LOCUS       NM_001031712            1843 bp    mRNA    linear   PRI 20-FEB-2025
DEFINITION  Homo sapiens tRNA methyltransferase 11 homolog (TRMT11), transcript
            variant 1, mRNA.
ACCESSION   NM_001031712
VERSION     NM_001031712.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1843)
  AUTHORS   Wang,C., Ulryck,N., Herzel,L., Pythoud,N., Kleiber,N.,
            Guerineau,V., Jactel,V., Moritz,C., Bohnsack,M.T., Carapito,C.,
            Touboul,D., Bohnsack,K.E. and Graille,M.
  TITLE     N 2-methylguanosine modifications on human tRNAs and snRNA U6 are
            important for cell proliferation, protein translation and pre-mRNA
            splicing
  JOURNAL   Nucleic Acids Res 51 (14), 7496-7519 (2023)
   PUBMED   37283053
  REMARK    Erratum:[Nucleic Acids Res. 2024 Jul 22;52(13):8033. doi:
            10.1093/nar/gkae524.. PMID: 38888115]
REFERENCE   2  (bases 1 to 1843)
  AUTHORS   Brumele,B., Mutso,M., Telanne,L., Ounap,K., Spunde,K., Abroi,A. and
            Kurg,R.
  TITLE     Human TRMT112-Methyltransferase Network Consists of Seven Partners
            Interacting with a Common Co-Factor
  JOURNAL   Int J Mol Sci 22 (24), 13593 (2021)
   PUBMED   34948388
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1843)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   4  (bases 1 to 1843)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   5  (bases 1 to 1843)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   6  (bases 1 to 1843)
  AUTHORS   Kohli,M., Riska,S.M., Mahoney,D.W., Chai,H.S., Hillman,D.W.,
            Rider,D.N., Costello,B.A., Qin,R., Lamba,J., Sahasrabudhe,D.M. and
            Cerhan,J.R.
  TITLE     Germline predictors of androgen deprivation therapy response in
            advanced prostate cancer
  JOURNAL   Mayo Clin Proc 87 (3), 240-246 (2012)
   PUBMED   22386179
  REMARK    GeneRIF: SNPs associated with androgen deprivation failure in
            advanced prostate cancer
REFERENCE   7  (bases 1 to 1843)
  AUTHORS   Elks,C.E., Perry,J.R., Sulem,P., Chasman,D.I., Franceschini,N.,
            He,C., Lunetta,K.L., Visser,J.A., Byrne,E.M., Cousminer,D.L.,
            Gudbjartsson,D.F., Esko,T., Feenstra,B., Hottenga,J.J.,
            Koller,D.L., Kutalik,Z., Lin,P., Mangino,M., Marongiu,M.,
            McArdle,P.F., Smith,A.V., Stolk,L., van Wingerden,S.H., Zhao,J.H.,
            Albrecht,E., Corre,T., Ingelsson,E., Hayward,C., Magnusson,P.K.,
            Smith,E.N., Ulivi,S., Warrington,N.M., Zgaga,L., Alavere,H.,
            Amin,N., Aspelund,T., Bandinelli,S., Barroso,I., Berenson,G.S.,
            Bergmann,S., Blackburn,H., Boerwinkle,E., Buring,J.E., Busonero,F.,
            Campbell,H., Chanock,S.J., Chen,W., Cornelis,M.C., Couper,D.,
            Coviello,A.D., d'Adamo,P., de Faire,U., de Geus,E.J., Deloukas,P.,
            Doring,A., Smith,G.D., Easton,D.F., Eiriksdottir,G., Emilsson,V.,
            Eriksson,J., Ferrucci,L., Folsom,A.R., Foroud,T., Garcia,M.,
            Gasparini,P., Geller,F., Gieger,C., Gudnason,V., Hall,P.,
            Hankinson,S.E., Ferreli,L., Heath,A.C., Hernandez,D.G., Hofman,A.,
            Hu,F.B., Illig,T., Jarvelin,M.R., Johnson,A.D., Karasik,D.,
            Khaw,K.T., Kiel,D.P., Kilpelainen,T.O., Kolcic,I., Kraft,P.,
            Launer,L.J., Laven,J.S., Li,S., Liu,J., Levy,D., Martin,N.G.,
            McArdle,W.L., Melbye,M., Mooser,V., Murray,J.C., Murray,S.S.,
            Nalls,M.A., Navarro,P., Nelis,M., Ness,A.R., Northstone,K.,
            Oostra,B.A., Peacock,M., Palmer,L.J., Palotie,A., Pare,G.,
            Parker,A.N., Pedersen,N.L., Peltonen,L., Pennell,C.E., Pharoah,P.,
            Polasek,O., Plump,A.S., Pouta,A., Porcu,E., Rafnar,T., Rice,J.P.,
            Ring,S.M., Rivadeneira,F., Rudan,I., Sala,C., Salomaa,V., Sanna,S.,
            Schlessinger,D., Schork,N.J., Scuteri,A., Segre,A.V.,
            Shuldiner,A.R., Soranzo,N., Sovio,U., Srinivasan,S.R.,
            Strachan,D.P., Tammesoo,M.L., Tikkanen,E., Toniolo,D., Tsui,K.,
            Tryggvadottir,L., Tyrer,J., Uda,M., van Dam,R.M., van Meurs,J.B.,
            Vollenweider,P., Waeber,G., Wareham,N.J., Waterworth,D.M.,
            Weedon,M.N., Wichmann,H.E., Willemsen,G., Wilson,J.F., Wright,A.F.,
            Young,L., Zhai,G., Zhuang,W.V., Bierut,L.J., Boomsma,D.I.,
            Boyd,H.A., Crisponi,L., Demerath,E.W., van Duijn,C.M., Econs,M.J.,
            Harris,T.B., Hunter,D.J., Loos,R.J., Metspalu,A., Montgomery,G.W.,
            Ridker,P.M., Spector,T.D., Streeten,E.A., Stefansson,K.,
            Thorsteinsdottir,U., Uitterlinden,A.G., Widen,E., Murabito,J.M.,
            Ong,K.K. and Murray,A.
  CONSRTM   GIANT Consortium
  TITLE     Thirty new loci for age at menarche identified by a meta-analysis
            of genome-wide association studies
  JOURNAL   Nat Genet 42 (12), 1077-1085 (2010)
   PUBMED   21102462
REFERENCE   8  (bases 1 to 1843)
  AUTHORS   Purushothaman,S.K., Bujnicki,J.M., Grosjean,H. and Lapeyre,B.
  TITLE     Trm11p and Trm112p are both required for the formation of
            2-methylguanosine at position 10 in yeast tRNA
  JOURNAL   Mol Cell Biol 25 (11), 4359-4370 (2005)
   PUBMED   15899842
REFERENCE   9  (bases 1 to 1843)
  AUTHORS   Rush,J., Moritz,A., Lee,K.A., Guo,A., Goss,V.L., Spek,E.J.,
            Zhang,H., Zha,X.M., Polakiewicz,R.D. and Comb,M.J.
  TITLE     Immunoaffinity profiling of tyrosine phosphorylation in cancer
            cells
  JOURNAL   Nat Biotechnol 23 (1), 94-101 (2005)
   PUBMED   15592455
REFERENCE   10 (bases 1 to 1843)
  AUTHORS   Mungall,A.J., Palmer,S.A., Sims,S.K., Edwards,C.A., Ashurst,J.L.,
            Wilming,L., Jones,M.C., Horton,R., Hunt,S.E., Scott,C.E.,
            Gilbert,J.G., Clamp,M.E., Bethel,G., Milne,S., Ainscough,R.,
            Almeida,J.P., Ambrose,K.D., Andrews,T.D., Ashwell,R.I.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Barker,D.J.,
            Barlow,K.F., Bates,K., Beare,D.M., Beasley,H., Beasley,O.,
            Bird,C.P., Blakey,S., Bray-Allen,S., Brook,J., Brown,A.J.,
            Brown,J.Y., Burford,D.C., Burrill,W., Burton,J., Carder,C.,
            Carter,N.P., Chapman,J.C., Clark,S.Y., Clark,G., Clee,C.M.,
            Clegg,S., Cobley,V., Collier,R.E., Collins,J.E., Colman,L.K.,
            Corby,N.R., Coville,G.J., Culley,K.M., Dhami,P., Davies,J.,
            Dunn,M., Earthrowl,M.E., Ellington,A.E., Evans,K.A., Faulkner,L.,
            Francis,M.D., Frankish,A., Frankland,J., French,L., Garner,P.,
            Garnett,J., Ghori,M.J., Gilby,L.M., Gillson,C.J., Glithero,R.J.,
            Grafham,D.V., Grant,M., Gribble,S., Griffiths,C., Griffiths,M.,
            Hall,R., Halls,K.S., Hammond,S., Harley,J.L., Hart,E.A.,
            Heath,P.D., Heathcott,R., Holmes,S.J., Howden,P.J., Howe,K.L.,
            Howell,G.R., Huckle,E., Humphray,S.J., Humphries,M.D., Hunt,A.R.,
            Johnson,C.M., Joy,A.A., Kay,M., Keenan,S.J., Kimberley,A.M.,
            King,A., Laird,G.K., Langford,C., Lawlor,S., Leongamornlert,D.A.,
            Leversha,M., Lloyd,C.R., Lloyd,D.M., Loveland,J.E., Lovell,J.,
            Martin,S., Mashreghi-Mohammadi,M., Maslen,G.L., Matthews,L.,
            McCann,O.T., McLaren,S.J., McLay,K., McMurray,A., Moore,M.J.,
            Mullikin,J.C., Niblett,D., Nickerson,T., Novik,K.L., Oliver,K.,
            Overton-Larty,E.K., Parker,A., Patel,R., Pearce,A.V., Peck,A.I.,
            Phillimore,B., Phillips,S., Plumb,R.W., Porter,K.M., Ramsey,Y.,
            Ranby,S.A., Rice,C.M., Ross,M.T., Searle,S.M., Sehra,H.K.,
            Sheridan,E., Skuce,C.D., Smith,S., Smith,M., Spraggon,L.,
            Squares,S.L., Steward,C.A., Sycamore,N., Tamlyn-Hall,G., Tester,J.,
            Theaker,A.J., Thomas,D.W., Thorpe,A., Tracey,A., Tromans,A.,
            Tubby,B., Wall,M., Wallis,J.M., West,A.P., White,S.S.,
            Whitehead,S.L., Whittaker,H., Wild,A., Willey,D.J., Wilmer,T.E.,
            Wood,J.M., Wray,P.W., Wyatt,J.C., Young,L., Younger,R.M.,
            Bentley,D.R., Coulson,A., Durbin,R., Hubbard,T., Sulston,J.E.,
            Dunham,I., Rogers,J. and Beck,S.
  TITLE     The DNA sequence and analysis of human chromosome 6
  JOURNAL   Nature 425 (6960), 805-811 (2003)
   PUBMED   14574404
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC056878.1 and AF532977.1.
            
            On Nov 23, 2018 this sequence version replaced NM_001031712.2.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (a).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF532977.1, SRR3476690.36675.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000334379.11/ ENSP00000333934.5
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-699               BC056878.1         111-809
            700-1843            AF532977.1         775-1918
FEATURES             Location/Qualifiers
     source          1..1843
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6q22.32"
     gene            1..1843
                     /gene="TRMT11"
                     /gene_synonym="C6orf75; MDS024; TRM11; TRMT11-1"
                     /note="tRNA methyltransferase 11 homolog"
                     /db_xref="GeneID:60487"
                     /db_xref="HGNC:HGNC:21080"
     exon            1..83
                     /gene="TRMT11"
                     /gene_synonym="C6orf75; MDS024; TRM11; TRMT11-1"
                     /inference="alignment:Splign:2.1.0"
     CDS             12..1403
                     /gene="TRMT11"
                     /gene_synonym="C6orf75; MDS024; TRM11; TRMT11-1"
                     /EC_number="2.1.1.-"
                     /note="isoform a is encoded by transcript variant 1; tRNA
                     guanosine-2'-O-methyltransferase TRM11 homolog; tRNA
                     (guanine(10)-N2)-methyltransferase homolog; tRNA
                     (guanine(10)-N(2))-methyltransferase homolog"
                     /codon_start=1
                     /product="tRNA (guanine(10)-N(2))-methyltransferase
                     homolog isoform a"
                     /protein_id="NP_001026882.2"
                     /db_xref="CCDS:CCDS35496.1"
                     /db_xref="GeneID:60487"
                     /db_xref="HGNC:HGNC:21080"
                     /translation="MALSCTLNRYLLLMAQEHLEFRLPEIKSLLLLFGGQFASSQETY
                     GKSPFWILSIPSEDIARNLMKRTVCAKSIFELWGHGQSPEELYSSLKNYPVEKMVPFL
                     HSDSTYKIKIHTFNKTLTQEEKIKRIDALEFLPFEGKVNLKKPQHVFSVLEDYGLDPN
                     CIPENPHNIYFGRWIADGQRELIESYSVKKRHFIGNTSMDAGLSFIMANHGKVKENDI
                     VFDPFVGTGGLLIACAHFGAYVYGTDIDYNTVHGLGKATRKNQKWRGPDENIRANLRQ
                     YGLEKYYLDVLVSDASKPSWRKGTYFDAIITDPPYGIRESTRRTGSQKEIPKGIEKWE
                     KCPESHVPVSLSYHLSDMFLDLLNFAAETLVLGGRLVYWLPVYTPEYTEEMVPWHPCL
                     ELVSNCEQKLSSHTSRRLITMEKVKKFENRDQYSHLLSDHFLPYQGHNSFREKYFSGV
                     TKRIAKEEKSTQE"
     exon            84..149
                     /gene="TRMT11"
                     /gene_synonym="C6orf75; MDS024; TRM11; TRMT11-1"
                     /inference="alignment:Splign:2.1.0"
     exon            150..223
                     /gene="TRMT11"
                     /gene_synonym="C6orf75; MDS024; TRM11; TRMT11-1"
                     /inference="alignment:Splign:2.1.0"
     exon            224..305
                     /gene="TRMT11"
                     /gene_synonym="C6orf75; MDS024; TRM11; TRMT11-1"
                     /inference="alignment:Splign:2.1.0"
     exon            306..398
                     /gene="TRMT11"
                     /gene_synonym="C6orf75; MDS024; TRM11; TRMT11-1"
                     /inference="alignment:Splign:2.1.0"
     exon            399..533
                     /gene="TRMT11"
                     /gene_synonym="C6orf75; MDS024; TRM11; TRMT11-1"
                     /inference="alignment:Splign:2.1.0"
     exon            534..690
                     /gene="TRMT11"
                     /gene_synonym="C6orf75; MDS024; TRM11; TRMT11-1"
                     /inference="alignment:Splign:2.1.0"
     exon            691..771
                     /gene="TRMT11"
                     /gene_synonym="C6orf75; MDS024; TRM11; TRMT11-1"
                     /inference="alignment:Splign:2.1.0"
     exon            772..936
                     /gene="TRMT11"
                     /gene_synonym="C6orf75; MDS024; TRM11; TRMT11-1"
                     /inference="alignment:Splign:2.1.0"
     exon            937..1018
                     /gene="TRMT11"
                     /gene_synonym="C6orf75; MDS024; TRM11; TRMT11-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1019..1150
                     /gene="TRMT11"
                     /gene_synonym="C6orf75; MDS024; TRM11; TRMT11-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1151..1271
                     /gene="TRMT11"
                     /gene_synonym="C6orf75; MDS024; TRM11; TRMT11-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1272..1843
                     /gene="TRMT11"
                     /gene_synonym="C6orf75; MDS024; TRM11; TRMT11-1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1817..1822
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TRMT11"
                     /gene_synonym="C6orf75; MDS024; TRM11; TRMT11-1"
                     /note="hexamer: AATAAA"
     polyA_site      1843
                     /gene="TRMT11"
                     /gene_synonym="C6orf75; MDS024; TRM11; TRMT11-1"
                     /note="major polyA site"
ORIGIN      
        1 gggcagctgc aatggcgctg tcgtgtaccc ttaacaggta tctgctcctc atggcgcagg
       61 agcatctgga gttccgcctg ccggaaataa agtctttgct tttgcttttt ggaggtcagt
      121 ttgccagcag tcaagaaact tatggaaagt caccattttg gattcttagc attccctctg
      181 aagatattgc aagaaatttg atgaaacgga cagtgtgtgc caagtctata tttgaactat
      241 ggggtcatgg acaatctcct gaggagctgt acagttctct taaaaactac cctgtggaga
      301 agatggttcc atttctacat tcggactcta catataaaat aaagattcac acttttaata
      361 agacattgac acaagaagag aaaatcaagc gaatagatgc acttgaattt ctgccatttg
      421 aaggaaaagt gaatttaaag aaaccgcaac atgtattttc tgttttggag gattatggtt
      481 tagacccaaa ctgcatccct gagaatccac ataatattta ttttggtaga tggattgcag
      541 atggacagag agagcttatt gagtcataca gtgtcaaaaa gagacacttt attggaaata
      601 caagtatgga tgctggtttg tcattcatta tggctaacca tggaaaagtg aaagaaaatg
      661 atattgtctt tgatccattt gttggaacag gtggcctgct gatagcatgt gctcattttg
      721 gtgcatatgt gtatgggaca gacatagact acaacacagt tcatggcttg ggaaaggcta
      781 ctaggaaaaa ccagaagtgg agaggaccag atgaaaacat tagggccaat cttcgtcaat
      841 atggtttaga gaagtattac cttgatgtcc tggtttcaga tgcatctaaa ccttcctgga
      901 ggaagggcac atattttgat gcaatcatta ctgatcctcc atatggtatc agagaatcta
      961 caagaagaac aggttcacag aaggagatac caaaggggat agaaaaatgg gaaaaatgtc
     1021 cagaaagcca tgttcctgtt tccttgagtt atcatctgag tgatatgttt cttgacctgt
     1081 taaacttcgc agctgagacc ctcgttttag gtggaagact agtctattgg ttaccggtgt
     1141 atacgccaga atacactgaa gagatggtgc cttggcaccc ttgcctggaa ctcgttagca
     1201 actgcgagca gaagctttcc agtcacacat caaggcgctt gatcacaatg gaaaaggtga
     1261 agaaatttga gaatcgggac cagtattcac atctgctaag tgatcatttt ctgccatacc
     1321 aaggtcataa ttccttccgt gagaaatatt ttagtggggt aacaaaaaga attgccaagg
     1381 aagaaaaatc cacccaggaa tgaaaattaa gattttgaca atgaagaaag aataagaatt
     1441 tgatttaaaa agacatctgg atgtgaactt tcatgtatga tccagaaaat aggtacggtt
     1501 ttaaaatatt ttatatagaa aagctacaaa gtaaattgag caatgctttt aaagttatct
     1561 ttgttttata gacttttttg ttgtatgtat tacagtcttt ataatcttat ttaatgtata
     1621 tttgtacttt caagtactga tggagataga ctcaaaacag ttattttttt acaattaatc
     1681 tacaaaggga attaatattg ttgactttta aaacatctgc tggatatatt atatgcaatt
     1741 aatagtagtt aagaatttat tcatttggta gatatgttta tttggttttt ggttgtcatc
     1801 gatttacatt gccactaata aaccatattg agaatttcta aaa
//
