LOCUS       NM_001171797            3667 bp    mRNA    linear   PRI 10-FEB-2024
DEFINITION  Homo sapiens triple QxxK/R motif containing (TRIQK), transcript
            variant 2, mRNA.
ACCESSION   NM_001171797
VERSION     NM_001171797.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3667)
  AUTHORS   Onuma,Y., Watanabe,A., Aburatani,H., Asashima,M. and Whitman,M.
  TITLE     TRIQK, a novel family of small proteins localized to the
            endoplasmic reticulum membrane, is conserved across vertebrates
  JOURNAL   Zoolog Sci 25 (7), 706-713 (2008)
   PUBMED   18828657
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DA093687.1, DQ351291.1, BC110326.1 and BQ009934.1.
            
            On May 17, 2019 this sequence version replaced NM_001171797.1.
            
            Transcript Variant: This variant (2) differs in the 5' UTR,
            compared to variant 1. Variants 1-7 all encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803614.132819.1,
                                           SRR1803616.253836.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2145240, SAMEA2145544
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000521988.6/ ENSP00000429517.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-28                DA093687.1         1-28
            29-823              DQ351291.1         1-795
            824-3566            BC110326.1         788-3530
            3567-3667           BQ009934.1         21-121              c
FEATURES             Location/Qualifiers
     source          1..3667
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="8"
                     /map="8q22.1"
     gene            1..3667
                     /gene="TRIQK"
                     /gene_synonym="C8orf83; PRO0845; UPF0599"
                     /note="triple QxxK/R motif containing"
                     /db_xref="GeneID:286144"
                     /db_xref="HGNC:HGNC:27828"
     exon            1..138
                     /gene="TRIQK"
                     /gene_synonym="C8orf83; PRO0845; UPF0599"
                     /inference="alignment:Splign:2.1.0"
     exon            139..297
                     /gene="TRIQK"
                     /gene_synonym="C8orf83; PRO0845; UPF0599"
                     /inference="alignment:Splign:2.1.0"
     exon            298..379
                     /gene="TRIQK"
                     /gene_synonym="C8orf83; PRO0845; UPF0599"
                     /inference="alignment:Splign:2.1.0"
     CDS             319..579
                     /gene="TRIQK"
                     /gene_synonym="C8orf83; PRO0845; UPF0599"
                     /note="protein TRIQK; triple repetitive-sequence of QXXK/R
                     protein homolog"
                     /codon_start=1
                     /product="triple QxxK/R motif-containing protein"
                     /protein_id="NP_001165268.1"
                     /db_xref="CCDS:CCDS55261.1"
                     /db_xref="GeneID:286144"
                     /db_xref="HGNC:HGNC:27828"
                     /translation="MGRKDAATIKLPVDQYRKQIGKQDYKKTKPILRATKLKAEAKKT
                     AIGIKEVGLVLAAILALLLAFYAFFYLRLTTDVDPDLDQDED"
     exon            380..465
                     /gene="TRIQK"
                     /gene_synonym="C8orf83; PRO0845; UPF0599"
                     /inference="alignment:Splign:2.1.0"
     exon            466..3667
                     /gene="TRIQK"
                     /gene_synonym="C8orf83; PRO0845; UPF0599"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1839..1844
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TRIQK"
                     /gene_synonym="C8orf83; PRO0845; UPF0599"
                     /note="hexamer: AATAAA"
     polyA_site      1867
                     /gene="TRIQK"
                     /gene_synonym="C8orf83; PRO0845; UPF0599"
     regulatory      3641..3646
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TRIQK"
                     /gene_synonym="C8orf83; PRO0845; UPF0599"
                     /note="hexamer: AATAAA"
     polyA_site      3667
                     /gene="TRIQK"
                     /gene_synonym="C8orf83; PRO0845; UPF0599"
                     /note="major polyA site"
ORIGIN      
        1 ctcttttccg cctcaccctt tgggagtagg ggtgtgcggc tggcttgtcc cgcccctgcc
       61 cctgagtgac agaaccgtgg acagcaacat ttcccacagg acacgaagtt tgtcggccct
      121 tgccttggca gagctgagta agaaaaatca ccaagaatat tatttttggt atttggaatt
      181 gaatttgcca ggaatgcaag cactgctacc taactaaaga ccttggcttt ggaaacatct
      241 taccccttgg cagctctcca gagtttagac ttggcagcat caaagacaca acgcaagcag
      301 gcattttgga gatcaaagat gggtagaaaa gatgctgcta ctataaaact tcctgttgat
      361 cagtacagaa aacaaattgg taaacaggat tataaaaaaa ctaaacctat tttacgagca
      421 accaaattaa aagcagaagc aaagaaaaca gcaataggca taaaggaagt tggccttgta
      481 cttgcagcta tattggcact actactggct ttctatgctt tcttttatct cagactcacc
      541 acggatgttg accctgatct ggaccaagat gaagattagc taagcaacaa tcaatgcatg
      601 aaagagaaat aactttacga aagcaccttt tgggaccaaa actttcaata ctgaaactgt
      661 aacatcttta attctttctg ctaatatttt cagtttgcag acatatgatt tttgatagtt
      721 gcataggatg tcaggaaaag aaccttacct agcaatgcag tatagtatgt gctactggat
      781 acttttatat atctttctgc tttgacagcc accctataca tggtacattt agatgaaatg
      841 ggaaccagat cctaaatttt tcaaatgtca ttgccaattt atgtgtataa ttccatcact
      901 tcctgatgag taagtctatt tttgttctat atacatcata agttagtata tattcttatt
      961 tacagaaaca tgctcaaatc acattcagaa agaacaaaaa gtcatgggaa attttttatt
     1021 ttacaacaaa gccctgcttt ctttctggac gtattttaca tcattagaga gactatctgc
     1081 acatacatct accataatct ttttccttct ttgccaactg ttcagtgcac atgtgctgca
     1141 tcagaaatgg cacctggatg acagaagctc aaagagtcac atatgtctct aaaatagagt
     1201 tcttttcctc ttgggctgtc tgaactggtg taaatagaag ctcagttgat cttggtttta
     1261 attaacttat tactctatta atataacctt ggaattctat tctaattatg ttgttctggc
     1321 tgcttgtagt atcagttcgc ccctcttgtt agggagatat gtaacaatct gtcatttaat
     1381 tgagcagtct ttttcacata acagtaatag caaaaatcct acctactcag aatcatcttc
     1441 ttaggttgtc tcctaaatct gaacaataca gttgttttat aaaattacat tttgtctctt
     1501 gagatttaat caattagaac tctttaggga gaaaataaat aatagaagaa aatatatgcc
     1561 tcatatttca tatgtaatta tctgttgata taatttttca atgtattttg tatttgtggg
     1621 agcataatga cctgtacatt caatattttt actggtaatt caatttttaa atatgttttt
     1681 acaatgcttg aacacataaa ccttagaaaa ctggaaaata cgtgtccaca gaaagagtta
     1741 ttagctacta ccttatgtaa agatgcatag aaaatgaaat tgttggaaac atgtgcacaa
     1801 agtgttttat attatataca ttgtatttat gaagaataaa taaaatatta agattgtttt
     1861 cctgctagcc aagagaagaa atccttggga aatatctaag gagtatatgg ggctttataa
     1921 gcactgtttc taaaagatat tctctggtac ttttgcaaaa agtcgactgt gactgtgtag
     1981 cattatgttc tgtagaattt ttttcaagta gcataattta tttcattggt gtgaaaacag
     2041 ccaaaggttc caatatcctc acaaatcatt tatgccaaac atctgagggc aaaatttagc
     2101 cggtgttatt tactagattc ttccctttga actcacagac tcaagagaca gaccaagagt
     2161 tcttatatac tcaccacagc ggaccaatcc aagtggcatt tttaggaaag gttgcagcat
     2221 ttaatgccat gtggtatgtc tgttcgtcaa gtgggtggca agggaatatc caagctggca
     2281 ttttggatat gatgggcctt ttactttcct gagtgacatg ccacatgtca agaaatactg
     2341 ctccccaccc ccccactccc atcacattta cgtgaacaat tttcatttag ttatttcccg
     2401 ttccatatgg tgttaaaaca gtcgtattaa ataaagatta tttctagttt tcagtggtaa
     2461 tttaaatgag aggatatgta ataattgctt attagatact tatccaaatg aaatataaca
     2521 gagtttacag tacttaaaat ggctggttat ggtcttggaa atgtttgaaa attcattatc
     2581 ctgaaaaaaa ctttaccatt ctgttttacc cttgaggtat tttttgggga aaaatgtttt
     2641 tgataactat taatctaaat atagtataat tataggcaaa tttcactgcc tagttttatt
     2701 gatatcctga gtctacagct agtccattcg tatgactgat tgatttatga tagctccaga
     2761 gaaccataaa tttcaaaggc taaactctct gattttagta aatagtaggt aaagtgacac
     2821 aatatatgtt tacacaacac tgttttcatg aaatgcaaac tttgcaaaac tcacattaac
     2881 tgggaagcag ccaaccctct gtagagaaat cccagattgg gagtctggtt tgaatctttg
     2941 aagacagaaa ggtgatatcc ggcctgctgt tttaaaggga ccacactttt gaatacctac
     3001 tggtgtttgg cagaaatctg agactggcac cagacacaaa ttttagacat gggtatcttc
     3061 cctccagtaa ttcactgctc agagtaattt agaagacaaa aacagaaaaa attgtaatga
     3121 ttttttaagt gttagaatat gtttgttaac atactctgca aaataaattt caactaatgc
     3181 aatagactta aaatatagcc tatggaatac tgtgattgaa gtttgaaggc ttgctggttc
     3241 ttattttgca tgcaagttta gacagggtaa agaatgtata aatttatttg agatgagata
     3301 cagtattgta aaaatataac ctcatctaga attgctttta aaacaagcaa aagcctattt
     3361 tagtacaaat gtagggtggg tagttgtttt aaggtagcaa aatacttcaa gattttctat
     3421 ctttttaatt tttcatgaag acagaagaaa tactttcacc ccaaccaatg actgtaagat
     3481 cttgagagta tgttcttact catttctgta attgcagtag tgtagtcatc tgcatataaa
     3541 tttaataaat gcatgttaaa atttaagttg atgcctttta gtcctctcag agtctgtcac
     3601 agtttctttg tgtaaatgat aaaaaagttt gaatttaatc aataaaactt aaaaatcaca
     3661 atatcaa
//
