LOCUS       NM_001355247            2731 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens ubiquitin conjugating enzyme E2 L5 (UBE2L5), mRNA.
ACCESSION   NM_001355247
VERSION     NM_001355247.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2731)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL161893.24.
            
            On May 17, 2019 this sequence version replaced NM_001355247.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803614.13680.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000635918.2/ ENSP00000490225.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-185               AL161893.24        41812-41996
            186-279             AL161893.24        44127-44220
            280-333             AL161893.24        46044-46097
            334-2731            AL161893.24        46680-49077
FEATURES             Location/Qualifiers
     source          1..2731
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="13"
                     /map="13q12.3"
     gene            1..2731
                     /gene="UBE2L5"
                     /gene_synonym="UBCH7N2; UBE2L5P"
                     /note="ubiquitin conjugating enzyme E2 L5"
                     /db_xref="GeneID:171222"
                     /db_xref="HGNC:HGNC:13477"
     exon            1..185
                     /gene="UBE2L5"
                     /gene_synonym="UBCH7N2; UBE2L5P"
                     /inference="alignment:Splign:2.1.0"
     exon            186..279
                     /gene="UBE2L5"
                     /gene_synonym="UBCH7N2; UBE2L5P"
                     /inference="alignment:Splign:2.1.0"
     exon            280..333
                     /gene="UBE2L5"
                     /gene_synonym="UBCH7N2; UBE2L5P"
                     /inference="alignment:Splign:2.1.0"
     exon            334..2731
                     /gene="UBE2L5"
                     /gene_synonym="UBCH7N2; UBE2L5P"
                     /inference="alignment:Splign:2.1.0"
     CDS             964..1428
                     /gene="UBE2L5"
                     /gene_synonym="UBCH7N2; UBE2L5P"
                     /EC_number="2.3.2.23"
                     /note="ubiquitin-protein ligase L5"
                     /codon_start=1
                     /product="ubiquitin-conjugating enzyme E2 L5"
                     /protein_id="NP_001342176.1"
                     /db_xref="CCDS:CCDS86346.1"
                     /db_xref="GeneID:171222"
                     /db_xref="HGNC:HGNC:13477"
                     /translation="MAASRRLMKELEEIRKCGMENFRNIQVDEANLLTWQGLIVPDNP
                     PYNKGAFRIEINFPAEYPFKPPRITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTD
                     QVIQSLIALVNDPQPEHPLRADLAEEYSNDRKKFCKNAEEFTKKYGEKRPVD"
     regulatory      2710..2715
                     /regulatory_class="polyA_signal_sequence"
                     /gene="UBE2L5"
                     /gene_synonym="UBCH7N2; UBE2L5P"
                     /note="hexamer: ATTAAA"
     polyA_site      2731
                     /gene="UBE2L5"
                     /gene_synonym="UBCH7N2; UBE2L5P"
                     /note="major polyA site"
ORIGIN      
        1 actccgctcc gtgaggcttc cgggagaggg aaagctgttc tcctttgatg ctctttggtt
       61 ttacagtgga aaactacaat taaaaaaaca tagccgtgaa aataaatgag attagaacct
      121 gctggcttca cttcctggag gctttttgtt gtgtcttgaa actaggatct ttgcgggtca
      181 tcccttttct gagtgcagtc aatcatagct cactgcagcc tcgacctcct gggctcagtg
      241 atcttcccgg tccagcctcc tgagcagcta ggattacagg ctttgatcaa aatcaaccat
      301 tcctttccaa aattcagaag cttccacaac aagaacatga actggattaa tagaaatttc
      361 tcagaaaaaa atattcaaac accaaggatc tcactttgtg ctgtgaaatg caagatgagc
      421 aatctgatct ggacatacca gccttcagtc aggcaacagg tgaatatgca ggtagaatta
      481 taatgtgtaa agccgggtgc agtggctcac gtctataatc tgagcacttt gggagactaa
      541 cgcgggcgga tcacttgagg tcaggagttc gagactagcc aggccaacat ggtgaaacct
      601 cgtctctact aaaaatacaa aaaaaagtta gctgtgcatg gtggcacgtg cctgtaatca
      661 cagccacttg ggaggccgag gcgagaggat ggcttgaacc cgggaggctg aggttgcaat
      721 gagcagagat ggtgccactg cactccagcc tgggcaacag agagagactc tggctaaaaa
      781 aaaaaaaaat tataatgtat aggattgtgg atgatcactc taaccaacca gtgggcaagt
      841 tgctttgctc agcgtaagtt caaactgcca catcagaacg ttatttgagt gtatacatac
      901 acaaccatta aaagtggccg ttaccacgat gcattctggg aaagaagcag caccaaatcc
      961 aagatggcgg ccagcaggag gctgatgaag gagcttgaag aaatccgcaa atgtggaatg
     1021 gaaaacttcc gtaacatcca ggttgatgaa gctaatttat tgacttggca agggcttatt
     1081 gttcctgaca accctccgta taataagggg gccttcagaa tcgaaatcaa ctttccagca
     1141 gagtacccat tcaaaccacc gaggatcaca tttaaaacaa agatctatca cccgaacatc
     1201 gacgaaaagg ggcaggtctg tctgccagta attagtgctg aaaactggaa gccagcaacc
     1261 aaaaccgacc aagtaatcca gtccctcata gcactggtga atgacccgca gcccgagcac
     1321 ccgcttcggg ctgacctagc tgaagaatac tctaacgacc gtaaaaaatt ctgtaagaat
     1381 gctgaagagt ttacaaagaa atatggggaa aagcgacctg tggactaaaa tgtgccacga
     1441 ttggttccag caagtgtgag cagagacccc gtgcagtaca ttcagacacc ccgcaaagca
     1501 ggactctgtg gaaattgata cgtgccaccg tctggcgttc gcttgcagca gttactaact
     1561 ttctacagtt ttcttaatta aaagtggtct aggtaacctg taaagaaagg attaaaaatt
     1621 taagatgttc ttaaaaaaaa aaaaagtggc cattaataga cggaactata cactggacta
     1681 gttgttgttt taaaaacata aaatctggct accctaacgg gataagagtt cagacatcag
     1741 gatgttgaca cagtgtccta ccagaaccca gggtttactt agagaacata aaagaaaaga
     1801 gattgtatgc tatattcctt gctttttttt tttttttttt ggtggatgta gataggagat
     1861 gggatgagag tggccacagg aattcgatga gtcgtaggaa atccattttt gttttaattg
     1921 atgtttcccg ttgaactgac atttagattg aaatacctgc gagccgggtt tggtggctca
     1981 cacctgtaat gctatcactt tgggaagctg aggtgggtgg atcacctgag gtcaggagtt
     2041 cgagaccagc ctggccaacg tggtgaaacc ccatctctat taaaaataaa ataaataaac
     2101 aaataaaagt agccgggcgt ggtggcagac tcctgtaatc ccagctactc aggaggctga
     2161 ggcaggataa tcgtttggac cctggaggca gaggctgcag tgagcccaga ttgcgccatt
     2221 gcactccagc ctgggcaaca agagcaaaac tctgtccccc ccccacaaaa aaaaattgat
     2281 tgaaatacct ggaattcaca ccataattgg ggtgtcttta ggctgaaatg gagacaacag
     2341 aaggtgaggt ggcttggact caggtggcat tggtaaagga aatgaaacgc atgcaaattt
     2401 cacagacaaa agagtagctt tgccacctct cattttggct gggctgctct gaggtgctgc
     2461 atcttttata gtgtctaggc tctcatcctt aatgacattt tcatattctc catcccccat
     2521 cccccaccgc ctctccagta aggacttttt gacaagctgc acttccctgc tttagtaatt
     2581 ggtgataaga tttgtcctgt agaacatata catagaggat tgttcactct cctcctttta
     2641 tgaaataatt tttagaaatt gagctgttaa aggttgtgtt tgcacatgtt ttttggaaca
     2701 agaactttaa ttaaaggatc aaaaagccca a
//
