LOCUS       NM_024686               7980 bp    mRNA    linear   PRI 19-SEP-2024
DEFINITION  Homo sapiens tubulin tyrosine ligase like 7 (TTLL7), transcript
            variant 1, mRNA.
ACCESSION   NM_024686
VERSION     NM_024686.6
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7980)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 7980)
  AUTHORS   Garnham,C.P., Vemu,A., Wilson-Kubalek,E.M., Yu,I., Szyk,A.,
            Lander,G.C., Milligan,R.A. and Roll-Mecak,A.
  TITLE     Multivalent Microtubule Recognition by Tubulin Tyrosine Ligase-like
            Family Glutamylases
  JOURNAL   Cell 161 (5), 1112-1123 (2015)
   PUBMED   25959773
REFERENCE   3  (bases 1 to 7980)
  AUTHORS   Cornelis,M.C., Fornage,M., Foy,M., Xun,P., Gladyshev,V.N.,
            Morris,S., Chasman,D.I., Hu,F.B., Rimm,E.B., Kraft,P., Jordan,J.M.,
            Mozaffarian,D. and He,K.
  TITLE     Genome-wide association study of selenium concentrations
  JOURNAL   Hum Mol Genet 24 (5), 1469-1477 (2015)
   PUBMED   25343990
REFERENCE   4  (bases 1 to 7980)
  AUTHORS   Niu,N., Schaid,D.J., Abo,R.P., Kalari,K., Fridley,B.L., Feng,Q.,
            Jenkins,G., Batzler,A., Brisbin,A.G., Cunningham,J.M., Li,L.,
            Sun,Z., Yang,P. and Wang,L.
  TITLE     Genetic association with overall survival of taxane-treated lung
            cancer patients - a genome-wide association study in human
            lymphoblastoid cell lines followed by a clinical association study
  JOURNAL   BMC Cancer 12, 422 (2012)
   PUBMED   23006423
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 7980)
  AUTHORS   Comuzzie,A.G., Cole,S.A., Laston,S.L., Voruganti,V.S., Haack,K.,
            Gibbs,R.A. and Butte,N.F.
  TITLE     Novel genetic loci identified for the pathophysiology of childhood
            obesity in the Hispanic population
  JOURNAL   PLoS One 7 (12), e51954 (2012)
   PUBMED   23251661
REFERENCE   6  (bases 1 to 7980)
  AUTHORS   Heinzen,E.L., Need,A.C., Hayden,K.M., Chiba-Falek,O., Roses,A.D.,
            Strittmatter,W.J., Burke,J.R., Hulette,C.M., Welsh-Bohmer,K.A. and
            Goldstein,D.B.
  TITLE     Genome-wide scan of copy number variation in late-onset Alzheimer's
            disease
  JOURNAL   J Alzheimers Dis 19 (1), 69-77 (2010)
   PUBMED   20061627
REFERENCE   7  (bases 1 to 7980)
  AUTHORS   Janke,C., Rogowski,K., Wloga,D., Regnard,C., Kajava,A.V.,
            Strub,J.M., Temurak,N., van Dijk,J., Boucher,D., van Dorsselaer,A.,
            Suryavanshi,S., Gaertig,J. and Edde,B.
  TITLE     Tubulin polyglutamylase enzymes are members of the TTL domain
            protein family
  JOURNAL   Science 308 (5729), 1758-1762 (2005)
   PUBMED   15890843
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            HY139706.1, BC032829.1, AK126792.1, AL138844.24, AL035706.10 and
            AI374651.1.
            
            On Nov 22, 2018 this sequence version replaced NM_024686.5.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803616.73822.1,
                                           SRR1660809.105833.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000260505.13/ ENSP00000260505.8
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-25                HY139706.1         58-82
            26-520              BC032829.1         3-497
            521-3303            AK126792.1         436-3218
            3304-3699           AL138844.24        2001-2396           c
            3700-7620           AL035706.10        139670-143590       c
            7621-7972           AI374651.1         12-363              c
            7973-7980           AL035706.10        139310-139317       c
FEATURES             Location/Qualifiers
     source          1..7980
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p31.1"
     gene            1..7980
                     /gene="TTLL7"
                     /note="tubulin tyrosine ligase like 7"
                     /db_xref="GeneID:79739"
                     /db_xref="HGNC:HGNC:26242"
                     /db_xref="MIM:618813"
     exon            1..202
                     /gene="TTLL7"
                     /inference="alignment:Splign:2.1.0"
     exon            203..403
                     /gene="TTLL7"
                     /inference="alignment:Splign:2.1.0"
     CDS             379..3042
                     /gene="TTLL7"
                     /note="isoform 1 is encoded by transcript variant 1;
                     tubulin polyglutamylase TTLL7; testis development protein
                     NYD-SP30; tubulin--tyrosine ligase-like protein 7; tubulin
                     tyrosine ligase-like family, member 7"
                     /codon_start=1
                     /product="tubulin polyglutamylase TTLL7 isoform 1"
                     /protein_id="NP_078962.4"
                     /db_xref="CCDS:CCDS690.2"
                     /db_xref="GeneID:79739"
                     /db_xref="HGNC:HGNC:26242"
                     /db_xref="MIM:618813"
                     /translation="MPSLPQEGVIQGPSPLDLNTELPYQSTMKRKVRKKKKKGTITAN
                     VAGTKFEIVRLVIDEMGFMKTPDEDETSNLIWCDSAVQQEKISELQNYQRINHFPGMG
                     EICRKDFLARNMTKMIKSRPLDYTFVPRTWIFPAEYTQFQNYVKELKKKRKQKTFIVK
                     PANGAMGHGISLIRNGDKLPSQDHLIVQEYIEKPFLMEGYKFDLRIYILVTSCDPLKI
                     FLYHDGLVRMGTEKYIPPNESNLTQLYMHLTNYSVNKHNEHFERDETENKGSKRSIKW
                     FTEFLQANQHDVAKFWSDISELVVKTLIVAEPHVLHAYRMCRPGQPPGSESVCFEVLG
                     FDILLDRKLKPWLLEINRAPSFGTDQKIDYDVKRGVLLNALKLLNIRTSDKRRNLAKQ
                     KAEAQRRLYGQNSIKRLLPGSSDWEQQRHQLERRKEELKERLAQVRKQISREEHENRH
                     MGNYRRIYPPEDKALLEKYENLLAVAFQTFLSGRAASFQRELNNPLKRMKEEDILDLL
                     EQCEIDDEKLMGKTTKTRGPKPLCSMPESTEIMKRPKYCSSDSSYDSSSSSSESDENE
                     KEEYQNKKREKQVTYNLKPSNHYKLIQQPSSIRRSVSCPRSISAQSPSSGDTRPFSAQ
                     QMISVSRPTSASRSHSLNRASSYMRHLPHSNDACSTNSQVSESLRQLKTKEQEDDLTS
                     QTLFVLKDMKIRFPGKSDAESELLIEDIIDNWKYHKTKVASYWLIKLDSVKQRKVLDI
                     VKTSIRTVLPRIWKVPDVEEVNLYRIFNRVFNRLLWSRGQGLWNCFCDSGSSWESIFN
                     KSPEVVTPLQLQCCQRLVELCKQCLLVVYKYATDKRGSLSGIGPDWGNSRYLLPGSTQ
                     FFLRTPTYNLKYNSPGMTRSNVLFTSRYGHL"
     exon            404..535
                     /gene="TTLL7"
                     /inference="alignment:Splign:2.1.0"
     exon            536..657
                     /gene="TTLL7"
                     /inference="alignment:Splign:2.1.0"
     exon            658..725
                     /gene="TTLL7"
                     /inference="alignment:Splign:2.1.0"
     exon            726..884
                     /gene="TTLL7"
                     /inference="alignment:Splign:2.1.0"
     exon            885..1101
                     /gene="TTLL7"
                     /inference="alignment:Splign:2.1.0"
     exon            1102..1266
                     /gene="TTLL7"
                     /inference="alignment:Splign:2.1.0"
     exon            1267..1425
                     /gene="TTLL7"
                     /inference="alignment:Splign:2.1.0"
     exon            1426..1520
                     /gene="TTLL7"
                     /inference="alignment:Splign:2.1.0"
     exon            1521..1668
                     /gene="TTLL7"
                     /inference="alignment:Splign:2.1.0"
     exon            1669..1742
                     /gene="TTLL7"
                     /inference="alignment:Splign:2.1.0"
     exon            1743..1878
                     /gene="TTLL7"
                     /inference="alignment:Splign:2.1.0"
     exon            1879..1965
                     /gene="TTLL7"
                     /inference="alignment:Splign:2.1.0"
     exon            1966..2164
                     /gene="TTLL7"
                     /inference="alignment:Splign:2.1.0"
     exon            2165..2370
                     /gene="TTLL7"
                     /inference="alignment:Splign:2.1.0"
     exon            2371..2505
                     /gene="TTLL7"
                     /inference="alignment:Splign:2.1.0"
     exon            2506..2586
                     /gene="TTLL7"
                     /inference="alignment:Splign:2.1.0"
     exon            2587..2747
                     /gene="TTLL7"
                     /inference="alignment:Splign:2.1.0"
     exon            2748..2921
                     /gene="TTLL7"
                     /inference="alignment:Splign:2.1.0"
     exon            2922..7980
                     /gene="TTLL7"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7259..7264
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TTLL7"
                     /note="hexamer: CATAAA"
     polyA_site      7281
                     /gene="TTLL7"
                     /note="major polyA site"
     regulatory      7953..7958
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TTLL7"
                     /note="hexamer: AATAAA"
     polyA_site      7980
                     /gene="TTLL7"
ORIGIN      
        1 gttccaggca ctccgcgtcg agcaccggag tcccgagccg tggctgccac gggcggtggg
       61 cgggcggagg agagcaccgg accaccagtg caggctgccg agtcggggcg gccgcccacg
      121 gggaagctgc gaggcgcggg agcacctggg ggaccgcttg cagcggggac gcgaggaccc
      181 gggctgggct ttcctcaccc gggtaccttg ttatcccata actttggtat cctgaaatct
      241 gaggattcca ccaagataat atgataagaa ctttcagtga tttggggcca tatcctactt
      301 agactaatgt ggaatttcca gatttcctga gagcttggta cagcagcaca cactgcttgc
      361 taatcagcac aggcaataat gccatctctg cctcaagaag gagttattca gggaccctct
      421 cccctggatt tgaatacaga attaccttat caaagcacaa tgaaaaggaa agtcagaaag
      481 aagaaaaaga agggaaccat tacagcaaat gttgccggga caaagtttga aattgttcgt
      541 ttagtaatag atgaaatggg atttatgaaa actccagatg aggatgaaac aagtaatctt
      601 atatggtgtg attctgctgt tcagcaggag aaaatttcag agctgcaaaa ttatcagagg
      661 atcaaccatt ttccaggaat gggggagatc tgtaggaagg atttcttagc aagaaatatg
      721 accaaaatga tcaagtctcg gcctctggat tatacctttg ttcctcgaac ttggatcttt
      781 cctgctgaat atactcaatt ccaaaattat gtgaaagaat tgaagaaaaa acggaagcag
      841 aaaactttta tagtgaaacc agctaatggt gcaatgggtc atgggatttc tttgataaga
      901 aatggtgaca aacttccatc tcaggatcat ttgattgttc aagaatacat tgaaaagcct
      961 ttcctaatgg aaggttacaa gtttgactta cgaatttata ttctggttac atcgtgtgat
     1021 ccactaaaaa tatttctcta ccatgatggg cttgtgcgaa tgggtacaga gaagtacatt
     1081 ccacctaatg agtccaattt gacccagtta tacatgcatc tgacaaacta ctccgtgaac
     1141 aagcataatg agcattttga acgggatgaa actgagaaca aaggcagcaa acgttccatc
     1201 aaatggttta cagaattcct tcaagcaaat caacatgatg ttgctaagtt ttggagtgat
     1261 atttcagaat tggtggtaaa gaccctgatt gtagcagaac ctcatgtcct gcatgcctat
     1321 cgaatgtgta gacctggtca acctccagga agcgaaagtg tctgctttga agtcctggga
     1381 tttgatattt tgttggatag aaaactaaag ccatggcttc tggagattaa ccgagcccca
     1441 agctttggaa ctgatcagaa aatagactat gatgtaaaaa ggggagtgct gctaaatgcg
     1501 ttgaagctac taaacataag gaccagtgac aaaagaagaa acttggccaa acaaaaagct
     1561 gaggctcaaa ggaggctcta tggtcaaaat tcaattaaaa ggctcttacc aggctcctca
     1621 gactgggaac agcagagaca ccagttggag aggcggaaag aagagttgaa agagagactc
     1681 gctcaagtac gaaagcagat ctcacgagaa gaacatgaaa atcgacatat ggggaattat
     1741 agacgaattt atcctcctga agataaagca ttacttgaaa agtatgaaaa tttgttagct
     1801 gttgcctttc agaccttcct ttcaggaaga gcagcttcat tccagcgaga gttgaataat
     1861 cctttgaaaa ggatgaagga agaagatatt ttggatcttc tggagcaatg tgaaattgat
     1921 gatgaaaagt tgatgggaaa aactaccaag actcgaggac caaagcctct gtgttctatg
     1981 cctgagagta ctgagataat gaaaagacca aagtactgca gcagtgacag cagttatgat
     2041 agtagcagca gctcttcaga atctgacgaa aatgaaaaag aagagtacca aaataagaaa
     2101 agagaaaagc aagttacata taatcttaaa ccctccaacc actacaaatt aattcaacaa
     2161 cccagctcca taagacgttc agtcagctgc cctcggtcca tctctgctca atcaccttcc
     2221 agtggggaca cccgcccatt ttctgctcaa caaatgatat ctgtgtcacg gccaacttct
     2281 gcatctcggt cacattcctt aaaccgtgct tcctcctaca tgaggcatct gcctcacagt
     2341 aatgatgcct gctctaccaa ctctcaagtg agtgagtctt tgcggcaact gaaaacaaaa
     2401 gaacaagaag atgatctaac aagtcagacc ttatttgttc tcaaagacat gaagatccgg
     2461 tttccaggaa agtcagatgc agaatcagaa cttctgatag aagatatcat tgataactgg
     2521 aagtatcata aaaccaaagt ggcttcatat tggctcataa aattggactc tgtaaaacaa
     2581 cgaaaagttt tggacatagt gaaaacaagt attcgtacag ttcttccacg catctggaag
     2641 gtgcctgatg ttgaagaagt aaatttatat cggattttca accgggtttt taatcgctta
     2701 ctctggagtc gtggccaagg gctgtggaac tgtttctgtg attcaggatc ctcttgggag
     2761 agtatattca ataaaagccc ggaggtggtg actcctttgc agctccagtg ttgccagcgc
     2821 ctagtggagc tttgtaaaca gtgcctgcta gtggtttaca aatatgcaac tgacaaaaga
     2881 ggatcacttt caggcattgg tcctgactgg ggtaattcca ggtatttact accagggagc
     2941 acccaattct tcttgagaac accaacctac aacttgaagt acaattcacc tggaatgact
     3001 cgctccaatg ttttgtttac atccagatat ggccatctgt gaaacagaag ggaagatcgc
     3061 cattggttat acataacagc aattcatttt tttcctctga agttgaacat gcaaagaaca
     3121 tgaccattaa gtgctgtttt atgtatataa gacatatata tgtgtgaaaa tatatgcaca
     3181 tatgcaccct aataacatat atttattata ttaaatgata tatgaaagaa gaattagcag
     3241 aaaatggaat ataagactta acctttctgg aaacgtaata aaccatgtta aaattgttta
     3301 cacaaatatg tgaatgtcta gaatctgcta ggtttataat taattccttc ctactagaaa
     3361 tgttattttt gctgcagagt atataaaaca aattgatctt gaagatccaa ttacagtgtt
     3421 aaattatttt ctagataaca tgccttttga cctgaaaaag ggtttagtat aataccttaa
     3481 aaattctcat atatagtagc cattttaaat gaaacaaaaa gatttagaag cctggtgttg
     3541 cttgatgata agattaagaa gtttaaaacg ggtttatcat tactatagca cactgtaaag
     3601 tgctagaaaa gtcataacct gattctccaa tctttttatt cctctatgtg gaaatttagc
     3661 tacttgtaat aaggtacatt ttcagtaagg atctggtgag atcatattat gatctaacat
     3721 gaaagacagg ctgggcgcgg tggctcacgc ctgtaattcc agcactttgg gaggccgagg
     3781 tgagtggatc accgctggtc aggagtttga gactagcctg gccaacatgg tgaaacccca
     3841 tctctactaa aaatacaaaa attagctggg cgtgatggta agtgcttgta atcccagcta
     3901 cttgggcggc tgagacagga gaatcacttg aacctgggag gcggaggttg cagtgagccg
     3961 agattgtgcc attgcattct agcctgggtg acaagagtga aactctgtct caaaaaaaaa
     4021 aaataataat aaaataaaat aaataaataa ataaaaagaa gataaaaata aataaataaa
     4081 atggaagaca atccaatggg ttaaaaataa aatgtaaact agctttcatt tttacttttc
     4141 ataatcacat aaaggaacag aaaatgatgg taacaaaatc tttctatatg gcttttatgt
     4201 cttataccac tcatttttat ttggaaagta tatctttgat gggtttaaca tgtggttaaa
     4261 tacaatttct cctgtttcgc agaagtagaa gagttgacac atttcactca ttttagtgtt
     4321 acaggataat gagacaaact tatttttata aatctctcaa ggttgaaatc aacttatatt
     4381 gcaaattcta atacagtagt ttctcattgc accacagaaa cagttaaagg attgtgaata
     4441 gaagatttca attatcacat attacaagtc atcagtgtac ccttgagggt ttttaaaaaa
     4501 tcaaaacaga gaacgaagtg ttcttgtcca aagttgttat gcataagttt catagcagtt
     4561 tacttccttt tcttgaatac agtttttaaa accaagagtg agctttcagt tttccataaa
     4621 aatataagcc gtactacttt gacattgaaa tcatcagtgc agccatcact tcttagaatt
     4681 tatttaaact tcttctccca acagttttat tttcttttag ctgctaatta ttttcgaaat
     4741 tcatgaatgt tttacctcct tttactattc tgaaagttat ttcaagaagt ggccccaaag
     4801 caggagaact gagaggggca aattggcctg gtttaattca cagcctgaag aattggcaac
     4861 ctaaagttat aagttagatg tattttgctt ttcaagccat cttctgagcc ttttttaggc
     4921 tgaaatgatt tgtttatttc ccaaattatt gctagctact tgatttttta tggctaccta
     4981 acatccacat ttggtagata cttttcctct ctgcatgcat cccaaagaag aatttgctat
     5041 ttgtggaaga agagaataag ggtatcagaa tgaaggaaat tacagtgact acactgttta
     5101 tgactccatt ttgtgaattc ttaaatatgc tatggatttt tttttagaaa aaataatgca
     5161 aaaattggga tattacagaa tcaccataaa gatgatcaac aagtaataag tcttttcatg
     5221 gagttcattt ttcttttaaa ttcatgattt ggccacaaaa atatatatat aagtgtctga
     5281 tatatgataa cagcccagtt tctcggccac tcatttgcat tatcttaaat cacaaataat
     5341 tacttaattt gctggagtgt gtgctttgca acttttgtac cagagcaaaa tttgtattta
     5401 aaacaaaaaa taagaatgcc catcactagg agaaacactc ctcacagaaa acacacacac
     5461 acacacacac acaatttaaa aactgagtaa atttaaatgt atgaaagtac cccacaaatt
     5521 gatttcaaca aataaatttc atttctctag ctacttatgt ctggccttat tttgagcgtt
     5581 acaattttat tgccttcatt tgcctattta gactgatgta gtttgatatg atgaagttgt
     5641 gaataaaagc cttgtgttca ttatttatat atactacctg gtatgctatg gactgtgtct
     5701 gctgtagtgc tattccctaa tgagcaacta agagaagaca caacaataaa ccatggaagt
     5761 gttgggaggc catggaaatg atttagaggt ataaaatatt cccaagtttt tattataaat
     5821 ttttattcat aggttaaaac atataagcat aagtgattgt acaggtgtga ctcccttttc
     5881 taggagagaa aatagcttta tttgaaaact ccaaaagcta cttaatctta ccagaggttt
     5941 ttaatagggg aactgggttt acttacaatg aaagcatatt ttcattctgc tatagaaaaa
     6001 catatccctg ctcattcagt aaatctaaga ttggaatgct ttctagaact atgcaatatt
     6061 tgaataattt ctagaaatgt ctaagaaaca acctttttta ttttaaatca tcacttacaa
     6121 acgtagtctg agactgcaaa ctagttttca cttgactaat ccatcattat agattagtta
     6181 ccatttgctc tatataatct attgaagaaa ctattgttat tcatattttg attaatttta
     6241 ctagcaacaa atttttattt tagtagcatt gcatttacct taaatatgta aaaatgaagt
     6301 tgtaacagga tcaaatatgg aaatggcaat ggtaactctg cctagaacat agttgaatgt
     6361 ccttggttgt cggtaagatg caaagatcta tacaaatttt atcataggtc aaaattattt
     6421 ctaaatatac aaacagtttc aactatttct ttctccctaa aactaaaacc aaaccaaacc
     6481 caaatgaaga aacctaaact tcttttcatc taatagttat acccaactag ataatagtag
     6541 cttctagaca tcaataaaaa gatttcattt taactgtctt tttaatttgt aaaatatatg
     6601 agtatggaat tttgtatcta acttgaaatt tcagatgttt taataatcca aatacgttct
     6661 tctttagcat gtcaaagtac taatagttaa aaaatttctt tagatttaag catatacatt
     6721 acttgacttt ttcaaaagta tcaaaaaatt gatagctgca gaaatgccat tatttgattt
     6781 tctaaaaaac attgattcat tcttaaatgt gtattcttta aaaaatagta aatacctcaa
     6841 gagtgacaga aaactttcct tttctgttct gtaatgctaa tttaaacttt gagtcttagt
     6901 ttacatggtc ataggggtta aataaaatgt ataactgtac aattaattgt gttcttgtga
     6961 cctgatgatt ttttgaaaat ttgcttttct ctttaagaaa tttaagtttt caagggccgt
     7021 attagttatc taaatatttt gggctaatgt tgacttataa ataaataaaa atttagaaat
     7081 atattcatga tgacaatttt gttacttaca ctgcctattc tttatttctt ttttagttca
     7141 aaggtgaaat tttgaccttt gtattaacaa agcctcaaga aaagagaaat tctgcctttt
     7201 aaacattggt tttccttgca ttttatggtg gtgtgatttt gcctcagcaa taataaaaca
     7261 taaaatatgt tgttgcatca agttcagttt gtctgctgag attattttta agaaccaggt
     7321 tgaagcctct atgcctaaaa aagcgtttat tgtctggata catataaagc aagatatatg
     7381 gctacaaata agtcttgcaa ccaaaattgg tatattaaaa tttactgcac actttgagat
     7441 tgctgccatt ttttggtgct ttttggacct cgtcataaag ggatgtatcg tatattaggg
     7501 aaaattactc aagttacaca ttctacatta actgcgctgt attatctaca ggtacaatca
     7561 atggaccaat agttcctaaa ttagtaataa ggcttacctt acaaaagtaa tgaaataaca
     7621 ctgatatttc tctttcaaag gctaacagca attcttggtc ctgagctatt cagttcatac
     7681 aataactact gtacatgcta caacatctga atattaatgg ttttgctgca gattctgggt
     7741 atgaggatta gcttgaaagc aatacatttg ctaacatgaa tcatgactca cattatcccc
     7801 gtgtgcttta ctacctgtat atgaatgcaa atgttgttac agaaaatatg cttgaaatgt
     7861 caatacagtg tgcaattagc gttgcattgt catgctccag catgtgatat ctgtatggtg
     7921 aagttatttc aattactctg atacattact ataataaaaa agtttaacct aagaaagcta
//
