LOCUS       NM_001396063            1179 bp    mRNA    linear   PRI 08-APR-2024
DEFINITION  Homo sapiens testis specific protein Y-linked 9 (TSPY9), mRNA.
ACCESSION   NM_001396063
VERSION     NM_001396063.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1179)
  AUTHORS   Lau,Y.C., Li,Y. and Kido,T.
  TITLE     Battle of the sexes: contrasting roles of testis-specific protein
            Y-encoded (TSPY) and TSPX in human oncogenesis
  JOURNAL   Asian J Androl 21 (3), 260-269 (2019)
   PUBMED   29974883
  REMARK    Review article
REFERENCE   2  (bases 1 to 1179)
  AUTHORS   Xue,Y. and Tyler-Smith,C.
  TITLE     An Exceptional Gene: Evolution of the TSPY Gene Family in Humans
            and Other Great Apes
  JOURNAL   Genes (Basel) 2 (1), 36-47 (2011)
   PUBMED   24710137
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1179)
  AUTHORS   Delbridge,M.L., Longepied,G., Depetris,D., Mattei,M.G.,
            Disteche,C.M., Marshall Graves,J.A. and Mitchell,M.J.
  TITLE     TSPY, the candidate gonadoblastoma gene on the human Y chromosome,
            has a widely expressed homologue on the X - implications for Y
            chromosome evolution
  JOURNAL   Chromosome Res 12 (4), 345-356 (2004)
   PUBMED   15241014
REFERENCE   4  (bases 1 to 1179)
  AUTHORS   Vogel,T. and Schmidtke,J.
  TITLE     Structure and function of TSPY, the Y-chromosome gene coding for
            the 'testis-specific protein'
  JOURNAL   Cytogenet Cell Genet 80 (1-4), 209-213 (1998)
   PUBMED   9678360
  REMARK    Review article
REFERENCE   5  (bases 1 to 1179)
  AUTHORS   Manz,E., Schnieders,F., Brechlin,A.M. and Schmidtke,J.
  TITLE     TSPY-related sequences represent a microheterogeneous gene family
            organized as constitutive elements in DYZ5 tandem repeat units on
            the human Y chromosome
  JOURNAL   Genomics 17 (3), 726-731 (1993)
   PUBMED   8244388
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC006156.5.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA1968968,
                              SAMEA2148093 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000440215.5/ ENSP00000499192.1
            RefSeq Select criteria :: based on manual assertion, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-550               AC006156.5         33554-34103
            551-628             AC006156.5         34711-34788
            629-740             AC006156.5         34917-35028
            741-886             AC006156.5         35130-35275
            887-968             AC006156.5         35382-35463
            969-1179            AC006156.5         36158-36368
FEATURES             Location/Qualifiers
     source          1..1179
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="Y"
                     /map="Yp11.2"
     gene            1..1179
                     /gene="TSPY9"
                     /gene_synonym="TSPY9P"
                     /note="testis specific protein Y-linked 9"
                     /db_xref="GeneID:728132"
                     /db_xref="HGNC:HGNC:37472"
     exon            1..550
                     /gene="TSPY9"
                     /gene_synonym="TSPY9P"
                     /inference="alignment:Splign:2.1.0"
     CDS             47..991
                     /gene="TSPY9"
                     /gene_synonym="TSPY9P"
                     /note="testis specific protein Y-linked 9, pseudogene"
                     /codon_start=1
                     /product="testis-specific Y-encoded protein 9"
                     /protein_id="NP_001382992.1"
                     /db_xref="CCDS:CCDS94712.1"
                     /db_xref="GeneID:728132"
                     /db_xref="HGNC:HGNC:37472"
                     /translation="MRPEGSLTYRVPERLRQGFCGVGRAAQALVCASAKEGTAFRMEA
                     VQEGAAGVESEQAALGEEAVLLLDDIMAEVEVVAEVEVVAEEEGLVERREEAQRAQQA
                     VPGPGPMTPESALEELLAVQVELEPVNAQARKAFSRQREKMERRRKPQLDRRGAVIQS
                     VPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVEEEKHPVHLCKIMLFFRSNPYFQ
                     NKVITKEYLVNITEYRASHSTPIEWYPDYEVEAYRRRHHNSSLNFFNWFSDHNFAGSN
                     KIAEILCKDLWRNPLQYYKRMKPPEEGTETSGDSQLLS"
     exon            551..628
                     /gene="TSPY9"
                     /gene_synonym="TSPY9P"
                     /inference="alignment:Splign:2.1.0"
     exon            629..740
                     /gene="TSPY9"
                     /gene_synonym="TSPY9P"
                     /inference="alignment:Splign:2.1.0"
     exon            741..886
                     /gene="TSPY9"
                     /gene_synonym="TSPY9P"
                     /inference="alignment:Splign:2.1.0"
     exon            887..968
                     /gene="TSPY9"
                     /gene_synonym="TSPY9P"
                     /inference="alignment:Splign:2.1.0"
     exon            969..1179
                     /gene="TSPY9"
                     /gene_synonym="TSPY9P"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcccttcgc gcgcagtccc ttagggggcg cctggaagcc cggcgcatgc gccctgaggg
       61 ctcgctgacc taccgggtgc cagagaggct gcggcagggt ttctgtggcg tgggtcgggc
      121 agcacaggcc ttggtgtgtg cgagtgccaa ggagggcacc gccttcagga tggaggctgt
      181 acaggagggg gcggccgggg tggagagtga gcaggcggct ttgggggagg aggcggtgct
      241 gctgttggat gacataatgg cggaggtgga ggtggtggcg gaggtggagg tggtggcgga
      301 ggaggagggc ctcgtggagc ggcgggagga ggcccagcgg gcacagcagg ctgtgcctgg
      361 ccctgggccc atgaccccag agtctgcact ggaggagctg ctggccgttc aggtggagct
      421 ggagccggtt aatgcccaag ccaggaaggc cttttctcgg cagcgggaaa agatggagcg
      481 gaggcgcaag ccccagctag accgcagagg cgccgtcatc cagagcgtcc ctggcttctg
      541 ggccaatgtt attgcaaacc acccccagat gtcagccctg atcactgacg aagatgaaga
      601 catgctgagc tacatggtca gcctggaggt ggaagaagag aagcatcctg ttcatctctg
      661 caagatcatg ttgttctttc ggagtaaccc ctacttccag aataaagtga ttaccaagga
      721 atatctggtg aacatcacag aatacagggc ttctcattcc actccaattg agtggtatcc
      781 ggattatgaa gtggaggcct atcgccgcag acaccacaac agcagcctta acttcttcaa
      841 ctggttctct gaccacaact tcgcaggatc taacaagatt gctgagatcc tatgtaagga
      901 cctgtggcgc aatcccctgc aatactacaa gaggatgaag ccacctgaag agggaacaga
      961 gacgtcaggg gactcccagt tgttgagttg aatatgatgg agcatcagat tttacctaat
     1021 acagcagaac tcctaaaaag ttacagccat atgcaggacg gcagtactca gcatggtctt
     1081 atgcacagga actaaaggaa aaagagatcg agtcacaaaa attcaggaag agggggtaaa
     1141 tgtggattgt atggaatgaa aaataaacat tctcaagga
//
