LOCUS       NM_001206626            1694 bp    mRNA    linear   PRI 09-JUN-2024
DEFINITION  Homo sapiens tripartite motif containing 49B (TRIM49B), mRNA.
ACCESSION   NM_001206626 XM_208043
VERSION     NM_001206626.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1694)
  AUTHORS   Han,K., Lou,D.I. and Sawyer,S.L.
  TITLE     Identification of a genomic reservoir for new TRIM genes in primate
            genomes
  JOURNAL   PLoS Genet 7 (12), e1002388 (2011)
   PUBMED   22144910
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC084851.2.
            
            On Jul 1, 2020 this sequence version replaced NM_001206626.1.
            
            Sequence Note:.
            
            ##Evidence-Data-START##
            CDS exon combination :: BQ070358.1 [ECO:0000331]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000332682.9/ ENSP00000330216.7
            RefSeq Select criteria    :: based on single protein-coding
                                         transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-153               AC084851.2         12677-12829
            154-568             AC084851.2         15450-15864
            569-664             AC084851.2         16130-16225
            665-895             AC084851.2         18000-18230
            896-918             AC084851.2         18949-18971
            919-1016            AC084851.2         20155-20252
            1017-1694           AC084851.2         21332-22009
FEATURES             Location/Qualifiers
     source          1..1694
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p11.12"
     gene            1..1694
                     /gene="TRIM49B"
                     /note="tripartite motif containing 49B"
                     /db_xref="GeneID:283116"
                     /db_xref="HGNC:HGNC:42955"
     exon            1..153
                     /gene="TRIM49B"
                     /inference="alignment:Splign:2.1.0"
     exon            154..568
                     /gene="TRIM49B"
                     /inference="alignment:Splign:2.1.0"
     CDS             158..1516
                     /gene="TRIM49B"
                     /note="RING finger protein 18B; tripartite
                     motif-containing protein"
                     /codon_start=1
                     /product="putative tripartite motif-containing protein
                     49B"
                     /protein_id="NP_001193555.1"
                     /db_xref="CCDS:CCDS55762.1"
                     /db_xref="GeneID:283116"
                     /db_xref="HGNC:HGNC:42955"
                     /translation="MNSGILQVFQRELICPICMNYFIDPVTIDCGHSFCRPCFYLNWK
                     DSPFLVQCSECTKSTGQINLKTNIHFKKMASLARKVSLWLFLSSEEQMCGTHRETKKM
                     FCEVDRSLLCLLCSSSQEHRDHRHCPIESAAEEHQEKLLQKMQSLWEKACENHRNLNV
                     ETTRTRCWKDYVNLRLEAIRAEYQKMPAFHHEEEKHNLEMLKKKGKDIFHRLHLSKAK
                     MAHRREILRGMYEELNEMCHKPDVELLQAFGDILHRSESVLLHMPQPLNPELSAGPIT
                     GLRDRLNQFRVHITLHHEEANSDIFLCEILRSMCIGCDHQDVPYFTATPRSFLAWGAQ
                     TFTSGKYYWEVHVGDSWNWAFGVCNMYWKEKNQNEKIDGEDGLFLLGCVKNDIQRSLF
                     TTSPLLLQYIPRPTSRVGLFLDCEAKTVSFVDVNQSSLIYTIPNCSFSPPLRPIFCCI
                     HF"
     exon            569..664
                     /gene="TRIM49B"
                     /inference="alignment:Splign:2.1.0"
     exon            665..895
                     /gene="TRIM49B"
                     /inference="alignment:Splign:2.1.0"
     exon            896..918
                     /gene="TRIM49B"
                     /inference="alignment:Splign:2.1.0"
     exon            919..1016
                     /gene="TRIM49B"
                     /inference="alignment:Splign:2.1.0"
     exon            1017..1694
                     /gene="TRIM49B"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1670..1675
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TRIM49B"
                     /note="hexamer: ATTAAA"
     polyA_site      1694
                     /gene="TRIM49B"
                     /note="major polyA site"
ORIGIN      
        1 agttttctct gaaggagaag gactgcactt agaactgcat tttggtgacc tctgaaattc
       61 agtacggcag tgaatgagct tctgacgttg aggtgaactt aacaaaatta tttttggaaa
      121 aatcgttgtg ggaaccatta aaagaactca gggaaacatg aattctggaa tcttacaggt
      181 ctttcagagg gaactcatct gccccatctg catgaactac ttcatagacc cggtcaccat
      241 agactgtggg cacagctttt gcaggccttg tttctacctc aactggaaag acagcccatt
      301 tcttgtccag tgctctgaat gcacaaagtc aacagggcag ataaacctca aaaccaacat
      361 tcatttcaag aagatggctt ctcttgctag aaaagtcagt ctctggctat tcctgagctc
      421 tgaggagcaa atgtgtggca ctcacaggga gacaaagaag atgttctgtg aagtggacag
      481 gagcctgctc tgtttgctgt gctccagctc tcaggagcac cgggatcaca gacactgtcc
      541 cattgagtcg gctgctgagg aacaccagga gaagctttta cagaaaatgc agtctttgtg
      601 ggaaaaagct tgtgaaaatc acagaaacct gaatgtggaa accaccagaa ccagatgctg
      661 gaaggattat gtgaatttaa ggctagaagc aattagagct gagtatcaga agatgcctgc
      721 atttcaccat gaagaagaaa aacataattt ggagatgctg aaaaagaagg ggaaagatat
      781 ttttcatcga cttcatttaa gtaaagccaa aatggctcat aggagggaga ttttaagagg
      841 aatgtatgag gagctgaacg aaatgtgcca taaaccagat gtggagctac ttcaggcttt
      901 tggagacata ttacacagga gtgagtccgt gctgctgcac atgccccagc ctctgaatcc
      961 agagctcagt gcagggccca tcactggact gagggacagg ctcaaccaat tccgagtgca
     1021 tattactctg catcatgaag aagccaacag tgatatcttt ctatgtgaaa ttttgagaag
     1081 catgtgtatt ggatgtgacc atcaagatgt accctatttc actgcaacac ctagaagttt
     1141 tcttgcatgg ggtgctcaga ctttcacctc gggcaaatat tactgggagg tccatgtagg
     1201 ggactcctgg aattgggctt ttggtgtctg taatatgtat tggaaagaga agaatcagaa
     1261 tgagaagata gatggagagg atggactctt tcttcttggg tgtgttaaga atgacattca
     1321 acgcagtctc tttaccacct ccccacttct gctgcaatat atcccaagac ctaccagccg
     1381 agtaggatta ttcctggatt gtgaggctaa gactgtgagc tttgttgatg ttaatcaaag
     1441 ctccctaata tacaccatcc ctaattgctc tttctcacct cctctcaggc ctatcttttg
     1501 ctgtattcac ttctgaccag agacaaatca gaaatgtgtt cacatgctgt gggaacccct
     1561 ttatcccagg aagtcctctt ccttgtgcct taacatacag gacaaatagg ctctatttta
     1621 tatcttgaat tgccttctaa tgttatcaaa actcatttat tgtgttacta ttaaatatgc
     1681 tgaaaacact aaaa
//
