LOCUS       NM_001100917            1018 bp    mRNA    linear   PRI 10-FEB-2024
DEFINITION  Homo sapiens tetraspanin 19 (TSPAN19), mRNA.
ACCESSION   NM_001100917 XM_084868 XM_940476
VERSION     NM_001100917.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1018)
  AUTHORS   Scherer,S.E., Muzny,D.M., Buhay,C.J., Chen,R., Cree,A., Ding,Y.,
            Dugan-Rocha,S., Gill,R., Gunaratne,P., Harris,R.A., Hawes,A.C.,
            Hernandez,J., Hodgson,A.V., Hume,J., Jackson,A., Khan,Z.M.,
            Kovar-Smith,C., Lewis,L.R., Lozado,R.J., Metzker,M.L.,
            Milosavljevic,A., Miner,G.R., Montgomery,K.T., Morgan,M.B.,
            Nazareth,L.V., Scott,G., Sodergren,E., Song,X.Z., Steffen,D.,
            Lovering,R.C., Wheeler,D.A., Worley,K.C., Yuan,Y., Zhang,Z.,
            Adams,C.Q., Ansari-Lari,M.A., Ayele,M., Brown,M.J., Chen,G.,
            Chen,Z., Clerc-Blankenburg,K.P., Davis,C., Delgado,O., Dinh,H.H.,
            Draper,H., Gonzalez-Garay,M.L., Havlak,P., Jackson,L.R.,
            Jacob,L.S., Kelly,S.H., Li,L., Li,Z., Liu,J., Liu,W., Lu,J.,
            Maheshwari,M., Nguyen,B.V., Okwuonu,G.O., Pasternak,S., Perez,L.M.,
            Plopper,F.J., Santibanez,J., Shen,H., Tabor,P.E., Verduzco,D.,
            Waldron,L., Wang,Q., Williams,G.A., Zhang,J., Zhou,J., Allen,C.C.,
            Amin,A.G., Anyalebechi,V., Bailey,M., Barbaria,J.A., Bimage,K.E.,
            Bryant,N.P., Burch,P.E., Burkett,C.E., Burrell,K.L., Calderon,E.,
            Cardenas,V., Carter,K., Casias,K., Cavazos,I., Cavazos,S.R.,
            Ceasar,H., Chacko,J., Chan,S.N., Chavez,D., Christopoulos,C.,
            Chu,J., Cockrell,R., Cox,C.D., Dang,M., Dathorne,S.R., David,R.,
            Davis,C.M., Davy-Carroll,L., Deshazo,D.R., Donlin,J.E., D'Souza,L.,
            Eaves,K.A., Simons,R., Emery-Cohen,A.J., Escotto,M., Flagg,N.,
            Forbes,L.D., Gabisi,A.M., Garza,M., Hamilton,C., Henderson,N.,
            Hernandez,O., Hines,S., Hogues,M.E., Huang,M., Idlebird,D.G.,
            Johnson,R., Jolivet,A., Jones,S., Kagan,R., King,L.M., Leal,B.,
            Lebow,H., Lee,S., LeVan,J.M., Lewis,L.C., London,P.,
            Lorensuhewa,L.M., Loulseged,H., Lovett,D.A., Lucier,A.,
            Lucier,R.L., Ma,J., Madu,R.C., Mapua,P., Martindale,A.D.,
            Martinez,E., Massey,E., Mawhiney,S., Meador,M.G., Mendez,S.,
            Mercado,C., Mercado,I.C., Merritt,C.E., Miner,Z.L., Minja,E.,
            Mitchell,T., Mohabbat,F., Mohabbat,K., Montgomery,B., Moore,N.,
            Morris,S., Munidasa,M., Ngo,R.N., Nguyen,N.B., Nickerson,E.,
            Nwaokelemeh,O.O., Nwokenkwo,S., Obregon,M., Oguh,M., Oragunye,N.,
            Oviedo,R.J., Parish,B.J., Parker,D.N., Parrish,J., Parks,K.L.,
            Paul,H.A., Payton,B.A., Perez,A., Perrin,W., Pickens,A.,
            Primus,E.L., Pu,L.L., Puazo,M., Quiles,M.M., Quiroz,J.B.,
            Rabata,D., Reeves,K., Ruiz,S.J., Shao,H., Sisson,I., Sonaike,T.,
            Sorelle,R.P., Sutton,A.E., Svatek,A.F., Svetz,L.A., Tamerisa,K.S.,
            Taylor,T.R., Teague,B., Thomas,N., Thorn,R.D., Trejos,Z.Y.,
            Trevino,B.K., Ukegbu,O.N., Urban,J.B., Vasquez,L.I., Vera,V.A.,
            Villasana,D.M., Wang,L., Ward-Moore,S., Warren,J.T., Wei,X.,
            White,F., Williamson,A.L., Wleczyk,R., Wooden,H.S., Wooden,S.H.,
            Yen,J., Yoon,L., Yoon,V., Zorrilla,S.E., Nelson,D.,
            Kucherlapati,R., Weinstock,G. and Gibbs,R.A.
  CONSRTM   Baylor College of Medicine Human Genome Sequencing Center Sequence
            Production Team
  TITLE     The finished DNA sequence of human chromosome 12
  JOURNAL   Nature 440 (7082), 346-351 (2006)
   PUBMED   16541075
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK126325.1, BX116902.1 and CB852874.1.
            
            On Nov 23, 2018 this sequence version replaced NM_001100917.1.
            
            ##Evidence-Data-START##
            CDS exon combination :: SRR5189667.142857.1, ERR279840.9212.1
                                    [ECO:0000331]
            RNAseq introns       :: single sample supports all introns
                                    SAMEA2148874, SAMEA2151119 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000532498.7/ ENSP00000433816.2
            RefSeq Select criteria :: based on longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-240               AK126325.1         1-240
            241-365             BX116902.1         222-346
            366-1018            CB852874.1         18-670              c
FEATURES             Location/Qualifiers
     source          1..1018
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12q21.31"
     gene            1..1018
                     /gene="TSPAN19"
                     /note="tetraspanin 19"
                     /db_xref="GeneID:144448"
                     /db_xref="HGNC:HGNC:31886"
     exon            1..74
                     /gene="TSPAN19"
                     /inference="alignment:Splign:2.1.0"
     exon            75..167
                     /gene="TSPAN19"
                     /inference="alignment:Splign:2.1.0"
     CDS             102..848
                     /gene="TSPAN19"
                     /note="putative tetraspanin-19; tspan-19"
                     /codon_start=1
                     /product="tetraspanin-19"
                     /protein_id="NP_001094387.1"
                     /db_xref="CCDS:CCDS44949.1"
                     /db_xref="GeneID:144448"
                     /db_xref="HGNC:HGNC:31886"
                     /translation="MLRNNKTIIIKYFLNLINGAFLVLGLLFMGFGAWLLLDRNNFLT
                     AFDENNHFIVPISQILIGMGSSTVLFCLLGYIGIHNEIRWLLIVYAVLITWTFAVQVV
                     LSAFIITKKEEVQQLWHDKIDFVISEYGSKDKPEDITKWTILNALQKTLQCCGQHNYT
                     DWIKNKNKENSGQVPCSCTKSTLRKWFCDEPLNATYLEGCENKISAWYNVNVLTLIGI
                     NFGLLTSEVFQVSLTVCFFKNIKNIIHAEM"
     exon            168..240
                     /gene="TSPAN19"
                     /inference="alignment:Splign:2.1.0"
     exon            241..365
                     /gene="TSPAN19"
                     /inference="alignment:Splign:2.1.0"
     exon            366..440
                     /gene="TSPAN19"
                     /inference="alignment:Splign:2.1.0"
     exon            441..551
                     /gene="TSPAN19"
                     /inference="alignment:Splign:2.1.0"
     exon            552..695
                     /gene="TSPAN19"
                     /inference="alignment:Splign:2.1.0"
     exon            696..779
                     /gene="TSPAN19"
                     /inference="alignment:Splign:2.1.0"
     exon            780..1018
                     /gene="TSPAN19"
                     /inference="alignment:Splign:2.1.0"
     regulatory      998..1003
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TSPAN19"
                     /note="hexamer: AATAAA"
     polyA_site      1018
                     /gene="TSPAN19"
                     /note="major polyA site"
ORIGIN      
        1 aaacaatctc gattctaaat tgaaacgaac gcagcatttc agggactgga tgaggagctt
       61 acggtttttt acagaatcat caatatcttg gaagaaaaag aatgttaaga aataacaaaa
      121 caataattat taagtacttt cttaatctca ttaatggagc tttcttggtt cttggacttt
      181 tattcatggg atttggtgca tggctcttat tagatagaaa taatttttta acagcttttg
      241 atgaaaataa tcacttcata gtacctattt ctcaaatttt gattggaatg ggatcttcta
      301 ctgttctttt ttgtctattg ggttatatag gaattcacaa cgaaatcaga tggctcctaa
      361 ttgtgtatgc agtattgata acatggacct ttgctgttca ggttgtactt tcagcattca
      421 tcatcacaaa gaaagaggag gttcagcaac tatggcatga caaaattgat tttgtcattt
      481 ctgagtatgg atctaaagat aagcctgaag atataaccaa gtggactatt ctgaatgcct
      541 tacagaaaac attacagtgt tgtggccaac ataattacac agactggata aagaataaga
      601 acaaagaaaa ttcaggacag gtgccatgtt cttgcacaaa gtcaacttta agaaaatggt
      661 tttgtgatga gccactgaat gcaacttacc ttgagggttg tgaaaataaa atcagtgcat
      721 ggtataatgt taatgtgtta accttaatcg gaattaactt tggactttta acttcagagg
      781 ttttccaagt ctcattaaca gtttgtttct tcaaaaacat caagaatata atccatgcag
      841 aaatgtgacc tttggatttc aatttgttca gaagaaacca gttaattctt aaaaaatcac
      901 attatattat tttattccaa aaacgttttg aattgtatta aataacagat gtattcaaat
      961 tattaattat atgtaatatt gaattactga atactataat aaaacattca tgaaatta
//
