LOCUS       XM_047440978            3705 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens transient receptor potential cation channel
            subfamily M member 2 (TRPM2), transcript variant X4, mRNA.
ACCESSION   XM_047440978
VERSION     XM_047440978.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000021.9) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3705
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="21"
     gene            1..3705
                     /gene="TRPM2"
                     /gene_synonym="EREG1; KNP3; LTrpC-2; LTRPC2; NUDT9H;
                     NUDT9L1; TRPC7"
                     /note="transient receptor potential cation channel
                     subfamily M member 2; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 1 mRNA, 20 ESTs, 37 long
                     SRA reads, 1 Protein, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 1 sample
                     with support for all annotated introns"
                     /db_xref="GeneID:7226"
                     /db_xref="HGNC:HGNC:12339"
                     /db_xref="MIM:603749"
     CDS             81..3665
                     /gene="TRPM2"
                     /gene_synonym="EREG1; KNP3; LTrpC-2; LTRPC2; NUDT9H;
                     NUDT9L1; TRPC7"
                     /codon_start=1
                     /product="transient receptor potential cation channel
                     subfamily M member 2 isoform X4"
                     /protein_id="XP_047296934.1"
                     /db_xref="GeneID:7226"
                     /db_xref="HGNC:HGNC:12339"
                     /db_xref="MIM:603749"
                     /translation="MEPSALRKAGSEQEEGFEGLPRRVTDLGMVSNLRRSNSSLFKSW
                     RLQCPFGNNDKQESLSSWIPENIKKKECVYFVESSKLSDAGKVVCQCGYTHEQHLEEA
                     TKPHTFQGTQWDPKKHVQEMPTDAFGDIVFTGLSQKVKKYVRVSQDTPSSVIYHLMTQ
                     HWGLDVPNLLISVTGGAKNFNMKPRLKSIFRRGLVKVAQTTGAWIITGGSHTGVMKQV
                     GEAVRDFSLSSSYKEGELITIGVATWGTVHRREGLIHPTGSFPAEYILDEDGQGNLTC
                     LDSNHSHFILVDDGTHGQYGVEIPLRTRLEKFISEQTKERGGVAIKIPIVCVVLEGGP
                     GTLHTIDNATTNGTPCVVVEGSGRVADVIAQVANLPVSDITISLIQQKLSVFFQEMFE
                     TFTESRIVEWTKKIQDIVRRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHE
                     NWDHQLKLAVAWNRVDIARSEIFMDEWQWKPSDLHPTMTAALISNKPEFVKLFLENGV
                     QLKEFVTWDTLLYLYENLDPSCLFHSKLQKVLVEDPERPACAPAAPRLQMHHVAQVLR
                     ELLGDFTQPLYPRPRHNDRLRLLLPVPHVKLNVQGVSLRSLYKRSSGHVTFTMDPIRD
                     LLIWAIVQNRRELAGIIWAQSQDCIAAALACSKILKELSKEEEDTDSSEEMLALAEEY
                     EHRAIGVFTECYRKDEERAQKLLTRVSEAWGKTTCLQLALEAKDMKFVSHGGIQAFLT
                     KVWWGQLSVDNGLWRVTLCMLAFPLLLTGLISFREKRLQDVGTPAARARAFFTAPVVV
                     FHLNILSYFAFLCLFAYVLMVDFQPVPSWCECAIYLWLFSLVCEEMRQLFYDPDECGL
                     MKKAALYFSDFWNKLDVGAILLFVAGLTCRLIPATLYPGRVILSLDFILFCLRLMHIF
                     TISKTLGPKIIIVKRMMKDVFFFLFLLAVWVVSFGVAKQAILIHNERRVDWLFRGAVY
                     HSYLTIFGQIPGYIDGVNFNPEHCSPNGTDPYKPKCPESDATQQRPAFPEWLTVLLLC
                     LYLLFTNILLLNLLIAMFNYTFQQVQEHTDQIWKFQRHDLIEEYHGRPAAPPPFILLS
                     HLQLFIKRVVLKTPAKRHKQLKNKLEKNEEAALLSWEIYLKENYLQNRQFQQKQRPEQ
                     KIEDISNKTSAAQPSGSAMLSTVLPLSSSHLASFQGLTPWWTCWTWTH"
ORIGIN      
        1 agaaccccag tgtagcgagc tggagagagg actgtcctga gggcagcagg cctggttgca
       61 gctggcgtgg gggtctcaga atggagccct cagccctgag gaaagctggc tcggagcagg
      121 aggagggctt tgaggggctg cccagaaggg tcactgacct ggggatggtc tccaatctcc
      181 ggcgcagcaa cagcagcctc ttcaagagct ggaggctaca gtgccccttc ggcaacaatg
      241 acaagcaaga aagcctcagt tcgtggattc ctgaaaacat caagaagaaa gaatgcgtgt
      301 attttgtgga aagttccaaa ctgtctgatg ctgggaaggt ggtgtgtcag tgtggctaca
      361 cgcatgagca gcacttggag gaggctacca agccccacac cttccagggc acacagtggg
      421 acccaaagaa acatgtccag gagatgccaa ccgatgcctt tggcgacatc gtcttcacgg
      481 gcctgagcca gaaggtgaaa aagtacgtcc gagtctccca ggacacgccc tccagcgtga
      541 tctaccacct catgacccag cactgggggc tggacgtccc caatctcttg atctcggtga
      601 ccgggggggc caagaacttc aacatgaagc cgcggctgaa gagcattttc cgcagaggcc
      661 tggtcaaggt ggctcagacc acaggggcct ggatcatcac aggggggtcc cacaccggcg
      721 tcatgaagca ggtaggcgag gcggtgcggg acttcagcct gagcagcagc tacaaggaag
      781 gcgagctcat caccatcgga gtcgccacct ggggcactgt ccaccgccgc gagggcctga
      841 tccatcccac gggcagcttc cccgccgagt acatactgga tgaggatggc caagggaacc
      901 tgacctgcct agacagcaac cactctcact tcatcctcgt ggacgacggg acccacggcc
      961 agtacggggt ggagattcct ctgaggacca ggctggagaa gttcatatcg gagcagacca
     1021 aggaaagagg aggtgtggcc atcaagatcc ccatcgtgtg cgtggtgctg gagggcggcc
     1081 cgggcacgtt gcacaccatc gacaacgcca ccaccaacgg caccccctgt gtggttgtgg
     1141 agggctcggg ccgcgtggcc gacgtcattg cccaggtggc caacctgcct gtctcggaca
     1201 tcactatctc cctgatccag cagaaactga gcgtgttctt ccaggagatg tttgagacct
     1261 tcacggaaag caggattgtc gagtggacca aaaagatcca agatatcgtc cggaggcggc
     1321 agctgctgac tgtcttccgg gaaggcaagg atggtcagca ggacgtggat gtggccatct
     1381 tgcaggcctt gctgaaagcc tcacggagcc aagaccactt tggccacgag aactgggacc
     1441 accagctgaa actggcagtg gcatggaatc gcgtggacat tgcccgcagt gagatcttca
     1501 tggatgagtg gcagtggaag ccttcagatc tgcaccccac gatgacagct gcactcatct
     1561 ccaacaagcc tgagtttgtg aagctcttcc tggagaacgg ggtgcagctg aaggagtttg
     1621 tcacctggga caccttgctc tacctgtacg agaacctgga cccctcctgc ctgttccaca
     1681 gcaagctgca gaaggtgctg gtggaggatc ccgagcgccc ggcttgcgcg cccgcggcgc
     1741 cccgcctgca gatgcaccac gtggcccagg tgctgcggga gctgctgggg gacttcacgc
     1801 agccgcttta tccccggccc cggcacaacg accggctgcg gctcctgctg cccgttcccc
     1861 acgtcaagct caacgtgcag ggagtgagcc tccggtccct ctacaagcgt tcctcaggcc
     1921 atgtgacctt caccatggac cccatccgtg accttctcat ttgggccatt gtccagaacc
     1981 gtcgggagct ggcaggaatc atctgggctc agagccagga ctgcatcgca gcggccttgg
     2041 cctgcagcaa gatcctgaag gaactgtcca aggaggagga ggacacggac agctcggagg
     2101 agatgctggc gctggcggag gagtatgagc acagagccat cggggtcttc accgagtgct
     2161 accggaagga cgaagagaga gcccagaaac tgctcacccg cgtgtccgag gcctggggga
     2221 agaccacctg cctgcagctc gccctggagg ccaaggacat gaagtttgtg tctcacgggg
     2281 gcatccaggc cttcctgacc aaggtgtggt ggggccagct ctccgtggac aatgggctgt
     2341 ggcgtgtgac cctgtgcatg ctggccttcc cgctgctcct caccggcctc atctccttca
     2401 gggagaagag gctgcaggat gtgggcaccc ccgcggcccg cgcccgtgcc ttcttcaccg
     2461 cacccgtggt ggtcttccac ctgaacatcc tctcctactt cgccttcctc tgcctgttcg
     2521 cctacgtgct catggtggac ttccagcctg tgccctcctg gtgcgagtgt gccatctacc
     2581 tctggctctt ctccttggtg tgcgaggaga tgcggcagct cttctatgac cctgacgagt
     2641 gcgggctgat gaagaaggca gccttgtact tcagtgactt ctggaataag ctggacgtcg
     2701 gcgcaatctt gctcttcgtg gcagggctga cctgcaggct catcccggcg acgctgtacc
     2761 ccgggcgcgt catcctctct ctggacttca tcctgttctg cctccggctc atgcacattt
     2821 ttaccatcag taagacgctg gggcccaaga tcatcattgt gaagcggatg atgaaggacg
     2881 tcttcttctt cctcttcctg ctggctgtgt gggtggtgtc cttcggggtg gccaagcagg
     2941 ccatcctcat ccacaacgag cgccgggtgg actggctgtt ccgaggggcc gtctaccact
     3001 cctacctcac catcttcggg cagatcccgg gctacatcga cggtgtgaac ttcaacccgg
     3061 agcactgcag ccccaatggc accgacccct acaagcctaa gtgccccgag agcgacgcga
     3121 cgcagcagag gccggccttc cctgagtggc tgacggtcct cctactctgc ctctacctgc
     3181 tcttcaccaa catcctgctg ctcaacctcc tcatcgccat gttcaactac accttccagc
     3241 aggtgcagga gcacacggac cagatttgga agttccagcg ccatgacctg atcgaggagt
     3301 accacggccg ccccgccgcg ccgcccccct tcatcctcct cagccacctg cagctcttca
     3361 tcaagagggt ggtcctgaag actccggcca agaggcacaa gcagctcaag aacaagctgg
     3421 agaagaacga ggaggcggcc ctgctatcct gggagatcta cctgaaggag aactacctcc
     3481 agaaccgaca gttccagcaa aagcagcggc ccgagcagaa gatcgaggac atcagcaata
     3541 agacctcggc agcccagccc tcggggtcag ccatgctcag caccgtcctc cctctcagct
     3601 cctcccatct tgcttctttc caagggttga cgccatggtg gacctgctgg acctggaccc
     3661 actgaagagg tcgggctcca tggagcagag gttggcctcc ctgga
//
