LOCUS       NM_001003937            3052 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens TSPY like 6 (TSPYL6), mRNA.
ACCESSION   NM_001003937 XM_371494
VERSION     NM_001003937.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3052)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 3052)
  AUTHORS   Liang,Y., Zhang,R., Zhang,S., Ji,G., Shi,P., Yang,T., Liu,F.,
            Feng,J., Li,C., Guo,D. and Chen,M.
  TITLE     Association of ACYP2 and TSPYL6 Genetic Polymorphisms with Risk of
            Ischemic Stroke in Han Chinese Population
  JOURNAL   Mol Neurobiol 54 (8), 5988-5995 (2017)
   PUBMED   27686078
  REMARK    GeneRIF: genetic polymorphisms of ACYP2 and TSPYL6 are associated
            with increased risk of developing ischemic stroke
REFERENCE   3  (bases 1 to 3052)
  AUTHORS   Liu,M., Li,B., Guo,W., Zhang,X., Chen,Z., Li,J., Yan,M., Chen,C.
            and Jin,T.
  TITLE     Association between single nucleotide polymorphisms in the TSPYL6
            gene and breast cancer susceptibility in the Han Chinese population
  JOURNAL   Oncotarget 7 (34), 54771-54781 (2016)
   PUBMED   27458158
  REMARK    GeneRIF: Findings indicate a significant association between single
            nucleotide polymorphisms (SNPs) in the testis-specific
            Y-encoded-like protein 6 (TSPYL6) gene and breast cancer (BC) risk
            in a Han Chinese population.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DB073493.1, AK097417.1 and BC068576.1.
            
            On Nov 23, 2018 this sequence version replaced NM_001003937.2.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AK097417.1, BC068576.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000317802.9/ ENSP00000417919.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3                 DB073493.1         44-46
            4-1546              AK097417.1         1-1543
            1547-1547           BC068576.1         1525-1525
            1548-3052           AK097417.1         1545-3049
FEATURES             Location/Qualifiers
     source          1..3052
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2p16.2"
     gene            1..3052
                     /gene="TSPYL6"
                     /note="TSPY like 6"
                     /db_xref="GeneID:388951"
                     /db_xref="HGNC:HGNC:14521"
     exon            1..3052
                     /gene="TSPYL6"
                     /inference="alignment:Splign:2.1.0"
     CDS             79..1311
                     /gene="TSPYL6"
                     /note="TSPY-like protein 6; testicular tissue protein Li
                     211"
                     /codon_start=1
                     /product="testis-specific Y-encoded-like protein 6"
                     /protein_id="NP_001003937.2"
                     /db_xref="CCDS:CCDS42682.1"
                     /db_xref="GeneID:388951"
                     /db_xref="HGNC:HGNC:14521"
                     /translation="MSLPESPHSPATLDYALEDPHQGQRSREKSKATEVMADMFDGRL
                     EPIVFPPPRLPEEGVAPQDPADGGHTFHILVDAGRSHGAIKAGQEVTPPPAEGLEAAS
                     ASLTTDGSLKNGFPGEETHGLGGEKALETCGAGRSESEVIAEGKAEDVKPEECAMFSA
                     PVDEKPGGEEMDVAEENRAIDEVNREAGPGPGPGPLNVGLHLNPLESIQLELDSVNAE
                     ADRALLQVERRFGQIHEYYLEQRNDIIRNIPGFWVTAFRHHPQLSAMIRGQDAEMLSY
                     LTNLEVKELRHPRTGCKFKFFFQRNPYFRNKLIVKVYEVRSFGQVVSFSTLIMWRRGH
                     GPQSFIHRNRHVICSFFTWFSDHSLPESDRIAQIIKEDLWSNPLQYYLLGEDAHRARR
                     RLVREPVEIPRPFGFQCG"
     regulatory      3029..3034
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TSPYL6"
                     /note="hexamer: AATAAA"
     polyA_site      3052
                     /gene="TSPYL6"
                     /note="major polyA site"
ORIGIN      
        1 gccattttgt gtgaggaacg ttgacgctac ctacctctgg cctggcctct acccactgct
       61 gccctggccg ctaccaacat gagcctcccg gagagtcctc acagccccgc tactctcgac
      121 tatgctctgg aagacccgca ccagggccag aggtcccgag aaaagagcaa ggcgacagag
      181 gtaatggcag atatgtttga tggccgcttg gagccaatcg tgttcccacc gccccggctt
      241 ccagaggagg gggtcgcgcc ccaggatccc gcagatggtg gccatacttt ccacatcttg
      301 gtcgatgcgg gtcgcagtca tggagccatc aaagcggggc aggaagtgac tccaccaccc
      361 gcggagggcc tagaagcggc ctctgcctcg ctgacaactg acggcagcct caaaaatggc
      421 tttccgggtg aagagacgca cggcctaggt ggggagaagg ctctagaaac ctgtggggca
      481 gggaggtcgg agtctgaagt gattgcagag gggaaggccg aggacgtgaa gcctgaggag
      541 tgtgccatgt tctcagcccc agtggatgag aagccaggag gcgaagaaat ggacgtggcg
      601 gaagaaaaca gagcaataga tgaggtaaac agggaggcag ggcctgggcc cgggcccggg
      661 cccctgaacg tgggtctcca cctgaacccc ctggagtcca tccagctgga actggactcc
      721 gtgaatgcag aggctgacag ggcgctcctg caggtggagc gcaggtttgg gcagattcat
      781 gaatactacc tggagcagag gaatgacatc attcgcaata tcccgggctt ctgggtcact
      841 gctttccgcc accacccaca gctgtctgcc atgattagag gccaagatgc cgagatgtta
      901 agctacttaa ccaatttgga agtgaaggag ctcagacacc ctaggacagg ctgcaagttt
      961 aagttcttct ttcaaagaaa cccttacttc agaaacaagc tgattgtaaa ggtgtatgag
     1021 gtcagatcct tcggccaagt ggtgtctttt tccactctaa tcatgtggcg ccggggccat
     1081 ggaccccagt ccttcattca taggaaccga catgtcatct gcagcttctt cacctggttt
     1141 tcagaccaca gccttccaga gtccgacagg attgctcaga ttattaaaga ggacctctgg
     1201 tcaaatccac tgcagtacta cctgttgggt gaagacgccc atagagctag acgtcgcctg
     1261 gtaagggagc cagtggagat ccccaggccc tttgggttcc agtgtggtta acctttgcct
     1321 ttggaattac tcctgcagaa ggttgcctgc caccaccagc tggacctgag cttgggcaac
     1381 agcattaggt atgcccttta ctttttttgt tctgactttc ctgtaccctc tgtttaaact
     1441 ttccgttctc tcaacctgaa gattgagacc ttggtggctg tgctgctccc ctttcacctg
     1501 gtcgtcttgc tattctgcat taacatcaca tgctcccagc cgatgggtca catccttcta
     1561 agcgaagcga atgatgctgt aggttacact gtatttacct ttgtttggac tcggtttgtt
     1621 cccaggacct ctggtctggc tcctcctact tggatttcta gctgtgtcta agaacctatt
     1681 cagctcaccc tgctctgcat ctgacagtac aggtgcatgg cctgtggaca attgctgggc
     1741 attaatgaag tcaagggaga acagcagggg gcaagttggt ctgtgtgaat tatgggaccc
     1801 cattactttt cctgagactg gtcacctatt gctgcctgct actggctatt cccaagtact
     1861 gctacttggg cagctccctg ctgagtgaac atatcccaga ccattgccag ctccactctc
     1921 tggtttctaa taaacaggga tctccagaac actggtggtg gacacagctt tcctgtcagc
     1981 acacaaaaga cctgttcctc ttccaaaaga cctctcttta ccaccaccac cctcatcact
     2041 cagaaaccct actgtttgtt agacaggtgg ttgaggggac atgtcagacc ctatcctcat
     2101 ggcaaggtta atatgttggt gttcttgaca agtaccaggc tttctcagcc acaaccagtg
     2161 gattcattca aaatctaggt acctttattt gcctcccttc ctgaacctaa tgaagtgcca
     2221 gagtgagtgt acactttctt ttctctcatc tctcataaat ctcttctgtc ttcctttaaa
     2281 aaaaacaaaa gtagtagttc agaaacatcc gcagaagcag gctttttagt ttcttggctc
     2341 tctttgtcat gtccagaggc aggctgttct gtaaaataga ctgccagacc tcttattgcc
     2401 cattctcctt tcttctcagc ccctcacccc tctttagcaa ttcctagagg gtttaaagga
     2461 ctacagagct gtatggaatg aaaggtgatt tctagttcag agtggataga agaactaaag
     2521 agattgtgat gggtgctcta ggcagggaaa actgaacaaa aaggcagaaa tgattcaggg
     2581 gaaaatcggg cctagaattt acactgggtt gactagttat gatgggaaga gaagtacttt
     2641 tttttagtat gcacgtagaa gaatagaaga tggttggagt gttaaatatg ttccctagag
     2701 aagggttctt tgaagaaaca ctgcaatttt gggtgttctc tttcttgttt gcatatggcc
     2761 ttacttatgt ggaagattaa tactgtgtta taatattttc tctttctgtt tactgggaag
     2821 attcagctgt acagattttc ttttactttc aaatagaaat atttggaata atatcagtct
     2881 ttcttttttg tacattatgt ggatatggat attcatggca gttttcagcc tgttcttgtt
     2941 tctgttaaaa ccgtatcttt aacattttaa tttgaataac ttggtcttat ctgatgcgga
     3001 agactggaaa ctattgtgtt catgggtaaa taaactacaa aatatttatg gc
//
