LOCUS       XM_047432144            4236 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens transcription termination factor 2 (TTF2),
            transcript variant X9, mRNA.
ACCESSION   XM_047432144
VERSION     XM_047432144.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4236
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..4236
                     /gene="TTF2"
                     /gene_synonym="F2; HuF2; ZGRF6"
                     /note="transcription termination factor 2; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 28 ESTs, 471 long SRA reads, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     41 samples with support for all annotated introns"
                     /db_xref="GeneID:8458"
                     /db_xref="HGNC:HGNC:12398"
                     /db_xref="MIM:604718"
     CDS             22..3528
                     /gene="TTF2"
                     /gene_synonym="F2; HuF2; ZGRF6"
                     /codon_start=1
                     /product="transcription termination factor 2 isoform X6"
                     /protein_id="XP_047288100.1"
                     /db_xref="GeneID:8458"
                     /db_xref="HGNC:HGNC:12398"
                     /db_xref="MIM:604718"
                     /translation="MEEVRCPEHGTFCFLKTGVRDGPNKGKSFYVCRADTCSFVRATD
                     IPVSHCLLHEDFVVELQGLLLPQDKKEYRLFFRCIRSKAEGKRWCGSIPWQDPDSKEH
                     SVSNKSQHASETFHHSSNWLRNPFKVLDKNQEPALWKQLIKGEGEEKKADKKQREKGD
                     QLFDQKKEQKPEMMEKDLSSGLVPKKKQSVVQEKKQEEGAEIQCEAETGGTHKRDFSE
                     IKSQQCQGNELTRPSASSQEKSSGKSQDVQRESEPLREKVTQLLPQNVHSHNSISKPQ
                     KGGPLNKEYTNWEAKETKAKDGPSIQATQKSLPQGHFQERPETHSVPAPGGPAAQAAP
                     AAPGLSLGEGREAATSSDDEEEDDVVFVSSKPGSPLLFDSTLDLETKENLQFPDRSVQ
                     RKVSPASGVSKKVEPSDPVARRVYLTTQLKQKKSTLASVNIQALPDKGQKLIKQIQEL
                     EEVLSGLTLSPEQGTNEKSNSQVPQQSHFTKTTTGPPHLVPPQPLPRRGTQPVGSLEL
                     KSACQVTAGGSSQCYRGNTYLYAGHTNQDHVHAVWKITSEAIGQLHRSLESCPGETVV
                     AEDPAGLKVPLLLHQKQALAWLLWRESQKPQGGILDDMGLGKTLTMIALILTQKNQEK
                     KEEKEKSTALTWLSKDDSCDFTSHGTLIICPASLIHHWKNEVEKRVNSNKLRVYLYHG
                     PNRDSRARVLSTYDIVITTYSLVAKEIPTNKQEAEIPGANLNVEGTSTPLLRIAWARI
                     ILDEAHNVKNPRVQTSIAVCKLQACARWAVTGTPIQNNLLDMYSLLKFLRCSPFDEFN
                     LWRSQVDNGSKKGGERLSILTKSLLLRRTKDQLDSTGRPLVILPQRKFQLHHLKLSED
                     EETVYNVFFARSRSALQSYLKRHESRGNQSGRSPNNPFSRVALEFGSEEPRHSEAADS
                     PRSSTVHILSQLLRLRQCCCHLSLLKSALDPMELKGEGLVLSLEEQLSALTLSELRDS
                     EPSSTVSLNGTFFKMELFEGMRESTKISSLLAELEAIQRNSASQKSVIVSQWTNMLKV
                     VALHLKKHGLTYATIDGSVNPKQRMDLVEAFNHSRGPQVMLISLLAGGVGLNLTGGNH
                     LFLLDMHWNPSLEDQACDRIYRVGQQKDVVIHRFVCEGTVEEKILQLQEKKKDLAKQV
                     LSGSGESVTKLTLADLRVLFGI"
     polyA_site      4236
                     /gene="TTF2"
                     /gene_synonym="F2; HuF2; ZGRF6"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 gaacttgggg gacccagcga aatggaagaa gttaggtgtc cagagcacgg gactttctgc
       61 tttcttaaga ccggcgtccg cgatggcccg aataaaggaa agagcttcta cgtgtgccgg
      121 gcagacacgt gcagcttcgt gcgggccacc gacattcctg tttcccattg cttattgcat
      181 gaggactttg tggtagagct tcagggtttg cttctgccac aggacaagaa agaatacaga
      241 ttgttcttcc gatgcattag aagtaaggca gaggggaaac gctggtgtgg aagtattcca
      301 tggcaggatc ctgattccaa agaacattct gtatccaata agtctcagca tgcatctgag
      361 acatttcatc attcttccaa ctggctgaga aatccattca aggtacttga caagaatcaa
      421 gaaccagctc tctggaaaca gctcatcaaa ggtgaaggtg aggaaaagaa ggctgataag
      481 aagcaaagag aaaagggaga tcagcttttc gatcaaaaga aagaacagaa gcctgaaatg
      541 atggagaaag acctctcatc tggcctggta ccaaagaaaa aacaatctgt agttcaagag
      601 aagaagcaag aagagggagc agagattcag tgtgaggcag agactggagg cacacacaaa
      661 agagactttt ctgaaattaa atctcaacag tgccaaggta atgagcttac aagaccatct
      721 gcatcttctc aggagaaatc aagtggtaag agtcaagatg tccaaagaga atcagaacct
      781 ctgagagaaa aggttaccca gcttttgcct caaaatgttc acagtcacaa ctcaataagc
      841 aagccccaga aagggggacc cctcaacaag gagtacacga actgggaggc taaagaaaca
      901 aaggcaaagg atggccctag catacaggcc acccagaaaa gcctgcctca ggggcatttc
      961 caagagcggc cggagaccca cagtgtgcct gctcctggag gaccagcggc tcaggctgca
     1021 ccagcagcac cagggctttc cctgggtgag ggccgtgaag ctgccacaag cagtgacgac
     1081 gaggaggaag atgatgttgt ttttgtttcc tctaagcctg ggagccccct actctttgac
     1141 tcgactctgg acttagagac gaaggaaaac ctccaattcc ctgatcgaag tgtgcaaaga
     1201 aaggtgtctc ctgcctcagg tgtttccaag aaggtagaac cctcagaccc agtagcccgg
     1261 cgtgtctacc ttacaacaca actgaaacaa aagaagagca cactggcatc agtgaacatc
     1321 caggctcttc cagacaaggg tcagaagttg atcaaacaaa tccaggagct ggaggaagta
     1381 ctcagtggtc ttaccctttc cccagagcaa ggaactaatg agaagagtaa cagtcaagta
     1441 ccacagcaga gtcacttcac caaaactacc actggccctc cccacctggt gcctccccaa
     1501 ccccttcctc gtcgtggtac ccaacctgtg ggttctctag aactaaagtc tgcctgccag
     1561 gtgactgctg gaggatccag tcagtgctat cgaggtaaca cctatttgta tgcaggccat
     1621 acaaaccaag atcacgttca tgcagtgtgg aaaatcacaa gtgaagccat cggtcaactg
     1681 catcgctcac ttgagtcatg tcctggtgag acggttgtgg cagaagatcc cgccgggctg
     1741 aaggtccctt tgctactaca ccagaagcag gcattggctt ggttactatg gcgagaaagt
     1801 cagaagccac aaggaggaat tctggatgat atgggcttag gaaaaaccct gacaatgatt
     1861 gcgctcatcc tgacccagaa gaatcaagag aaaaaggaag aaaaggagaa aagcacagct
     1921 ttgacgtggc tctccaaaga tgactcttgt gactttactt cccatggaac actaatcatc
     1981 tgtcctgcct ccctgatcca tcattggaaa aatgaggtgg agaaacgggt gaacagcaac
     2041 aaactaagag tctatctcta ccatgggcca aaccgggatt cacgtgccag agtcctctct
     2101 acatatgaca tcgtgatcac tacctatagc ctcgtggcca aggagattcc cacaaacaag
     2161 caagaggcag agatcccagg tgcaaacctc aatgtggagg gcacctcaac acctttgctt
     2221 cgaatagcct gggctcgaat catattggat gaagctcaca atgttaagaa tccccgagtg
     2281 cagacttcca tagctgtgtg taagctacaa gcctgtgccc gttgggctgt cactggaacc
     2341 cccattcaaa acaacttatt ggatatgtat tcgctgctga agtttctccg ttgctctcca
     2401 tttgatgagt tcaatctgtg gaggagtcag gttgacaatg gctcaaagaa aggaggagaa
     2461 cggttaagta ttttaaccaa gagccttttg ctgaggagaa caaaagacca gctggactct
     2521 actggcagac ctttggtgat actgccccag cgtaaatttc agttgcacca tttaaagctt
     2581 tctgaagatg aagagactgt ttacaatgtg ttttttgcaa gatcaaggtc agctctgcaa
     2641 tcctatctaa aaagacatga aagtagaggc aaccaatctg gaagaagccc taataatcca
     2701 ttcagtagag tggcactgga gtttgggtct gaggagccta gacactcgga ggcagcagac
     2761 tcaccgagat ccagcaccgt ccacatactg tcccagttgc tgagactccg ccagtgttgc
     2821 tgtcatcttt ctttactgaa gtcggccctg gatccaatgg aactgaaggg tgaaggtctt
     2881 gtcctttccc tggaagaaca gctcagtgct ttgaccttgt cagaactccg tgactcagag
     2941 ccatcttcca ctgtttccct taacggcacc ttcttcaaga tggagctttt tgaaggcatg
     3001 cgagagagca ccaagatttc atctctgttg gcagaattgg aggcaattca aagaaattca
     3061 gcatcccaaa agagtgtcat tgtctctcag tggaccaaca tgctgaaagt tgtagcattg
     3121 cacctgaaga agcatggact gacttatgcc accatcgatg gctctgtcaa tcccaagcag
     3181 agaatggact tggtagaggc atttaaccac tccagaggcc ctcaggtaat gctaatctct
     3241 ctcttggccg gaggtgttgg tctaaacctg actggaggaa atcacctctt tcttttggac
     3301 atgcactgga atccatcact tgaagatcaa gcttgtgacc gaatttaccg agtagggcag
     3361 cagaaagatg ttgtcataca cagatttgtt tgtgagggaa cagtagaaga aaagatctta
     3421 cagctccaag aaaaaaagaa agatttggcc aaacaagttc tatcagggtc tggagaatct
     3481 gtcaccaagc tcaccttggc tgacctcaga gtcctttttg gcatctaacc tcctgtggat
     3541 aagggctcag aatagcacca ttgctgctga tgatgggaga accagttact accttctcta
     3601 acacaggctc catcctatct cttcatctct tcttgccagt gatgttgcac ctgtaaccat
     3661 ctttttatgg gtggagcaga gagtcaatcc ctgcagccac cctgcagcca gccatctctg
     3721 cagttctctc agtgcaggca gttcttcctc tcaggctgaa gatcaaggag atgctttgta
     3781 catgaacaga tgctgagtat ctgttatcat tgtattgttt agtgtcagtg tatcatttag
     3841 tatttgtatc actgtaccat ttagtgttgt atatcactca gtcatttaat attggttatc
     3901 accatacagt ttaatatttg tatcatttgg ttcattgtat cgtttagtat ttctattata
     3961 acatttctat ttgtagtatt tgtataatat ttgtgtcatt tttaatagta tttgtatttt
     4021 tacaaatttg cagtatttgt agcatttagt atcattgttt catttagtat ttggtacaat
     4081 ctaataaata ctaatccagt ccaatactaa tccaatccaa tactaataat actattggta
     4141 caatccaata ctaataatac tattggtaca atccaatact aataatacta acagtagtat
     4201 tgatacaatc taataaataa tgtgtttgac agtgta
//
