LOCUS       NM_032681               1629 bp    mRNA    linear   PRI 01-JUN-2024
DEFINITION  Homo sapiens tripartite motif-containing 51 (TRIM51), mRNA.
ACCESSION   NM_032681
VERSION     NM_032681.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1629)
  AUTHORS   Han,K., Lou,D.I. and Sawyer,S.L.
  TITLE     Identification of a genomic reservoir for new TRIM genes in primate
            genomes
  JOURNAL   PLoS Genet 7 (12), e1002388 (2011)
   PUBMED   22144910
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC036111.7, DV080293.1 and BC005014.1.
            
            On May 17, 2019 this sequence version replaced NM_032681.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA1968968, SAMEA2145743
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000449290.6/ ENSP00000395086.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-88                AC036111.7         37766-37853         c
            89-386              AC036111.7         35428-35725         c
            387-902             DV080293.1         1-516
            903-1629            BC005014.1         543-1269
FEATURES             Location/Qualifiers
     source          1..1629
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q12.1"
     gene            1..1629
                     /gene="TRIM51"
                     /gene_synonym="SPRYD5; TRIM51A"
                     /note="tripartite motif-containing 51"
                     /db_xref="GeneID:84767"
                     /db_xref="HGNC:HGNC:19023"
     exon            1..88
                     /gene="TRIM51"
                     /gene_synonym="SPRYD5; TRIM51A"
                     /inference="alignment:Splign:2.1.0"
     exon            89..503
                     /gene="TRIM51"
                     /gene_synonym="SPRYD5; TRIM51A"
                     /inference="alignment:Splign:2.1.0"
     CDS             93..1451
                     /gene="TRIM51"
                     /gene_synonym="SPRYD5; TRIM51A"
                     /note="SPRY domain-containing protein 5; SPRY domain
                     containing 5"
                     /codon_start=1
                     /product="tripartite motif-containing protein 51"
                     /protein_id="NP_116070.2"
                     /db_xref="GeneID:84767"
                     /db_xref="HGNC:HGNC:19023"
                     /translation="MNSGILQVFQRALTCPICMNYFLDPVTIDCGHSFCRPCLYLNWQ
                     DTAVLAQCSECKKTTRQRNLNTDICLKNMAFIARKASLRQFLSSEEQICGMHRETKKM
                     FCEVDKSLLCLPCSNSQEHRNHIHCPIEWAAEERREELLKKMQSLWEKACENLRNLNM
                     ETTRTRCWKDYVSLRIEAIRAEYQKMPAFLHEEEQHHLERLRKEGEDIFQQLNESKAR
                     MEHSRELLRGMYEDLKQMCHKADVELLQAFGDILHRYESLLLQVSEPVNPELSAGPIT
                     GLLDSLSGFRVDFTLQPERANSHIFLCGDLRSMNVGCDPQDDPDITGKSECFLVWGAQ
                     AFTSGKYYWEVHMGDSWNWAFGVCNNYWKEKRQNDKIDGEEGLFLLGCVKEDTHCSLF
                     TTSPLVVQYVPRPTSTVGLFLDCEGRTVSFVDVDQSSLIYTIPNCSFSPPLRPIFCCS
                     HF"
     exon            504..599
                     /gene="TRIM51"
                     /gene_synonym="SPRYD5; TRIM51A"
                     /inference="alignment:Splign:2.1.0"
     exon            600..830
                     /gene="TRIM51"
                     /gene_synonym="SPRYD5; TRIM51A"
                     /inference="alignment:Splign:2.1.0"
     exon            831..853
                     /gene="TRIM51"
                     /gene_synonym="SPRYD5; TRIM51A"
                     /inference="alignment:Splign:2.1.0"
     exon            854..951
                     /gene="TRIM51"
                     /gene_synonym="SPRYD5; TRIM51A"
                     /inference="alignment:Splign:2.1.0"
     exon            952..1629
                     /gene="TRIM51"
                     /gene_synonym="SPRYD5; TRIM51A"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1605..1610
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TRIM51"
                     /gene_synonym="SPRYD5; TRIM51A"
                     /note="hexamer: ATTAAA"
     polyA_site      1629
                     /gene="TRIM51"
                     /gene_synonym="SPRYD5; TRIM51A"
                     /note="major polyA site"
ORIGIN      
        1 gcagggaatg agctcctgat cttggggagt acttaaaaga attttttctt ggaagaatta
       61 ctgcaggaaa cattcataga accttgggaa acatgaattc tggaatcttg caagtcttcc
      121 agagggcact cacctgtccc atctgcatga actacttcct agacccagtc accatagact
      181 gtgggcacag cttttgccgg ccctgtttgt acctcaactg gcaagacacg gcagttcttg
      241 ctcagtgctc tgaatgcaag aagacaacgc ggcagagaaa cctcaacact gacatttgtt
      301 tgaagaacat ggctttcatt gccagaaaag ccagcctccg gcaattcctt agctctgagg
      361 agcaaatatg tgggatgcac agagagacaa agaagatgtt ctgtgaagtg gacaagagcc
      421 tgctctgttt gccgtgctcc aactctcagg agcaccggaa tcacatacac tgtcccattg
      481 agtgggctgc tgaggaacgc cgggaggagc tcctaaaaaa aatgcagtct ttatgggaaa
      541 aagcttgtga aaatctcaga aatctgaaca tggaaaccac aagaaccaga tgctggaagg
      601 attatgtgag tttaaggata gaagcaatca gagctgaata tcagaagatg cctgcatttc
      661 tccatgaaga agagcaacat cacttggaaa ggctgcgaaa ggagggcgag gacatttttc
      721 agcaactcaa tgaaagcaaa gccagaatgg aacattccag ggagctttta agaggaatgt
      781 atgaggatct gaagcaaatg tgccataaag cagatgtgga gctactccag gcttttggag
      841 acatattaca caggtatgag tctctgctgc tgcaagtgtc tgagcctgtg aatccagagc
      901 tcagtgcagg gcccatcact ggactgctgg acagcctcag tggattcaga gttgatttta
      961 ctctgcagcc tgaaagagcc aatagtcata tcttcctgtg tggagatttg agaagcatga
     1021 atgttggatg tgaccctcaa gatgatcccg atatcactgg aaaatctgaa tgttttcttg
     1081 tatggggggc tcaggctttc acatctggca aatattattg ggaggttcat atgggggact
     1141 cttggaattg ggcttttggt gtctgtaaca attattggaa agagaagaga cagaatgaca
     1201 agatagatgg agaggaggga ctctttcttc ttggatgtgt taaggaggac actcactgca
     1261 gtctctttac cacctcccca cttgtggtgc aatatgttcc aagacctacc agcacagtag
     1321 gattattcct ggattgtgaa ggtagaaccg tgagctttgt tgatgttgat caaagttccc
     1381 tgatatacac catccccaat tgctccttct cacctcctct caggcctatc ttttgctgta
     1441 gtcacttctg accagagaaa agtcagaaat gtgcctgtat gctctgggaa cctgtttatc
     1501 ccagaaagcc ctctttttcg cacctcatca aacagaacaa ataagttata tttaatgtct
     1561 ttagttgcat tctaatgtca tcaaaactca tttatagtgt ttctattaaa tatggtgaaa
     1621 acattaaaa
//
