LOCUS       NM_001384911            2146 bp    mRNA    linear   PRI 09-JUN-2024
DEFINITION  Homo sapiens tripartite motif containing 49D1 (TRIM49D1),
            transcript variant 2, mRNA.
ACCESSION   NM_001384911 XM_011542816
VERSION     NM_001384911.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2146)
  AUTHORS   Han,K., Lou,D.I. and Sawyer,S.L.
  TITLE     Identification of a genomic reservoir for new TRIM genes in primate
            genomes
  JOURNAL   PLoS Genet 7 (12), e1002388 (2011)
   PUBMED   22144910
REFERENCE   2  (bases 1 to 2146)
  AUTHORS   Taylor,T.D., Noguchi,H., Totoki,Y., Toyoda,A., Kuroki,Y., Dewar,K.,
            Lloyd,C., Itoh,T., Takeda,T., Kim,D.W., She,X., Barlow,K.F.,
            Bloom,T., Bruford,E., Chang,J.L., Cuomo,C.A., Eichler,E.,
            FitzGerald,M.G., Jaffe,D.B., LaButti,K., Nicol,R., Park,H.S.,
            Seaman,C., Sougnez,C., Yang,X., Zimmer,A.R., Zody,M.C.,
            Birren,B.W., Nusbaum,C., Fujiyama,A., Hattori,M., Rogers,J.,
            Lander,E.S. and Sakaki,Y.
  TITLE     Human chromosome 11 DNA sequence and analysis including novel gene
            identification
  JOURNAL   Nature 440 (7083), 497-500 (2006)
   PUBMED   16554811
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AP004607.4 and AP005814.2.
            
            On Jul 1, 2020 this sequence version replaced XM_011542816.3.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA1968968, SAMEA2144335
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000420869.3/ ENSP00000474678.1
            RefSeq Select criteria    :: based on manual assertion,
                                         conservation, expression, longest
                                         protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-394               AP004607.4         8356-8749           c
            395-605             AP004607.4         6803-7013           c
            606-1020            AP004607.4         3804-4218           c
            1021-1116           AP004607.4         3423-3518           c
            1117-1347           AP004607.4         1416-1646           c
            1348-1370           AP004607.4         679-701             c
            1371-1468           AP005814.2         34916-35013         c
            1469-2146           AP005814.2         33121-33798         c
FEATURES             Location/Qualifiers
     source          1..2146
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q14.3"
     gene            1..2146
                     /gene="TRIM49D1"
                     /gene_synonym="TRIM49D; TRIM49D1P; TRIM49D2; TRIM49D2P;
                     TRIM49DP"
                     /note="tripartite motif containing 49D1"
                     /db_xref="GeneID:399939"
                     /db_xref="HGNC:HGNC:43973"
     exon            1..394
                     /gene="TRIM49D1"
                     /gene_synonym="TRIM49D; TRIM49D1P; TRIM49D2; TRIM49D2P;
                     TRIM49DP"
                     /inference="alignment:Splign:2.1.0"
     exon            395..605
                     /gene="TRIM49D1"
                     /gene_synonym="TRIM49D; TRIM49D1P; TRIM49D2; TRIM49D2P;
                     TRIM49DP"
                     /inference="alignment:Splign:2.1.0"
     exon            606..1020
                     /gene="TRIM49D1"
                     /gene_synonym="TRIM49D; TRIM49D1P; TRIM49D2; TRIM49D2P;
                     TRIM49DP"
                     /inference="alignment:Splign:2.1.0"
     CDS             610..1968
                     /gene="TRIM49D1"
                     /gene_synonym="TRIM49D; TRIM49D1P; TRIM49D2; TRIM49D2P;
                     TRIM49DP"
                     /note="tripartite motif containing 49D, pseudogene;
                     tripartite motif containing 49D1, pseudogene; tripartite
                     motif-containing protein 49-like protein; tripartite
                     motif-containing protein 49D2 pseudogene; tripartite
                     motif-containing protein 49D1"
                     /codon_start=1
                     /product="tripartite motif-containing protein 49D"
                     /protein_id="NP_001371840.1"
                     /db_xref="CCDS:CCDS60930.1"
                     /db_xref="GeneID:399939"
                     /db_xref="HGNC:HGNC:43973"
                     /translation="MNSGISQVFQRELTCPICLNYFIDPVTIDCGHSFCRPCFYLNWQ
                     DIPILTQCFECLKTTQQRNLKTNIRLKKMASRARKASLWLFLSSEEQMCGTHRETKKI
                     FCEVDRSLLCLLCSSSLEHRYHRHCPAEWAAEEHREKLLKKMQSLWEKVCENQRNLNV
                     ETTRISHWKDYVNVRLEAIRAEYQKMPAFHHEEEKHNLEMLKKKGKDIFHRLHLSKAK
                     MAHRREILRGTYAELMKMCHKPDVELLQAFGDILHRSESVLLHMPQPLNLELRAGPIT
                     GLRDRLNQFRVDITLPHNEANSHIFRRGDLRSICIGCDRQNAPHITATPTSFLAWGAQ
                     TFTSGKYYWEVHVGDSWNWAFGVCNKYWKGTNQNGNIHGEEGLFSLGCVKNDIQCSLF
                     TTSPLTLQYVPRPTNHVGLFLDCEARTVSFVDVNQSSPIHTIPNCSFSPPLRPIFCCV
                     HL"
     exon            1021..1116
                     /gene="TRIM49D1"
                     /gene_synonym="TRIM49D; TRIM49D1P; TRIM49D2; TRIM49D2P;
                     TRIM49DP"
                     /inference="alignment:Splign:2.1.0"
     exon            1117..1347
                     /gene="TRIM49D1"
                     /gene_synonym="TRIM49D; TRIM49D1P; TRIM49D2; TRIM49D2P;
                     TRIM49DP"
                     /inference="alignment:Splign:2.1.0"
     exon            1348..1370
                     /gene="TRIM49D1"
                     /gene_synonym="TRIM49D; TRIM49D1P; TRIM49D2; TRIM49D2P;
                     TRIM49DP"
                     /inference="alignment:Splign:2.1.0"
     exon            1371..1468
                     /gene="TRIM49D1"
                     /gene_synonym="TRIM49D; TRIM49D1P; TRIM49D2; TRIM49D2P;
                     TRIM49DP"
                     /inference="alignment:Splign:2.1.0"
     exon            1469..2146
                     /gene="TRIM49D1"
                     /gene_synonym="TRIM49D; TRIM49D1P; TRIM49D2; TRIM49D2P;
                     TRIM49DP"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2122..2127
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TRIM49D1"
                     /gene_synonym="TRIM49D; TRIM49D1P; TRIM49D2; TRIM49D2P;
                     TRIM49DP"
                     /note="hexamer: ATTAAA"
     polyA_site      2146
                     /gene="TRIM49D1"
                     /gene_synonym="TRIM49D; TRIM49D1P; TRIM49D2; TRIM49D2P;
                     TRIM49DP"
                     /note="major polyA site"
ORIGIN      
        1 aggctgtgct gctgcagccg actgtctggc ccctgagcat tacatcccca tactccaggc
       61 ctttattcat caccaaaaca gcatggtact ggtacaaaaa taggcacata gaccagtgga
      121 acagaataga gaacccagaa atgaacccaa atacttaaca accaactgat ctttgacaaa
      181 gcaaacaaaa acataaagtg gggagaggac accctattca acaaatggtg ctgggataat
      241 tggcaagcca catgtaggag aatgaaactg gactttgtgg catagacaaa ctttcttatt
      301 gttattcaat gaaacactca cgtaggacct actgggaagg tattttgcag atgtaacgaa
      361 aggtcctgct cttgtaacta gcaagtgtac tcagaggtgg gtgtggcctt cacagattct
      421 tataaaagga catagaagag acaagctcag ttttctccaa aggagaagga gcgcacttag
      481 aggaagctgt gttttggtga cctctgaaac tcagtactgc ggcgaatgag ctcctgacct
      541 tgaggagtac ttaacagaat tatttctcga agaatcattg tgggaaccct tcaaagaacc
      601 cagcgaaaca tgaattctgg aatctcgcaa gtcttccaga gggaactcac ctgccccatc
      661 tgcctgaact acttcataga cccggtcacc atagactgtg ggcacagctt ttgcaggccc
      721 tgtttctacc tcaactggca agacatccca attcttactc agtgctttga atgcctaaag
      781 acaacacagc agagaaacct caaaactaac attcgattga agaagatggc ttcccgtgcc
      841 agaaaagcca gtctctggct attcctgagc tctgaggagc aaatgtgtgg cactcacagg
      901 gagacaaaga agatattctg tgaagtggac aggagcctgc tctgtttgct gtgctccagc
      961 tctctggagc accggtatca cagacactgt cccgctgagt gggctgctga ggaacaccgg
     1021 gagaagcttt taaagaaaat gcagtcttta tgggaaaaag tttgtgaaaa tcagagaaac
     1081 ctgaacgtgg aaaccaccag aatcagccac tggaaggatt atgtgaatgt aaggctagaa
     1141 gctattagag ctgagtatca gaagatgcct gcatttcatc atgaagaaga aaaacataat
     1201 ttggagatgc tgaaaaagaa ggggaaagat atttttcatc gacttcattt aagtaaagcc
     1261 aaaatggctc acaggaggga gattttaaga ggaacgtatg cggagctgat gaaaatgtgc
     1321 cataaaccag atgtggagct acttcaggct tttggagaca tattacacag gagtgagtcc
     1381 gtgctgctgc acatgcccca gcctctgaat ctagagctca gggcagggcc catcactgga
     1441 ctgagggaca ggctcaacca attccgagtg gatattactc tgcctcataa tgaagccaac
     1501 agtcatatct tccgacgtgg agatttgaga agcatttgta ttggatgtga ccgtcaaaat
     1561 gcgccccata tcactgcaac acctacaagt tttcttgcat ggggtgctca gactttcacc
     1621 tctggcaaat attactggga ggtccatgtg ggggactctt ggaattgggc ctttggtgtc
     1681 tgtaataagt attggaaagg gacgaatcag aatggcaata tacatggaga ggagggactc
     1741 tttagtcttg ggtgtgttaa gaatgacatt cagtgcagcc tctttaccac ctccccactt
     1801 acactgcagt atgtcccaag acctaccaac catgtaggat tattcctgga ttgtgaagct
     1861 agaactgtga gcttcgttga tgttaatcaa agctccccta tacacaccat ccctaattgc
     1921 tccttctcac ctcctctcag gcctatcttt tgctgtgttc acctctgacc agagacaaat
     1981 cagatatgtg ttcatctgct gtgggaaccc ctttatccca gaaagccctc ttccttgtgc
     2041 cttatcaaac aggacaaata cgttctgttt tatgtcttga attgcattct aatgttatta
     2101 aaactcattt attgtgttac tattaaatgt ggtaaaaaca ctaaaa
//
