LOCUS       XM_011514440            6196 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens ubiquitin protein ligase E3 component
            n-recognin 2 (UBR2), transcript variant X5, mRNA.
ACCESSION   XM_011514440
VERSION     XM_011514440.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000006.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011514440.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6196
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
     gene            1..6196
                     /gene="UBR2"
                     /gene_synonym="bA49A4.1; C6orf133; dJ242G1.1; dJ392M17.3"
                     /note="ubiquitin protein ligase E3 component n-recognin 2;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 1 mRNA, 43 ESTs, 1346 long SRA reads, 1
                     Protein, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 75 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:23304"
                     /db_xref="HGNC:HGNC:21289"
                     /db_xref="MIM:609134"
     CDS             85..3864
                     /gene="UBR2"
                     /gene_synonym="bA49A4.1; C6orf133; dJ242G1.1; dJ392M17.3"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase UBR2 isoform X5"
                     /protein_id="XP_011512742.1"
                     /db_xref="GeneID:23304"
                     /db_xref="HGNC:HGNC:21289"
                     /db_xref="MIM:609134"
                     /translation="MYAGNIPIYKTESRSRNEQGMDPITRQVGQHIEMEPEWEAAFTL
                     QMKLTHVISMMQDWCASDEKVLIEAYKKCLAVLMQCHGGYTDGEQPITLSICGHSVET
                     IRYCVSQEKVSIHLPVSRLLAGLHVLLSKSEVAYKFPELLPLSELSPPMLIEHPLRCL
                     VLCAQVHAGMWRRNGFSLVNQIYYYHNVKCRREMFDKDVVMLQTGVSMMDPNHFLMIM
                     LSRFELYQIFSTPDYGKRFSSEITHKDVVQQNNTLIEEMLYLIIMLVGERFSPGVGQV
                     NATDEIKREIIHQLSIKPMAHSELVKSLPEDENKETGMESVIEAVAHFKKPGLTGRGM
                     YELKPECAKEFNLYFYHFSRAEQSKAEEAQRKLKRQNREDTALPPPVLPPFCPLFASL
                     VNILQSDVMLCIMGTILQWAVEHNGYAWSESMLQRVLHLIGMALQEEKQHLENVTEEH
                     VVTFTFTQKISKPGEAPKNSPSILAMLETLQNAPYLEVHKDMIRWILKTFNAVKKMRE
                     SSPTSPVAETEGTIMEESSRDKDKAERKRKAEIARLRREKIMAQMSEMQRHFIDENKE
                     LFQQTLELDASTSAVLDHSPVASDMTLTALGPAQTQVPEQRQFVTCILCQEEQEVKVE
                     SRAMVLAAFVQRSTVLSKNRSKFIQDPEKYDPLFMHPDLSCGTHTSSCGHIMHAHCWQ
                     RYFDSVQAKEQRRQQRLRLHTSYDVENGEFLCPLCECLSNTVIPLLLPPRNIFNNRLN
                     FSDQPNLTQWIRTISQQIKALQFLRKEESTPNNASTKNSENVDELQLPEGFRPDFRPK
                     IPYSESIKEMLTTFGTATYKVGLKVHPNEEDPRVPIMCWGSCAYTIQSIERILSDEDK
                     PLFGPLPCRLDDCLRSLTRFAAAHWTVASVSVVQGHFCKLFASLVPNDSHEELPCILD
                     IDMFHLLVGLVLAFPALQCQDFSGISLGTGDLHIFHLVTMAHIIQILLTSCTEENGMD
                     QENPPCEEESAVLALYKTLHQYTGSALKEIPSGWHLWRSVRAGIMPFLKCSALFFHYL
                     NGVPSPPDIQVPGTSHFEHLCSYLSLPNNLICLFQENSEIMNSLIESWCRNSEVKRYL
                     EGERDAIRYPRESNKLINLPEDYSSLINQASNFSCPKSGGDKSRAPTLCLVCGSLLCS
                     QSYCCQTELEGEDVGACTAHTYSCGSGVGIFLRVRECQVLFLAGKTKGCFYSPPYLDD
                     YGETDQGLRRGNPLHLCKERFKKIQKLWHQHSVTEEIGHAQEANQTLVGIDWQHL"
ORIGIN      
        1 gttaattagc aaaccaactg aatggtcaga tgagctgagg cagaagttcc tagaagggtt
       61 tgatgccttt ttggaattac taaaatgtat gcaggaaaca tccctatata caaaacagaa
      121 tctagaagta gaaacgaaca gggaatggat ccaattacac gtcaagtagg acaacatatt
      181 gaaatggaac cagagtggga agcagccttc acactacaaa tgaaattaac acatgtcatt
      241 tcaatgatgc aggactggtg tgcttcagat gaaaaagtgt taatcgaagc ttacaagaaa
      301 tgtctcgctg tactgatgca gtgtcatggt ggttatactg atggtgaaca gccaatcaca
      361 ctaagcattt gtggacattc agtggaaact atcagatact gtgtttccca agaaaaagtt
      421 agcattcacc tcccagtttc tcgcttactt gcaggtttac atgtattatt aagcaaaagt
      481 gaagtggcat ataaatttcc agagctccta cctctaagtg aacttagccc acccatgttg
      541 atagaacacc ctcttagatg tcttgttctg tgtgcccaag tacatgccgg aatgtggaga
      601 agaaatgggt tctctctagt aaaccagatt tattactacc ataatgtgaa atgcagacgt
      661 gagatgtttg acaaggatgt agtaatgctt cagacaggtg tctccatgat ggatccaaat
      721 catttcctga tgatcatgct cagccgcttt gaactttatc agattttcag tactccagac
      781 tatggaaaaa gatttagttc tgagattacc cataaggatg ttgttcagca gaacaatact
      841 ctaatagaag aaatgctata cctcattata atgcttgttg gagagagatt tagtcctgga
      901 gttggacagg taaatgctac agatgaaatc aagcgagaga ttatccatca gttgagtatc
      961 aagcctatgg ctcatagtga attggtaaag tctttacctg aagatgagaa caaggagact
     1021 ggcatggaga gtgtaatcga agcagttgcc catttcaaga aacctggatt aacaggacga
     1081 ggcatgtatg aactgaaacc agaatgtgcc aaagagttca acttgtattt ctatcacttt
     1141 tcaagggcag aacagtccaa ggcagaagaa gcgcaacgga aattgaaaag acaaaataga
     1201 gaagatacag cactcccacc tccggtgttg cctccattct gccctctgtt tgcaagcctg
     1261 gttaacattt tgcagtcaga tgtcatgttg tgcatcatgg gaacaattct gcaatgggct
     1321 gtggaacata atggatatgc ctggtcagag tccatgctgc aaagggtgtt acatttaatt
     1381 ggcatggcac tacaagaaga aaaacaacat ttagagaatg tcacggaaga gcatgtagta
     1441 acatttacct tcactcagaa gatatcaaaa cctggtgaag cgccaaaaaa ttctcctagc
     1501 atactagcta tgctggaaac actacaaaat gctccctacc tagaagtcca caaagacatg
     1561 attcggtgga tattgaagac ttttaatgct gttaaaaaga tgagggagag ttcacctacc
     1621 agtcccgtgg cagagacaga aggaaccata atggaagaga gttcaaggga caaagacaaa
     1681 gctgagagga agagaaaagc agagattgcc agactgcgca gagaaaagat catggctcag
     1741 atgtctgaaa tgcagcggca ttttattgat gaaaacaaag aactctttca gcagacatta
     1801 gaactggatg cctcaacctc tgctgttctt gatcatagcc ctgtggcttc agatatgaca
     1861 cttacagcac tgggccccgc acaaactcag gttcctgaac aaagacaatt cgttacatgt
     1921 atattgtgtc aagaggagca agaagttaaa gtggaaagca gggcaatggt cttggcagca
     1981 tttgttcaga gatcaactgt attatcaaaa aacagaagta aatttattca agatccagaa
     2041 aaatatgatc cattattcat gcaccctgat ctgtcttgtg gaacacacac tagtagctgt
     2101 gggcacatta tgcatgccca ttgttggcaa aggtattttg attccgttca agctaaagaa
     2161 cagcgaaggc aacagagatt acgcttacat acgagctatg atgtagaaaa cggagaattc
     2221 ctttgccccc tttgtgaatg cttgagtaat actgttattc ctctgctgct tcctccaaga
     2281 aatattttta acaacaggtt aaatttttca gaccaaccaa atctgactca gtggattaga
     2341 acaatatctc agcaaataaa agcattacag tttcttagga aagaagaaag tactcctaat
     2401 aatgcctcta caaagaattc agaaaatgtg gatgaattac agctccctga agggttcagg
     2461 cctgattttc gtcctaagat cccttattct gagagcataa aagaaatgct aacgacattt
     2521 ggaactgcta cctacaaggt gggactaaag gttcatccca atgaagagga tcctcgtgtt
     2581 cccataatgt gttggggtag ctgcgcgtac accatccaaa gcatagaaag aattttgagt
     2641 gatgaagata aaccattgtt tggtccttta ccttgcagac tggatgactg tcttaggtca
     2701 ttgacgagat ttgccgcagc acactggaca gtggcatcag tttcagtggt gcaaggacat
     2761 ttttgtaaac tttttgcatc actggtgcct aatgacagcc atgaggaact tccatgcata
     2821 ttagatattg acatgtttca tttattggtg ggcttggtgc ttgcatttcc tgcgttgcag
     2881 tgtcaggatt tttcagggat cagccttggc actggagacc ttcacatttt ccatctggtt
     2941 actatggcac acatcataca gatcttactt acctcatgta cagaagagaa tggcatggat
     3001 caagaaaatc ccccttgtga agaagaatca gcagttcttg ctttgtataa aacacttcac
     3061 cagtatacgg gaagtgcctt gaaagaaata ccatccggct ggcatctgtg gaggagtgtc
     3121 agagctggaa tcatgccttt cctgaagtgt tctgctttat tttttcatta cttaaatgga
     3181 gttccttccc cacccgacat tcaagttcct ggaacaagcc attttgaaca tttatgtagc
     3241 tatctttccc taccaaacaa cctcatttgc ctttttcaag aaaatagtga gataatgaat
     3301 tcactgattg aaagttggtg ccgtaacagt gaagttaaaa gatatctaga aggtgaaaga
     3361 gatgctataa gatatccaag agaatctaac aaattaataa accttccaga ggattacagc
     3421 agcctcatta atcaagcatc caatttctcg tgcccgaaat caggtggtga taagagcaga
     3481 gccccaactc tgtgccttgt gtgcggatct ctgctgtgct cccagagtta ctgctgccag
     3541 actgaactgg aaggggagga tgtaggagcc tgcacagctc acacctactc ctgtggctct
     3601 ggagtgggca tcttcctgag agtacgggaa tgtcaggtgc tatttttagc tggcaaaacc
     3661 aaaggctgtt tttattctcc tccttacctt gatgactatg gggagaccga ccagggactc
     3721 agacggggaa atcctttaca tttatgcaaa gagcgattca agaagattca gaagctctgg
     3781 caccaacaca gtgtcacaga ggaaattgga catgcacagg aagccaatca gacactggtt
     3841 ggcattgact ggcaacattt ataattattg caccaccaaa aaacacaaac ttggattttt
     3901 ttaacccagt tggcttttta agaaagaaag aagttctgct gaatttggaa ataaattctt
     3961 tatttaaact ttccttccca gttttatagt ttctggttct gaggactgat gaaaatcatc
     4021 ttccatcagc agattttctt gcactgtttg ctgtgcccct caaatataat gtcttgggtt
     4081 ttaagatcga gcaaggagct tctcttccta gattggatcc cagccccttt gtgggggtct
     4141 gactgcatag tcccagccat tatgtgatat ttcacgttat tgatgatagt gaaccgtggg
     4201 tccgaagctg actcaacgga ggcagggaac aaagtctctg tggtctgttg ggtcatactt
     4261 cctggttcca ctgagtggcc caacactggg actgggttgg tgtcccctct gctgacagga
     4321 ccctactcct aggagcaaag tggttgattt tgaaggcagt gttcccttct ctccattgac
     4381 tatgagagag ttgggggaca cacatgcaga agaagcccgt ggggagaagg tggattcctg
     4441 gtgtgctggc tggtttttca gggctgttag aggttttttt tttttctttt tttttttatg
     4501 gcaagacttt tggctttgag aaaactcact tagagggctt tccaaaaact taggatggtc
     4561 taaaaaatta ggatattctt ttagaattag gaagaaaaat taggatattc taaaagaata
     4621 tggattaaaa atttaggata ttcttttaga tatcctaata tctagatgag aggccttcct
     4681 tcataagatc tggttgtttg ggctgtggtt ggcataagtg atatttattt tggcctctgt
     4741 cacatccagt ttcttgagct tttaaggtaa gcttcttttg gctttttttc agatgttcac
     4801 caagcttaag tttaaaataa taggtattct aaaagagtat cctaattttc ttatctgtat
     4861 tcttttagaa taccctaatg tttcagacag tgatattctc ttgttatttc taaggctaaa
     4921 ttggcagagt atatcatcta aagccaaaca ctgaagaagg tgagaaccca ctcccaccca
     4981 gccagcattt cctggaacag acaagctgct gcttccttgc tggctcactt agtgcattcc
     5041 tgggatggtc tggcacccag gctttttatt ctttttgatc attgttctta ctgaggtgcc
     5101 ttcctagaac aagagccact tacaaaatag cttataatta ttatgtacca cacaactact
     5161 attgtttgat gtatgactgc tgagagcttg aatacatgca gagagtgact gaagacttag
     5221 tagaggaata aattctgagc ctgtctaagg tggggctaag gaacagatga gtaataagag
     5281 gctcttggat ttttttaacc aatgcaactg accctttcaa tcagttttct ttgaattaca
     5341 tctacaagtt ttgttccact cagctaccag tcaactaggc atgctccaca gtatcacagg
     5401 aagaaggtca gaaatctgga actgaagcta aaagaagtga ggatgtagaa gccacattcc
     5461 tctccaaggt agtgtgtgaa agaaccgccc cctcttgaca ggaggatgac cgtcgccatt
     5521 cttgcgtggg actgactcac ccagctgaga ggaggaccaa tagaaagaaa attcacattt
     5581 gagtccacct ctctccccct ttttctggcc ttcattcata agatctggtt gtttgggctg
     5641 taggtggcat aattcatgtt tattttggcc tctgtcacat ccagtttctt tagcttttaa
     5701 ggtaagcttc ttttggcttt ttttcatatg ttcaccaagc taaaatttaa aataataaga
     5761 ccaggtttct ctctgtacaa gtggattata aacattttca ccaaatcata acaatactcc
     5821 agctttccgg tccgacttcc taggagcctg gagttagcaa aggttgtctc tggatttcat
     5881 tctctgagaa tatcacagag cctgggagaa gatgaattta catgaaattg caacatacac
     5941 acctttttat tttctggtgt taagctagtt gtctttccta ccttacaaat catgttagtt
     6001 ttatgatttg ttccgcatgt tttatgttta ttgtagaaat gtttatataa catacgcttt
     6061 ccatatcagg gaaaatcata tctgtttaat aaattggcta taactttaat atctgtggac
     6121 aacttgtaaa atttggaatg tatcatatgt aaaaagttta aagatatcca aataaatgct
     6181 ttaggtgttg gcatta
//
