LOCUS       XM_047436517            5410 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens ubiquitin conjugating enzyme E2 O (UBE2O),
            transcript variant X4, mRNA.
ACCESSION   XM_047436517
VERSION     XM_047436517.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000017.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5410
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
     gene            1..5410
                     /gene="UBE2O"
                     /gene_synonym="E2-230K"
                     /note="ubiquitin conjugating enzyme E2 O; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 6 mRNAs, 37 ESTs, 934 long SRA reads, 6 Proteins, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 1 sample with support for all
                     annotated introns"
                     /db_xref="GeneID:63893"
                     /db_xref="HGNC:HGNC:29554"
                     /db_xref="MIM:617649"
     CDS             12..3923
                     /gene="UBE2O"
                     /gene_synonym="E2-230K"
                     /codon_start=1
                     /product="(E3-independent) E2 ubiquitin-conjugating enzyme
                     isoform X4"
                     /protein_id="XP_047292473.1"
                     /db_xref="GeneID:63893"
                     /db_xref="HGNC:HGNC:29554"
                     /db_xref="MIM:617649"
                     /translation="MADPAAPTPAAPAPAQAPAPAPEAVPAPAAAPVPAPAPASDSAS
                     GPSSDSGPEAGSQRLLFSHDLVSGRYRGSVHFGLVRLIHGEDSDSEGEEEGRGSSGCS
                     EAGGAGHEEGRASPLRRGYVRVQWYPEGVKQHVKETKAQQQQAAPLNAVSQDSNTSGN
                     STIMETGRSFCPILQLKLEDRSVVPRDVVRHMRSTDSQCGTVIDVNIDCAVKLIGTNC
                     IIYPVNSKDLQHIWPFMYGDYIAYDCWLGKVYDLKNQIILKLSNGARCSMNTEDGAKL
                     YDVCPHVSDSGLFFDDSYGFYPGQVLIGPAKIFSSVQWLSGVKPVLSTKSKFRVVVEE
                     VQVVELKVTWITKSFCPGGTDSVSPPPSVITQENLGRVKRLGCFDHAQRQLGERCLYV
                     FPAKVKRLLKKQVVRIMSCSPDTQCSRDHSMEDPDKKGESKTKSEAESASPEETPDGS
                     ASPVEMQDEGAEEPHEAGEQLPPFLLKEGRDDRLHSAEQDADDEAADDTDDTSSVTSS
                     ASSTTSSQSGSGTSRKKSIPLSIKNLKRKHKRKKNKITRDFKPGDRVAVEVVTTMTSA
                     DVMWQDGSVECNIRSNDLFPVHHLDNNEFCPGDFVVDKRVQSCPDPAVYGVVQSGDHI
                     GRTCMVKWFKLRPSGDDVELIGEEEDVSVYDIADHPDFRFRTTDIVIRIGNTEDGAPH
                     KEDEPSVGQVARVDVSSKVEVVWADNSKTIILPQHLYNIESEIEESDYDSVEGSTSGA
                     SSDEWEDDSDSWETDNGLVEDEHPKIEEPPIPPLEQPVAPEDKGVVISEEAATAAVQG
                     AVAMAAPMAGLMEKAGKDGPPKSFRELKEAIKILESLKNMTVEQLLTGSPTSPTVEPE
                     KPTREKKFLDDIKKLQENLKKTLDNVAIVEEEKMEAVPDVERKEDKPEGQSPVKAEWP
                     SETPVLCQQCGGKPGVTFTSAKGEVFSVLEFAPSNHSFKKIEFQPPEAKKFFSTVRKE
                     MALLATSLPEGIMVKTFEDRMDLFSALIKGPTRTPYEDGLYLFDIQLPNIYPAVPPHF
                     CYLSQCSGRLNPNLYDNGKVCVSLLGTWIGKGTERWTSKSSLLQVLISIQGLILVNEP
                     YYNEAGFDSDRGLQEGYENSRCYNEMALIRVVQSMTQLVRRPPEVFEQEIRQHFSTGG
                     WRLVNRIESWLETHALLEKAQALPNGVPKASSSPEPPAVAELSDSGQQEPEDGGPAPG
                     EASQGSDSEGGAQGLASASRDHTDQTSETAPDASVPPSVKPKKRRKSYRSFLPEKSGY
                     PDIGFPLFPLSKGFIKSIRGVLTQFRAALLEAGMPECTEDK"
ORIGIN      
        1 gcagagcagt tatggcggat cccgcagccc ccacgcccgc agctcccgct ccagcccagg
       61 ccccggctcc agccccggag gcagtcccgg ccccagccgc agcccccgtc ccggcgccgg
      121 cgcccgcctc ggactcggcc tccgggccgt cctcggactc cggcccagaa gccggctcgc
      181 agcgcctgct gttttctcac gacctggtgt cgggccgtta ccgtggctcc gtgcacttcg
      241 ggctggtgcg cctcatccac ggcgaggact cggactcgga gggcgaggag gagggccgcg
      301 ggagctcggg gtgctccgag gccgggggcg cgggccacga ggagggccgg gccagccccc
      361 tgcgccgcgg ctacgtgcgc gtccagtggt acccggaggg cgtcaagcag catgtgaagg
      421 agaccaaggc acaacagcag caagcagctc ctctaaatgc agtgagccag gactcaaata
      481 ccagcggaaa cagcaccatc atggagactg ggaggagttt ctgcccaatt ctgcagctga
      541 aactagagga ccgttctgtg gtgccccgag atgtggtccg gcacatgcga tccaccgaca
      601 gtcagtgtgg cacggtgatc gacgtcaaca tcgactgtgc cgtcaagctc atcggcacca
      661 actgcatcat ctatcccgtc aacagcaagg acctgcagca catctggccc ttcatgtatg
      721 gggactacat tgcctatgac tgctggctgg ggaaggtcta cgacttgaag aaccagatca
      781 tcctgaagct atccaacggc gccaggtgct ccatgaacac ggaagatggc gccaagctct
      841 acgacgtctg cccgcacgtc agcgactcgg gtctcttctt cgatgattcc tatggcttct
      901 acccaggcca ggtgctcatt ggccctgcca agatcttctc cagcgtccag tggctgtcag
      961 gtgtcaagcc cgtgctcagc accaagagca agttccgagt ggtggtggaa gaggtgcagg
     1021 ttgtagagtt gaaagttaca tggattacca agagtttctg tccagggggc acggacagcg
     1081 tcagcccccc accctctgtc atcacccagg aaaacctagg cagggtgaag cgtctcggat
     1141 gctttgacca tgctcagcgg cagcttgggg agcgctgtct gtatgtcttc ccagccaagg
     1201 tgaagcgcct gttgaagaag caggttgtgc ggatcatgtc atgctcccca gacacccagt
     1261 gttcccggga ccattccatg gaagacccag acaagaaggg ggaatccaaa accaagagcg
     1321 aagcggagtc tgccagccct gaggagacgc ccgatggctc tgccagtcca gtggagatgc
     1381 aggacgaggg tgcagaggag ccccacgagg caggagagca gctgccccca ttcctgctaa
     1441 aagaaggcag agatgacagg ctgcactcgg cagagcagga cgcagatgat gaggctgctg
     1501 atgacacgga cgacaccagt tcggtgacct cctctgccag ctccaccact tcctcccaga
     1561 gcggcagcgg cacgagtcgc aaaaagagca tccccttgtc catcaagaac ttaaagcgca
     1621 aacacaagag gaagaagaat aaaatcactc gagacttcaa gccaggggac agggtggcag
     1681 tggaggtggt gaccacgatg acctcagccg acgtgatgtg gcaggatggc tccgtggaat
     1741 gcaacatccg ctccaacgac ctcttccctg tgcaccacct ggacaacaac gagttctgcc
     1801 ctggagactt cgtggtagat aagcgagtcc agagctgtcc agaccctgct gtctacggtg
     1861 tggtacagtc tggggaccac atcggccgta cctgcatggt gaagtggttc aagctgaggc
     1921 cgagtgggga cgacgtggag ctgattggag aagaggaaga tgtgagtgtt tacgacattg
     1981 ctgaccaccc tgactttagg ttccgtacaa ctgacatcgt catccgcatc ggcaatactg
     2041 aggatggggc tcctcacaag gaggatgagc catcggtggg ccaggtggcc cgtgtggacg
     2101 tcagcagcaa ggtggaggtg gtgtgggctg acaactcaaa gaccatcatc ctgccccagc
     2161 acttgtacaa catagagtct gagattgagg agtcagacta cgattcggta gaaggcagca
     2221 ccagcggggc atcctcggat gaatgggaag atgatagtga cagctgggag acggacaatg
     2281 ggctggtgga ggacgagcac cccaagatag aggagccccc catcccaccc ctggagcagc
     2341 cggtggcccc tgaggacaag ggagtggtga tcagtgaaga ggcagccaca gctgccgtcc
     2401 agggggctgt ggccatggct gcccccatgg ccgggctgat ggagaaggct ggcaaggacg
     2461 ggccacccaa gagcttccgg gagttgaaag aggccatcaa gatcctggag agcctcaaga
     2521 acatgactgt ggagcagctg ctgacgggct cgcccacctc tccgactgtg gagcctgaga
     2581 agccaactcg ggagaagaag tttctggatg acatcaagaa gctacaggaa aacctcaaga
     2641 agaccctgga caatgtggcc attgtagagg aggagaagat ggaagcagtg cccgacgtag
     2701 agcgcaagga ggacaagccc gaggggcagt cacctgtgaa ggctgagtgg cccagcgaaa
     2761 ccccggtgct gtgccagcag tgtggcggca agcctggcgt caccttcacc agcgccaagg
     2821 gcgaggtctt ctccgtactg gagtttgcac cctcaaatca ttcttttaag aaaattgagt
     2881 tccagcctcc agaagccaag aagttcttca gcacagtgcg gaaggagatg gcgctgctgg
     2941 ctacctcact gcctgagggc atcatggtca agacttttga agatagaatg gacctcttct
     3001 cagctctcat caagggcccc actcgaaccc cctacgagga tggcctctac ttgtttgaca
     3061 tccagctccc caacatctac ccagccgtgc ccccccactt ctgctacctc tcccaatgca
     3121 gtggccgcct gaaccccaac ctgtatgaca atgggaaggt gtgtgtcagc ctcctgggca
     3181 cctggattgg aaaggggaca gagaggtgga caagcaagtc cagccttctc caggtgctca
     3241 tctccatcca aggtctgatc ctggtaaatg aaccatacta caacgaagcc ggcttcgaca
     3301 gtgaccgagg cctgcaggaa ggctatgaaa acagtcgctg ttacaatgag atggcgctga
     3361 tccgcgtggt gcagtccatg acccagctgg tgcggcggcc ccccgaggtc tttgagcagg
     3421 agatcaggca acactttagc actggtggct ggcggctggt gaaccgtatc gagtcctggc
     3481 tggaaaccca tgccctgctg gagaaggccc aggcactgcc caacggggtg cccaaggcca
     3541 gcagctcgcc agagccccca gctgtagccg agctgtcaga ctccggccaa caagaacctg
     3601 aggatggagg gccagcccca ggagaggcct cccagggctc agactcagag ggcggtgccc
     3661 agggcctggc ctcagctagc agggaccaca cagaccagac ttcggagacc gcaccagacg
     3721 catcggtgcc acccagtgtg aaaccaaaga agcggagaaa gagctaccgg agcttcttac
     3781 ctgagaagag tggctaccct gacatcggct tccccctctt cccactttcc aagggtttca
     3841 tcaagagcat ccggggtgtc ctgacgcagt tccgggctgc cctgctagag gcaggcatgc
     3901 cggagtgcac agaggacaag tagctgccag gcacagagga aagagcatca ccgtgggaga
     3961 ggccagccgc cgcctgctca ctcccccccg gaatcacccc tcttcccatg cccctctgtc
     4021 cccactgcaa acccactgcc ctcttctccc caaggtgagt ttgatgctga agtgcaagaa
     4081 gtgtgttgag atgctgccgt ttctattttg aagcgagctt tcaacaggcg ggtcccctgt
     4141 ggcaaagaaa atcggaaccc tgttgccgat tttccatttg tcaccccagc agaatgtccg
     4201 gcacttgctc ccttgctgcc ccttctcagg tcagaggcgg gtgttccagg gcctgccgcg
     4261 gggctctctg ggccggttcc ctgcagaccc gcaggagagc acatgtgcct tgcatgaagt
     4321 gtgggttgcg ccaacaattc ccctggtccc tttcaacctg tttagttcaa ctcaagcctc
     4381 cctgtgtccc agaccctcct gctgccacca ccacccaggt cctccctagt cctccagcgt
     4441 caacactatc ccttgggagt tgtagctgct gtcactgact cccggctata catggcctgt
     4501 cgaccacgtt atagccctca ggcctgttga acttgctctc taagagaggt tgggaccagg
     4561 ctaggttccg ggtgacgccc aggagaggtg gtggccttca cacatgcaca tggagttgag
     4621 gaccagggag ctgcagggaa agcaacagct ataggtgcct tgctcttctg tcggaggctg
     4681 ctgggggcaa gagcagctgc acaaggccag ggcaagtgct agggcccctc ccccatcaca
     4741 tggtcacact gggacaggcg tgcagctcac tgaactccaa gcgagccagc cctctcttgg
     4801 actagaaggc ctactgtcag cccttcgctt acaaactgca ggctcaatcc gaaggggacg
     4861 gccggcgggg gctctcctag tgcccagaga caggcccaga ggtttacaag ttttctaagc
     4921 ttttgataat gtgaagctcc aggccgagag gatgctgttg agcacattgc agctatgtaa
     4981 tttttggtgt atgtatgtaa tatttaaggt tggaaaaaaa actcaaaagc aaagatatta
     5041 actcttatta gaaaaaaaga caaaaaaaaa gccaaagcat gatgcgtctt gtcagcctta
     5101 agtgggctcc acacctgtgc tgtgctgtga ccgcccagcc agcagagctg cgggaggatg
     5161 gagccggacc acacaccgtg gcatttggaa ccgagtcggt atcttgtttg agaaacaccc
     5221 ggagtgactg gtggggctgt gcttcccagt gcattgtaca tgtggagatg tgaatgccta
     5281 ctgcttacga tatctgtata aagtgctgtg tgattaaact tttttttact tgcatttttt
     5341 tttttttttt tttttgtgtt ggctcattag caagacaagg tgacaccatt aaacctccct
     5401 ctgccattca
//
