LOCUS       NM_021648               4112 bp    mRNA    linear   PRI 20-SEP-2024
DEFINITION  Homo sapiens TSPY like 4 (TSPYL4), mRNA.
ACCESSION   NM_021648
VERSION     NM_021648.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4112)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   2  (bases 1 to 4112)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   3  (bases 1 to 4112)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Paulo,J.A., Cannon,J.R., Ting,L.,
            Baltier,K., Colby,G., Gebreab,F., Gygi,M.P., Parzen,H., Szpyt,J.,
            Tam,S., Zarraga,G., Pontano-Vaites,L., Swarup,S., White,A.E.,
            Schweppe,D.K., Rad,R., Erickson,B.K., Obar,R.A., Guruharsha,K.G.,
            Li,K., Artavanis-Tsakonas,S., Gygi,S.P. and Harper,J.W.
  TITLE     Architecture of the human interactome defines protein communities
            and disease networks
  JOURNAL   Nature 545 (7655), 505-509 (2017)
   PUBMED   28514442
REFERENCE   4  (bases 1 to 4112)
  AUTHORS   Mungall,A.J., Palmer,S.A., Sims,S.K., Edwards,C.A., Ashurst,J.L.,
            Wilming,L., Jones,M.C., Horton,R., Hunt,S.E., Scott,C.E.,
            Gilbert,J.G., Clamp,M.E., Bethel,G., Milne,S., Ainscough,R.,
            Almeida,J.P., Ambrose,K.D., Andrews,T.D., Ashwell,R.I.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Barker,D.J.,
            Barlow,K.F., Bates,K., Beare,D.M., Beasley,H., Beasley,O.,
            Bird,C.P., Blakey,S., Bray-Allen,S., Brook,J., Brown,A.J.,
            Brown,J.Y., Burford,D.C., Burrill,W., Burton,J., Carder,C.,
            Carter,N.P., Chapman,J.C., Clark,S.Y., Clark,G., Clee,C.M.,
            Clegg,S., Cobley,V., Collier,R.E., Collins,J.E., Colman,L.K.,
            Corby,N.R., Coville,G.J., Culley,K.M., Dhami,P., Davies,J.,
            Dunn,M., Earthrowl,M.E., Ellington,A.E., Evans,K.A., Faulkner,L.,
            Francis,M.D., Frankish,A., Frankland,J., French,L., Garner,P.,
            Garnett,J., Ghori,M.J., Gilby,L.M., Gillson,C.J., Glithero,R.J.,
            Grafham,D.V., Grant,M., Gribble,S., Griffiths,C., Griffiths,M.,
            Hall,R., Halls,K.S., Hammond,S., Harley,J.L., Hart,E.A.,
            Heath,P.D., Heathcott,R., Holmes,S.J., Howden,P.J., Howe,K.L.,
            Howell,G.R., Huckle,E., Humphray,S.J., Humphries,M.D., Hunt,A.R.,
            Johnson,C.M., Joy,A.A., Kay,M., Keenan,S.J., Kimberley,A.M.,
            King,A., Laird,G.K., Langford,C., Lawlor,S., Leongamornlert,D.A.,
            Leversha,M., Lloyd,C.R., Lloyd,D.M., Loveland,J.E., Lovell,J.,
            Martin,S., Mashreghi-Mohammadi,M., Maslen,G.L., Matthews,L.,
            McCann,O.T., McLaren,S.J., McLay,K., McMurray,A., Moore,M.J.,
            Mullikin,J.C., Niblett,D., Nickerson,T., Novik,K.L., Oliver,K.,
            Overton-Larty,E.K., Parker,A., Patel,R., Pearce,A.V., Peck,A.I.,
            Phillimore,B., Phillips,S., Plumb,R.W., Porter,K.M., Ramsey,Y.,
            Ranby,S.A., Rice,C.M., Ross,M.T., Searle,S.M., Sehra,H.K.,
            Sheridan,E., Skuce,C.D., Smith,S., Smith,M., Spraggon,L.,
            Squares,S.L., Steward,C.A., Sycamore,N., Tamlyn-Hall,G., Tester,J.,
            Theaker,A.J., Thomas,D.W., Thorpe,A., Tracey,A., Tromans,A.,
            Tubby,B., Wall,M., Wallis,J.M., West,A.P., White,S.S.,
            Whitehead,S.L., Whittaker,H., Wild,A., Willey,D.J., Wilmer,T.E.,
            Wood,J.M., Wray,P.W., Wyatt,J.C., Young,L., Younger,R.M.,
            Bentley,D.R., Coulson,A., Durbin,R., Hubbard,T., Sulston,J.E.,
            Dunham,I., Rogers,J. and Beck,S.
  TITLE     The DNA sequence and analysis of human chromosome 6
  JOURNAL   Nature 425 (6960), 805-811 (2003)
   PUBMED   14574404
REFERENCE   5  (bases 1 to 4112)
  AUTHORS   Nakayama,M., Kikuno,R. and Ohara,O.
  TITLE     Protein-protein interactions between large proteins: two-hybrid
            screening using a functionally classified library composed of long
            cDNAs
  JOURNAL   Genome Res 12 (11), 1773-1784 (2002)
   PUBMED   12421765
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL134793.1, AB018264.1 and BC040453.1.
            
            On May 17, 2019 this sequence version replaced NM_021648.4.
            
            ##Evidence-Data-START##
            Transcript is intronless :: SRR7346977.1459047.1,
                                        SRR1803612.213752.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000420283.3/ ENSP00000410943.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-8                 AL134793.1         24-31
            9-4106              AB018264.1         1-4098
            4107-4112           BC040453.1         4074-4079
FEATURES             Location/Qualifiers
     source          1..4112
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6q22.1"
     gene            1..4112
                     /gene="TSPYL4"
                     /gene_synonym="dJ486I3.2"
                     /note="TSPY like 4"
                     /db_xref="GeneID:23270"
                     /db_xref="HGNC:HGNC:21559"
                     /db_xref="MIM:619586"
     exon            1..4112
                     /gene="TSPYL4"
                     /gene_synonym="dJ486I3.2"
                     /inference="alignment:Splign:2.1.0"
     CDS             68..1312
                     /gene="TSPYL4"
                     /gene_synonym="dJ486I3.2"
                     /note="TSPY-like protein 4"
                     /codon_start=1
                     /product="testis-specific Y-encoded-like protein 4"
                     /protein_id="NP_067680.3"
                     /db_xref="CCDS:CCDS5106.1"
                     /db_xref="GeneID:23270"
                     /db_xref="HGNC:HGNC:21559"
                     /db_xref="MIM:619586"
                     /translation="MSGLDGGNKLPLAQTGGLAAPDHASGDPDRDQCQGLREETEATQ
                     VMANTGGGSLETVAEGGASQDPVDCGPALRVPVAGSRGGAATKAGQEDAPPSTKGLEA
                     ASAAEAADSSQKNGCQLGEPRGPAGQKALEACGAGGLGSQMIPGKKAKEVTTKKRAIS
                     AAVEKEGEAGAAMEEKKVVQKEKKVAGGVKEETRPRAPKINNCMDSLEAIDQELSNVN
                     AQADRAFLQLERKFGRMRRLHMQRRSFIIQNIPGFWVTAFRNHPQLSPMISGQDEDML
                     RYMINLEVEELKHPRAGCKFKFIFQGNPYFRNEGLVKEYERRSSGRVVSLSTPIRWHR
                     GQDPQAHIHRNREGNTIPSFFNWFSDHSLLEFDRIAEIIKGELWPNPLQYYLMGEGPR
                     RGIRGPPRQPVESARSFRFQSG"
     regulatory      4093..4098
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TSPYL4"
                     /gene_synonym="dJ486I3.2"
                     /note="hexamer: AATAAA"
     polyA_site      4112
                     /gene="TSPYL4"
                     /gene_synonym="dJ486I3.2"
                     /note="major polyA site"
ORIGIN      
        1 gggcagagct cggccgctgc ggaggacaag gaactctccc tctcccacta gtctgacttc
       61 ttccaaaatg agcggcctgg atgggggcaa caagctccct ctcgcccaaa ccggcggcct
      121 ggctgctccc gaccatgcct caggagatcc ggaccgagac cagtgccaag ggctccgtga
      181 agaaaccgag gcgacacagg tgatggcgaa cacaggtggg ggcagcctgg agaccgttgc
      241 ggaggggggt gcatcccagg atcctgtcga ctgtggcccc gcgctccgcg tcccagttgc
      301 cgggagtcgc ggcggtgcag cgaccaaagc cgggcaggag gatgctccac cttctacgaa
      361 aggtctggaa gcagcctctg ccgccgaggc tgctgacagc agccagaaaa atggctgtca
      421 gcttggagag ccccgtggcc ctgctgggca gaaggctcta gaagcctgtg gcgcaggggg
      481 cttggggtct cagatgatac cggggaagaa ggccaaggaa gtgacgacta aaaaacgcgc
      541 catctcggca gcagtggaaa aggagggaga agcaggggcg gcgatggagg aaaagaaggt
      601 agtgcagaag gaaaaaaagg tggcaggagg ggtgaaagag gagacacggc ccagggcccc
      661 gaagatcaat aactgcatgg actcactgga ggccatcgat caagagttgt caaacgtaaa
      721 tgcccaggct gacagggcct tccttcagct tgagcgcaag tttggccgca tgcgaaggct
      781 ccacatgcag cgcagaagtt tcattatcca gaatatccca ggtttctggg ttactgcctt
      841 tcgaaaccac ccccagctgt cacctatgat cagtggccaa gatgaagaca tgctgaggta
      901 catgatcaat ttggaggtgg aggagcttaa acaccccaga gcaggctgca aattcaagtt
      961 catctttcag ggcaacccct acttccgaaa tgaggggctt gtcaaggaat atgaacgcag
     1021 atcctctggc cgggtggtgt ctctttccac tccaatccgc tggcaccgag gccaagaccc
     1081 ccaggctcat atccacagaa accgggaagg gaacactatc cctagtttct tcaactggtt
     1141 ttcagaccac agccttctag aattcgacag aattgcagag attatcaaag gagaactgtg
     1201 gcccaatccc ctacaatact acctgatggg tgaagggccc cgtagaggaa ttcgaggccc
     1261 accaaggcag ccagtggaga gcgccagatc cttcaggttc cagtctggct aatctctgtc
     1321 ctgtgagaag cttctgcaca agtttcctta ccacctcctc ttggacctat gcttggccaa
     1381 cagcatgcag tcttccatct gctttctctt catactgtgg attatctttt cctttggttc
     1441 taaatcttca gtaatcggtt gcaagattgt tggcttacct gcctgtgcca ttcttcctct
     1501 gggccttcat gcttttctgc attgtgttaa catgtttcaa gtgcatggcc ttctacggct
     1561 tctatgccaa gcgtatgata ctatagatat agtgtaccat actgcctttc tttgcatggc
     1621 ttggacccta tctgtgacca tgctcttctc ccaatttaag tggttctgta ccacaaagaa
     1681 tcttgataca ttttcacaaa taactgattg ggcttcatac tttatgctgg ctgtgtcctg
     1741 atacccatgt acttatggta agctatttgg gtattaccac tgcaagacaa aactgatatc
     1801 ttaacccggc catcaaccca aattggacat tccagactac caccaactgg atcccagctg
     1861 ccttcctggg cttgtgccat ccaccctact ggttatctga tagaacaagc tggtggctga
     1921 tgggtgactg ctaggcgtga ctgaggtaat agatgaaaag tgttctatgt tatcacattg
     1981 gttttcctgt acctttggtt actctacgtc atgaccagct gctggtgagt atgaagcctg
     2041 tgctatagcc cacccctact cactctcacc ttctggttga actttgctta ggccaccatt
     2101 gtctgcctca tcaggaacta tctgtagacg tagctcccag ggagctcaca gcaacacccc
     2161 ctaccaccag gatgggcagt aatatgtgac agagcccaaa gcaaggctgg aacgcagtcc
     2221 cttccagctt agtctttctg actcctagcc aacaaaccat ccttaatgtg agcaacttct
     2281 ttaggcattt cctcttttcc ccgcctgcac ccactctgaa catgacaaaa gttgccagag
     2341 ttggggcatt gaggaagaga tatttctgga atgtgagact tgttatgcct ctgtctcttt
     2401 ctctccctcc tcctcccctc tccctccccc tctccctccc atcccttttc ttccctttca
     2461 ctctgaagca gttttagctt attaacagaa aacaaaactg gcaaagcagg ctttttgttt
     2521 aatttgctct ttccctgatt gtgttcagag agaaaggtta tgattaaatg ggctccagat
     2581 ctcttattgc ccttattcct ccaccccact tcttttagca aggtctgaaa gtttcaaagg
     2641 gagacctata ggttaattgt ttagttatag gcagtgttaa attaggcaga ttttgacata
     2701 tttatctttt taccccatcc attctaccaa aacctgtgta tttcttgagt ttttagtttg
     2761 agaagctgga aagagagaga agggcctcac agtgatgggt tcaggacggg tcaaaggcaa
     2821 aggcctttgt gatgtgagca aaggcaacca aaacttagcc tcactccact tttctaaaga
     2881 tggaaattct tttttgggcc ttggactgct tctagggtag cattttgtag gtcactcttc
     2941 tcctttgtac tattttgttt ctgccctgat gtcccttggg tctccatcct actgcctggc
     3001 tttcttggcc ctcatttctc agcttctgca tttccttccc tgctcctaac aaatgaagaa
     3061 gcaggctgca gcctgcattg tggaagatct ccagcctcct tgtaggggat aaggggatgt
     3121 gcagcatctg tgtggatttt cacggacaag ttccagtagg tgggacagtg atgccgtcaa
     3181 ggcttagtta tgatcatgtg tggtgataaa gaccatccac catcaccctt ttcccctttg
     3241 gttttgaagg ccttgcccta agctacctga gggtttagga ggtctgaaca cacacagtgg
     3301 agaggttaat ctaggttggg aaactgagta aaagtccaga gcaggaatga gcctgctgtg
     3361 gcgtgggttt ggaaaggctc acaggaaaga acctgcagga tcaggggtgg gaggggaggc
     3421 ccctgaggtg ctctccaggg aagaggggct ggggtttaaa tagcatgctt ggaggaagat
     3481 tttccttcaa tttttcctaa gtccttgaat tcaccagtag atttttgtaa acaaaatgta
     3541 agtcgatgtt ttctctcaat tatcctagga gtgaccttta tatgtgtgga agattaatgg
     3601 tatatgctcc ttatgtcact gtttttgagt aaaatccatt tcctttctct gtttcagcct
     3661 atgacaaaat tgatgtttac aggcctgctt tttgcttata attgacaaca tgtgcaaaaa
     3721 taccaaattt gtgtcctgtg cagtatgaag aattcagtga atattcatta atgtattagc
     3781 ttgttttgct ctctgttcat atatggctct attcttagaa atataatttg aatgtgatct
     3841 ttcaatagtc tgaatatttt acaaattata gctatgtctt gtgaaaataa cctcaaaaag
     3901 aaaaatacga ctctgttgtc ttacttgata tttcttgccc tagtaatgta cttgacattt
     3961 atgttcctaa gcagtgtaag taccagtaga atttctctgt caaactcaat gatcatttag
     4021 tacttttgtc ttctcccatg tgcttgaagg aaaaataaag tgtcactacc gtatttcttg
     4081 ttttcatcaa aaaataaaaa taatttaaaa aa
//
