LOCUS       XM_047416371            5655 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens terminal uridylyl transferase 4 (TUT4),
            transcript variant X27, mRNA.
ACCESSION   XM_047416371
VERSION     XM_047416371.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5655
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..5655
                     /gene="TUT4"
                     /gene_synonym="PAPD3; TENT3A; ZCCHC11"
                     /note="terminal uridylyl transferase 4; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 80 ESTs, 1253 long SRA reads, 1 Protein, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 39 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:23318"
                     /db_xref="HGNC:HGNC:28981"
                     /db_xref="MIM:613692"
     CDS             256..4995
                     /gene="TUT4"
                     /gene_synonym="PAPD3; TENT3A; ZCCHC11"
                     /codon_start=1
                     /product="terminal uridylyltransferase 4 isoform X24"
                     /protein_id="XP_047272327.1"
                     /db_xref="GeneID:23318"
                     /db_xref="HGNC:HGNC:28981"
                     /db_xref="MIM:613692"
                     /translation="MEESKTLKSENHEPKKNVICEESKAVQVIGNQTLKARNDKSVKE
                     IENSSPNRNSSKKNKQNDICIEKTEVKSCKVNAANLPGPKDLGLVLRDQSHCKAKKFP
                     NSPVKAEKATISQAKSEKATSLQAKAEKSPKSPNSVKAEKASSYQMKSEKVPSSPAEA
                     EKGPSLLLKDMRQKTELQQIGKKIPSSFTSVDKVNIEAVGGEKCALQNSPRSQKQQTC
                     TDNTGDSDDSASGIEDVSDDLSKMKNDESNKENSSEMDYLENATVIDESALTPEQRLG
                     LKQAEERLERDHIFRLEKRSPEYTNCRYLCKLCLIHIENIQGAHKHIKEKRHKKNILE
                     KQEESELRSLPPPSPAHLAALSVAVIELAKEHGITDDDLRVRQEIVEEMSKVITTFLP
                     ECSLRLYGSSLTRFALKSSDVNIDIKFPPKMNHPDLLIKVLGILKKNVLYVDVESDFH
                     AKVPVVVCRDRKSGLLCRVSAGNDMACLTTDLLTALGKIEPVFIPLVLAFRYWAKRKP
                     PLLPCLLGSWIEGFDPKRMDDFQLKGIVEEKFVKWECNSSSATEKNSIAEENKAKADQ
                     PKDDTKKTETDNQSNAMKEKHGKSPLALETPNRVSLGQLWLELLKFYTLDFALEEYVI
                     CVRIQDILTRENKNWPKRRIAIEDPFSVKRNVARSLNSQLVYEYVVERFRAAYRYFAC
                     PQTKGGNKSTVDFKKREKGKISNKKPVKSNNMATNGCILLGETTEKINAEREQPVQCD
                     EMDCTSQRCIIDNNNLLVNELDFADHGQDSSSLSTSKSSEIEPKLDKKQDDLAPSETC
                     LKKELSQCNCIDLSKSPDPDKSTGTDCRSNLETESSHQSVCTDTSATSCNCKATEDAS
                     DLNDDDNLPTQELYYVFDKFILTSGKPPTIVCSICKKDGHSKNDCPEDFRKIDLKPLP
                     PMTNRFREILDLVCKRCFDELSPPCSEQHNREQILIGLEKFIQKEYDEKARLCLFGSS
                     KNGFGFRDSDLDICMTLEGHENAEKLNCKEIIENLAKILKRHPGLRNILPITTAKVPI
                     VKFEHRRSGLEGDISLYNTLAQHNTRMLATYAAIDPRVQYLGYTMKVFAKIFDGKQIP
                     QRMVDGWNAFFFDKTEELKKRLPSLGKNTESLGELWLGLLRFYTEEFDFKEYVISIRQ
                     KKLLTTFEKQWTSKCIAIEDPFDLNHNLGAGVSRKMTNFIMKAFINGRKLFGTPFYPL
                     IGREAEYFFDSRVLTDGELAPNDRCCRVCGKIGHYMKDCPKRKSLLFRLKKKDSEEEK
                     EGNEEEKDSRDVLDPRDLHDTRDFRDPRDLRCFICGDAGHVRRECPEVKLARQRNSSV
                     AAAQLVRNLVNAQQVAGSAQQQGDQSIRTRQSSECSESPSYSPQPQPFPQNSSQSAAI
                     TQPSSQPGSQPKLGPPQQGAQPPHQVQMPLYNFPQSPPAQYSPMHNMGLLPMHPLQIP
                     APSWPIHGPVIHSAPGSAPSNIGLNDPSIIFAQPAARPVAIPNTSHDGHWPRTVAPNS
                     LVNSGAVGNSEPGFRGLTPPIPWEHAPRPHFPLVPASWPYGLHQNFMHQGNARFQPNK
                     PFYTQDRCATRRCRERCPHPPRGNVSE"
ORIGIN      
        1 agttcgcggc gcggcggaca tggcggtgga gtcctgagct agtcgtgtcc cggcctccag
       61 cggcggcagc ggcgacggcg gcggcagcag gaggcggagg gagagcagga gccactgaga
      121 tgaggaggcg tcgcgcgcgc ctgtagctcg cgggcctcgc agtttgcttg cctaaactgg
      181 acttgaagca atttaaacta ctggagatct gccattttat aatatcacaa ttggaaagaa
      241 acagattttc aaataatgga agagtctaaa accttaaaaa gtgaaaatca tgaaccaaag
      301 aagaatgtta tttgtgaaga aagcaaagca gttcaagtta taggtaatca aacattgaaa
      361 gctagaaatg ataaatccgt aaaagaaatt gagaacagct ctccaaatag gaatagtagt
      421 aaaaaaaata agcaaaatga tatttgtata gaaaaaacag aagttaaatc atgtaaagta
      481 aatgctgcca accttccagg tcctaaagat ttggggttag tccttcgaga tcaaagtcat
      541 tgcaaagcaa aaaaatttcc taattcaccg gtgaaagccg aaaaggcaac catttcacag
      601 gcaaaatcag aaaaggcaac cagtttacag gcaaaagcag aaaaatcacc aaagtcacct
      661 aattcagtga aagcagaaaa agcatccagt tatcagatga agtcagaaaa agtaccaagt
      721 tcaccagcag aagcagaaaa gggacccagt ttactgttga aagacatgag acagaagaca
      781 gaattacaac agattggaaa aaaaattcca agctccttta cttctgtgga caaagtgaat
      841 attgaagctg tagggggaga aaaatgtgct ctgcaaaact caccacgatc tcagaagcaa
      901 cagacatgta cagataatac tggtgattct gatgatagtg cttcaggaat tgaagacgta
      961 tcggacgatt taagtaaaat gaagaatgat gaatctaata aagaaaattc ttcagagatg
     1021 gactacttag aaaatgccac tgtgatagat gaatctgcat tgacacctga gcagaggctg
     1081 gggttgaaac aagcagaaga acgcttagaa agagatcaca tctttcgact tgaaaaacga
     1141 tcaccagaat ataccaattg tcggtatcta tgcaaacttt gcttaattca cattgaaaat
     1201 atccaggggg ctcataaaca tataaaggag aaacgacata agaaaaatat tttggaaaaa
     1261 caagaagaaa gtgagcttcg ttctctgcca cctccttccc ctgcccactt ggctgcttta
     1321 agtgttgcag tcattgaatt agcaaaagaa catggaataa cagatgatga cctcagagtc
     1381 cgtcaggaaa ttgtggagga aatgtcaaag gttataacga catttttacc agaatgttca
     1441 cttaggttgt atggctcatc tctgactaga tttgctctga aaagtagtga tgttaatata
     1501 gatataaaat ttcctcccaa gatgaatcat ccagatcttc tgataaaagt acttgggatt
     1561 ttaaagaaaa atgtattata tgtagatgtg gaatctgatt ttcacgctaa agttcctgtt
     1621 gtggtgtgca gagatcgaaa aagtggttta ctttgtagag tgagtgcagg aaacgatatg
     1681 gcatgtctca ctactgattt acttactgcc cttggcaaaa tagaacctgt ctttattccc
     1741 ttggtgttag cctttcgcta ctgggctaag agaaaacccc ctcttcttcc ttgcttactt
     1801 ggaagttgga ttgaaggctt tgacccaaaa agaatggatg actttcagct gaagggcata
     1861 gtagaagaga agtttgtgaa gtgggaatgt aattcaagta gtgcaactga gaaaaactca
     1921 attgctgagg aaaacaaagc taaggcagac caaccaaaag atgataccaa gaagacagaa
     1981 acagacaacc aaagtaatgc catgaaggaa aaacatggca aatctccttt agcattggaa
     2041 acaccaaatc gggtatcctt gggacagtta tggttagagc tgcttaaatt ctacacactg
     2101 gattttgctt tggaggaata tgtcatatgt gtacggatac aagatatttt aacaagagaa
     2161 aataaaaact ggcctaaaag gcgaatagcc attgaagatc cattttcagt caagaggaat
     2221 gttgcacgga gcttaaacag ccagctggtt tacgaatatg ttgtggagag atttagggca
     2281 gcttatcggt attttgcctg tcctcagacg aagggtggaa ataagtctac agtggatttc
     2341 aagaaaagag agaaggggaa aataagcaat aagaaaccag tcaagtcgaa caatatggca
     2401 accaatggtt gtattctgct tggggaaacc acagaaaaaa taaatgcaga aagagagcaa
     2461 cctgttcaat gtgatgaaat ggactgtaca tcacagagat gtattattga caacaacaat
     2521 ttgttggtaa atgaactaga ttttgctgac cacggacagg actcttcatc tctttctacc
     2581 agcaaaagca gtgaaataga gccaaaatta gataagaaac aagatgattt agcgccttca
     2641 gaaacttgtt taaaaaaaga gctcagccaa tgtaattgca ttgatttgtc taagtcgcct
     2701 gacccagata aatctactgg aacagactgc aggtcaaatt tagaaacaga gagttcacat
     2761 cagagtgtgt gcaccgacac atctgctacc tcttgcaact gcaaagctac agaagatgct
     2821 tctgacctta atgatgatga taacctcccc acccaggaat tatattatgt gtttgataag
     2881 tttattttaa cctctggcaa gccaccaacg atagtatgca gcatctgcaa aaaggatggc
     2941 cattcaaaga atgattgccc agaggatttt aggaaaattg atttaaaacc tctaccacca
     3001 atgacaaacc gatttcggga aatacttgat ttagtatgta aaagatgttt tgatgagtta
     3061 tcaccacctt gttctgaaca acacaacagg gagcaaattt taattggctt ggaaaagttt
     3121 attcaaaaag aatatgatga aaaggcaagg ttgtgcttat ttggctcttc taagaatgga
     3181 tttggatttc gtgatagtga tctggatatt tgtatgaccc tggaaggcca tgaaaatgca
     3241 gagaaattaa attgtaagga aataattgaa aatttggcaa aaattcttaa gagacatcca
     3301 ggtttaagaa acattttgcc tataactact gccaaagtgc ctatagtaaa atttgaacac
     3361 aggcgaagtg ggttagaagg cgatatcagt ttatataata cgttggctca acataacaca
     3421 agaatgctag ctacttatgc agctattgat cctagagtgc agtatttggg atatactatg
     3481 aaagtgtttg ctaagatctt tgatggaaaa cagattccac agagaatggt tgatggatgg
     3541 aatgctttct tctttgataa aacagaagaa ctgaaaaagc gtttaccttc acttggaaag
     3601 aacacagaat cattagggga gctttggctg ggactgcttc gtttctatac tgaagagttt
     3661 gatttcaagg aatatgtaat tagcattcgg cagaaaaagc tgttgacaac ttttgagaag
     3721 cagtggactt ccaagtgcat tgcaattgaa gacccttttg acttgaatca taaccttggt
     3781 gctggagttt ccagaaaaat gaccaatttc atcatgaaag catttatcaa tggaaggaaa
     3841 ctttttggta ccccttttta tccactcatt ggcagagaag ctgagtactt ctttgattcc
     3901 agagtattaa cagatggaga actggctccc aatgatagat gttgccgtgt gtgtggaaaa
     3961 ataggccact acatgaaaga ctgccctaaa aggaaaagtt tactgtttag actaaagaag
     4021 aaagacagtg aagaagagaa ggaagggaat gaagaagaga aagattcccg agatgttctt
     4081 gacccccgag acctccacga tactcgagac tttagagacc cgagagacct cagatgtttt
     4141 atatgtggag atgctggaca tgtacgaagg gagtgcccag aggtcaagct ggcccgtcag
     4201 aggaatagca gtgtggcagc agcccagctg gtccgcaacc ttgtaaatgc tcaacaggtg
     4261 gctggttcag ctcagcaaca gggtgatcag tccataagga ctagacagtc atcagaatgt
     4321 tctgaatcac catcttattc tcctcagcct cagccatttc cacagaactc ttcccagtca
     4381 gctgctatta ctcagccttc atctcagcca ggatcccaac ctaagcttgg cccacctcag
     4441 cagggagccc aacctcccca tcaggtccag atgccactgt ataactttcc ccagtcacca
     4501 ccagctcagt attctcccat gcacaatatg ggattgttgc caatgcaccc tctccagatc
     4561 cctgccccgt cctggcccat ccatggccca gtgatccact ctgcaccagg cagtgccccc
     4621 agcaatattg gcctaaatga tcccagcatc atctttgcac agcctgctgc cagacctgtg
     4681 gcaatcccta acacgtctca cgatggacac tggccccgta ctgtggctcc aaattccctg
     4741 gtaaacagtg gtgcagtggg gaattcagag ccaggctttc gaggactgac tcctccaatt
     4801 ccttgggaac atgcaccgcg tccccatttc ccccttgtcc cagcttcgtg gccttatggt
     4861 ttgcatcaaa acttcatgca tcagggaaat gcccgattcc agcccaacaa acctttctat
     4921 actcaagaca gatgtgccac ccgtcggtgt agagagcgtt gtccccaccc accaagagga
     4981 aacgtgtcgg agtaatgcga gtccattttc tttcagctgg tctaccgatg cacagcaacc
     5041 agccaatcct gctgtctcaa gggtatccgt acctcaatgt cagttacatt cagcagaaaa
     5101 agtgacattt aatggaaagc aaaacaaatc aggtcctgat ttaaaatttt aacacgttta
     5161 gatagcttat ttaaattcta agactgtttt tacagactgt attatttgta tataaatatg
     5221 aactatagtt tttactagta tcaccaaatt gagtgataca aatttcatct attttattac
     5281 cctattttta agggaatttt atgttttgtt taaccttgat gaattgtata aagagagaat
     5341 ttaaaaaatt acattcttta ttttctatta gctgtattca tactttggtt gcttcagact
     5401 ttatatattg ttcttaaaag ttaggaaaga atttcatgtg ttttaaattg tcacttctat
     5461 tctttacaga accttgtagt gccaaaaact ttttaaaagg taaaaaaata aaataaaatt
     5521 acaacatgaa gattcagatt ttttttcttt tccatacttg tatattgaac attcaaactt
     5581 gaatggaaag ttgattttgt ctgtatttga agtacttcta ttttaagtta ataaatcttt
     5641 ttgacaagag ttaaa
//
