LOCUS       NM_152762               1893 bp    mRNA    linear   PRI 08-APR-2024
DEFINITION  Homo sapiens testis specific 10 interacting protein (TSGA10IP),
            transcript variant 2, mRNA.
ACCESSION   NM_152762
VERSION     NM_152762.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1893)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 1893)
  AUTHORS   Fragoza,R., Das,J., Wierbowski,S.D., Liang,J., Tran,T.N., Liang,S.,
            Beltran,J.F., Rivera-Erick,C.A., Ye,K., Wang,T.Y., Yao,L., Mort,M.,
            Stenson,P.D., Cooper,D.N., Wei,X., Keinan,A., Schimenti,J.C.,
            Clark,A.G. and Yu,H.
  TITLE     Extensive disruption of protein interactions by genetic variants
            across the allele frequency spectrum in human populations
  JOURNAL   Nat Commun 10 (1), 4141 (2019)
   PUBMED   31515488
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AP006287.2 and KF459671.1.
            
            On Jul 9, 2021 this sequence version replaced NM_152762.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC104022.1, AK057442.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148874
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000532620.6/ ENSP00000484252.1
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-60                AP006287.2         60731-60790
            61-343              KF459671.1         1-283
            344-480             AP006287.2         62131-62267
            481-1199            AP006287.2         62361-63079
            1200-1347           AP006287.2         63252-63399
            1348-1518           AP006287.2         68818-68988
            1519-1618           AP006287.2         74134-74233
            1619-1743           AP006287.2         74441-74565
            1744-1893           AP006287.2         75068-75217
FEATURES             Location/Qualifiers
     source          1..1893
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q13.1"
     gene            1..1893
                     /gene="TSGA10IP"
                     /gene_synonym="FAM161C"
                     /note="testis specific 10 interacting protein"
                     /db_xref="GeneID:254187"
                     /db_xref="HGNC:HGNC:26555"
     exon            1..343
                     /gene="TSGA10IP"
                     /gene_synonym="FAM161C"
                     /inference="alignment:Splign:2.1.0"
     CDS             197..1867
                     /gene="TSGA10IP"
                     /gene_synonym="FAM161C"
                     /note="isoform b is encoded by transcript variant 2;
                     testis-specific protein 10-interacting protein;
                     tsga10-interacting protein"
                     /codon_start=1
                     /product="testis-specific protein 10-interacting protein
                     isoform b"
                     /protein_id="NP_689975.2"
                     /db_xref="CCDS:CCDS66138.1"
                     /db_xref="GeneID:254187"
                     /db_xref="HGNC:HGNC:26555"
                     /translation="MGQDTDMLNTYQQLVRTPSVRPGQDVRLQAPGTRTGLLKLLSTV
                     SQDKQGCLGSGDGVPNQDLQQRSQSSRQTAKKDRKPRGQSKKGQGSEESEDHFPLLPR
                     KPSFPFQWAWESIATDVRAVLQPSSPTPGHQALPMPSSFSQRQSRRKSTANLPEAHGC
                     CWKTEAQNLKARQQLGAWGGVSIPTGKGELGSEPPSGLQLPGRRPGSGSASDKQVQLQ
                     SLGAEEAERGLSSGVLPQRPRRGSISEEEQFSEATEEAEEGEHRTPCRRRAGCQRKGQ
                     ISGEEASDEGEVQGQSQGSSPSFNNLRRRQWRKTRAKELQGPWDLEKLHRQLQRDLDC
                     GPQKLPWKTLRAAFQASKRNGKAYASGYDETFVSANLPNRTFHKRQEATRSLLQAWER
                     QRQEERQQAELRRARTQHVQRQVAHCLAAYAPRGSRGPGAAQRKLEELRRQERQRFAE
                     YQAELQGIQHRVQARPFLFQQAMQANARLTVTRRFSQVLSALGLDEEQLLSEAGKVDR
                     EGTPRKPRSHRSMGVRMEHSPQRPPRTEPTGSQPDRHYNPSLDPECSP"
     exon            344..480
                     /gene="TSGA10IP"
                     /gene_synonym="FAM161C"
                     /inference="alignment:Splign:2.1.0"
     exon            481..1199
                     /gene="TSGA10IP"
                     /gene_synonym="FAM161C"
                     /inference="alignment:Splign:2.1.0"
     exon            1200..1347
                     /gene="TSGA10IP"
                     /gene_synonym="FAM161C"
                     /inference="alignment:Splign:2.1.0"
     exon            1348..1518
                     /gene="TSGA10IP"
                     /gene_synonym="FAM161C"
                     /inference="alignment:Splign:2.1.0"
     exon            1519..1618
                     /gene="TSGA10IP"
                     /gene_synonym="FAM161C"
                     /inference="alignment:Splign:2.1.0"
     exon            1619..1743
                     /gene="TSGA10IP"
                     /gene_synonym="FAM161C"
                     /inference="alignment:Splign:2.1.0"
     exon            1744..1893
                     /gene="TSGA10IP"
                     /gene_synonym="FAM161C"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1874..1879
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TSGA10IP"
                     /gene_synonym="FAM161C"
                     /note="hexamer: ATTAAA"
     polyA_site      1893
                     /gene="TSGA10IP"
                     /gene_synonym="FAM161C"
                     /note="major polyA site"
ORIGIN      
        1 ttgggcctgg gtctctgcgc taaatgactc ctgggcatcc tgctgaactc tctcccagaa
       61 ggagattggc ctcacatacc ccactgaccc cttcctagca tgctttttgc cagacccatt
      121 gagactggct gaggactggt tgccatagag atggcctgtt aggcagttct acggtgcgga
      181 tgggggatgg ggcaggatgg ggcaggacac cgatatgcta aatacctacc aacagttggt
      241 taggaccccg tcggtgcgac cagggcagga cgtgcggctc caggctccag gaaccagaac
      301 ggggctgctc aagctgctgt cgaccgtctc tcaggacaag cagggctgcc tggggagtgg
      361 tgatggtgtg ccaaatcaag acctgcagca gaggtctcag agctcaaggc agacagcaaa
      421 gaaggaccgc aagcccaggg gccagagcaa gaaaggacag ggctctgaag agtctgaaga
      481 tcacttcccg cttcttcctc ggaaaccctc cttccccttc cagtgggcct gggagagcat
      541 cgccacagat gtccgggctg tgcttcagcc aagctcccca acccctggcc accaagccct
      601 gcccatgccc tcctcgttct cccagcgtca gtccaggcgc aagtccacgg ccaacctccc
      661 agaggcccat ggctgctgct ggaagacaga ggcgcaaaac ctgaaggcga gacagcagct
      721 gggagcctgg ggcggtgtct ccatccctac tggcaaaggg gagctaggat cagagccccc
      781 cagtggtctc cagctgcctg ggaggaggcc aggatcagga tcggcgtccg acaagcaggt
      841 ccagctgcaa agcctgggtg ctgaggaggc cgagaggggt ctgagttctg gggtgctgcc
      901 ccagcgcccc aggagggggt cgatctcaga ggaggagcaa ttttcagagg ccacagagga
      961 ggctgaggag ggagagcaca ggactccctg cagaaggagg gctggttgtc agagaaaggg
     1021 gcagatttct ggagaggaag cctccgatga gggagaagtg cagggccaga gccaggggag
     1081 cagccccagc ttcaacaacc tccgaaggcg acaatggagg aagacaaggg ccaaggagct
     1141 gcaggggcca tgggacctgg agaagctgca caggcagcta cagagagacc tggactgtgg
     1201 cccccaaaag ctgccctgga agactttgag ggctgccttc caggcctcca agcggaatgg
     1261 aaaggcctat gcctcgggat acgatgaaac tttcgtgtct gccaacctcc ctaatcgcac
     1321 cttccacaaa cgacaggaag ccaccaggag cctgctgcag gcctgggagc ggcagcggca
     1381 ggaggagcgg cagcaggccg agctgcggcg ggcccggaca cagcatgtac agcggcaggt
     1441 ggcccactgc ctggcagcct acgcacccag agggagccgg ggccctgggg cggcccagcg
     1501 caagctggag gagctgaggc gccaggagcg acagcgcttt gctgagtacc aggcggagct
     1561 gcaaggcatc cagcacaggg tgcaggcccg gcccttcctg ttccagcagg ctatgcaggc
     1621 caatgcccgg ctcaccgtca ctcggcgctt ctcccaggtg ctgtcagcac tggggctgga
     1681 tgaggagcag ctgctgtctg aggcaggaaa ggtggacaga gagggcaccc ccaggaaacc
     1741 caggagccac aggtcaatgg gggtgagaat ggagcactct cctcagaggc ccccaaggac
     1801 agaacccacc ggcagccagc ctgacaggca ctacaacccc agcctggacc cggagtgcag
     1861 tccctgagat aaaattaaag gctttatggc aaa
//
