LOCUS       XM_011532218            8398 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens transient receptor potential cation channel
            subfamily C member 3 (TRPC3), transcript variant X3, mRNA.
ACCESSION   XM_011532218
VERSION     XM_011532218.4
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000004.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011532218.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8398
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
     gene            1..8398
                     /gene="TRPC3"
                     /gene_synonym="SCA41; TRP3"
                     /note="transient receptor potential cation channel
                     subfamily C member 3; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 2 mRNAs, 7 ESTs, 48 long
                     SRA reads, 8 Proteins, and 93% coverage of the annotated
                     genomic feature by RNAseq alignments, including 3 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:7222"
                     /db_xref="HGNC:HGNC:12335"
                     /db_xref="MIM:602345"
     CDS             381..3143
                     /gene="TRPC3"
                     /gene_synonym="SCA41; TRP3"
                     /codon_start=1
                     /product="short transient receptor potential channel 3
                     isoform X3"
                     /protein_id="XP_011530520.1"
                     /db_xref="GeneID:7222"
                     /db_xref="HGNC:HGNC:12335"
                     /db_xref="MIM:602345"
                     /translation="MSTKVRKCKEQARVTFPAPEEEEDEGEDEGAEPQRRRRGWRGVN
                     GGLEPRSAPSQREPHGYCPPPFSHGPDLSMEGSPSLRRMTVMREKGRRQAVRGPAFMF
                     NDRGTSLTAEEERFLDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHL
                     EVTELLLKKENLARIGDALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDD
                     DFYAYDEDGTRFSPDITPIILAAHCQKYEVVHMLLMKGARIERPHDYFCKCGDCMEKQ
                     RHDSFSHSRSRINAYKGLASPAYLSLSSEDPVLTALELSNELAKLANIEKEFKNDYRK
                     LSMQCKDFVVGVLDLCRDSEEVEAILNGDLESAEPLEVHRHKASLSRVKLAIKYEVKK
                     FVAHPNCQQQLLTIWYENLSGLREQTIAIKCLVVLVVALGLPFLAIGYWIAPCSRLGK
                     ILRSPFMKFVAHAASFIIFLGLLVFNASDRFEGITTLPNITVTDYPKQIFRVKTTQFT
                     WTEMLIMVWVLGMMWSECKELWLEGPREYILQLWNVLDFGMLSIFIAAFTARFLAFLQ
                     ATKAQQYVDSYVQESDLSEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFS
                     RIAYILPANESFGPLQISLGRTVKDIFKFMVLFIMVFFAFMIGMFILYSYYLGAKVNA
                     AFTTVEESFKTLFWSIFGLSEVTSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNMLI
                     AMINSSYQEIEDDSDVEWKFARSKLWLSYFDDGKTLPPPFSLVPSPKSFVYFIMRIVN
                     FPKCRRRRLQKDIEMGMGNSKSRLNLFTQSNSRVFESHSFNSILNQPTRYQIMKRLIK
                     RYVLKAQVDKENDEVNEGELKEIKQDISSLRYELLEDKSQATEELAILIHKLSEKLNP
                     SMLRCE"
ORIGIN      
        1 gagtaacgat gctgtcctag caagtgatgc tgtcggagac aggagacggg cgccgaggag
       61 gcatcgccgc cgccgcgggg ctggagagcc tctcccagca ccagagcccc gctcggcccc
      121 gggcttcctc gtcgcagcca cggccgcggc agctgctccc acggtttgat ggtgggcggc
      181 ggcagctcgg cttcggcgct agcctctaac tgctggatcg cgggccgcga cgctctccgc
      241 tcctgccttc ccgccctggg ccgcccgggg ccccggaagc cgcgggaggt ggtgaagggg
      301 cgccgcggga agactgcact gccgcgaagg cggaggaggc cggcagccgg cacccccaca
      361 ctcggaccgc agccggcgcg atgtccacca aggtcaggaa gtgcaaagaa caagcaaggg
      421 tgaccttccc ggcgccggag gaggaggaag acgagggcga ggacgagggc gcggagccgc
      481 agcgccgccg ccggggctgg aggggcgtca acggggggct ggagccgcgc tcggcgccct
      541 cgcagcggga gccgcacggc tactgcccgc cgcccttctc ccacgggccg gacctgtcca
      601 tggagggaag cccatccctg agacgcatga cagtgatgcg ggagaagggc cggcgccagg
      661 ctgtcagggg cccggccttc atgttcaatg accgcggcac cagcctcacc gccgaggagg
      721 agcgcttcct cgacgccgcc gagtacggca acatcccagt ggtgcgcaag atgctggagg
      781 agtccaagac gctgaacgtc aactgcgtgg actacatggg ccagaacgcg ctgcagctgg
      841 ctgtgggcaa cgagcacctg gaggtgaccg agctgctgct caagaaggag aacctggcgc
      901 gcattggcga cgccctgctg ctcgccatca gcaagggcta cgtgcgcatc gtagaggcca
      961 tcctcaacca ccctggcttc gcggccagca agcgtctcac tctgagcccc tgtgagcagg
     1021 agctgcagga cgacgacttc tacgcttacg acgaggacgg cacgcgcttc tcgccggaca
     1081 tcacccccat catcctggcg gcgcactgcc agaaatacga agtggtgcac atgctgctga
     1141 tgaagggtgc caggatcgag cggccgcacg actatttctg caagtgcggg gactgcatgg
     1201 agaagcagag gcacgactcc ttcagccact cacgctcgag gatcaatgcc tacaaggggc
     1261 tggccagccc ggcttacctc tcattgtcca gcgaggaccc ggtgcttacg gccctagagc
     1321 tcagcaacga gctggccaag ctggccaaca tagagaagga gttcaagaat gactatcgga
     1381 agctctccat gcaatgcaaa gactttgtag tgggtgtgct ggatctctgc cgagactcag
     1441 aagaggtaga agccattctg aatggagatc tggaatcagc agagcctctg gaggtacaca
     1501 ggcacaaagc ttcattaagt cgtgtcaaac ttgccattaa gtatgaagtc aaaaagtttg
     1561 tggctcatcc caactgccag cagcagctct tgacgatctg gtatgagaac ctctcaggcc
     1621 taagggagca gaccatagct atcaagtgtc tcgttgtgct ggtcgtggcc ctgggccttc
     1681 cattcctggc cattggctac tggatcgcac cttgcagcag gctggggaaa attctgcgaa
     1741 gcccttttat gaagtttgta gcacatgcag cttctttcat catcttcctg ggtctgcttg
     1801 tgttcaatgc ctcagacagg ttcgaaggca tcaccacgct gcccaatatc acagttactg
     1861 actatcccaa acagatcttc agggtgaaaa ccacccagtt tacatggact gaaatgctaa
     1921 ttatggtctg ggttcttgga atgatgtggt ctgaatgtaa agagctctgg ctggaaggac
     1981 ctagggaata cattttgcag ttgtggaatg tgcttgactt tgggatgctg tccatcttca
     2041 ttgctgcttt cacagccaga ttcctagctt tccttcaggc aacgaaggca caacagtatg
     2101 tggacagtta cgtccaagag agtgacctca gtgaagtgac actcccacca gagatacagt
     2161 atttcactta tgctagagat aaatggctcc cttctgaccc tcagattata tctgaaggcc
     2221 tttatgccat agctgttgtg ctcagcttct ctcggattgc gtacatcctc cctgcaaatg
     2281 agagctttgg ccccctgcag atctctcttg gaaggactgt aaaggacata ttcaagttca
     2341 tggtcctctt tattatggtg ttttttgcct ttatgattgg catgttcata ctttattctt
     2401 actaccttgg ggctaaagtt aatgctgctt ttaccactgt agaagaaagt ttcaagactt
     2461 tattttggtc aatatttggg ttgtctgaag tgacttccgt tgtgctcaaa tatgatcaca
     2521 aattcataga aaatattgga tacgttcttt atggaatata caatgtaact atggtggtcg
     2581 ttttactcaa catgctaatt gctatgatta atagctcata tcaagaaatt gaggatgaca
     2641 gtgatgtaga atggaagttt gctcgttcaa aactttggtt atcctatttt gatgatggaa
     2701 aaacattacc tccacctttc agtctagttc ctagtccaaa atcatttgtt tatttcatca
     2761 tgcgaattgt taactttccc aaatgcagaa ggagaaggct tcagaaggat atagaaatgg
     2821 gaatgggtaa ctcaaagtcc aggttaaacc tcttcactca gtctaactca agagtttttg
     2881 aatcacacag ttttaacagc attctcaatc agccaacacg ttatcagata atgaaaagac
     2941 ttataaagcg gtatgttttg aaagcacaag tagacaaaga aaatgatgaa gttaatgaag
     3001 gtgaattaaa agaaatcaag caagatatct ccagccttcg ttatgaactt ttggaagaca
     3061 agagccaagc aactgaggaa ttagccattc taattcataa acttagtgag aaactgaatc
     3121 ccagcatgct gagatgtgaa tgatgcagca acctggattt ggctttgact atagcacaaa
     3181 tgtgggcaat aatatttcta agtatgaaat acttgaaaaa ctatgatgta aatttttagt
     3241 attaactacc tttatcatgt gaacctttaa aagttagctc ttaatggttt tattgtttta
     3301 tcacatgaaa atgcatttta tttgtctgct ttgacattac agtggcatac cattgtgttg
     3361 aaaagcccaa tattactata ttattgaaac ttttattcat tttagagtaa actccacatc
     3421 tttgcactac ctgtttgcct ccaagagact atcagttcct tggggacagg gaccatgtct
     3481 tattcatctt tgtgtctcca gcatctagta cagtgcctgg tatatagtag gtgctcaata
     3541 aatgttgaaa ccaactgaac tgccaacaaa ataaaaataa aaagtcttca ctatgtagca
     3601 taccttccct tgtccaagtt ctgaagaggt tttttttttt tttttttaat agaaactgaa
     3661 gacattttac aaccagctat gacttggtaa gacattctta gaattttagg tgtcactgat
     3721 aatcctagaa ccactgagcc ccaagtgaag aatttaacaa caaaatgggt taatgaaaaa
     3781 tataattaca ttgtatattt aagtttcata gaattattta aaacaacaca ttaaagattt
     3841 ttctaaaata tagactgctt gctttctgtc ttagacttac gtttgttgtt tttcagtaat
     3901 gtgattttct tttaagttgg gggttatgca gggttgtcat tttgttataa ccatctaatt
     3961 tctgcctctg ctgctttaat gctaaatgag atatcaacag ctgacttcat atctcacctg
     4021 tgagctccct gctgagtttt ggagggtctg ctcatgggaa gaaataggaa agagcagtga
     4081 ctatgggcgt acttggaaag acatggccaa gcatccccag gtgtgtttca gttccttttg
     4141 gggcatttat tgccatcgtt gcttacaatg attgacatct ttgtttctta tcaaaggatt
     4201 ccagttccac tttctatata aaatatattg tgatatatct acatatgcct tattacataa
     4261 ttgtgctgaa tgctggtaat atccgcaatg cctcttgact ttaatgggaa aaggcatgca
     4321 gaccagtaag ttccccagtc acttcagaga ctataaaaca ctcaaagcat tttttaacca
     4381 gctaggttta aatctctcat agagttatgt ttaacatcct gagtctgcag tcagttgctg
     4441 tcaagtcgta taggaatacg aattgtgatc atagatcaaa gattttcaga ggtccttaaa
     4501 accaactaaa tacatgctac tttaaaatca ttgctatcat gcagaaaagc tctttagaca
     4561 tgaagacaga aataagtgtt aaatggaact acataaagct ctttaaagat tatttcttaa
     4621 tttctacttt ttgggagtta aattaagaaa ggaactttat aaatgttttg ctaccattgt
     4681 agaacacttc attaactttt gtgccatgct aagagtattc gtcttaaaca tttttcaaac
     4741 tttatgtact ttatgttgtg tctcagaact gaataaaata ttgaattttt ccattgttat
     4801 atgttaccat atgttaagat agtaaagata caaagtttct ataatagatg tttctgatag
     4861 ttttatagta tggtccagga ttccaagtgt gaaaagtttt tgcttatagc tatggaactg
     4921 aatattttgt aattttcttc tttgcggttg gaaaaaatgt tgaatgaaaa agtggcagat
     4981 tcagctgggg acattcagcc taagattctt ggaatctgaa gatcagagaa gtatgaagat
     5041 aagcctcatg gtatccacac catgtggata aaaagctgac tttttttttt tttttttttt
     5101 gtccatgccc ctcacaactg tagagctctt aacaggcatt ttttctttat ttactatgta
     5161 caaactggta tagttttaat atttcatctt tttccttatt catcatttca aggtgttgtt
     5221 tcagaagaag gtgtgatgac aaggtgtagt gagtgtggtt gatgtttttg atgccctgcc
     5281 cagatgccct ctactggacc agtgcacctg tctcccagat tctcctgtgc agttcctagc
     5341 caatcacttc ccctggagaa ttgccctcag ctaaaaagaa gaagccttgc tcgggatgtg
     5401 atgcctccgc ctccccatgg ccagtgactg atgggtgggg gcacaaaggg ctggcccctt
     5461 gtctcaagat ggggccaact attcagtgca gttcatgctc cagagctcct gaaaggatta
     5521 gggtgatgcc agactcaagc tgagatgaaa tcctggttta gattcttcct ctgccttttc
     5581 cagtttcctt ccttcccttt ctccagagag catcccctta atgagtcacc acatccaaat
     5641 cttattaggt tttgctttta gggaactcac actaagccat aaggtattaa tgtggtagca
     5701 tacggttgag atgaggatta gtcgagggga ttgctgtcag aattagtcct tcacttgagg
     5761 ataaagatag ctctgggtca gcaagtcttt tccctagtca cttttaacag gtacctttgg
     5821 gaaaacaaac ctcaaagaag ttgttggggc aactcagaga agggagcatt taaacaggac
     5881 caaaaacaac tttatagaaa aaaacattaa ttaaaggatt gtcaaagccc caggactctt
     5941 ttttccttag gacatctctc attttttacc tctttgctat tcttattttt ttctcattta
     6001 cagataaaga aaagaaagca acactcaaag tgcttcttag acttattgtt cgaaaagttg
     6061 ggtactttgt aagtgcctgc tgtattgaat ttacagagca cccatgactt tatggaagtc
     6121 acaatctgtt gaaaagtttg ggttcttaga cttgaaataa tgagaaaact ttgaaaaatg
     6181 gtacagagta tctttacaga gtttatgcac aataaaaaca aaaatgatat gttgtgatta
     6241 ttaaaagcaa atttggtaca atttaggata actatcttac ccaatatgtc aatatattta
     6301 tatttcaaat gtgcaagcca agtgaaagca gcttttgtaa atgggaagat aaattgtctg
     6361 atggacaatg tctaaagaga actgaagcca cactaatgac tgtggtatgg gacaaaccat
     6421 ttaacttctc tggtcttcat aaatggttca ggcaaacagg gttatgctac atcaggggtt
     6481 cctagtccct ggagctcata gaggtgtttt aggaggttaa tgtcatcatc caaggtggta
     6541 atctttcttt ccatgtcttt ttaaattttt taaataaagt ttttaaaata catttttaga
     6601 ggcgggtctc actatgttgt ccaggctagt ctttaacttt tggcctcaag cgatcctcct
     6661 gcctcagcct cccaaaatca ggctgggcac agtggtgcac acctgtaatc gcagcacttt
     6721 gggacgttga agcaggtcga tggcttcagt tcaggagttc gagaccagca gggcaacatg
     6781 gtgaaactgt ctctacaaaa aatacaaaaa aaattagccg ggcatggtgg catgtgtctg
     6841 tggttccagt tactcaggag gctggggtga gaggataact tgagcccagg aagttgaggc
     6901 tgcagtgagc tggttcacgc cactgcactc cagcctgggt gacaaagtga accacccccc
     6961 acaaaaaaaa aaaaaaaaaa aaaaaaaaat ctaaaatggg tatttataac tttgttcagt
     7021 ttaaaaaaga gtttgagaat ttctaaattt ataccatgtg ttaggggaaa ctaatgtttt
     7081 tactcatgac tcagtcactc agctgaccac cactagcgtg ttgatggttt taactttaat
     7141 gcagtttaaa ttgcttttat ttttagccat aagttgttta acttatactc ataatggttg
     7201 ctttagcacc ataacataag gttataaatt actgaggtgc atggtaattc tgcaaatttg
     7261 tctctaaagt ggtctttgtc acatctgaga ggcagccatc ttctgttgag ttttataaag
     7321 accaccaaga tgtctctgat accctaaaac atctttaaaa agaggacaca cagtggtaat
     7381 ttaacttgac attttcttta ttgtgaataa aaattcctta ccctgctaat taattatttg
     7441 aggaatactt aaaattagta ggttgaaatc tttactaatc atttagaaac aaaacatagt
     7501 atgtacttta aaaataataa attgcatttt tagatgcaaa atcaaagaat tccaaatatc
     7561 atattatgca aactttttgt attgttttga tgctatatca tagcctcatt tcactgtttt
     7621 aaaataaatt tgagcttcaa aataaacttt tactttcctt ctacacaatt aattgaacag
     7681 tggacatcac ttgctaaatg gaaagtaagc actgccagca ttgtctgtct ttggtgtttt
     7741 tttttttacc tatttattag aaccatagta tttcttcatt attaatttgt atgaactatt
     7801 ttttaagata ttaactcttt tctcctatat ttttgttttc atttaaacat tgttgtgaca
     7861 tattgaaatg tttatcttta cttttcattt tttttaagtt agttttttgt ttgtttttta
     7921 gagatggggc cttgctattt tgcccaggct ggattgttgg gctcaagcaa tcttgagcct
     7981 cagccttcaa atagctgaga ctacaggcat gtaacaccat atctgctttt ttcctttgtg
     8041 gtttcttcta ttccttttga gatcagtttc cttctgttat gggctgaatt gtgtcccctc
     8101 aaaactcatg ttaaagtcct cgccttcagt atctcagact ataactatag ttggagatag
     8161 ggtctttaaa gaggtaatta atttaaaatg agataatatg actggtgtgc ttataaaaag
     8221 acaagatgag acacagacag acatagaggg aggaccacgt gaagacacgg agaagatgac
     8281 gatctataag ccaagaagag aggcctctga agatcggttt tattccctgc tgacaccttg
     8341 atctatgact tctagactcc aagactgtga gaaaataaat ttctgttgtt gaaaagcc
//
