LOCUS       NM_001146162            1353 bp    mRNA    linear   PRI 29-JUL-2024
DEFINITION  Homo sapiens tripartite motif containing 77 (TRIM77), transcript
            variant 1, mRNA.
ACCESSION   NM_001146162 XM_001717744 XM_936301
VERSION     NM_001146162.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1353)
  AUTHORS   Han,K., Lou,D.I. and Sawyer,S.L.
  TITLE     Identification of a genomic reservoir for new TRIM genes in primate
            genomes
  JOURNAL   PLoS Genet 7 (12), e1002388 (2011)
   PUBMED   22144910
REFERENCE   2  (bases 1 to 1353)
  AUTHORS   Taylor,T.D., Noguchi,H., Totoki,Y., Toyoda,A., Kuroki,Y., Dewar,K.,
            Lloyd,C., Itoh,T., Takeda,T., Kim,D.W., She,X., Barlow,K.F.,
            Bloom,T., Bruford,E., Chang,J.L., Cuomo,C.A., Eichler,E.,
            FitzGerald,M.G., Jaffe,D.B., LaButti,K., Nicol,R., Park,H.S.,
            Seaman,C., Sougnez,C., Yang,X., Zimmer,A.R., Zody,M.C.,
            Birren,B.W., Nusbaum,C., Fujiyama,A., Hattori,M., Rogers,J.,
            Lander,E.S. and Sakaki,Y.
  TITLE     Human chromosome 11 DNA sequence and analysis including novel gene
            identification
  JOURNAL   Nature 440 (7083), 497-500 (2006)
   PUBMED   16554811
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AP003122.2, JF968446.1 and JF968445.1.
            
            On or before Apr 1, 2009 this sequence version replaced
            XM_936301.1, XM_001717744.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            transcript and genomic sequence to make the sequence consistent
            with the reference genome assembly. The genomic coordinates used
            for the transcript record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMEA2149178 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000398290.7/ ENSP00000474003.1
            RefSeq Select criteria    :: based on expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-351               AP003122.2         62131-62481
            352-453             JF968446.1         1-102
            454-890             JF968445.1         1-437
            891-1353            AP003122.2         69242-69704
FEATURES             Location/Qualifiers
     source          1..1353
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q14.3"
     gene            1..1353
                     /gene="TRIM77"
                     /gene_synonym="TRIM77P"
                     /note="tripartite motif containing 77"
                     /db_xref="GeneID:390231"
                     /db_xref="HGNC:HGNC:34228"
     CDS             1..1353
                     /gene="TRIM77"
                     /gene_synonym="TRIM77P"
                     /note="isoform 1 is encoded by transcript variant 1;
                     putative tripartite motif-containing protein 77; putative
                     tripartite motif-containing protein 64D; TRIM77-isoform;
                     tripartite motif containing 77, pseudogene"
                     /codon_start=1
                     /product="tripartite motif-containing protein 77 isoform
                     1"
                     /protein_id="NP_001139634.1"
                     /db_xref="CCDS:CCDS60929.1"
                     /db_xref="GeneID:390231"
                     /db_xref="HGNC:HGNC:34228"
                     /translation="MASAITQCSTSELTCSICTDYLTDPVTICCGHRFCSPCLCLLWE
                     DTLTPNCCPVCREISQQMYFKRIIFAEKQVIPTRESVPCQLSSSAMLICRRHQEIKNL
                     ICETDRSLLCFLCSQSPRHATHKHYMTREADEYYRKKLLIQMKSIWKKKQKNQRNLNR
                     ETNIIGTWEVFINLRSMMISAEYPKVCQYLREEEQKHVESLAREGRIIFQQLKRSQTR
                     MAKMGILLREMYEKLKEMSCKADVNLPQDLGDVMKRNEFLRLAMPQPVNPQLSAWTIT
                     GVSERLNFFRVYITLDRKICSNHKLLFEDLRHLQCSLDDTDMSCNPTSTQYTSSWGAQ
                     ILSSGKHYWEVDVKDSCNWVIGLCREAWTKRNDMRLDSEGIFLLLCLKVDDHFSLFST
                     SPLLPHYIPRPQGWLGVFLDYECGIVSFVNVAQSSLICSFLSRIFYFPLRPFICHGSK
                     "
     exon            1..411
                     /gene="TRIM77"
                     /gene_synonym="TRIM77P"
                     /inference="alignment:Splign:2.1.0"
     exon            412..507
                     /gene="TRIM77"
                     /gene_synonym="TRIM77P"
                     /inference="alignment:Splign:2.1.0"
     exon            508..738
                     /gene="TRIM77"
                     /gene_synonym="TRIM77P"
                     /inference="alignment:Splign:2.1.0"
     exon            739..761
                     /gene="TRIM77"
                     /gene_synonym="TRIM77P"
                     /inference="alignment:Splign:2.1.0"
     exon            762..859
                     /gene="TRIM77"
                     /gene_synonym="TRIM77P"
                     /inference="alignment:Splign:2.1.0"
     exon            860..1353
                     /gene="TRIM77"
                     /gene_synonym="TRIM77P"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggcttctg ctatcacgca gtgttctacc agtgagctca cctgctcgat ctgcacagac
       61 tatttgacag accctgtcac catttgttgt gggcacagat tttgtagtcc ctgtctctgc
      121 ctcttgtggg aagatacact aactcctaat tgctgccctg tgtgcaggga aatatcacag
      181 caaatgtact tcaaacgcat tatttttgct gagaaacaag ttattcctac aagagaatca
      241 gtcccctgcc agttatcaag ctctgccatg ctgatctgta ggagacacca ggaaatcaag
      301 aacctcatct gtgaaactga taggagcctg ctgtgttttc tatgctctca atccccaagg
      361 catgctactc acaaacacta tatgacaagg gaggctgatg aatactatag gaagaaactc
      421 ctgattcaaa tgaagtccat ctggaaaaaa aaacagaaaa atcaaagaaa tctaaacaga
      481 gagaccaaca taatcggaac atgggaagtt tttataaatt tgcggagcat gatgatcagt
      541 gctgaatatc ctaaggtgtg tcaatacctc cgtgaagaag agcaaaagca cgtagagagc
      601 ctggcaagag aaggcaggat aatttttcag caactcaaga gaagtcaaac tagaatggct
      661 aagatgggta tactcctgag agaaatgtat gagaaactga aggaaatgag ctgtaaagca
      721 gatgtgaacc tgcctcagga tttgggagac gtaatgaaaa ggaatgagtt tctgaggctg
      781 gccatgcctc agcctgtgaa cccacagctc agtgcatgga ccatcactgg ggtgtcagaa
      841 aggcttaact tcttcagagt gtatatcacc ttggatcgta agatatgcag taatcacaag
      901 cttctgttcg aagacctaag gcatttgcag tgcagccttg atgatacaga catgtcctgt
      961 aatccaacaa gtacacagta tacttcttca tggggagctc agatcctcag ctctggcaaa
     1021 cattactggg aggtggatgt gaaagactct tgtaattggg ttataggact ttgcagagaa
     1081 gcctggacaa agaggaatga catgcgactt gactctgagg gtatctttct actcctgtgt
     1141 ctcaaagtgg atgaccattt cagtctcttc tctacctccc cactgttacc tcactatatt
     1201 ccaaggcccc aaggctggct aggggtgttc ctggattatg aatgtgggat agtgagcttt
     1261 gttaatgttg cccaaagttc cctcatttgt agtttcctct cacgcatctt ctattttcct
     1321 ctcagacctt tcatttgcca cggatctaaa taa
//
