LOCUS       NM_001105669            2958 bp    mRNA    linear   PRI 16-FEB-2024
DEFINITION  Homo sapiens tetratricopeptide repeat domain 24 (TTC24), mRNA.
ACCESSION   NM_001105669 XM_089384 XM_938033
VERSION     NM_001105669.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2958)
  AUTHORS   Venter,J.C., Adams,M.D., Myers,E.W., Li,P.W., Mural,R.J.,
            Sutton,G.G., Smith,H.O., Yandell,M., Evans,C.A., Holt,R.A.,
            Gocayne,J.D., Amanatides,P., Ballew,R.M., Huson,D.H., Wortman,J.R.,
            Zhang,Q., Kodira,C.D., Zheng,X.H., Chen,L., Skupski,M.,
            Subramanian,G., Thomas,P.D., Zhang,J., Gabor Miklos,G.L.,
            Nelson,C., Broder,S., Clark,A.G., Nadeau,J., McKusick,V.A.,
            Zinder,N., Levine,A.J., Roberts,R.J., Simon,M., Slayman,C.,
            Hunkapiller,M., Bolanos,R., Delcher,A., Dew,I., Fasulo,D.,
            Flanigan,M., Florea,L., Halpern,A., Hannenhalli,S., Kravitz,S.,
            Levy,S., Mobarry,C., Reinert,K., Remington,K., Abu-Threideh,J.,
            Beasley,E., Biddick,K., Bonazzi,V., Brandon,R., Cargill,M.,
            Chandramouliswaran,I., Charlab,R., Chaturvedi,K., Deng,Z., Di
            Francesco,V., Dunn,P., Eilbeck,K., Evangelista,C., Gabrielian,A.E.,
            Gan,W., Ge,W., Gong,F., Gu,Z., Guan,P., Heiman,T.J., Higgins,M.E.,
            Ji,R.R., Ke,Z., Ketchum,K.A., Lai,Z., Lei,Y., Li,Z., Li,J.,
            Liang,Y., Lin,X., Lu,F., Merkulov,G.V., Milshina,N., Moore,H.M.,
            Naik,A.K., Narayan,V.A., Neelam,B., Nusskern,D., Rusch,D.B.,
            Salzberg,S., Shao,W., Shue,B., Sun,J., Wang,Z., Wang,A., Wang,X.,
            Wang,J., Wei,M., Wides,R., Xiao,C., Yan,C., Yao,A., Ye,J., Zhan,M.,
            Zhang,W., Zhang,H., Zhao,Q., Zheng,L., Zhong,F., Zhong,W., Zhu,S.,
            Zhao,S., Gilbert,D., Baumhueter,S., Spier,G., Carter,C.,
            Cravchik,A., Woodage,T., Ali,F., An,H., Awe,A., Baldwin,D.,
            Baden,H., Barnstead,M., Barrow,I., Beeson,K., Busam,D., Carver,A.,
            Center,A., Cheng,M.L., Curry,L., Danaher,S., Davenport,L.,
            Desilets,R., Dietz,S., Dodson,K., Doup,L., Ferriera,S., Garg,N.,
            Gluecksmann,A., Hart,B., Haynes,J., Haynes,C., Heiner,C.,
            Hladun,S., Hostin,D., Houck,J., Howland,T., Ibegwam,C., Johnson,J.,
            Kalush,F., Kline,L., Koduru,S., Love,A., Mann,F., May,D.,
            McCawley,S., McIntosh,T., McMullen,I., Moy,M., Moy,L., Murphy,B.,
            Nelson,K., Pfannkoch,C., Pratts,E., Puri,V., Qureshi,H.,
            Reardon,M., Rodriguez,R., Rogers,Y.H., Romblad,D., Ruhfel,B.,
            Scott,R., Sitter,C., Smallwood,M., Stewart,E., Strong,R., Suh,E.,
            Thomas,R., Tint,N.N., Tse,S., Vech,C., Wang,G., Wetter,J.,
            Williams,S., Williams,M., Windsor,S., Winn-Deen,E., Wolfe,K.,
            Zaveri,J., Zaveri,K., Abril,J.F., Guigo,R., Campbell,M.J.,
            Sjolander,K.V., Karlak,B., Kejariwal,A., Mi,H., Lazareva,B.,
            Hatton,T., Narechania,A., Diemer,K., Muruganujan,A., Guo,N.,
            Sato,S., Bafna,V., Istrail,S., Lippert,R., Schwartz,R., Walenz,B.,
            Yooseph,S., Allen,D., Basu,A., Baxendale,J., Blick,L., Caminha,M.,
            Carnes-Stine,J., Caulk,P., Chiang,Y.H., Coyne,M., Dahlke,C.,
            Deslattes Mays,A., Dombroski,M., Donnelly,M., Ely,D., Esparham,S.,
            Fosler,C., Gire,H., Glanowski,S., Glasser,K., Glodek,A.,
            Gorokhov,M., Graham,K., Gropman,B., Harris,M., Heil,J.,
            Henderson,S., Hoover,J., Jennings,D., Jordan,C., Jordan,J.,
            Kasha,J., Kagan,L., Kraft,C., Levitsky,A., Lewis,M., Liu,X.,
            Lopez,J., Ma,D., Majoros,W., McDaniel,J., Murphy,S., Newman,M.,
            Nguyen,T., Nguyen,N., Nodell,M., Pan,S., Peck,J., Peterson,M.,
            Rowe,W., Sanders,R., Scott,J., Simpson,M., Smith,T., Sprague,A.,
            Stockwell,T., Turner,R., Venter,E., Wang,M., Wen,M., Wu,D., Wu,M.,
            Xia,A., Zandieh,A. and Zhu,X.
  TITLE     The sequence of the human genome
  JOURNAL   Science 291 (5507), 1304-1351 (2001)
   PUBMED   11181995
  REMARK    Erratum:[Science 2001 Jun 5;292(5523):1838]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL365181.24.
            
            On Jun 16, 2020 this sequence version replaced NM_001105669.3.
            
            ##Evidence-Data-START##
            CDS exon combination :: SRR14038192.1351843.1,
                                    SRR14038194.1566189.1 [ECO:0000331]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000368236.8/ ENSP00000357219.3
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-36                AL365181.24        90860-90895
            37-746              AL365181.24        92498-93207
            747-950             AL365181.24        93368-93571
            951-1079            AL365181.24        94179-94307
            1080-1192           AL365181.24        94475-94587
            1193-1291           AL365181.24        94934-95032
            1292-1389           AL365181.24        96014-96111
            1390-1496           AL365181.24        96262-96368
            1497-1610           AL365181.24        96850-96963
            1611-1707           AL365181.24        97086-97182
            1708-2958           AL365181.24        97606-98856
FEATURES             Location/Qualifiers
     source          1..2958
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q22"
     gene            1..2958
                     /gene="TTC24"
                     /note="tetratricopeptide repeat domain 24"
                     /db_xref="GeneID:164118"
                     /db_xref="HGNC:HGNC:32348"
     exon            1..36
                     /gene="TTC24"
                     /inference="alignment:Splign:2.1.0"
     exon            37..746
                     /gene="TTC24"
                     /inference="alignment:Splign:2.1.0"
     CDS             41..1789
                     /gene="TTC24"
                     /note="TPR repeat protein 24"
                     /codon_start=1
                     /product="tetratricopeptide repeat protein 24"
                     /protein_id="NP_001099139.2"
                     /db_xref="CCDS:CCDS53379.1"
                     /db_xref="GeneID:164118"
                     /db_xref="HGNC:HGNC:32348"
                     /translation="MSSPNPEDVPRRPEPEPSSSNKKKKKRKWLRQEASIQALTRAGH
                     GALQAGQNHEALNNFQRAFLLASKAPQTRDTPVLQACAFNLGAAYVETGDPARGLELL
                     LRAHPEEKAQGRRHGDQCFNVALAYHALGELPQALAWYHRALGHYQPQGDQGEAWAKM
                     GACYQALGQPELAAHCLQEASQAYAQERQLRAAALALGAAAGCMLKSGRHRVGEVVQV
                     LEKSRRLAERSTERRLLGHLYNDLGLGYSQLQLFPLAVEAFLQALPLCWVPGEQATVL
                     RNLGMAHNALGNYQEAREFHQKAADLHGSVGQRWEQGRSFGSLAFALSQLGDHKAARD
                     NYLHALQAARDSGDMKGQWQACEGLGAAAARLGQYDQALKYYKEALAQCQKEPDSVRE
                     RLVAKLADTVRTRLAQVGLVQTHTLTSAPGRLQAPGGASQAEGTPAKAGSSTAGVQHR
                     SSSGWEDEEFEEGHQKKKEERSANVPVRAGPGRPELCFLPGTVNHSHHLASSCPTFTK
                     HTPCRGTVLGKASIYSPGPRAHLPFVGPGPPRAEYPSILVPNGPQANRSSRWPRESLS
                     RSRQRRPMESGICTIV"
     exon            747..950
                     /gene="TTC24"
                     /inference="alignment:Splign:2.1.0"
     exon            951..1079
                     /gene="TTC24"
                     /inference="alignment:Splign:2.1.0"
     exon            1080..1192
                     /gene="TTC24"
                     /inference="alignment:Splign:2.1.0"
     exon            1193..1291
                     /gene="TTC24"
                     /inference="alignment:Splign:2.1.0"
     exon            1292..1389
                     /gene="TTC24"
                     /inference="alignment:Splign:2.1.0"
     exon            1390..1496
                     /gene="TTC24"
                     /inference="alignment:Splign:2.1.0"
     exon            1497..1610
                     /gene="TTC24"
                     /inference="alignment:Splign:2.1.0"
     exon            1611..1707
                     /gene="TTC24"
                     /inference="alignment:Splign:2.1.0"
     exon            1708..2958
                     /gene="TTC24"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2939..2944
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TTC24"
                     /note="hexamer: AATAAA"
     polyA_site      2958
                     /gene="TTC24"
                     /note="major polyA site"
ORIGIN      
        1 attccagaga gccagctgcg gagaagaccc aaggagccct atgtcttccc ccaaccctga
       61 ggatgtgccc cggaggccag aacctgagcc ctcaagctcc aataagaaaa agaagaaaag
      121 aaagtggctg cggcaagaag ccagcatcca agccctcacc agggctggcc atggggccct
      181 tcaggctggc cagaaccatg aagccttgaa caacttccag agggccttcc ttctggcctc
      241 caaggcccca caaaccaggg atacccctgt gctccaggcc tgcgccttca acctgggggc
      301 tgcctatgtg gagactgggg acccagccag aggccttgag ctactcctgc gagcccaccc
      361 tgaagagaag gcacagggca ggcgacacgg cgaccaatgt ttcaatgtgg ctttggccta
      421 ccatgccctc ggcgagctgc ctcaagcttt ggcctggtac cacagggccc tgggccacta
      481 ccagccacag ggtgaccagg gagaagcctg ggcaaaaatg ggagcctgct accaggctct
      541 gggacagcct gagctagcag cccactgcct gcaggaagca agccaggcct atgctcaaga
      601 gagacagctg cgggccgcag ccctggcact gggggctgcg gcaggatgta tgctgaagag
      661 tgggcggcat cgggtggggg aagttgtgca ggtgctggag aaaagccgga ggcttgccga
      721 gaggagcact gagaggcgac tgctggggca cctctataac gatctaggcc tgggctactc
      781 ccagctccag ctgttcccgc tggccgtgga ggccttcctg caggccctgc ccctgtgctg
      841 ggtgccagga gagcaggcca cagtgctaag aaacctcggg atggcccaca atgccctcgg
      901 caactatcag gaagctcggg agtttcacca gaaggctgct gacctacacg gctctgtggg
      961 gcagcggtgg gagcagggcc ggagctttgg cagcctggcc tttgcattga gccagctggg
     1021 ggaccacaag gctgccagag acaactacct gcatgccctg caggctgccc gggactctgg
     1081 ggacatgaag ggacagtggc aggcctgtga gggtctgggg gctgctgcag ccaggctggg
     1141 gcagtatgac caggccttga agtactataa ggaagcactg gcccagtgtc agaaggagcc
     1201 agattctgtg cgagaacggc tggtggccaa gctggcagac accgtgagga cgcgcttggc
     1261 ccaggtgggg ctggtccaga ctcacaccct gacttcggct ccgggaagac tccaggctcc
     1321 aggtggggcc agccaggcgg aggggacccc agcaaaggca ggaagcagca cagcaggtgt
     1381 ccagcacaga tcttccagtg ggtgggaaga tgaagagttt gaggagggcc accagaagaa
     1441 aaaagaggag aggtcggcaa acgttccggt gagggctggg ccgggaagac cagagctgtg
     1501 tttccttcca ggcacagtga atcattcgca ccatctagct tctagttgcc ccacgtttac
     1561 caagcacacg ccctgcagag ggacagtcct cggcaaagcc tccatctata gtccaggacc
     1621 cagggcccat cttccatttg taggtccagg ccctcccaga gcggagtacc ctagcatctt
     1681 ggtacccaat ggccctcaag ccaataggtc atccaggtgg cccagggaaa gcctcagcag
     1741 gagccgccag aggagaccca tggagtcggg catctgcact attgtgtgac ctccccctgc
     1801 cagcctcagc cctcatccct gaagcacctg tccaacacgc acacactagg gggtcctggg
     1861 gaccaagcct cttcccagtt gctcagccct gcagggatgt ggaacacagt gcagccagtg
     1921 gactcctgag gaggctggcc aagggctttg caggctcggc cctgagaggt tctgtttgtt
     1981 cctccttggg atttttggac tcagtaggta aaagaaaaaa ggaaaatgga tggcaaattc
     2041 cctgtctttc tgaatccaaa tcttacgatt gctaggggcc tggcagttct aaaaactgac
     2101 ttcgtggtca agtagctttg gagtcactga ctgtctccag acgtccattt ttgcacatga
     2161 gaaatgagga tataatacta cagaagaggc atcttaccca accaatgcac cttacttctc
     2221 tgtgaaacac aggggatgct gggcgcaggc ctaggctgtg gcctgtagcc tgtaggacag
     2281 ctcctgccag cagccacagg aacagtgatg tgatgtaaca tttcccaagt acttagctca
     2341 tgccccaccc tattctaggt gcttagctca ggccccaccc tattctaggt gcttagctca
     2401 ggccccaccc tattctaggt gcttagctca tgccccaccc tattctaggt gcttagctca
     2461 tgccccaccc tattctaggt gcttcacaag tgtattctcc tctaatcctc acaacaaata
     2521 tatgaggtgc tattatcccc tttcgcaaat gaggaaaata aggcacaaag cttcagtaat
     2581 ctgaattccc aggtcacata actagtatgt agagaagctg ggaatcaaac ccaggcagtg
     2641 agcactttct agaatgctgt gcagttccac ttccccagct aagcccttgc ttacccagag
     2701 tccattgtga tttaatatca agtgtgtcta tgcccgttgt atgtgttatt gtaattcata
     2761 atgtaattaa atactataca cattgatgaa caggccaggt gagatggctc acccttgtaa
     2821 tcctagcact ttgcgaggcc aaggtgggag gattgcttga gcccaggagt ttgagaccac
     2881 cctgggcaac atagtgagac cccatgtcaa tgtaaaagaa aatttatctt taaaaaaaaa
     2941 taaattgatg aactgaga
//
