LOCUS       NM_001396017            3030 bp    mRNA    linear   PRI 23-AUG-2023
DEFINITION  Homo sapiens tubulin tyrosine ligase like 13 (TTLL13), mRNA.
ACCESSION   NM_001396017
VERSION     NM_001396017.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3030)
  AUTHORS   Janke C, Rogowski K, Wloga D, Regnard C, Kajava AV, Strub JM,
            Temurak N, van Dijk J, Boucher D, van Dorsselaer A, Suryavanshi S,
            Gaertig J and Edde B.
  TITLE     Tubulin polyglutamylase enzymes are members of the TTL domain
            protein family
  JOURNAL   Science 308 (5729), 1758-1762 (2005)
   PUBMED   15890843
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC091167.19.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA1968968,
                              SAMEA2148093 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000641754.2/ ENSP00000493387.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-253               AC091167.19        88865-89117         c
            254-521             AC091167.19        87786-88053         c
            522-562             AC091167.19        87079-87119         c
            563-681             AC091167.19        85306-85424         c
            682-812             AC091167.19        82788-82918         c
            813-969             AC091167.19        82376-82532         c
            970-1113            AC091167.19        81392-81535         c
            1114-1199           AC091167.19        80951-81036         c
            1200-1431           AC091167.19        80404-80635         c
            1432-1616           AC091167.19        79746-79930         c
            1617-1802           AC091167.19        76482-76667         c
            1803-1980           AC091167.19        76004-76181         c
            1981-2160           AC091167.19        75528-75707         c
            2161-2272           AC091167.19        74615-74726         c
            2273-3030           AC091167.19        73196-73953         c
FEATURES             Location/Qualifiers
     source          1..3030
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="15"
                     /map="15q26.1"
     gene            1..3030
                     /gene="TTLL13"
                     /gene_synonym="TTLL13P"
                     /note="tubulin tyrosine ligase like 13"
                     /db_xref="GeneID:440307"
                     /db_xref="HGNC:HGNC:32484"
                     /db_xref="MIM:620485"
     exon            1..253
                     /gene="TTLL13"
                     /gene_synonym="TTLL13P"
                     /inference="alignment:Splign:2.1.0"
     exon            254..521
                     /gene="TTLL13"
                     /gene_synonym="TTLL13P"
                     /inference="alignment:Splign:2.1.0"
     CDS             265..2520
                     /gene="TTLL13"
                     /gene_synonym="TTLL13P"
                     /note="tubulin--tyrosine ligase-like protein 13; tubulin
                     tyrosine ligase-like family, member 13; tubulin
                     polyglutamylase TTLL13P; tubulin tyrosine ligase like 13,
                     pseudogene"
                     /codon_start=1
                     /product="tubulin polyglutamylase TTLL13"
                     /protein_id="NP_001382946.1"
                     /db_xref="CCDS:CCDS92063.1"
                     /db_xref="GeneID:440307"
                     /db_xref="HGNC:HGNC:32484"
                     /db_xref="MIM:620485"
                     /translation="MEPSTCRTMESEEDYVEEKESEKCVKEGVTNPSNSSQQALLKAD
                     YKALKNGVPSPIMATKIPKKVIAPVDTGDLEAGRRKRRRKRRSLAINLTNCKYESVRR
                     AAQMCGLKEVGEDEEWTLYWTDCAVSLERVMDMKRFQKINHFPGMTEICRKDLLARNL
                     NRMYKLYPSEYNIFPRTWCLPADYGDFQSYGRQRKARTYICKPDSGCQGRGIFITRNP
                     REIKPGEHMICQQYISKPLLIDGFKFDMRVYVLITSCDPLRIFTYEEGLARFATTPYM
                     EPSHNNLDNVCMHLTNYAINKHNENFVRDGAVGSKRKLSTLNIWLQEHSYNPGELWGD
                     IEDIIIKTIISAHSVLRHNYRTCFPQYLNGGTCACFEILGFDILLDHKLKPWLLEVNH
                     SPSFTTDSCLDQEVKDALLCDAMTLVNLRGCDKRKVMEEDKRRVKERLFQCYRQPRES
                     RKEKTESSHVAMLDQERYEDSHLGKYRRIYPGPDTEKYARFFKHNGSLFQETAASKAR
                     EECARQQLEEIRLKQEQQETSGTKRQKARDQNQGESAGEKSRPRAGLQSLSTHLAYRN
                     RNWEKELLPGQLDTMRPQEIVEEEELERMKALLQRETLIRSLGIVEQLTRLQHPGPQG
                     QKKLHESRPKNFNWTGEPAAINSCSLSMKKAGRCYFSSARIRLTSQGQASRRLEAINR
                     VLAGSVPPTLTPKQGYFLQPERVASDSWTECTLPSMVNSEHRAAKVPLCPASAPMLQR
                     SRALLNINQFR"
     exon            522..562
                     /gene="TTLL13"
                     /gene_synonym="TTLL13P"
                     /inference="alignment:Splign:2.1.0"
     exon            563..681
                     /gene="TTLL13"
                     /gene_synonym="TTLL13P"
                     /inference="alignment:Splign:2.1.0"
     exon            682..812
                     /gene="TTLL13"
                     /gene_synonym="TTLL13P"
                     /inference="alignment:Splign:2.1.0"
     exon            813..969
                     /gene="TTLL13"
                     /gene_synonym="TTLL13P"
                     /inference="alignment:Splign:2.1.0"
     exon            970..1113
                     /gene="TTLL13"
                     /gene_synonym="TTLL13P"
                     /inference="alignment:Splign:2.1.0"
     exon            1114..1199
                     /gene="TTLL13"
                     /gene_synonym="TTLL13P"
                     /inference="alignment:Splign:2.1.0"
     exon            1200..1431
                     /gene="TTLL13"
                     /gene_synonym="TTLL13P"
                     /inference="alignment:Splign:2.1.0"
     exon            1432..1616
                     /gene="TTLL13"
                     /gene_synonym="TTLL13P"
                     /inference="alignment:Splign:2.1.0"
     exon            1617..1802
                     /gene="TTLL13"
                     /gene_synonym="TTLL13P"
                     /inference="alignment:Splign:2.1.0"
     exon            1803..1980
                     /gene="TTLL13"
                     /gene_synonym="TTLL13P"
                     /inference="alignment:Splign:2.1.0"
     exon            1981..2160
                     /gene="TTLL13"
                     /gene_synonym="TTLL13P"
                     /inference="alignment:Splign:2.1.0"
     exon            2161..2272
                     /gene="TTLL13"
                     /gene_synonym="TTLL13P"
                     /inference="alignment:Splign:2.1.0"
     exon            2273..3030
                     /gene="TTLL13"
                     /gene_synonym="TTLL13P"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3010..3015
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TTLL13"
                     /gene_synonym="TTLL13P"
                     /note="hexamer: ATTAAA"
     polyA_site      3030
                     /gene="TTLL13"
                     /gene_synonym="TTLL13P"
                     /note="major polyA site"
ORIGIN      
        1 agaggaagcg ctgccccggc agccgcagcc acggccaccg ggagctagga gtgaacccct
       61 gcgggggagc agcttccccc tcgcgatcgt ggggacagcc agtcctgtga aacgaggagg
      121 cggttccgga cgcccagaaa cgcccaggga gacctggagc cgggggaaga ggggacatga
      181 gcggccagct gagtccatcc ccaggcggct aggggcggac ccagcagccc ctcagctctc
      241 ctcgtaacca cggaatctga gagaatggag ccgagtacct gtaggaccat ggaatcagag
      301 gaagactatg ttgaggaaaa ggaatctgag aagtgtgtta aagagggagt taccaacccc
      361 tctaactctt cacagcaggc tctcttaaaa gctgactata aggcattaaa aaatggggtt
      421 ccctcaccca ttatggccac aaaaattccg aagaaagtca tagccccagt tgacacaggc
      481 gacttagaag ctgggaggag gaagagaagg cggaaacgca gatcactggc catcaacctg
      541 accaactgca agtatgagag tgtgcgtcgg gcagcccaaa tgtgtggcct gaaggaggtg
      601 ggggaggatg aagagtggac tctgtactgg acagactgcg ctgtctcact ggaacgagtc
      661 atggacatga agaggtttca gaaaatcaac cacttccctg gcatgacaga aatctgccgc
      721 aaagatctgc tggctcggaa cctcaaccgc atgtacaaac tctatccctc tgagtacaac
      781 atcttccccc gcacctggtg cctccccgca gactatgggg acttccagtc ctacggtcgt
      841 cagcgaaaag cccgcacata tatctgcaag ccagacagtg gctgtcaggg acgtggcatc
      901 ttcattaccc gaaatccccg ggagatcaag ccaggagagc atatgatctg ccagcaatac
      961 atctccaagc ccctcctcat tgatggcttc aagtttgata tgcgagtcta cgtcctgatc
     1021 acatcctgtg accctctccg gatcttcaca tatgaggagg gcctagcccg ttttgccacc
     1081 acgccctata tggagcccag ccataacaac ctggacaatg tctgcatgca cctgaccaac
     1141 tatgctatca acaaacacaa tgagaatttt gtccgggatg gcgctgtggg cagtaagagg
     1201 aagctgtcga cactcaacat ctggctgcaa gagcacagct acaaccctgg agagctgtgg
     1261 ggggacatcg aggacatcat catcaaaacc atcatctcag cccattctgt tctacgccac
     1321 aactaccgaa cctgttttcc ccagtatctg aatggaggta catgtgcctg ttttgaaatc
     1381 cttggttttg acatcttgct ggaccacaag ttgaagccct ggctgctaga ggtaaaccac
     1441 tctccaagct ttaccacgga ctcatgcctt gatcaagaag taaaggatgc acttctctgt
     1501 gatgctatga cccttgtcaa cctccggggc tgtgacaaaa ggaaggtgat ggaggaggat
     1561 aagcggcgag tcaaggaacg gcttttccag tgctaccgac agccacgaga atctaggaaa
     1621 gaaaaaactg agtcatccca tgtggcaatg ctggaccagg aacgatatga ggattctcac
     1681 ctgggaaaat accggcggat ctaccctggg cctgacacag agaagtatgc ccgcttcttc
     1741 aagcacaatg gctccctctt ccaagagact gctgcttcca aggccagaga ggagtgtgcc
     1801 aggcagcaac tagaggagat ccgccttaag caggaacagc aggagacctc gggcactaag
     1861 aggcaaaagg ccagggacca gaaccagggt gaatcagctg gggagaaaag ccgacccagg
     1921 gcagggctcc agagcctttc cacccacttg gcttacagga accgcaactg ggagaaagag
     1981 ctgctgccgg gacagctgga caccatgagg cctcaagaaa ttgtggaaga ggaggagctg
     2041 gagcggatga aggccctgct acaaagggag actctcatcc gaagcctggg tattgtagag
     2101 cagctcaccc gtctgcagca ccctggcccc cagggccaga aaaaacttca tgagagtcgg
     2161 cccaagaact tcaactggac aggagagccg gcagccatca actcctgttc attgtcaatg
     2221 aagaaggctg ggaggtgcta tttttccagt gccagaatca ggctcactag ccaaggacaa
     2281 gccagcagaa ggctagaagc cataaaccga gtcctggcag gatcagtgcc acccacttta
     2341 accccaaagc agggctattt tctgcaaccg gaaagagtgg catctgactc atggactgaa
     2401 tgcaccttgc cctccatggt aaactctgaa cacagagcag ccaaggttcc cctctgccct
     2461 gcgtctgcac ccatgctgca gcgttccaga gcactcctca acatcaatca gttcaggtaa
     2521 aagcaggagg gaagcactct acctctcctg gataacctcc ccaggtttcc aaagggcatt
     2581 aaatctttgc taaatgaatg actgccacca agttccactt tgaaaagccc tgcccaggaa
     2641 ccccatttgt ataaggcaaa atacaaagac accaagaatt cctcaatacc ctaagattaa
     2701 ttggggatcg gtaaagacta gaagatgaag aggcgccaag gccagccatg tactcatttc
     2761 tgctcatcaa gccttagcct gggtttatcg ctaggtgatg ggtctgaacc ctaggtgcgg
     2821 cccggggctg gaggccatcc aggagacaat gagccccttt cccagagaag ccgagtgccc
     2881 aaggcactgg gctgtcgccg tcagaagact gccgagcgga agccctgccc accgaggtgg
     2941 cggagacagg caggcctggg cagccgctgg ggcggaggga cggctcttgg aaacggaatc
     3001 cgtactttaa ttaaagttta tgcagttttc
//
