LOCUS       XM_047429844            6664 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens ubiquitin protein ligase E3B (UBE3B),
            transcript variant X3, mRNA.
ACCESSION   XM_047429844
VERSION     XM_047429844.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000012.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6664
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
     gene            1..6664
                     /gene="UBE3B"
                     /gene_synonym="BPIDS; KOS"
                     /note="ubiquitin protein ligase E3B; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 2
                     mRNAs, 67 ESTs, 674 long SRA reads, 1 Protein, and 99%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 11 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:89910"
                     /db_xref="HGNC:HGNC:13478"
                     /db_xref="MIM:608047"
     CDS             604..3798
                     /gene="UBE3B"
                     /gene_synonym="BPIDS; KOS"
                     /codon_start=1
                     /product="ubiquitin-protein ligase E3B isoform X2"
                     /protein_id="XP_047285800.1"
                     /db_xref="GeneID:89910"
                     /db_xref="HGNC:HGNC:13478"
                     /db_xref="MIM:608047"
                     /translation="MFTLSQTSRAWFIDRARQAREERLVQKERERAAVVIQAHVRSFL
                     CRSRLQRDIRREIDDFFKADDPESTKRSALCIFKIARKLLFLFRIKEDNERFEKLCRS
                     ILSSMDAENEPKVWYVSLACSKDLTLLWIQQIKNILWYCCDFLKQLKPEILQDSRLIT
                     LYLTMLVTFTDTSTWKILRGKGESLRPAMNHICANIMGHLNQHGFYSVLQILLTRGLA
                     RPRPCLSKGTLTAAFSLALRPVIAAQFSDNLIRPFLIHIMSVPALVTHLSTVTPERLT
                     VLESHDMLRKFIIFLRDQDRCRDVCESLEGCHTLCLMGNLLHLGSLSPRVLEEETDGF
                     VSLLTQTLCYCRKYVSQKKSNLTHWHPVLGWFSQSVDYGLNESMHLITKQLQFLWGVP
                     LIRIFFCDILSKKLLESQEPAHAQPASPQNVLPVKSLLKRAFQKSASVRNILRPVGGK
                     RVDSAEVQKVCNICVLYQTSLTTLTQIRLQILTGLTYLDDLLPKLWAFICELGPHGGL
                     KLFLECLNNDTEESKQLLAMLMLFCDCSRHLITILDDIEVYEEQISFKLEELVTISSF
                     LNSFVFKMIWDGIVENAKGETLELFQSVHGWLMVLYERDCRRRFTPEDHWLRKDLKPS
                     VLFQELDRDRKRAQLILQYIPHVIPHKNRVLLFRTMVTKEKEKLGLVETSSASPHVTH
                     ITIRRSRMLEDGYEQLRQLSQHAMKGVIRVKFVNDLGVDEAGIDQDGVFKEFLEEIIK
                     RVFDPALNLFKTTSGDERLYPSPTSYIHENYLQLFEFVGKMLGKAVYEGIVVDVPFAS
                     FFLSQLLGHHHSVFYSSVDELPSLDSEFYKNLTSIKRYDGDITDLGLTLSYDEDVMGQ
                     LVCHELIPGGKTIPVTNENKISYIHLMAHFRMHTQIKNQTAALISGFRSIIKPEWIRM
                     FSTPELQRLISGDNAEIDLEDLKKHTVYYGGFHGSHRVIIWLWDILASDFTPDERAMF
                     LKFVTSCSRPPLLGFAYLKPPFSIRCVEVSDDQQGRQLDPSEPSEEGPTVLTAGEPAS
                     PRETAHGLSPLSAAPFSFLPQGRVPGVGVGTCCF"
     polyA_site      6664
                     /gene="UBE3B"
                     /gene_synonym="BPIDS; KOS"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 gaacaccgcg gggcaagatg gcggtagtgc gtcggctgct gccccgggtc tggcagaact
       61 cgggtgtttt gggctgagac agtggcagct gcggccccga ccccaagtgc ggggacctcc
      121 ggcgaataaa ggtcggcctg cgggtaggcc ggtagggcct gcggtccggc ctgcgggaga
      181 actgggtcgt cagtcctccg agtggtgggg ctggggactt tgagggagtt ggctctaggg
      241 cacagtccct gcctggccag gtcggaggaa caagtgctgg gatctggcgt gtgtgctcca
      301 ggggctcttt ccgcggccct ttccacctct tttcactttg gggacggtag gcctttataa
      361 acggactaat gctgggtgat ttgttcctgt ggttgttgat gccgaggaaa gactctgggc
      421 cccaggactc acctaaactg gagttcgaat actgttcgct cgctgtgtga ccttggaaaa
      481 aataacaagc ttttctgaag tgagaagctg ttctcagcca cgagtcctgt gcaagatcac
      541 taatgattac ctggcatttc tgcgacacag gcaggtcctc agggtttgtg caagtttgca
      601 aacatgttca ccctgtctca gacctcgaga gcatggttca tcgatagagc ccgtcaggca
      661 cgagaagaaa ggcttgtgca gaaggaacgg gagcgggcag ctgttgtgat ccaggcccat
      721 gtccggagtt ttctctgtcg gagtcgactg cagagagata tcaggagaga gattgatgac
      781 ttttttaaag cagatgaccc tgagtccact aaaagaagtg cactttgtat tttcaagatt
      841 gccaggaaac tgctgttcct attcagaatc aaagaggata atgagagatt tgagaagttg
      901 tgtcgcagca tcctgagcag catggatgct gagaatgagc ctaaggtgtg gtatgtgtcc
      961 ctggcttgtt ctaaggacct caccctcctt tggattcaac agatcaagaa cattttgtgg
     1021 tactgctgtg attttctcaa gcagctcaag cctgaaatcc tgcaggactc ccgactcatc
     1081 accctgtacc tcacgatgct tgtcaccttc acagacactt caacgtggaa aattcttcgg
     1141 ggaaaaggtg aaagtcttcg accagcgatg aaccacattt gtgcaaatat aatgggacat
     1201 ctcaaccagc atggatttta ttctgtgctg cagatattgt taacccgtgg cctggcaaga
     1261 ccccgtcctt gtctatccaa aggcacttta acagcagctt tttctctagc gttacgccct
     1321 gtgattgctg cacagttctc agacaatctg attcggccgt tcctcatcca catcatgtct
     1381 gtgcctgctc tggtgactca tctcagcaca gtgacccctg agcgcctcac tgttttagaa
     1441 tcccatgaca tgcttcgtaa attcatcata tttttaagag accaagatcg atgccgtgat
     1501 gtatgtgaaa gtttagaagg atgccatacg ctttgtctaa tgggcaacct cctacacttg
     1561 ggctccctca gccccagagt gttagaggag gagacagatg ggttcgtgag tttgctcacc
     1621 cagacgctgt gctactgtcg gaagtatgtg tctcagaaga agtccaacct gacccactgg
     1681 catcctgtcc ttggctggtt ctcccaatct gtggattatg gccttaacga gtcaatgcac
     1741 ttgatcacca aacagctgca gttcttgtgg ggggtgcctc tgatccggat cttcttctgt
     1801 gacatcctga gcaagaagct actggagagc caggagccag cccacgcaca gccagcatcc
     1861 cctcagaatg tgctcccagt gaagagtctc ctaaagcgtg cttttcaaaa gtcggcatca
     1921 gtccggaata ttctcaggcc tgtcgggggt aaacgggtcg actctgcaga agtccagaag
     1981 gtttgcaaca tctgtgtcct ctaccagacc tcgctgacaa ctctcacaca gattcggctg
     2041 cagatactca caggtctcac ttaccttgat gacctgcttc ccaaactgtg ggcatttatc
     2101 tgtgagctcg ggccccacgg agggttaaag ctcttcttgg aatgcctgaa caatgacact
     2161 gaagagtcca agcaactctt ggccatgctg atgctgttct gtgactgttc gcggcacctc
     2221 atcacaatcc ttgatgacat tgaagtttat gaagaacaga tttcattcaa actggaagag
     2281 ctggtcacta tctcctcttt cctgaattct tttgtgttta agatgatctg ggatggaatt
     2341 gtagagaacg ccaagggtga gaccttggag ctgttccagt ctgtccacgg gtggcttatg
     2401 gtgctgtacg agcgggactg ccggcggcgc ttcacccccg aggaccactg gctgcgaaag
     2461 gatctcaaac ctagcgtgct cttccaagaa ctcgacaggg acagaaaacg ggcacagttg
     2521 atcctgcagt acatcccaca tgtcatccct cacaaaaaca gagttctact gtttcgaacc
     2581 atggttacca aggagaagga gaaactgggg ctggtggaaa ccagctctgc ctccccgcat
     2641 gtcactcaca tcaccatccg ccggtccagg atgctggagg acggctacga gcagcttagg
     2701 cagctctccc agcacgccat gaagggggtc atccgtgtga agtttgtcaa tgacctcggg
     2761 gtggacgaag cagggattga tcaagacggt gtttttaagg agttcttgga agagatcatc
     2821 aagagagttt ttgacccagc actcaatctg ttcaagacaa ccagtgggga tgagaggctg
     2881 tacccctcac ccacatccta catccatgag aattacctgc agctcttcga gtttgtgggg
     2941 aagatgctgg ggaaggctgt gtatgaggga attgtggtgg acgtgccatt tgcatccttc
     3001 ttcctgagcc aactgcttgg gcaccaccac agcgtcttct atagctcggt ggatgaactg
     3061 ccttctctgg actccgagtt ctataaaaac ctcacctcca tcaagcgcta tgatggggac
     3121 atcactgacc tgggcctgac gctgtcttac gacgaggacg tcatgggtca gcttgtttgc
     3181 catgaactga ttcctggagg gaagaccatt cctgttacaa atgaaaataa aattagctac
     3241 atccatctga tggcacattt tcgaatgcac actcaaataa aaaaccaaac agctgccctc
     3301 attagcggat tccgttccat tatcaaaccc gagtggatcc gaatgttctc aactcctgaa
     3361 ctgcagcgtc tcatctctgg cgacaatgct gagattgatc tggaagattt aaagaagcac
     3421 acagtctact acggtggttt ccatggaagt cacagagtca tcatctggct ctgggatatt
     3481 ctggcctccg acttcacacc ggatgagaga gctatgtttc tgaagttcgt gaccagctgc
     3541 tccagacccc cgctcctggg attcgcctac ctcaagcctc cattctccat ccgctgcgtg
     3601 gaggtgtcgg acgatcagca aggcaggcag ctggacccct cagagccaag tgaggagggc
     3661 cccacagttc tcacggcagg agaaccagcc agccccagag agactgccca cggactcagc
     3721 cctctctcgg cagccccttt ctctttcctt cctcagggaa gggtacctgg agtgggggtg
     3781 ggtacgtgct gtttttagtg gcgtctggcc tcaccagggc tccagatctg aggcagcatg
     3841 ggagaaagtg agagagtggg ctcaggaggc aggcaggcgc agactcgaat gctactccta
     3901 ccccagcagg ctgtgcacgt ccaggctcgc tgcttcattt cctcattggc caaaggagaa
     3961 ggaaagcctt cagggttacg gagctctgtg tgtctcaagc ctggcccact gtgggtgctc
     4021 aaatgagagt cctactcccc ataaaaaccc agtggccgcc tctgggtgta gctgcctctc
     4081 atgatgcagt ttgagcccgt gatgccacct tgtacaggaa gctacacagt cctcggcctc
     4141 catgcttaag ggaaagttgg cccaagtcat ggtctgccac cggccacagc accggtgagg
     4201 agggaggagt gcattcagaa atgtttgggc acctaacagt ttttacagca ttctactttt
     4261 tgtcaattgg ttaaccagta attcgctgtg aaccggaagg ccccatttcc aaaagcttac
     4321 ttagtgcagg aattctctgt gcaggcccca gggagaaggg gttccttctc tggaagccag
     4381 tcgtcttgtg tctggggctt gacctcgggt agtggtgcca gggcagcgcc ctgcactctg
     4441 cccagcatcc agggactggc cagatcccct ccctgggctc cctggccttg gcatcagcct
     4501 gggctcccaa actaggccct tcccaattca aggccacgat gtgtgccttc aggacaccgg
     4561 ggacactctg ggcagcgtcc tccggggctt cttcaccatc cgcaagcggg agccaggcgg
     4621 ccgcctgccc acctcctcca cctgcttcaa cctgctcaag ctgcccaact acagcaagaa
     4681 gagcgtcctc cgcgagaagc tgcgctacgc catcagcatg aacacgggct ttgaactctc
     4741 ctagctcctg tcccagccct gcctccaggg ctcctgggct gccagggacc ttcagctccc
     4801 agaggcagtg tggtcctggg aatgtgacca acatgccagg tgacattggc ccctagaccc
     4861 tctctatagc catgagactc cttgtggcct caagaaattt agacgcccac gacagcacta
     4921 cacagcatct ccaggtgatg cccaaggcac agggctgcag aaaataaacc tccagattcc
     4981 accaacacgg gtccattctt cctggtgatg gcagaggggc ttcttttagc tagtttgatc
     5041 ttttgggagt ctgtctttcc ttagccgtct gagtgagctg tgtatgaaca agtcccagga
     5101 gttccaagag tctagagtgg tttttgcagc atgggttgag tgtacaaagc ctactgtgcg
     5161 tgagatcctc tccttccgtt tctgaaatct cttactcagg taaggcctcg ccaagcctct
     5221 atgcacccca caaagtttct gcctccatgc cgtccacagc gcctcttccc agacagccag
     5281 gcccatctgc tgcccaggga agcgcaggcg cctgctaggg acgctatgga caccgtgagt
     5341 ccaaggcgct gctcctgcct tgaagccacg cgctccacgc cgcggccctc ccattttctg
     5401 cgtcctcagc gggctgagct gccagagagt cttcccggac ctattcccgt cctatgcatt
     5461 cacattggca tcctggtttg ggggaagaaa aacaacggcc cttagcagca gccccgtttc
     5521 cagaatgtgc tgcctgttcc ccaaagcctg cttgtcccgc ggaggacggc tgcctttgac
     5581 cctgcttatt tgtctcactg gttatctaat gaggaacaaa cactaaccta aggtacacat
     5641 cccatctggg cggtggcttc actcctgagt ctgcaaaatc ccaggaaact tgggtcttgc
     5701 tgcccatcct tcctcagcac agggaacccg gaagcccgtt gcactgacag aggctcacac
     5761 cctctgggtt ttttgttttt tttttaaact tcatttctct tccaacccat tgtgttcctc
     5821 tgccctcatt ctttaccttt gttgtaagaa ctttagctcc agggaactga ggcagaggcc
     5881 ctgtttgtgg tctgtgttga cagccaccca ccctctccca cctcatgctc ctgcacctgc
     5941 accaccaagg ttgatgccgg attcgaagcc aggaaggccc agtccctcct ctgctctcct
     6001 caaagacgca aaacattttc caacaagagc tgtcacagtg gcagcaaagc aggggccacc
     6061 cgtctccaca gtccttcaga gtttcagctg catcctggtg tcccacccag gtcgagcccc
     6121 caggcttctg gaaaagagtg tgtgctctac tttgatggaa acatggcaag gaatttaaag
     6181 acaggaatgt attaatatta ttgaaggtgt gttcgtaacc tctgattctg tggacttgcc
     6241 actttctcca aacgctcggt tcctttgaag atttcttctg aacgtgtgtg cgcacgctgg
     6301 gcgggttcgt gcatacatgc ggggacccca gactgtcagc acagggaaga tggatcccat
     6361 cctaattttt atcacctgaa ggttggaacc agtgagggac tgggagagag tgatttataa
     6421 gcaccaatat caacttcatg tggatttttg acaaggaggg gtagtttgta atttcattta
     6481 aattcttttc agcagctgga aatattgcac tatctgaaac actgaatctc cttttgtaac
     6541 tggtgttcac tgacaccttg atggctcttg atggctctaa aaagttgtag gattttttgt
     6601 ttttgtagct aacttatgga ttgagatgtg atcaaaggct ttattaaatt tgtacttcag
     6661 cata
//
