LOCUS       XM_047432136            4208 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens transcription termination factor 2 (TTF2),
            transcript variant X5, mRNA.
ACCESSION   XM_047432136
VERSION     XM_047432136.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4208
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..4208
                     /gene="TTF2"
                     /gene_synonym="F2; HuF2; ZGRF6"
                     /note="transcription termination factor 2; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 1 mRNA, 26 ESTs, 1246 long SRA reads, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 5 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:8458"
                     /db_xref="HGNC:HGNC:12398"
                     /db_xref="MIM:604718"
     CDS             22..3573
                     /gene="TTF2"
                     /gene_synonym="F2; HuF2; ZGRF6"
                     /codon_start=1
                     /product="transcription termination factor 2 isoform X3"
                     /protein_id="XP_047288092.1"
                     /db_xref="GeneID:8458"
                     /db_xref="HGNC:HGNC:12398"
                     /db_xref="MIM:604718"
                     /translation="MEEVRCPEHGTFCFLKTGVRDGPNKGKSFYVCRADTCSFVRATD
                     IPVSHCLLHEDFVVELQGLLLPQDKKEYRLFFRCIRSKAEGKRWCGSIPWQDPDSKEH
                     SVSNKSQHASETFHHSSNWLRNPFKVLDKNQEPALWKQLIKGEGEEKKADKKQREKGD
                     QLFDQKKEQKPEMMEKDLSSGLVPKKKQSVVQEKKQEEGAEIQCEAETGGTHKRDFSE
                     IKSQQCQGNELTRPSASSQEKSSGKSQDVQRESEPLREKVTQLLPQNVHSHNSISKPQ
                     KGGPLNKEYTNWEAKETKAKDGPSIQATQKSLPQGHFQERPETHSVPAPGGPAAQAAP
                     AAPGLSLGEGREAATSSDDEEEDDVVFVSSKPGSPLLFDSTLDLETKENLQFPDRSVQ
                     RKVSPASGVSKKVEPSDPVARRVYLTTQLKQKKSTLASVNIQALPDKGQKLIKQIQEL
                     EEVLSGLTLSPEQGTNEKSNSQVPQQSHFTKTTTGPPHLVPPQPLPRRGTQPVGSLEL
                     KSACQVTAGGSSQCYRGHTNQDHVHAVWKITSEAIGQLHRSLESCPGETVVAEDPAGL
                     KVPLLLHQKQALAWLLWRESQKPQGGILADDMGLGKTLTMIALILTQKNQEKKEEKEK
                     STALTWLSKDDSCDFTSHGTLIICPASLIHHWKNEVEKRVNSNKLRVYLYHGPNRDSR
                     ARVLSTYDIVITTYSLVAKEIPTNKQEAEIPGANLNVETLSIHYGSGAVSSRAARFPL
                     QGTSTPLLRIAWARIILDEAHNVKNPRVQTSIAVCKLQACARWAVTGTPIQNNLLDMY
                     SLLKFLRCSPFDEFNLWRSQVDNGSKKGGERLSILTKSLLLRRTKDQLDSTGRPLVIL
                     PQRKFQLHHLKLSEDEETVYNVFFARSRSALQSYLKRHESRGNQSGRSPNNPFSRVAL
                     EFGSEEPRHSEAADSPRSSTVHILSQLLRLRQCCCHLSLLKSALDPMELKGEGLVLSL
                     EEQLSALTLSELRDSEPSSTVSLNGTFFKMELFEGMRESTKISSLLAELEAIQRNSAS
                     QKSVIVSQWTNMLKVVALHLKKHGLTYATIDGSVNPKQRMDLVEAFNHSRGPQVMLIS
                     LLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACDRIYRVGQQKDVVIHRFVCEGTVEEK
                     ILQLQEKKKDLAKQVLSGSGESVTKLTLADLRVLFGI"
     polyA_site      4208
                     /gene="TTF2"
                     /gene_synonym="F2; HuF2; ZGRF6"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 gaacttgggg gacccagcga aatggaagaa gttaggtgtc cagagcacgg gactttctgc
       61 tttcttaaga ccggcgtccg cgatggcccg aataaaggaa agagcttcta cgtgtgccgg
      121 gcagacacgt gcagcttcgt gcgggccacc gacattcctg tttcccattg cttattgcat
      181 gaggactttg tggtagagct tcagggtttg cttctgccac aggacaagaa agaatacaga
      241 ttgttcttcc gatgcattag aagtaaggca gaggggaaac gctggtgtgg aagtattcca
      301 tggcaggatc ctgattccaa agaacattct gtatccaata agtctcagca tgcatctgag
      361 acatttcatc attcttccaa ctggctgaga aatccattca aggtacttga caagaatcaa
      421 gaaccagctc tctggaaaca gctcatcaaa ggtgaaggtg aggaaaagaa ggctgataag
      481 aagcaaagag aaaagggaga tcagcttttc gatcaaaaga aagaacagaa gcctgaaatg
      541 atggagaaag acctctcatc tggcctggta ccaaagaaaa aacaatctgt agttcaagag
      601 aagaagcaag aagagggagc agagattcag tgtgaggcag agactggagg cacacacaaa
      661 agagactttt ctgaaattaa atctcaacag tgccaaggta atgagcttac aagaccatct
      721 gcatcttctc aggagaaatc aagtggtaag agtcaagatg tccaaagaga atcagaacct
      781 ctgagagaaa aggttaccca gcttttgcct caaaatgttc acagtcacaa ctcaataagc
      841 aagccccaga aagggggacc cctcaacaag gagtacacga actgggaggc taaagaaaca
      901 aaggcaaagg atggccctag catacaggcc acccagaaaa gcctgcctca ggggcatttc
      961 caagagcggc cggagaccca cagtgtgcct gctcctggag gaccagcggc tcaggctgca
     1021 ccagcagcac cagggctttc cctgggtgag ggccgtgaag ctgccacaag cagtgacgac
     1081 gaggaggaag atgatgttgt ttttgtttcc tctaagcctg ggagccccct actctttgac
     1141 tcgactctgg acttagagac gaaggaaaac ctccaattcc ctgatcgaag tgtgcaaaga
     1201 aaggtgtctc ctgcctcagg tgtttccaag aaggtagaac cctcagaccc agtagcccgg
     1261 cgtgtctacc ttacaacaca actgaaacaa aagaagagca cactggcatc agtgaacatc
     1321 caggctcttc cagacaaggg tcagaagttg atcaaacaaa tccaggagct ggaggaagta
     1381 ctcagtggtc ttaccctttc cccagagcaa ggaactaatg agaagagtaa cagtcaagta
     1441 ccacagcaga gtcacttcac caaaactacc actggccctc cccacctggt gcctccccaa
     1501 ccccttcctc gtcgtggtac ccaacctgtg ggttctctag aactaaagtc tgcctgccag
     1561 gtgactgctg gaggatccag tcagtgctat cgaggccata caaaccaaga tcacgttcat
     1621 gcagtgtgga aaatcacaag tgaagccatc ggtcaactgc atcgctcact tgagtcatgt
     1681 cctggtgaga cggttgtggc agaagatccc gccgggctga aggtcccttt gctactacac
     1741 cagaagcagg cattggcttg gttactatgg cgagaaagtc agaagccaca aggaggaatt
     1801 ctggcagatg atatgggctt aggaaaaacc ctgacaatga ttgcgctcat cctgacccag
     1861 aagaatcaag agaaaaagga agaaaaggag aaaagcacag ctttgacgtg gctctccaaa
     1921 gatgactctt gtgactttac ttcccatgga acactaatca tctgtcctgc ctccctgatc
     1981 catcattgga aaaatgaggt ggagaaacgg gtgaacagca acaaactaag agtctatctc
     2041 taccatgggc caaaccggga ttcacgtgcc agagtcctct ctacatatga catcgtgatc
     2101 actacctata gcctcgtggc caaggagatt cccacaaaca agcaagaggc agagatccca
     2161 ggtgcaaacc tcaatgtgga gacgttgagt atccactatg ggtcaggtgc tgtttcgtca
     2221 agagcagcca gattcccact tcagggcacc tcaacacctt tgcttcgaat agcctgggct
     2281 cgaatcatat tggatgaagc tcacaatgtt aagaatcccc gagtgcagac ttccatagct
     2341 gtgtgtaagc tacaagcctg tgcccgttgg gctgtcactg gaacccccat tcaaaacaac
     2401 ttattggata tgtattcgct gctgaagttt ctccgttgct ctccatttga tgagttcaat
     2461 ctgtggagga gtcaggttga caatggctca aagaaaggag gagaacggtt aagtatttta
     2521 accaagagcc ttttgctgag gagaacaaaa gaccagctgg actctactgg cagacctttg
     2581 gtgatactgc cccagcgtaa atttcagttg caccatttaa agctttctga agatgaagag
     2641 actgtttaca atgtgttttt tgcaagatca aggtcagctc tgcaatccta tctaaaaaga
     2701 catgaaagta gaggcaacca atctggaaga agccctaata atccattcag tagagtggca
     2761 ctggagtttg ggtctgagga gcctagacac tcggaggcag cagactcacc gagatccagc
     2821 accgtccaca tactgtccca gttgctgaga ctccgccagt gttgctgtca tctttcttta
     2881 ctgaagtcgg ccctggatcc aatggaactg aagggtgaag gtcttgtcct ttccctggaa
     2941 gaacagctca gtgctttgac cttgtcagaa ctccgtgact cagagccatc ttccactgtt
     3001 tcccttaacg gcaccttctt caagatggag ctttttgaag gcatgcgaga gagcaccaag
     3061 atttcatctc tgttggcaga attggaggca attcaaagaa attcagcatc ccaaaagagt
     3121 gtcattgtct ctcagtggac caacatgctg aaagttgtag cattgcacct gaagaagcat
     3181 ggactgactt atgccaccat cgatggctct gtcaatccca agcagagaat ggacttggta
     3241 gaggcattta accactccag aggccctcag gtaatgctaa tctctctctt ggccggaggt
     3301 gttggtctaa acctgactgg aggaaatcac ctctttcttt tggacatgca ctggaatcca
     3361 tcacttgaag atcaagcttg tgaccgaatt taccgagtag ggcagcagaa agatgttgtc
     3421 atacacagat ttgtttgtga gggaacagta gaagaaaaga tcttacagct ccaagaaaaa
     3481 aagaaagatt tggccaaaca agttctatca gggtctggag aatctgtcac caagctcacc
     3541 ttggctgacc tcagagtcct ttttggcatc taacctcctg tggataaggg ctcagaatag
     3601 caccattgct gtgatgttgc acctgtaacc atctttttat gggtggagca gagagtcaat
     3661 ccctgcagcc accctgcagc cagccatctc tgcagttctc tcagtgcagg cagttcttcc
     3721 tctcaggctg aagatcaagg agatgctttg tacatgaaca gatgctgagt atctgttatc
     3781 attgtattgt ttagtgtcag tgtatcattt agtatttgta tcactgtacc atttagtgtt
     3841 gtatatcact cagtcattta atattggtta tcaccataca gtttaatatt tgtatcattt
     3901 ggttcattgt atcgtttagt atttctatta taacatttct atttgtagta tttgtataat
     3961 atttgtgtca tttttaatag tatttgtatt tttacaaatt tgcagtattt gtagcattta
     4021 gtatcattgt ttcatttagt atttggtaca atctaataaa tactaatcca gtccaatact
     4081 aatccaatcc aatactaata atactattgg tacaatccaa tactaataat actattggta
     4141 caatccaata ctaataatac taacagtagt attgatacaa tctaataaat aatgtgtttg
     4201 acagtgta
//
