LOCUS       XM_047428845            3859 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens UDP-N-acetylglucosamine pyrophosphorylase 1
            (UAP1), transcript variant X2, mRNA.
ACCESSION   XM_047428845
VERSION     XM_047428845.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3859
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..3859
                     /gene="UAP1"
                     /gene_synonym="AGX; AGX1; AGX2; SPAG2"
                     /note="UDP-N-acetylglucosamine pyrophosphorylase 1;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 61 ESTs, 344 long SRA reads, 3 Proteins,
                     and 100% coverage of the annotated genomic feature by
                     RNAseq alignments, including 65 samples with support for
                     all annotated introns"
                     /db_xref="GeneID:6675"
                     /db_xref="HGNC:HGNC:12457"
                     /db_xref="MIM:602862"
     CDS             417..1982
                     /gene="UAP1"
                     /gene_synonym="AGX; AGX1; AGX2; SPAG2"
                     /codon_start=1
                     /product="UDP-N-acetylhexosamine pyrophosphorylase isoform
                     X2"
                     /protein_id="XP_047284801.1"
                     /db_xref="GeneID:6675"
                     /db_xref="HGNC:HGNC:12457"
                     /db_xref="MIM:602862"
                     /translation="MNINDLKLTLSKAGQEHLLRFWNELEEAQQVELYAELQAMNFEE
                     LNFFFQKAIEGFNQSSHQKNVDARMEPVPREVLGSATRDQDQLQAWESEGLFQISQNK
                     VAVLLLAGGQGTRLGVAYPKGMYDVGLPSRKTLFQIQAERILKLQQVAEKYYGNKCII
                     PWYIMTSGRTMESTKEFFTKHKYFGLKKENVIFFQQGMLPAMSFDGKIILEEKNKVSM
                     APDGNGGLYRALAAQNIVEDMEQRGIWSIHVYCVDNILVKVADPRFIGFCIQKGADCG
                     AKVVEKTNPTEPVGVVCRVDGVYQVVEYSEISLATAQKRSSDGRLLFNAGNIANHFFT
                     VPFLRDVVNVYEPQLQHHVAQKKIPYVDTQGQLIKPDKPNGIKMEKFVFDIFQFAKKF
                     VVYEVLREDEFSPLKNADSQNGKDNPTTARHALMSLHHCWVLNAGGHFIDENGSRLPA
                     IPRATNGKSETITADVNHNLKDANDVPIQCEISPLISYAGEGLESYVADKEFHAPLII
                     DENGVHELVKNGI"
ORIGIN      
        1 gtctgtgctc ccggcgctga cgtgtctggg cggtcggctt ccactccttc aggcgtcggc
       61 agccactagt cgtggcgaga ggggcggggt ggccggggct ggcgctccac ttggcccccg
      121 ctcccggccc gccccgccgc cgcggccccc cggatgaggg tatatattcg gagcgagcgc
      181 gggacgccga tgagtggccg cgcggaagga gctggagacg gtcgtagctg cggtcgcgcc
      241 gagaaagaag gatggtattg gagggctgag cacacgtatg ctgaacatat ggctgcttga
      301 actttggcct gtcgctgtgc tacacttact tctacatggt ttatgaaatc tgaaatcagg
      361 tttacaggta catacattac acccctattt ctacaaagct tggctattag agcattatga
      421 acattaatga cctcaaactc acgttgtcca aagctgggca agagcaccta ctacgtttct
      481 ggaatgagct tgaagaagcc caacaggtag aactttatgc agagctccag gccatgaact
      541 ttgaggagct gaacttcttt ttccaaaagg ccattgaagg ttttaaccag tcttctcacc
      601 aaaagaatgt ggatgcacga atggaacctg tgcctcgaga ggtattaggc agtgctacaa
      661 gggatcaaga tcagctccag gcctgggaaa gtgaaggact tttccagatt tctcagaata
      721 aagtagcagt tcttcttcta gctggtgggc aggggacaag actcggcgtt gcatatccta
      781 aggggatgta tgatgttggt ttgccatccc gtaagacact ttttcagatt caagcagagc
      841 gtatcctgaa gctacagcag gttgctgaaa aatattatgg caacaaatgc attattccat
      901 ggtatataat gaccagtggc agaacaatgg aatctacaaa ggagttcttc accaagcaca
      961 agtactttgg tttaaaaaaa gagaatgtaa tcttttttca gcaaggaatg ctccccgcca
     1021 tgagttttga tgggaaaatt attttggaag agaagaacaa agtttctatg gctccagatg
     1081 ggaatggtgg tctttatcgg gcacttgcag cccagaatat tgtggaggat atggagcaaa
     1141 gaggcatttg gagcattcat gtctattgtg ttgacaacat attagtaaaa gtggcagacc
     1201 cacggttcat tggattttgc attcagaaag gagcagactg tggagcaaag gtggtagaga
     1261 aaacgaaccc tacagaacca gttggagtgg tttgccgagt ggatggagtt taccaggtgg
     1321 tagaatatag tgagatttcc ctggcaacag ctcaaaaacg aagctcagac ggacgactgc
     1381 tgttcaatgc ggggaacatt gccaaccatt tcttcactgt accatttctg agagatgttg
     1441 tcaatgttta tgaacctcag ttgcagcacc atgtggctca aaagaagatt ccttatgtgg
     1501 atacccaagg acagttaatt aagccagaca aacccaatgg aataaagatg gaaaaatttg
     1561 tctttgacat cttccagttt gcaaagaagt ttgtggtata tgaagtattg cgagaagatg
     1621 agttttcccc actaaagaat gctgatagtc agaatgggaa agacaaccct actactgcaa
     1681 ggcatgcttt gatgtccctt catcattgct gggtcctcaa tgcagggggc catttcatag
     1741 atgaaaatgg ctctcgcctt ccagcaattc cccgtgctac aaatgggaag tcagagacca
     1801 tcacagctga tgtcaatcac aacttgaagg atgccaatga tgtaccaatc caatgtgaaa
     1861 tctctcctct tatctcctat gctggagaag gattagaaag ttatgtggca gataaagaat
     1921 tccatgcacc tctaatcatc gatgagaatg gagttcatga gctggtgaaa aatggtattt
     1981 gaaccagata ccaagttttg tttgccacga taggaatagc ttttattttt gatagaccaa
     2041 ctgtgaacct acaagacgtc ttggacaact gaagtttaaa tatccacagg gttttatttt
     2101 gcttgttgaa ctcttagagc tattgcaaac ttcccaagat ccagatgact gaatttcaga
     2161 tagcattttt atgattccca actcattgaa ggtcttattt atataatttt ttccaagcca
     2221 aggagaccat tggccatcca ggaaatttcg tacagctgaa atataggcag gatgttcaac
     2281 atcagtttac ttgcagctgg aagcatttgt ttttgaagtt gtacatagta ataatatgtc
     2341 attgtacatg ttgaaaggtt tctatggtac taaaagtttg ttttatttta tcaaacatta
     2401 agctttttta agaaaataat tgggcagtga aataaatgta tcttcttgtc tctggagtgt
     2461 catttgtact tgaagaaatt atttcattga gaaaatatga aacttgggag aaactttaag
     2521 ataatgcata aaaacaaatt gatgcttcag tgaggttgca gagtcataga acttctttca
     2581 gtgaatatct aactttgggc tttatcttct tatcacttta taatagtagc tctcacccaa
     2641 agattatttt gtcctccacc caaaggggca tttggcaatg tctggagata tttttggttg
     2701 tgacaagtgg gaaagtgaag tggtaccact ggcatctaat agggattagg gatgtcacta
     2761 aacatcctac aatgcacagg atggtctcct acgacaaaga gttatctggc ctaaagtgtc
     2821 aatggtgtca aggtcgagaa gccttgtttc aaattattca tttactctgt tttgcccaaa
     2881 tatttggtgg cacttaggaa ttcaaaagaa tgtagtttct gaattttctc tggtaggcta
     2941 ttccagtttt ttgttattgt tgttgttatt ttagaggatt aaaaaaataa aaagacaaag
     3001 gtggttcttt aaatatgggc catagatcat tggtcattag taagggttct ctgtgtctaa
     3061 aatgctgttt gcatgaaaag actgagcttt ataaatgcat cttaaataat atttaagtat
     3121 tgaccaaaag tataaaaagg aacatctgga taaatgattc taaaaattat atctagaaaa
     3181 gagatgaata aatttcattt tccgctaaca agttgtcaca agataggatg tcattcatgg
     3241 ggtgggtctt ttgtttaagg atcacttttt tttttttttg aagagcatgt gatgttcata
     3301 tccatcaatc ttacctattt tttttttaac taaggcctaa atcattcatt tagcatattt
     3361 tctattttat ttcaataaca gctcaatttt gctattgtta tctattccag ttttcaaaaa
     3421 gattagtgaa gtttgacttc tcattgaaat gagctccaaa tgggttgtaa gaatggaatt
     3481 gcagagtctt tagctcctga atgccaaaaa ctgatactaa tggtatgatc cgtttctttt
     3541 tttcttgaac cttgctattt cctctgctat ttccacctgc tatttattct tctcctgttg
     3601 taagaaaata ctagtgatgc taggaaaagg gaagaatgga aatgggattg tgtagtggtt
     3661 ttgttggaga ggagcgatgg ctggggaaca ttgggtagtt aagagcaaac tctgagagcc
     3721 tctgagccat gaaatgataa ggtgatagca ttatgtattt ttatgagttc ttgttaaata
     3781 attgttataa ttcagaaaat acagaattgg gtaaaatgtt tatgaaaata aaagctagaa
     3841 taatttggca gtaacagta
//
