LOCUS       XM_047432155            4215 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens transcription termination factor 2 (TTF2),
            transcript variant X13, mRNA.
ACCESSION   XM_047432155
VERSION     XM_047432155.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4215
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..4215
                     /gene="TTF2"
                     /gene_synonym="F2; HuF2; ZGRF6"
                     /note="transcription termination factor 2; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 39 ESTs, 592 long SRA reads, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     74 samples with support for all annotated introns"
                     /db_xref="GeneID:8458"
                     /db_xref="HGNC:HGNC:12398"
                     /db_xref="MIM:604718"
     CDS             22..3507
                     /gene="TTF2"
                     /gene_synonym="F2; HuF2; ZGRF6"
                     /codon_start=1
                     /product="transcription termination factor 2 isoform X8"
                     /protein_id="XP_047288111.1"
                     /db_xref="GeneID:8458"
                     /db_xref="HGNC:HGNC:12398"
                     /db_xref="MIM:604718"
                     /translation="MEEVRCPEHGTFCFLKTGVRDGPNKGKSFYVCRADTCSFVRATD
                     IPVSHCLLHEDFVVELQGLLLPQDKKEYRLFFRCIRSKAEGKRWCGSIPWQDPDSKEH
                     SVSNKSQHASETFHHSSNWLRNPFKVLDKNQEPALWKQLIKGEGEEKKADKKQREKGD
                     QLFDQKKEQKPEMMEKDLSSGLVPKKKQSVVQEKKQEEGAEIQCEAETGGTHKRDFSE
                     IKSQQCQGNELTRPSASSQEKSSGKSQDVQRESEPLREKVTQLLPQNVHSHNSISKPQ
                     KGGPLNKEYTNWEAKETKAKDGPSIQATQKSLPQGHFQERPETHSVPAPGGPAAQAAP
                     AAPGLSLGEGREAATSSDDEEEDDVVFVSSKPGSPLLFDSTLDLETKENLQFPDRSVQ
                     RKVSPASGVSKKVEPSDPVARRVYLTTQLKQKKSTLASVNIQALPDKGQKLIKQIQEL
                     EEVLSGLTLSPEQGTNEKSNSQVPQQSHFTKTTTGPPHLVPPQPLPRRGTQPVGSLEL
                     KSACQVTAGGSSQCYRGHTNQDHVHAVWKITSEAIGQLHRSLESCPGETVVAEDPAGL
                     KVPLLLHQKQALAWLLWRESQKPQGGILDDMGLGKTLTMIALILTQKNQEKKEEKEKS
                     TALTWLSKDDSCDFTSHGTLIICPASLIHHWKNEVEKRVNSNKLRVYLYHGPNRDSRA
                     RVLSTYDIVITTYSLVAKEIPTNKQEAEIPGANLNVEGTSTPLLRIAWARIILDEAHN
                     VKNPRVQTSIAVCKLQACARWAVTGTPIQNNLLDMYSLLKFLRCSPFDEFNLWRSQVD
                     NGSKKGGERLSILTKSLLLRRTKDQLDSTGRPLVILPQRKFQLHHLKLSEDEETVYNV
                     FFARSRSALQSYLKRHESRGNQSGRSPNNPFSRVALEFGSEEPRHSEAADSPRSSTVH
                     ILSQLLRLRQCCCHLSLLKSALDPMELKGEGLVLSLEEQLSALTLSELRDSEPSSTVS
                     LNGTFFKMELFEGMRESTKISSLLAELEAIQRNSASQKSVIVSQWTNMLKVVALHLKK
                     HGLTYATIDGSVNPKQRMDLVEAFNHSRGPQVMLISLLAGGVGLNLTGGNHLFLLDMH
                     WNPSLEDQACDRIYRVGQQKDVVIHRFVCEGTVEEKILQLQEKKKDLAKQVLSGSGES
                     VTKLTLADLRVLFGI"
     polyA_site      4215
                     /gene="TTF2"
                     /gene_synonym="F2; HuF2; ZGRF6"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 gaacttgggg gacccagcga aatggaagaa gttaggtgtc cagagcacgg gactttctgc
       61 tttcttaaga ccggcgtccg cgatggcccg aataaaggaa agagcttcta cgtgtgccgg
      121 gcagacacgt gcagcttcgt gcgggccacc gacattcctg tttcccattg cttattgcat
      181 gaggactttg tggtagagct tcagggtttg cttctgccac aggacaagaa agaatacaga
      241 ttgttcttcc gatgcattag aagtaaggca gaggggaaac gctggtgtgg aagtattcca
      301 tggcaggatc ctgattccaa agaacattct gtatccaata agtctcagca tgcatctgag
      361 acatttcatc attcttccaa ctggctgaga aatccattca aggtacttga caagaatcaa
      421 gaaccagctc tctggaaaca gctcatcaaa ggtgaaggtg aggaaaagaa ggctgataag
      481 aagcaaagag aaaagggaga tcagcttttc gatcaaaaga aagaacagaa gcctgaaatg
      541 atggagaaag acctctcatc tggcctggta ccaaagaaaa aacaatctgt agttcaagag
      601 aagaagcaag aagagggagc agagattcag tgtgaggcag agactggagg cacacacaaa
      661 agagactttt ctgaaattaa atctcaacag tgccaaggta atgagcttac aagaccatct
      721 gcatcttctc aggagaaatc aagtggtaag agtcaagatg tccaaagaga atcagaacct
      781 ctgagagaaa aggttaccca gcttttgcct caaaatgttc acagtcacaa ctcaataagc
      841 aagccccaga aagggggacc cctcaacaag gagtacacga actgggaggc taaagaaaca
      901 aaggcaaagg atggccctag catacaggcc acccagaaaa gcctgcctca ggggcatttc
      961 caagagcggc cggagaccca cagtgtgcct gctcctggag gaccagcggc tcaggctgca
     1021 ccagcagcac cagggctttc cctgggtgag ggccgtgaag ctgccacaag cagtgacgac
     1081 gaggaggaag atgatgttgt ttttgtttcc tctaagcctg ggagccccct actctttgac
     1141 tcgactctgg acttagagac gaaggaaaac ctccaattcc ctgatcgaag tgtgcaaaga
     1201 aaggtgtctc ctgcctcagg tgtttccaag aaggtagaac cctcagaccc agtagcccgg
     1261 cgtgtctacc ttacaacaca actgaaacaa aagaagagca cactggcatc agtgaacatc
     1321 caggctcttc cagacaaggg tcagaagttg atcaaacaaa tccaggagct ggaggaagta
     1381 ctcagtggtc ttaccctttc cccagagcaa ggaactaatg agaagagtaa cagtcaagta
     1441 ccacagcaga gtcacttcac caaaactacc actggccctc cccacctggt gcctccccaa
     1501 ccccttcctc gtcgtggtac ccaacctgtg ggttctctag aactaaagtc tgcctgccag
     1561 gtgactgctg gaggatccag tcagtgctat cgaggccata caaaccaaga tcacgttcat
     1621 gcagtgtgga aaatcacaag tgaagccatc ggtcaactgc atcgctcact tgagtcatgt
     1681 cctggtgaga cggttgtggc agaagatccc gccgggctga aggtcccttt gctactacac
     1741 cagaagcagg cattggcttg gttactatgg cgagaaagtc agaagccaca aggaggaatt
     1801 ctggatgata tgggcttagg aaaaaccctg acaatgattg cgctcatcct gacccagaag
     1861 aatcaagaga aaaaggaaga aaaggagaaa agcacagctt tgacgtggct ctccaaagat
     1921 gactcttgtg actttacttc ccatggaaca ctaatcatct gtcctgcctc cctgatccat
     1981 cattggaaaa atgaggtgga gaaacgggtg aacagcaaca aactaagagt ctatctctac
     2041 catgggccaa accgggattc acgtgccaga gtcctctcta catatgacat cgtgatcact
     2101 acctatagcc tcgtggccaa ggagattccc acaaacaagc aagaggcaga gatcccaggt
     2161 gcaaacctca atgtggaggg cacctcaaca cctttgcttc gaatagcctg ggctcgaatc
     2221 atattggatg aagctcacaa tgttaagaat ccccgagtgc agacttccat agctgtgtgt
     2281 aagctacaag cctgtgcccg ttgggctgtc actggaaccc ccattcaaaa caacttattg
     2341 gatatgtatt cgctgctgaa gtttctccgt tgctctccat ttgatgagtt caatctgtgg
     2401 aggagtcagg ttgacaatgg ctcaaagaaa ggaggagaac ggttaagtat tttaaccaag
     2461 agccttttgc tgaggagaac aaaagaccag ctggactcta ctggcagacc tttggtgata
     2521 ctgccccagc gtaaatttca gttgcaccat ttaaagcttt ctgaagatga agagactgtt
     2581 tacaatgtgt tttttgcaag atcaaggtca gctctgcaat cctatctaaa aagacatgaa
     2641 agtagaggca accaatctgg aagaagccct aataatccat tcagtagagt ggcactggag
     2701 tttgggtctg aggagcctag acactcggag gcagcagact caccgagatc cagcaccgtc
     2761 cacatactgt cccagttgct gagactccgc cagtgttgct gtcatctttc tttactgaag
     2821 tcggccctgg atccaatgga actgaagggt gaaggtcttg tcctttccct ggaagaacag
     2881 ctcagtgctt tgaccttgtc agaactccgt gactcagagc catcttccac tgtttccctt
     2941 aacggcacct tcttcaagat ggagcttttt gaaggcatgc gagagagcac caagatttca
     3001 tctctgttgg cagaattgga ggcaattcaa agaaattcag catcccaaaa gagtgtcatt
     3061 gtctctcagt ggaccaacat gctgaaagtt gtagcattgc acctgaagaa gcatggactg
     3121 acttatgcca ccatcgatgg ctctgtcaat cccaagcaga gaatggactt ggtagaggca
     3181 tttaaccact ccagaggccc tcaggtaatg ctaatctctc tcttggccgg aggtgttggt
     3241 ctaaacctga ctggaggaaa tcacctcttt cttttggaca tgcactggaa tccatcactt
     3301 gaagatcaag cttgtgaccg aatttaccga gtagggcagc agaaagatgt tgtcatacac
     3361 agatttgttt gtgagggaac agtagaagaa aagatcttac agctccaaga aaaaaagaaa
     3421 gatttggcca aacaagttct atcagggtct ggagaatctg tcaccaagct caccttggct
     3481 gacctcagag tcctttttgg catctaacct cctgtggata agggctcaga atagcaccat
     3541 tgctgctgat gatgggagaa ccagttacta ccttctctaa cacaggctcc atcctatctc
     3601 ttcatctctt cttgccagtg atgttgcacc tgtaaccatc tttttatggg tggagcagag
     3661 agtcaatccc tgcagccacc ctgcagccag ccatctctgc agttctctca gtgcaggcag
     3721 ttcttcctct caggctgaag atcaaggaga tgctttgtac atgaacagat gctgagtatc
     3781 tgttatcatt gtattgttta gtgtcagtgt atcatttagt atttgtatca ctgtaccatt
     3841 tagtgttgta tatcactcag tcatttaata ttggttatca ccatacagtt taatatttgt
     3901 atcatttggt tcattgtatc gtttagtatt tctattataa catttctatt tgtagtattt
     3961 gtataatatt tgtgtcattt ttaatagtat ttgtattttt acaaatttgc agtatttgta
     4021 gcatttagta tcattgtttc atttagtatt tggtacaatc taataaatac taatccagtc
     4081 caatactaat ccaatccaat actaataata ctattggtac aatccaatac taataatact
     4141 attggtacaa tccaatacta ataatactaa cagtagtatt gatacaatct aataaataat
     4201 gtgtttgaca gtgta
//
