LOCUS       NM_001370062            4275 bp    mRNA    linear   PRI 17-MAR-2024
DEFINITION  Homo sapiens ubiquitin associated protein 2 (UBAP2), transcript
            variant 9, mRNA.
ACCESSION   NM_001370062
VERSION     NM_001370062.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4275)
  AUTHORS   Lv,Z., Shi,Y., Wu,H., Cao,K., Liu,X. and Wang,C.
  TITLE     Novel Circular RNA CircUBAP2 Drives Tumor Progression by Regulating
            the miR-143/TFAP2B Axis in Prostate Cancer
  JOURNAL   Protein Pept Lett 31 (1), 61-73 (2024)
   PUBMED   37962045
  REMARK    GeneRIF: Novel Circular RNA CircUBAP2 Drives Tumor Progression by
            Regulating the miR-143/TFAP2B Axis in Prostate Cancer.
REFERENCE   2  (bases 1 to 4275)
  AUTHORS   Chou,M.C., Wang,Y.H., Chen,F.Y., Kung,C.Y., Wu,K.P., Kuo,J.C.,
            Chan,S.J., Cheng,M.L., Lin,C.Y., Chou,Y.C., Ho,M.C., Firestine,S.,
            Huang,J.R. and Chen,R.H.
  TITLE     PAICS ubiquitination recruits UBAP2 to trigger phase separation for
            purinosome assembly
  JOURNAL   Mol Cell 83 (22), 4123-4140 (2023)
   PUBMED   37848033
  REMARK    GeneRIF: PAICS ubiquitination recruits UBAP2 to trigger phase
            separation for purinosome assembly.
REFERENCE   3  (bases 1 to 4275)
  AUTHORS   Herlihy,A.E., Boeing,S., Weems,J.C., Walker,J.,
            Dirac-Svejstrup,A.B., Lehner,M.H., Conaway,R.C., Conaway,J.W. and
            Svejstrup,J.Q.
  TITLE     UBAP2/UBAP2L regulate UV-induced ubiquitylation of RNA polymerase
            II and are the human orthologues of yeast Def1
  JOURNAL   DNA Repair (Amst) 115, 103343 (2022)
   PUBMED   35633597
  REMARK    GeneRIF: UBAP2/UBAP2L regulate UV-induced ubiquitylation of RNA
            polymerase II and are the human orthologues of yeast Def1.
REFERENCE   4  (bases 1 to 4275)
  AUTHORS   Benz,C., Ali,M., Krystkowiak,I., Simonetti,L., Sayadi,A.,
            Mihalic,F., Kliche,J., Andersson,E., Jemth,P., Davey,N.E. and
            Ivarsson,Y.
  TITLE     Proteome-scale mapping of binding sites in the unstructured regions
            of the human proteome
  JOURNAL   Mol Syst Biol 18 (1), e10584 (2022)
   PUBMED   35044719
REFERENCE   5  (bases 1 to 4275)
  AUTHORS   Xiong,H., Yu,J., Jia,G., Su,Y., Zhang,J., Xu,Q. and Sun,X.
  TITLE     Emerging roles of circUBAP2 targeting miR-370-3p in proliferation,
            apoptosis, and invasion of papillary thyroid cancer cells
  JOURNAL   Hum Cell 34 (6), 1866-1877 (2021)
   PUBMED   34346032
  REMARK    GeneRIF: Emerging roles of circUBAP2 targeting miR-370-3p in
            proliferation, apoptosis, and invasion of papillary thyroid cancer
            cells.
REFERENCE   6  (bases 1 to 4275)
  AUTHORS   Zuo,L., Saba,L., Wang,K., Zhang,X., Krystal,J.H., Tabakoff,B. and
            Luo,X.
  TITLE     Exome-wide association study of replicable nonsynonymous variants
            conferring risk for alcohol dependence
  JOURNAL   J Stud Alcohol Drugs 74 (4), 622-625 (2013)
   PUBMED   23739027
  REMARK    GeneRIF: By incorporating the information from bioinformatics and
            RNA expression analyses, we identified at least two of the most
            promising risk genes for alcohol dependence: APOER2 and UBAP2
REFERENCE   7  (bases 1 to 4275)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   8  (bases 1 to 4275)
  AUTHORS   Venturelli,E., Villa,C., Fenoglio,C., Clerici,F., Marcone,A.,
            Benussi,L., Ghidoni,R., Gallone,S., Scalabrini,D., Cortini,F.,
            Fumagalli,G., Cappa,S., Binetti,G., Franceschi,M., Rainero,I.,
            Giordana,M.T., Mariani,C., Bresolin,N., Scarpini,E. and
            Galimberti,D.
  TITLE     Is KIF24 a genetic risk factor for Frontotemporal Lobar
            Degeneration?
  JOURNAL   Neurosci Lett 482 (3), 240-244 (2010)
   PUBMED   20670673
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   9  (bases 1 to 4275)
  AUTHORS   Dieci,G., Preti,M. and Montanini,B.
  TITLE     Eukaryotic snoRNAs: a paradigm for gene expression flexibility
  JOURNAL   Genomics 94 (2), 83-88 (2009)
   PUBMED   19446021
  REMARK    GeneRIF: UBAP2 serves as a host gene for snoRNAs
            Review article
REFERENCE   10 (bases 1 to 4275)
  AUTHORS   Hofmann,K. and Bucher,P.
  TITLE     The UBA domain: a sequence motif present in multiple enzyme classes
            of the ubiquitination pathway
  JOURNAL   Trends Biochem Sci 21 (5), 172-173 (1996)
   PUBMED   8871400
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL354989.13 and AL139113.21.
            
            On Nov 30, 2019 this sequence version replaced NM_001370062.1.
            
            Summary: The protein encoded by this gene contains a UBA (ubiquitin
            associated) domain, which is characteristic of proteins that
            function in the ubiquitination pathway. This gene may show
            increased expression in the adrenal gland and lymphatic tissues.
            Alternative splicing results in multiple transcript variants.
            [provided by RefSeq, Sep 2013].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR11853566.27546.1,
                                           SRR11853565.28437.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000379238.7/ ENSP00000368540.2
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-63                AL354989.13        60848-60910         c
            64-203              AL354989.13        29073-29212         c
            204-281             AL354989.13        10810-10887         c
            282-392             AL354989.13        8246-8356           c
            393-546             AL139113.21        192276-192429       c
            547-624             AL139113.21        190063-190140       c
            625-679             AL139113.21        176486-176540       c
            680-783             AL139113.21        174954-175057       c
            784-849             AL139113.21        167029-167094       c
            850-902             AL139113.21        164129-164181       c
            903-970             AL139113.21        159382-159449       c
            971-1160            AL139113.21        156588-156777       c
            1161-1374           AL139113.21        151677-151890       c
            1375-1649           AL139113.21        147668-147942       c
            1650-1819           AL139113.21        146723-146892       c
            1820-2033           AL139113.21        144952-145165       c
            2034-2073           AL139113.21        139142-139181       c
            2074-2212           AL139113.21        136793-136931       c
            2213-2279           AL139113.21        135865-135931       c
            2280-2475           AL139113.21        131100-131295       c
            2476-2567           AL139113.21        130292-130383       c
            2568-2615           AL139113.21        129920-129967       c
            2616-2694           AL139113.21        127509-127587       c
            2695-2900           AL139113.21        127098-127303       c
            2901-3000           AL139113.21        126682-126781       c
            3001-3108           AL139113.21        126489-126596       c
            3109-3176           AL139113.21        126269-126336       c
            3177-3368           AL139113.21        125990-126181       c
            3369-4275           AL139113.21        124996-125902       c
FEATURES             Location/Qualifiers
     source          1..4275
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9p13.3"
     gene            1..4275
                     /gene="UBAP2"
                     /gene_synonym="UBAP-2"
                     /note="ubiquitin associated protein 2"
                     /db_xref="GeneID:55833"
                     /db_xref="HGNC:HGNC:14185"
     exon            1..63
                     /gene="UBAP2"
                     /gene_synonym="UBAP-2"
                     /inference="alignment:Splign:2.1.0"
     exon            64..203
                     /gene="UBAP2"
                     /gene_synonym="UBAP-2"
                     /inference="alignment:Splign:2.1.0"
     CDS             105..3464
                     /gene="UBAP2"
                     /gene_synonym="UBAP-2"
                     /note="isoform 1 is encoded by transcript variant 9;
                     AD-012 protein; RNA polymerase II degradation factor
                     UBAP2"
                     /codon_start=1
                     /product="ubiquitin-associated protein 2 isoform 1"
                     /protein_id="NP_001356991.2"
                     /db_xref="CCDS:CCDS6547.1"
                     /db_xref="GeneID:55833"
                     /db_xref="HGNC:HGNC:14185"
                     /translation="MMTSVSSDHCRGAREKPQISAAQSTQPQKQVVQATAEQMRLAQV
                     IFDKNDSDFEAKVKQLMEVTGKNQDECIVALHDCNGDVNKAINILLEGNSDTTSWETV
                     GCKKKNFAKENSENKENREKKSEKESSRGRGNNNRKGRGGNRGREFRGEENGIDCNQV
                     DKPSDRGKRARGRGFGRGRGRGAGRFSTQGMGTFNPADYSDSTSTDVCGTKLVVWEAA
                     QNGADEGTELASNTHNIAQDLSNKSSYGLKGAWKNSVEEWTTEDWTEDLSETKVFTAS
                     SAPAENHILPGQSIDLVALLQKPVPHSQASEANSFETSQQQGFGQALVFTNSQHNNQM
                     APGTGSSTAVNSCSPQSLSSVLGSGFGELAPPKMANITSSQILDQLKAPSLGQFTTTP
                     STQQNSTSHPTTTTSWDLKPPTSQSSVLSHLDFKSQPEPSPVLSQLSQRQQHQSQAVT
                     VPPPGLESFPSQAKLRESTPGDSPSTVNKLLQLPSTTIENISVSVHQPQPKHIKLAKR
                     RIPPASKIPASAVEMPGSADVTGLNVQFGALEFGSEPSLSEFGSAPSSENSNQIPISL
                     YSKSLSEPLNTSLSMTSAVQNSTYTTSVITSCSLTSSSLNSASPVAMSSSYDQSSVHN
                     RIPYQSPVSSSESAPGTIMNGHGGGRSQQTLDTPKTTGPPSALPSVSSLPSTTSCTAL
                     LPSTSQHTGDLTSSPLSQLSSSLSSHQSSLSAHAALSSSTSHTHASVESASSHQSSAT
                     FSTAATSVSSSASSGASLSSSMNTANSLCLGGTPASASSSSSRAAPLVTSGKAPPNLP
                     QGVPPLLHNQYLVGPGGLLPAYPIYGYDELQMLQSRLPVDYYGIPFAAPTALASRDGS
                     LANNPYPGDVTKFGRGDSASPAPATTPAQPQQSQSQTHHTAQQPFVNPALPPGYSYTG
                     LPYYTGMPSAFQYGPTMFVPPASAKQHGVNLSTPTPPFQQASGYGQHGYSTGYDDLTQ
                     GTAAGDYSKGGYAGSSQAPNKSAGSGPGKGVSVSSSTTGLPDMTGSVYNKTQTFDKQG
                     FHAGTPPPFSLPSVLGSTGPLASGAAPGYAPPPFLHILPAHQQPHSQLLHHHLPQDAQ
                     SGSGQRSQPSSLQPKSQASKPAYGNSPYWTN"
     exon            204..281
                     /gene="UBAP2"
                     /gene_synonym="UBAP-2"
                     /inference="alignment:Splign:2.1.0"
     exon            282..392
                     /gene="UBAP2"
                     /gene_synonym="UBAP-2"
                     /inference="alignment:Splign:2.1.0"
     exon            393..546
                     /gene="UBAP2"
                     /gene_synonym="UBAP-2"
                     /inference="alignment:Splign:2.1.0"
     exon            547..624
                     /gene="UBAP2"
                     /gene_synonym="UBAP-2"
                     /inference="alignment:Splign:2.1.0"
     exon            625..679
                     /gene="UBAP2"
                     /gene_synonym="UBAP-2"
                     /inference="alignment:Splign:2.1.0"
     exon            680..783
                     /gene="UBAP2"
                     /gene_synonym="UBAP-2"
                     /inference="alignment:Splign:2.1.0"
     exon            784..849
                     /gene="UBAP2"
                     /gene_synonym="UBAP-2"
                     /inference="alignment:Splign:2.1.0"
     exon            850..902
                     /gene="UBAP2"
                     /gene_synonym="UBAP-2"
                     /inference="alignment:Splign:2.1.0"
     exon            903..970
                     /gene="UBAP2"
                     /gene_synonym="UBAP-2"
                     /inference="alignment:Splign:2.1.0"
     exon            971..1160
                     /gene="UBAP2"
                     /gene_synonym="UBAP-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1161..1374
                     /gene="UBAP2"
                     /gene_synonym="UBAP-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1375..1649
                     /gene="UBAP2"
                     /gene_synonym="UBAP-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1650..1819
                     /gene="UBAP2"
                     /gene_synonym="UBAP-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1820..2033
                     /gene="UBAP2"
                     /gene_synonym="UBAP-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2034..2073
                     /gene="UBAP2"
                     /gene_synonym="UBAP-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2074..2212
                     /gene="UBAP2"
                     /gene_synonym="UBAP-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2213..2279
                     /gene="UBAP2"
                     /gene_synonym="UBAP-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2280..2475
                     /gene="UBAP2"
                     /gene_synonym="UBAP-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2476..2567
                     /gene="UBAP2"
                     /gene_synonym="UBAP-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2568..2615
                     /gene="UBAP2"
                     /gene_synonym="UBAP-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2616..2694
                     /gene="UBAP2"
                     /gene_synonym="UBAP-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2695..2900
                     /gene="UBAP2"
                     /gene_synonym="UBAP-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2901..3000
                     /gene="UBAP2"
                     /gene_synonym="UBAP-2"
                     /inference="alignment:Splign:2.1.0"
     exon            3001..3108
                     /gene="UBAP2"
                     /gene_synonym="UBAP-2"
                     /inference="alignment:Splign:2.1.0"
     exon            3109..3176
                     /gene="UBAP2"
                     /gene_synonym="UBAP-2"
                     /inference="alignment:Splign:2.1.0"
     exon            3177..3368
                     /gene="UBAP2"
                     /gene_synonym="UBAP-2"
                     /inference="alignment:Splign:2.1.0"
     exon            3369..4275
                     /gene="UBAP2"
                     /gene_synonym="UBAP-2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4256..4261
                     /regulatory_class="polyA_signal_sequence"
                     /gene="UBAP2"
                     /gene_synonym="UBAP-2"
                     /note="hexamer: AATAAA"
     polyA_site      4275
                     /gene="UBAP2"
                     /gene_synonym="UBAP-2"
                     /note="major polyA site"
ORIGIN      
        1 acattggcag gtaacgagcg gcggcggcgg cagcgggtct tgggtcctcc gagagcagca
       61 gcgattttct attttgtaca tacattattt tgtatatact gtatatgatg acttcagtga
      121 gcagtgacca ttgtcgaggt gctcgggaaa aaccacagat ttcagcagca caatcaacgc
      181 aaccacagaa acaagtggta caggcaacag ctgaacagat gcgtctcgct caagtgatct
      241 ttgataagaa tgattcagat tttgaagcta aagttaagca gcttatggaa gtgacaggga
      301 aaaatcagga tgaatgcata gtggccctac atgattgtaa tggagatgtg aacaaagcta
      361 tcaatatatt gctggaaggg aattcagaca caacttcatg ggagactgta gggtgtaaga
      421 aaaagaattt tgcaaaagaa aattcagaaa acaaagagaa tagagagaag aaaagcgaga
      481 aagaatcgag tcgtggacgt ggaaacaaca accggaaagg aagaggcggc aatcgtggca
      541 gagaatttag aggtgaagaa aatggaattg attgcaatca agtggacaaa ccttcagatc
      601 gtggcaagcg agcccggggt agaggatttg gacgtggcag agggagaggg gcaggaaggt
      661 tctcaaccca aggcatgggg acatttaatc ctgcagacta ttcagattct acatctacag
      721 atgtgtgtgg gacaaagcta gtagtttggg aagctgctca gaatggtgca gatgagggaa
      781 ctgaactggc atcaaatact cacaacatag ctcaggatct gtcaaacaaa agttcttatg
      841 gactcaaagg ggcttggaag aattctgtgg aagagtggac aacagaagac tggactgaag
      901 atctttctga aacaaaggtc ttcactgcct catctgctcc agcagagaat cacatcttac
      961 ctgggcaaag cattgatctg gtagccttgc tccagaagcc tgttcctcac agtcaagcct
     1021 cagaagccaa ctcctttgaa acttcccaac agcagggctt tggccaagcc cttgtcttca
     1081 caaattcgca acacaacaat cagatggcac cagggactgg cagctccact gccgtcaact
     1141 cctgttctcc tcagagcctg tcatccgtcc ttggctcagg atttggagag cttgcaccac
     1201 caaaaatggc aaacatcacc agctcccaga ttttggacca gttgaaagct ccgagtttgg
     1261 gccagtttac caccacccca agtacacagc agaatagtac aagtcaccct acaactacta
     1321 cttcttggga cctcaagccc ccaacatccc agtcctcagt cctcagtcat cttgacttca
     1381 aatctcaacc tgagccatcc ccagttctta gccagttgag ccagcgacaa cagcaccaga
     1441 gccaggcagt cactgttcct cctcctggtt tggagtcctt tccttcccag gcaaaacttc
     1501 gagaatcaac acctggagac agtccctcca ctgtgaacaa gcttttgcag cttcccagca
     1561 cgaccattga aaatatctct gtgtctgtcc accagccaca gcccaaacac atcaaacttg
     1621 ctaagcggcg gataccccca gcttctaaga tcccagcttc tgcagtggaa atgcctggtt
     1681 cagcagatgt cacaggatta aatgtgcagt ttggggctct ggaatttggg tcagaacctt
     1741 ctctctctga atttggatca gctccaagca gtgaaaatag taatcagatt cccatcagct
     1801 tgtattcgaa gtctttaagt gagcctttga atacatcttt atcaatgacc agtgcagtac
     1861 agaactccac atatacaact tccgtcatta cctcctgcag tctgacaagc tcatcactga
     1921 attctgctag tccagtagca atgtcttcct cttatgacca gagttctgtg cataacagga
     1981 tcccatacca aagccctgtg agttcatcag agtcagctcc aggaaccatc atgaatggac
     2041 atggtggtgg tcgaagtcag cagacactag acactccaaa gacaacaggc cctccctctg
     2101 ccctcccgtc tgtgagctcc ctgcccagca ccacctcctg cactgcactt ctgccgtcca
     2161 catcccagca cactggcgac ctgactagca gccctctctc tcagcttagc agttcgctct
     2221 ccagccacca gagcagcctc tctgcacatg cagccctctc ctcgagcacg tcacacacac
     2281 atgccagtgt ggagagcgcc tcttcccacc agtcctcagc caccttctcc acggcagcga
     2341 cctccgtctc aagttccgca tcctcaggcg ccagcctgtc cagtagcatg aacaccgcga
     2401 acagcctctg tctgggtggg acccccgcga gtgcatccag cagcagtagc agggccgcgc
     2461 ccttggtgac ctcaggcaaa gcacccccaa acttacctca gggggtgcct cccctgctgc
     2521 acaaccagta cctcgtaggt cccggaggac tgcttcctgc ctacccgatc tatggctatg
     2581 acgagctcca gatgctgcag tcacggctgc cagtggacta ctatggaatt ccctttgctg
     2641 cacccacagc gcttgccagc cgagatggga gcctagctaa taatccatat ccaggtgatg
     2701 tcacaaagtt tggccgtggg gactctgcat cccctgcacc cgctaccaca ccagctcagc
     2761 cacagcagag ccaatcacag acccaccaca cagcccagca gcccttcgtg aatcctgcac
     2821 tgccacctgg ctatagctac actggtcttc cctactacac aggcatgccc agtgccttcc
     2881 agtatggccc caccatgttt gtccctccag cctcagccaa gcaacatggg gtgaacctca
     2941 gcactcccac acctcccttc cagcaggcca gtggttatgg ccagcacggc tacagtacag
     3001 gttatgacga cctgacccag gggacagcag caggagacta ctccaaaggt ggctatgctg
     3061 gatcatcgca ggcaccaaac aagtctgcag gttctgggcc tggcaaagga gtatcagtgt
     3121 cttcaagcac cactggtcta cctgatatga ctggttctgt ctacaataag acacagactt
     3181 ttgacaagca gggatttcat gcagggacgc ctccaccttt cagcctgccc tcggtcttgg
     3241 gctccactgg gcccctggcc tcgggagcgg cccctggcta tgcaccccca ccattcctac
     3301 acatcttgcc agcccaccag cagccccact cacagctgct gcaccaccac cttccgcagg
     3361 atgcacagag tggctcgggt cagcgcagcc agcccagctc cctgcagccc aagtctcaag
     3421 cctccaaacc tgcctacggc aactctccat actggacaaa ctaaacccag aagagagggg
     3481 tgggctgggg caaggcttat cctgggcagg agagaacaca cgagcacgta tttgggagcc
     3541 cagtgccctt tcctagaatt cccgacatgt gtcagccatg cctctgtggg gagtctgcct
     3601 cccagactgg ctactgtatg taatgtattt atgtatgtat ttgtaaatgt gatagaagtc
     3661 tgggggggag ttgggggatg gcggcagatg ttagccaggt ctgccctccc cattcaagcc
     3721 ccttctccac tgtagcaaaa taagcacccc caccccatct gccttcaggt cttcttcaca
     3781 gcctgcactg cccagtgggc cactaggggc agtctctgga agggctggtt caaggctgtt
     3841 tgggtatagg ggtcaggtac caatgaagaa tcacgacttg tctcactcct ttggaaattg
     3901 ttttctttcc tgtgtaatta cttcatacct ctgtttttga gaaactgttc cgtttgtcat
     3961 ctgtcatggt ctccttccac caaatcttca tctgggaata gcagcggtat ccctccaccc
     4021 aagtatggcc acctgtttgt cttcatatag aacaggggct tctggtctgg tcatgtccct
     4081 agagacttac tagagactgg ctgaccatga aaaaaaaaaa aataatctga gttattcagc
     4141 cagtcagctc ccctttaaaa atctaaggta tctccaagca acacatctcc attctagttg
     4201 tcttgaacca cgtgggcaac tgtttcaggg gttttctctt gcccaatccc cacctaataa
     4261 agttctgaga gcatg
//
