LOCUS       NM_145253               1374 bp    mRNA    linear   PRI 06-JUN-2024
DEFINITION  Homo sapiens UBA like domain containing 1 (UBALD1), transcript
            variant 1, mRNA.
ACCESSION   NM_145253
VERSION     NM_145253.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1374)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 1374)
  AUTHORS   Wan,D., Gong,Y., Qin,W., Zhang,P., Li,J., Wei,L., Zhou,X., Li,H.,
            Qiu,X., Zhong,F., He,L., Yu,J., Yao,G., Jiang,H., Qian,L., Yu,Y.,
            Shu,H., Chen,X., Xu,H., Guo,M., Pan,Z., Chen,Y., Ge,C., Yang,S. and
            Gu,J.
  TITLE     Large-scale cDNA transfection screening for genes related to cancer
            development and progression
  JOURNAL   Proc Natl Acad Sci U S A 101 (44), 15724-15729 (2004)
   PUBMED   15498874
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 Dec 14:101(50):17565]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC023830.9.
            
            On Nov 23, 2018 this sequence version replaced NM_145253.2.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC062534.1, SRR3476690.244075.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000283474.12/ ENSP00000283474.6
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-211               AC023830.9         84386-84596         c
            212-274             AC023830.9         80201-80263         c
            275-1374            AC023830.9         78592-79691         c
FEATURES             Location/Qualifiers
     source          1..1374
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16p13.3"
     gene            1..1374
                     /gene="UBALD1"
                     /gene_synonym="FAM100A; PP11303"
                     /note="UBA like domain containing 1"
                     /db_xref="GeneID:124402"
                     /db_xref="HGNC:HGNC:29576"
     exon            1..211
                     /gene="UBALD1"
                     /gene_synonym="FAM100A; PP11303"
                     /inference="alignment:Splign:2.1.0"
     CDS             92..625
                     /gene="UBALD1"
                     /gene_synonym="FAM100A; PP11303"
                     /note="isoform 1 is encoded by transcript variant 1;
                     protein FAM100A; family with sequence similarity 100,
                     member A; UBA-like domain-containing protein 1"
                     /codon_start=1
                     /product="UBA-like domain-containing protein 1 isoform 1"
                     /protein_id="NP_660296.1"
                     /db_xref="CCDS:CCDS10518.1"
                     /db_xref="GeneID:124402"
                     /db_xref="HGNC:HGNC:29576"
                     /translation="MSVNMDELKHQVMINQFVLTAGCAADQAKQLLQAAHWQFETALS
                     AFFQETNIPYSHHHHQMMCTPANTPATPPNFPDALTMFSRLKASESFHSGGSGSPMAA
                     TATSPPPHFPHAATSSSAASSWPTAASPPGGPQHHQPQPPLWTPTPPSPASDWPPLAP
                     QQATSEPRAHPAMEAER"
     exon            212..274
                     /gene="UBALD1"
                     /gene_synonym="FAM100A; PP11303"
                     /inference="alignment:Splign:2.1.0"
     exon            275..1374
                     /gene="UBALD1"
                     /gene_synonym="FAM100A; PP11303"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1346..1351
                     /regulatory_class="polyA_signal_sequence"
                     /gene="UBALD1"
                     /gene_synonym="FAM100A; PP11303"
                     /note="hexamer: AACAAA"
     polyA_site      1374
                     /gene="UBALD1"
                     /gene_synonym="FAM100A; PP11303"
                     /note="major polyA site"
ORIGIN      
        1 gtattagccg gagccggctc gctaatggtg gacgcgtgag gcggaggcgc gggcggagga
       61 gggaggccgg agcgggcagc gcggcggcgc catgtccgtg aacatggacg agctcaagca
      121 ccaggtcatg atcaaccagt tcgtgctgac ggcgggctgc gcggccgacc aggcgaagca
      181 actgctgcag gcggcccact ggcagttcga gacagccctc agcgcctttt tccaggagac
      241 caacatcccc tacagccacc atcaccacca gatgatgtgc acccccgcca atacccctgc
      301 tacacccccc aacttccctg acgctctcac catgttctcc cgtctcaagg cctccgagag
      361 cttccacagc ggtggcagcg gcagcccgat ggccgcgaca gccacgtcac ccccgccaca
      421 cttcccccat gccgccacca gcagctctgc ggcctccagc tggcccacgg cggcctcgcc
      481 cccggggggc ccacagcacc accagccaca gccgcccctg tggactccaa cacccccttc
      541 tccggcttca gactggccac ccctggcccc ccaacaggcc acctcagaac ccagggccca
      601 ccctgccatg gaggcagaga gataagggag gcccctcccc cctcccggag gccaggaccc
      661 cgtggggcgg gggagaggac gtctctgcgg gcccccttca ccccttttct gtctgcaccc
      721 cttgttcccc ggagccctgg aggggagagc gcggactcta gccaggcagg gacacgtctg
      781 gtgccagaac acgcagctgc ccacacgcaa ggtcatggcc ccagcggccc cggcacatgg
      841 agtggttcag cgcggcctgg gtgcctggcg gacagaactt cagagaccac gcagccttcc
      901 ttcgaagacg cacctgccca gcccagccca ggggtgccgt ggaggaccac cctggcagag
      961 acattgctga tccctggctt ggagctcctt gggggccggc aggcctcgac ccccacccta
     1021 gggaatgcag agcctctccg catgtgtgcg cgtggccgtg tctgtgtatt tctacgtgtg
     1081 tcgctcttca gaagcaacct agttcctggg gcagctggac tttgcatgtt agtgtgagcc
     1141 cccagccccc tgcccgccgc cccctcccca gggccctgcc tcctccccac cccctcgtca
     1201 gccagcgttg ctgttccttg cagagaaaag gattgtggga aactccagga ctcttcccac
     1261 cgcctcccag cgcctgcctg ctggggctgc ctgcatgcct cccctgcacc tgggggtacc
     1321 cgcatccact tcctttcccc cttttaacaa aagagaagaa cgaattccaa acca
//
