LOCUS       XM_047422263            2196 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens tumor suppressor candidate 3 (TUSC3),
            transcript variant X1, mRNA.
ACCESSION   XM_047422263
VERSION     XM_047422263.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000008.11) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2196
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="8"
     gene            1..2196
                     /gene="TUSC3"
                     /gene_synonym="D8S1992; M33; MagT2; MRT22; MRT7; N33;
                     OST3A; SLC58A2"
                     /note="tumor suppressor candidate 3; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 23
                     ESTs, 190 long SRA reads, 1 Protein, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 27 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:7991"
                     /db_xref="HGNC:HGNC:30242"
                     /db_xref="MIM:601385"
     CDS             53..970
                     /gene="TUSC3"
                     /gene_synonym="D8S1992; M33; MagT2; MRT22; MRT7; N33;
                     OST3A; SLC58A2"
                     /codon_start=1
                     /product="tumor suppressor candidate 3 isoform X1"
                     /protein_id="XP_047278219.1"
                     /db_xref="GeneID:7991"
                     /db_xref="HGNC:HGNC:30242"
                     /db_xref="MIM:601385"
                     /translation="MEWSSRRSIFRMNGDKFRKFIKAPPRNYSMIVMFTALQPQRQCS
                     VCRQANEEYQILANSWRYSSAFCNKLFFSMVDYDEGTDVFQQLNMNSAPTFMHFPPKG
                     RPKRADTFDLQRIGFAAEQLAKWIADRTDVHIRVFRPPNYSGTIALALLVSLVGGLLY
                     LRRNNLEFIYNKTGWAMVSLCIVFAMTSGQMWNHIRGPPYAHKNPHNGQVSYIHGSSQ
                     AQFVAESHIILVLNAAITMGMVLLNEAATSKGDVGKRRIICLVGLGLVVFFFSFLLSI
                     FRSKYHGYPYRHAVVLTVKSSVWRKYIHP"
     polyA_site      2196
                     /gene="TUSC3"
                     /gene_synonym="D8S1992; M33; MagT2; MRT22; MRT7; N33;
                     OST3A; SLC58A2"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 taatttctgt gtttaattgc agaatctttt agctgaaaaa gtagagcagc tgatggaatg
       61 gagttccaga cgctcaatct tccgaatgaa tggtgataaa ttccgaaaat ttataaaggc
      121 accacctcga aactattcca tgattgttat gttcactgct cttcagcctc agcggcagtg
      181 ttctgtgtgc aggcaagcta atgaagaata tcaaatactg gcgaactcct ggcgctattc
      241 atctgctttt tgtaacaagc tcttcttcag tatggtggac tatgatgagg ggacagacgt
      301 ttttcagcag ctcaacatga actctgctcc tacattcatg cattttcctc caaaaggcag
      361 acctaagaga gctgatactt ttgacctcca aagaattgga tttgcagctg agcaactagc
      421 aaagtggatt gctgacagaa cggatgttca tattcgggtt ttcagaccac ccaactactc
      481 tggtaccatt gctttggccc tgttagtgtc gcttgttgga ggtttgcttt atttgagaag
      541 gaacaacttg gagttcatct ataacaagac tggttgggcc atggtgtctc tgtgtatagt
      601 ctttgctatg acttctggcc agatgtggaa ccatatccgt ggacctccat atgctcataa
      661 gaacccacac aatggacaag tgagctacat tcatgggagc agccaggctc agtttgtggc
      721 agaatcacac attattctgg tactgaatgc cgctatcacc atggggatgg ttcttctaaa
      781 tgaagcagca acttcgaaag gcgatgttgg aaaaagacgg ataatttgcc tagtgggatt
      841 gggcctggtg gtcttcttct tcagttttct actttcaata tttcgttcca agtaccacgg
      901 ctatccttat agacatgccg tggtgcttac tgtgaaatct tctgtttgga gaaaatacat
      961 acatccatga accggggaat aacaatataa agtgtcacaa gctaagtggc tggcagatct
     1021 gttgtatgga aataatttac aggtgagaaa gatcactgtg ggtctgagaa aggaagactc
     1081 cagaagaagg cttgaattag gctaaaattc aacacagcat ttagacaaag gagagaggag
     1141 gggctgaggg tatttcatga gccgaaagtc ataatttgtg tacaaaggaa tgggaagaga
     1201 aatatgttca tggtatattc tgaggattat gagtatactg ctatggtgtg acagccttaa
     1261 tatgtactac tcaatagtga acgtttctgg tttaaaatac attaattaga cagaaagaaa
     1321 tatatgaaaa ggaagatata tacacaaaag gaaatattct taaccaattt gggtgaattt
     1381 tatgacagtt ctctaattca aattctagat gtttgcaaaa ctaataatta tttttccaga
     1441 tgagtttttg ggattttttc cagaacatca tagtgttctg gtattttagt actgcaaagg
     1501 atcatggaga tcatatcact gaaattcatt ttatagatga gaccaagaga gtatctttat
     1561 tttatgacag aagcagaaaa tctgactctg cttacttgtc tctcctgtgc catgttttgt
     1621 gtagaaaaac gtgattcgta tattcctata agtagaaaat tatcccagaa tcaaagttga
     1681 aaataacatg aggtcaaatg tataatgacc tcaataatct gatagccaaa gcctctaaga
     1741 aaaatgttga caattagata aatgttcagc accaagataa taacttactt tggcctcttc
     1801 aattcttgtg agctccagaa gttcaagaga tgacgatttt actcaaggaa aaacttcctt
     1861 attcttgaac ttggtacaaa tatatgcaat gaaacaaaag gaaatctaca taaaaactaa
     1921 gggacactga caaaatctac ttattaaaca aatttaagta atttttatat cttattcttt
     1981 actaatgaaa gctgctatag tttacataga tgtgattccc tttttatgtt ttttctaatc
     2041 ctataatgtt ctcttcatgt atcctcagat catttctgag atttgttctt tcttatctga
     2101 atttcatgac ttagttatcc agctattcta ctgtccaatt taaaaaatcc ctctaattat
     2161 atcttcccag atcacattaa agccttctaa tatgtc
//
