtcattgta gctgacatgg
     3661 agcagtgaca gtattcattt gagaacaggg atgcaagtca cagacatcat aaaatcaggg
     3721 tctccctgct gaagcattca ctagttggca actatgaatt tattccatgt cattctgttt
     3781 acttagcact tgcactaccc ttgttggttg agtgtatgct ttatttgttt ctagtttgaa
     3841 atcccacatc tgatagctga gagtaggcaa atacaacatt tacctaatgt cattcactaa
     3901 catggaagag ttgtgaaaat tctagagtgc tgtaaatcct tggcatacac tatgacaaac
     3961 aacttcatta ctctcccacc aggagctgct ctcctgcact tagaaataat gtcacaagta
     4021 gttttctaat gtacaatgca gacaaatgta ctgctctctg aatacttgaa gaaatggtat
     4081 tatacataca tagaaactta ttagttatac cttttcacaa tcttattacg atgttgccgt
     4141 taaaagggaa aaaagacaca ggcaatgaat ggtgggatag taagaggact tagagtgtat
     4201 gaatgagttg attttacttt tttggaattt gattaagttg acagtaggca ctgattggat
     4261 gattaaacat aagttaatct ccactgtgat aaaaacttaa ataataaaca tgatttaaaa
     4321 taga
//
