LOCUS       NM_022573               1166 bp    mRNA    linear   PRI 07-APR-2024
DEFINITION  Homo sapiens testis specific protein Y-linked 2 (TSPY2), mRNA.
ACCESSION   NM_022573
VERSION     NM_022573.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1166)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 1166)
  AUTHORS   Ratti,A., Stuppia,L., Gatta,V., Fogh,I., Calabrese,G., Pizzuti,A.
            and Palka,G.
  TITLE     Characterization of a new TSPY gene family member in Yq (TSPYq1)
  JOURNAL   Cytogenet Cell Genet 88 (1-2), 159-162 (2000)
   PUBMED   10773691
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC006335.2.
            
            On Dec 30, 2020 this sequence version replaced NM_022573.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK307425.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000320701.9/ ENSP00000314077.4
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-532               AC006335.2         10324-10855
            533-610             AC006335.2         11457-11534
            611-722             AC006335.2         11663-11774
            723-868             AC006335.2         11876-12021
            869-950             AC006335.2         12128-12209
            951-1166            AC006335.2         12904-13119
FEATURES             Location/Qualifiers
     source          1..1166
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="Y"
                     /map="Yp11.2"
     gene            1..1166
                     /gene="TSPY2"
                     /gene_synonym="TSPYQ1"
                     /note="testis specific protein Y-linked 2"
                     /db_xref="GeneID:64591"
                     /db_xref="HGNC:HGNC:23924"
     exon            1..532
                     /gene="TSPY2"
                     /gene_synonym="TSPYQ1"
                     /inference="alignment:Splign:2.1.0"
     CDS             47..973
                     /gene="TSPY2"
                     /gene_synonym="TSPYQ1"
                     /note="testis-specific Y-encoded protein Q1"
                     /codon_start=1
                     /product="testis-specific Y-encoded protein 2"
                     /protein_id="NP_072095.2"
                     /db_xref="CCDS:CCDS35465.1"
                     /db_xref="GeneID:64591"
                     /db_xref="HGNC:HGNC:23924"
                     /translation="MRPEGSLTYRVPERLRQGSCGVGRAAQALVCASAKEGTAFRMEA
                     VQEGAAGVESEQAALGEEAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGP
                     MTPESALEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWA
                     NVIANHPQMSALITDEDEDMLSYMVSLEVEEEKHRVHLCKIMLFFRSNPYFQNKVITK
                     EYLVNITEYRASHSTPIEWYPDYEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEIL
                     CKDLWRNPLQYYKRMKPPEEGTETSGDSQLLS"
     exon            533..610
                     /gene="TSPY2"
                     /gene_synonym="TSPYQ1"
                     /inference="alignment:Splign:2.1.0"
     exon            611..722
                     /gene="TSPY2"
                     /gene_synonym="TSPYQ1"
                     /inference="alignment:Splign:2.1.0"
     exon            723..868
                     /gene="TSPY2"
                     /gene_synonym="TSPYQ1"
                     /inference="alignment:Splign:2.1.0"
     exon            869..950
                     /gene="TSPY2"
                     /gene_synonym="TSPYQ1"
                     /inference="alignment:Splign:2.1.0"
     exon            951..1166
                     /gene="TSPY2"
                     /gene_synonym="TSPYQ1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggctcttcgc gcgcagtccc ttagggggcg cctggaagcc cggcgcatgc gccctgaggg
       61 ctcgctgacc taccgggtgc cagagaggct gcggcagggt tcctgtggcg tgggtcgggc
      121 agcacaggcc ttggtgtgtg cgagtgccaa ggagggcacc gccttcagga tggaggctgt
      181 gcaggagggg gcggccgggg tggagagtga gcaggcggct ttgggggagg aggcggtgct
      241 gctgttggat gacataatgg cggaggtgga ggtggtggcg gaggaggagg gcctcgtgga
      301 gcggcgggag gaggcccagc gggcacagca ggctgtgcct ggccctgggc ccatgacccc
      361 agagtctgca ctggaggagc tgctggccgt tcaggtggag ctggagccgg ttaatgccca
      421 agccaggaag gccttttctc ggcagcggga aaagatggag cggaggcgca agccccacct
      481 agaccgcaga ggcgccgtca tccagagcgt ccctggcttc tgggccaatg ttattgcaaa
      541 ccacccccag atgtcagccc tgatcactga cgaagatgaa gacatgctga gctacatggt
      601 cagcctggag gtggaagaag agaagcatcg tgttcatctc tgcaagatca tgttgttctt
      661 tcggagtaac ccctacttcc agaataaagt gattaccaag gaatatctgg tgaacatcac
      721 agaatacagg gcttctcatt ccactccaat tgagtggtat ccggattatg aagtggaggc
      781 ctatcgccgc agacaccaca acagcagcct taacttcttc aactggttct ctgaccacaa
      841 cttcgcagga tctaacaaga ttgctgagat cctatgtaag gacctgtggc gcaatcccct
      901 gcaatactac aagaggatga agccacctga agagggaaca gagacgtcag gggactccca
      961 gttgttgagt tgaatatgat ggagcatcag attttaccta atacagcaga actcctaaaa
     1021 agttacagcc atatgcagga cagcagtact cagcatggtc ttatgcacag gaactaaagg
     1081 aaaaagagat cgagtcacaa aaattcagga agagggggta aatgtggatt gtatggaatg
     1141 aaaaataaac attctcaagg atgtgt
//
