LOCUS       XM_047449683            4918 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens tRNA methyltransferase 44 homolog (TRMT44),
            transcript variant X8, mRNA.
ACCESSION   XM_047449683
VERSION     XM_047449683.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000004.12) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4918
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
     gene            1..4918
                     /gene="TRMT44"
                     /gene_synonym="C4orf23; METTL19; TRM44"
                     /note="tRNA methyltransferase 44 homolog; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 6 ESTs, 125 long SRA reads, and 94% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     29 samples with support for all annotated introns"
                     /db_xref="GeneID:152992"
                     /db_xref="HGNC:HGNC:26653"
                     /db_xref="MIM:614309"
     CDS             47..2104
                     /gene="TRMT44"
                     /gene_synonym="C4orf23; METTL19; TRM44"
                     /codon_start=1
                     /product="probable tRNA (uracil-O(2)-)-methyltransferase
                     isoform X4"
                     /protein_id="XP_047305639.1"
                     /db_xref="GeneID:152992"
                     /db_xref="HGNC:HGNC:26653"
                     /db_xref="MIM:614309"
                     /translation="MAEVGRTGISYPGALLPQGFWAAVEVWLERPQVANKRLCGARLE
                     ARWSAALPCAEARGPGTSAGSEQKERGPGPGQGSPGGGPGPRSLSGPEQGTACCELEE
                     AQGQCQQEEAQREAASVPLRDSGHPGHAEGREGDFPAADLDSLWEDFSQSLARGNSEL
                     LAFLTSSGAGSQPEAQRELDVVLRTVIPKTSPHCPLTTPRREIVVQDVLNGTITFLPL
                     EEDDEGNLKVKMSNVYQIQLSHSKEEWFISVLIFCPERWHSDGIVYPKPTWLGEELLA
                     KLAKWSVENKKSDFKSTLSLISIMKYSKAYQELKEKYKEMVKVWPEVTDPEKFVYEDV
                     AIAAYLLILWEEERAERRLTARQSFVDLGCGNGLLVHILSSEGHPGRGIDVRRRKIWD
                     MYGPQTQLEEDAITPNDKTLFPDVDWLIGNHSDELTPWIPVIAARSSYNCRFFVLPCC
                     FFDFIGRYSRRQSKKTQYREYLDFIKEVGFTCGFHVDEDCLRIPSTKRVCLVGKSRTY
                     PSSREASVDEKRTQYIKSRRGCPVSPPGWELSPSPRWVAAGSAGHCDGQQALDARVGC
                     VTRAWAAEHGAGPQAEGPWLPGFHPREKAERVRNCAALPRDFIDQVVLQVANLLLGGK
                     QLNTRSSRNGSLKTWNGGESLSLAEVANELDTETLRRLKRECGGLQTLLRNSHQVFQD
                     AHL"
     polyA_site      4918
                     /gene="TRMT44"
                     /gene_synonym="C4orf23; METTL19; TRM44"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 gtcatctcgg cgcgccgctg ccagggctgt acacctgctg gctgccatgg ctgaggtggg
       61 ccgtaccggg atcagctacc caggcgcgct tctcccacag ggcttctggg ctgcggtcga
      121 agtgtggctg gagaggccgc aggtggcaaa caaacggctt tgcggcgccc gcctggaggc
      181 ccgctggagc gccgccctgc cctgcgcgga ggcccgcggc cccgggacta gcgcaggctc
      241 ggagcagaag gagcggggtc cgggacccgg ccagggttcc cccggagggg gcccgggtcc
      301 caggtcgcta tcaggacccg agcagggcac ggcatgttgc gaacttgagg aggcccaggg
      361 ccagtgccag caagaggagg cacagaggga agccgcctca gtgcccctga gggactccgg
      421 gcaccccggc catgctgaag gaagggaggg cgacttcccc gccgcagatc tggattcgct
      481 ttgggaggat ttctcccaaa gtctcgcccg tggcaattcg gagttgctgg ccttcctcac
      541 cagctccggg gcgggatcgc agccagaggc gcagcgtgag ctcgacgtgg ttctcagaac
      601 cgtcatcccg aaaactagcc cacattgccc ccttacaact cccaggaggg aaatagtcgt
      661 gcaagatgtc ctcaatggaa ccataacgtt tttgcctttg gaagaagatg atgaggggaa
      721 cctaaaggtt aagatgagca atgtgtatca aattcagctc agtcatagca aagaagaatg
      781 gttcatatct gttttaattt tctgtccaga aagatggcat tcagatggaa tcgtgtatcc
      841 caaacccacg tggcttggag aagagttgct ggccaagttg gccaagtggt ctgtagagaa
      901 caagaagagt gactttaaaa gcaccctttc cctcatctcc attatgaagt atagcaaggc
      961 ttaccaggaa cttaaagaga agtataagga aatggttaag gtgtggcctg aagtcactga
     1021 tcctgagaag ttcgtgtatg aagatgtggc tatcgcagca tacctgctga ttctatggga
     1081 agaagaaagg gctgagagga gactaactgc caggcagtcc tttgtggacc tgggatgtgg
     1141 aaatggcctc ctggtccaca tcctgagcag tgaggggcat ccaggcagag ggattgatgt
     1201 ccgaagaaga aaaatctggg acatgtatgg accacaaact cagttagagg aagatgcaat
     1261 cacacccaat gataagaccc ttttccctga tgttgattgg ttaatcggta accattctga
     1321 tgaactcaca ccatggatac ctgtcattgc agccaggtct tcctacaatt gccgcttctt
     1381 tgtcctcccc tgctgcttct ttgacttcat tggaagatac tcccggaggc agagtaagaa
     1441 gactcagtac cgggaatacc ttgacttcat taaagaagtg ggcttcacct gtgggtttca
     1501 cgtggacgaa gactgcctca ggattccttc aaccaaaaga gtctgtctcg ttggaaaatc
     1561 cagaacatac ccttcctcca gagaagcttc cgtggatgaa aagaggactc agtacattaa
     1621 gagcaggcgg ggctgccctg taagcccacc tggctgggag ctttcccctt ctccacgctg
     1681 ggttgctgct ggcagtgctg gtcactgtga cggtcagcaa gctctggacg ccagggtcgg
     1741 gtgtgtaacc agggcctggg ccgctgagca tggagcaggg ccccaggctg aaggaccctg
     1801 gctacctgga tttcatccca gagaaaaggc tgagcgtgtg aggaactgtg ccgccctgcc
     1861 acgagatttt attgaccaag tggttttgca agtagcgaat ttactgttag gtggaaagca
     1921 attaaacaca agaagttctc gaaatgggag tttgaagacc tggaatgggg gagagagcct
     1981 atctctggca gaagtagcca acgagctgga cacggagacc ctgcggaggc tgaagcggga
     2041 gtgtgggggc ctgcagacgc tgctccggaa cagccaccag gtgttccaag atgctcacct
     2101 gtgaagaggg agaacgtcgc tgtccgagca aatgtctctt ctgtgtcctt ggctgccttc
     2161 ctcctcctcc tcccgccgcc tactttgggg ccccttcctc ttctcagcag tgccactgac
     2221 cagcccagcc tcatgcacca tcccggccgt tgccctggag ggctggcagc tggcaggact
     2281 cagagagggc ccagccatca cccctctctt gagcagatga cagagtaaca ctgggagtta
     2341 ctatggacac tggaaaagag aacacagatg cgtcggagat tttgtagttg caactcttct
     2401 ctggtaacca aaaaacatca ggacattcat tgcaagtgca acgctgaggc tttgaaggaa
     2461 ccaaagagat cctttgcagc cctgaggacg gagggaggga gggaaaaggg agtggggtgg
     2521 gagggaggga gggagtccac tgcagaaagt ggcactgatc cctctgagcc tctccggcct
     2581 catgtgtaag atgccagctg ccccggagtg gcagtggcga gtgagtggct gtgtaaggtg
     2641 cccaggcagg agcttgcggg cagccctgtg tgaagtgggc agccttgggc cgggttccct
     2701 agaagcagag ctgagatggg gattcttgtt catgcgattg gaggtgcttc ctaagaagtt
     2761 gctccctgcc ccaactccga gccagggcag cactgaccat gggcaacttt cccttgcagg
     2821 gggcactccc agctgccggg gaggggcagt ggccctgaag gggcctggtc aggaccaaca
     2881 gttttcttgg cagtggtgtg tttgtcccca tttcgcagat gaggaaactg aggcttggaa
     2941 agacccaggt ccttgcccag gccccacacc acacccagga ggggcggcgc tggagtcctg
     3001 cgccacgtcg ctgttctcac caggaggagg cccttgtttg ctgcgtccag cgaccccatc
     3061 tccatgctgc aggcaggagg acacagccgg ggctcctgga agcctctcgc gttcctgggc
     3121 tagggaacct tcctccatct cagagccggc catggggtgt cccctgacct tccgcagcca
     3181 tgtccccctt cgatggagct ctgcttctgg ccctccctcc acactgaagg cccctgtgat
     3241 cacatggccc acccgccaat ccaggtggcc tccctccaag gtcagccggt gagctgcctt
     3301 catgcctgca tggtgtctct gacccttggc cacgcaacct aacatagtca caggtcctgg
     3361 agatttgcac tgggatatct tgggtgaggg gaattattct gctgaccccc gatggcaact
     3421 gcagtggtgg gaggggaaga gaacaccagg atgtgttcag agagagaggc gtggacctca
     3481 gggggtgtca ggggaagagg gcccgggagg gagaaagcat ttggtttaga cgtgttgggt
     3541 gtgaggtgcc catggaatag cagggtggag ctggtggggg aagctggggg gctgccctgg
     3601 ggctctagca catggaggcc aaggagggag tcgtggggtg gagggggcac agggctcccc
     3661 aaggtcctgg gtctgcctca gggccgctgc tactccacac ccctcctccc atgcctgagc
     3721 acccatggca gtgaccagca gtgaccatca tcacccaatg aggatggaga gaaactgagg
     3781 ctggcctgag atgtcctgag gaatgagctg gcaccagagt cccacaggtg aaggctgatg
     3841 aaattctagg agagtccatg tcctaaagga taagaagcaa ctattcgttg agatgagaga
     3901 cttcaaagat agtcaatgat cgtgaaagtc ggccagcctt tctggaccat ctcgtgcaat
     3961 tgctctaatc tatccctgca atagatccct ttaatacact ttgtcatatg ttgaattttc
     4021 tttttagttt ttagttttct tttgttgttg ttgttgtttt cccatttttt aaaattatta
     4081 ttattgtgga gacagagtct cactctgtca cccaggctgg agtgcggggg tgcgatctcg
     4141 gttcactgca ccctctgcct cccaggttca agcaattctc ctgcctcagc ctcctgagta
     4201 gctggggcta caggcacccg ccattatgtc tggctaattt ttgtattttt agtagagaca
     4261 gggtttcacc atgttggcca ggctcgtctc aaactcctga cctcaagtga tccgcccacc
     4321 tcggcctccc aaagtgttgg gattacaggc gtgagccacc acacccaggc ccattgtttt
     4381 taattatcaa cgttattttt gttattctat gtatttcatc tttgcatgat ttccagtatg
     4441 ggaggtataa attgtgtaaa gacgttgaga gttctaattt gttgtatgca ttttttacaa
     4501 atgtgactct gtgaaaatga ttatcacaac attgacttta tgtgtaagcg ttgtgtgtgt
     4561 gcgtacataa aatcgtcgaa acttcctcaa taaatgaaga gatgtccttt ttgtacgcct
     4621 gaatttatga aaggtaaatt tctcgaggtc ttgtttcttt gggcagctgc gtgtgcagtg
     4681 ctgacccatg agtgtctgat cgatcacgtc accagacgta gggtgtcctt catgggtttt
     4741 caaatgacag ctgttatctc aggaatttct ttatgaatgt ggtttgtctg ctcatcaccg
     4801 agtgtctatg cttgcaaaaa tatgtctgtt attactgcct attttattgt gtaaagtagc
     4861 ctgtgagatg ttccattgtg tttttgtttc ttaaataaat ctcctttaaa aatgtaaa
//
