LOCUS       NM_213590               7255 bp    mRNA    linear   PRI 11-JUN-2024
DEFINITION  Homo sapiens tripartite motif containing 13 (TRIM13), transcript
            variant 3, mRNA.
ACCESSION   NM_213590
VERSION     NM_213590.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7255)
  AUTHORS   Govatati,S., Kumar,R., Boro,M., Traylor,J.G. Jr., Orr,A.W.,
            Lusis,A.J. and Rao,G.N.
  TITLE     TRIM13 reduces cholesterol efflux and increases oxidized LDL uptake
            leading to foam cell formation and atherosclerosis
  JOURNAL   J Biol Chem 300 (5), 107224 (2024)
   PUBMED   38537695
  REMARK    GeneRIF: TRIM13 reduces cholesterol efflux and increases oxidized
            LDL uptake leading to foam cell formation and atherosclerosis.
REFERENCE   2  (bases 1 to 7255)
  AUTHORS   Yu,B., Zhou,Y. and He,J.
  TITLE     TRIM13 inhibits cell proliferation and induces autophagy in lung
            adenocarcinoma by regulating KEAP1/NRF2 pathway
  JOURNAL   Cell Cycle 22 (12), 1496-1513 (2023)
   PUBMED   37245083
  REMARK    GeneRIF: TRIM13 inhibits cell proliferation and induces autophagy
            in lung adenocarcinoma by regulating KEAP1/NRF2 pathway.
REFERENCE   3  (bases 1 to 7255)
  AUTHORS   Roshanazadeh,M.R., Adelipour,M., Sanaei,A., Chenane,H. and
            Rashidi,M.
  TITLE     TRIM3 and TRIM16 as potential tumor suppressors in breast cancer
            patients
  JOURNAL   BMC Res Notes 15 (1), 312 (2022)
   PUBMED   36180926
  REMARK    GeneRIF: TRIM3 and TRIM16 as potential tumor suppressors in breast
            cancer patients.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 7255)
  AUTHORS   Li,Y., Ren,D., Shen,Y., Zheng,X. and Xu,G.
  TITLE     Altered DNA methylation of TRIM13 in diabetic nephropathy
            suppresses mesangial collagen synthesis by promoting ubiquitination
            of CHOP
  JOURNAL   EBioMedicine 51, 102582 (2020)
   PUBMED   31901873
  REMARK    GeneRIF: Altered DNA methylation of TRIM13 in diabetic nephropathy
            suppresses mesangial collagen synthesis by promoting ubiquitination
            of CHOP.
REFERENCE   5  (bases 1 to 7255)
  AUTHORS   Xu,L., Wu,Q., Zhou,X., Wu,Q. and Fang,M.
  TITLE     TRIM13 inhibited cell proliferation and induced cell apoptosis by
            regulating NF-kappaB pathway in non-small-cell lung carcinoma cells
  JOURNAL   Gene 715, 144015 (2019)
   PUBMED   31357025
  REMARK    GeneRIF: results indicate that TRIM13 behaves as a tumor suppressor
            in non-small-cell lung carcinoma through regulating NF-kappaB
            pathway.
REFERENCE   6  (bases 1 to 7255)
  AUTHORS   van Everdink,W.J., Baranova,A., Lummen,C., Tyazhelova,T.,
            Looman,M.W., Ivanov,D., Verlind,E., Pestova,A., Faber,H., van der
            Veen,A.Y., Yankovsky,N., Vellenga,E. and Buys,C.H.
  TITLE     RFP2, c13ORF1, and FAM10A4 are the most likely tumor suppressor
            gene candidates for B-cell chronic lymphocytic leukemia
  JOURNAL   Cancer Genet Cytogenet 146 (1), 48-57 (2003)
   PUBMED   14499696
REFERENCE   7  (bases 1 to 7255)
  AUTHORS   Reymond,A., Meroni,G., Fantozzi,A., Merla,G., Cairo,S., Luzi,L.,
            Riganelli,D., Zanaria,E., Messali,S., Cainarca,S., Guffanti,A.,
            Minucci,S., Pelicci,P.G. and Ballabio,A.
  TITLE     The tripartite motif family identifies cell compartments
  JOURNAL   EMBO J 20 (9), 2140-2151 (2001)
   PUBMED   11331580
REFERENCE   8  (bases 1 to 7255)
  AUTHORS   Migliazza,A., Bosch,F., Komatsu,H., Cayanis,E., Martinotti,S.,
            Toniato,E., Guccione,E., Qu,X., Chien,M., Murty,V.V., Gaidano,G.,
            Inghirami,G., Zhang,P., Fischer,S., Kalachikov,S.M., Russo,J.,
            Edelman,I., Efstratiadis,A. and Dalla-Favera,R.
  TITLE     Nucleotide sequence, transcription map, and mutation analysis of
            the 13q14 chromosomal region deleted in B-cell chronic lymphocytic
            leukemia
  JOURNAL   Blood 97 (7), 2098-2104 (2001)
   PUBMED   11264177
REFERENCE   9  (bases 1 to 7255)
  AUTHORS   Kapanadze,B., Makeeva,N., Corcoran,M., Jareborg,N., Hammarsund,M.,
            Baranova,A., Zabarovsky,E., Vorontsova,O., Merup,M., Gahrton,G.,
            Jansson,M., Yankovsky,N., Einhorn,S., Oscier,D., Grander,D. and
            Sangfelt,O.
  TITLE     Comparative sequence analysis of a region on human chromosome
            13q14, frequently deleted in B-cell chronic lymphocytic leukemia,
            and its homologous region on mouse chromosome 14
  JOURNAL   Genomics 70 (3), 327-334 (2000)
   PUBMED   11161783
REFERENCE   10 (bases 1 to 7255)
  AUTHORS   Kapanadze,B., Kashuba,V., Baranova,A., Rasool,O., van Everdink,W.,
            Liu,Y., Syomov,A., Corcoran,M., Poltaraus,A., Brodyansky,V.,
            Syomova,N., Kazakov,A., Ibbotson,R., van den Berg,A.,
            Gizatullin,R., Fedorova,L., Sulimova,G., Zelenin,A., Deaven,L.,
            Lehrach,H., Grander,D., Buys,C., Oscier,D., Zabarovsky,E.R.,
            Einhorn,S. and Yankovsky,N.
  TITLE     A cosmid and cDNA fine physical map of a human chromosome 13q14
            region frequently lost in B-cell chronic lymphocytic leukemia and
            identification of a new putative tumor suppressor gene, Leu5
  JOURNAL   FEBS Lett 426 (2), 266-270 (1998)
   PUBMED   9599022
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AY455758.1, KF455768.1 and
            AL832695.1.
            
            On Nov 22, 2018 this sequence version replaced NM_213590.2.
            
            Summary: This gene encodes a member of the tripartite motif (TRIM)
            family. The TRIM motif includes three zinc-binding domains, a RING,
            a B-box type 1 and a B-box type 2, and a coiled-coil region. This
            gene is located on chromosome 13 within the minimal deletion region
            for B-cell chronic lymphocytic leukemia. Multiple alternatively
            spliced transcript variants have been found for this gene.
            [provided by RefSeq, Jul 2008].
            
            Transcript Variant: This variant (3) differs in the 5' UTR compared
            to variant 1. Variants 1, 2 and 3 encode the same protein (isoform
            1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY455758.1, SRR1803612.133511.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000378182.4/ ENSP00000367424.3
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-6131              AY455758.1         11-6141
            6132-6132           KF455768.1         197-197
            6133-7239           AY455758.1         6143-7249
            7240-7255           AL832695.1         2964-2979
FEATURES             Location/Qualifiers
     source          1..7255
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="13"
                     /map="13q14.2"
     gene            1..7255
                     /gene="TRIM13"
                     /gene_synonym="CAR; DLEU5; LEU5; RFP2; RNF77"
                     /note="tripartite motif containing 13"
                     /db_xref="GeneID:10206"
                     /db_xref="HGNC:HGNC:9976"
                     /db_xref="MIM:605661"
     exon            1..722
                     /gene="TRIM13"
                     /gene_synonym="CAR; DLEU5; LEU5; RFP2; RNF77"
                     /inference="alignment:Splign:2.1.0"
     exon            723..7255
                     /gene="TRIM13"
                     /gene_synonym="CAR; DLEU5; LEU5; RFP2; RNF77"
                     /inference="alignment:Splign:2.1.0"
     CDS             729..1952
                     /gene="TRIM13"
                     /gene_synonym="CAR; DLEU5; LEU5; RFP2; RNF77"
                     /EC_number="2.3.2.27"
                     /note="isoform 1 is encoded by transcript variant 3; ret
                     finger protein 2; tripartite motif protein 13;
                     CLL-associated RING finger; tripartite motif-containing
                     protein 13; E3 ubiquitin-protein ligase TRIM13; RING
                     finger protein 77; leukemia-associated protein 5; putative
                     tumor suppressor RFP2; B-cell chronic lymphocytic leukemia
                     tumor suppressor Leu5; RING-type E3 ubiquitin transferase
                     TRIM13"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase TRIM13 isoform 1"
                     /protein_id="NP_998755.1"
                     /db_xref="CCDS:CCDS9423.1"
                     /db_xref="GeneID:10206"
                     /db_xref="HGNC:HGNC:9976"
                     /db_xref="MIM:605661"
                     /translation="MELLEEDLTCPICCSLFDDPRVLPCSHNFCKKCLEGILEGSVRN
                     SLWRPAPFKCPTCRKETSATGINSLQVNYSLKGIVEKYNKIKISPKMPVCKGHLGQPL
                     NIFCLTDMQLICGICATRGEHTKHVFCSIEDAYAQERDAFESLFQSFETWRRGDALSR
                     LDTLETSKRKSLQLLTKDSDKVKEFFEKLQHTLDQKKNEILSDFETMKLAVMQAYDPE
                     INKLNTILQEQRMAFNIAEAFKDVSEPIVFLQQMQEFREKIKVIKETPLPPSNLPASP
                     LMKNFDTSQWEDIKLVDVDKLSLPQDTGTFISKIPWSFYKLFLLILLLGLVIVFGPTM
                     FLEWSLFDDLATWKGCLSNFSSYLTKTADFIEQSVFYWEQVTDGFFIFNERFKNFTLV
                     VLNNVAEFVCKYKLL"
     regulatory      1938..1943
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TRIM13"
                     /gene_synonym="CAR; DLEU5; LEU5; RFP2; RNF77"
                     /note="hexamer: TATAAA"
     polyA_site      1958
                     /gene="TRIM13"
                     /gene_synonym="CAR; DLEU5; LEU5; RFP2; RNF77"
                     /note="major polyA site"
     regulatory      7234..7239
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TRIM13"
                     /gene_synonym="CAR; DLEU5; LEU5; RFP2; RNF77"
                     /note="hexamer: AATAAA"
     polyA_site      7255
                     /gene="TRIM13"
                     /gene_synonym="CAR; DLEU5; LEU5; RFP2; RNF77"
ORIGIN      
        1 gagtccattt tggggctgtg cttggcgcgt accgtgcggt ccctgtagtt ggaggacggg
       61 cggtcgcgcg gcctttccca ctagccggag gtcggagata agtacccgcc gcccggctcc
      121 tctcgggaaa gcggggtggt cctcgaacct tcagcgaggg tggggagttg cccaggtcag
      181 cagggatctg cgtgggttgg gggggctggc gaaggccgtc tgagctccag tccggcagcg
      241 cggcagaaac cagcggggca ctgtcatggg cctggggagg agcggcctgc ggagggcgcc
      301 ggggcagtgt gtctgtggtc cagaaaacct gctccgtccg gagccttcct ggccccgcta
      361 ccagcgtctc cacatcccct agaaaagaaa agacgggtgt gggccttagg ttacagcgcg
      421 ccgccagcgt ttggttgcat ggcgccgggg gagggcgccc taaccgagaa gctgcttaat
      481 acaaagagct ccaggctcct ggcggttcac caggtctaaa cagccgggct ttatttgtgg
      541 gggcgattga aaaaattgag ggtcaagatt ggggtgctgt gcaaataaat gcgttaatac
      601 tgttcttttt cttctttctt tgcagtagcc tctagttcgt tagtcaaaac gtgaaaaaaa
      661 agacctgctt tgccctggga aatagtaacc ctgccaaata catcagcttg taggagacag
      721 aggatgtgat ggagctgctt gaagaagatc tcacatgccc tatttgttgt agtctgtttg
      781 atgatccacg ggttttgcct tgctcccaca acttctgcaa aaaatgctta gaaggtatct
      841 tagaagggag tgtgcggaat tccttgtgga gaccagctcc attcaagtgt cctacatgcc
      901 gtaaggaaac ttcagctact ggaattaata gcctgcaggt taattactcc ctgaagggta
      961 ttgtggaaaa gtataacaag atcaagatct ctcccaaaat gccagtatgc aaaggacact
     1021 tggggcagcc tctcaacatt ttctgcctga ctgatatgca gctgatttgt gggatctgtg
     1081 ctactcgtgg ggagcacacc aaacatgtct tctgttctat tgaagatgcc tatgctcagg
     1141 aaagggatgc ctttgagtcc ctcttccaga gctttgagac ctggcgtcgg ggagatgctc
     1201 tttctcgctt ggataccttg gaaactagta agaggaaatc cctacagtta ctgactaaag
     1261 attcagataa agtgaaggaa ttttttgaga agttacaaca cacactggat caaaagaaga
     1321 atgaaattct gtctgacttt gagaccatga aacttgctgt tatgcaagca tatgacccag
     1381 agatcaacaa actcaacacc atcttgcagg agcaacggat ggcctttaac attgctgagg
     1441 ctttcaaaga tgtgtcagaa cccattgtat ttctgcaaca gatgcaggag tttagagaga
     1501 aaatcaaagt aatcaaggaa actcctttac ctccctctaa tttgcctgca agccctttaa
     1561 tgaagaactt tgataccagt cagtgggaag acataaaact agtcgatgtg gataaacttt
     1621 ctttgcctca agacactggc acattcatta gcaagattcc ctggagcttt tataagttat
     1681 ttttgctaat ccttctgctt ggccttgtca ttgtctttgg tcctaccatg ttcctagaat
     1741 ggtcattatt tgatgacctg gcaacttgga aaggctgtct ttcaaacttc agttcctatc
     1801 tgactaaaac agccgatttc atagaacaat cagtttttta ctgggaacag gtgacagatg
     1861 ggtttttcat tttcaatgaa agattcaaga attttacttt ggtggtactg aacaatgtgg
     1921 cagaatttgt gtgcaaatat aaactattat aaaatctgtt tcaagtatgc agttttcttt
     1981 tgttagaaat tgttagagaa tagagagtgg taattcagat ttggtcaacg attctagtca
     2041 catattttcc tccaaaagta ttccttccaa aaataatcta tacatgttca aattaggtag
     2101 cataaagata aaagtgaaat ttagtagtat aggcctgaac ctttttttgt ttaaaagagt
     2161 gcttttgaaa taagcatcca ccccaaatgt tggttgtatt tatgctgtga taaaaatagg
     2221 tgagagatca tatgatctaa tattgtattg atggaagtat aggtagtata gtagtgattg
     2281 ttcttcaagc atgcagtaaa gatcactttt tttttttttt ttttttttga gatggagtct
     2341 tgctctgtcg cccaggctgg agtgcagtga tgcaatcttg gctcactgca gcctctacct
     2401 cccaggttca agtgattatc ctgccttagc ctcctgagta gctgggatta caggcgcgtg
     2461 ccaccacgcc cagctaattt tttgtatttt tagttgagac agggtttcac tgtcccttaa
     2521 gaccatcctg ttagccaaga tggtcttgat ctcctgacct cgtgatccgc ctgcctcggc
     2581 ctcccaaagt gctgggatta caggtgtgag ccaccgtgcc cagccaaaga ctgctcttaa
     2641 agcacctttt tgacagtgaa catggtctaa aaaagggaag atattgtaga agatttcaca
     2701 cacacacgcg tgtgtgggag acaactaaag gtattgaagg tactaattaa ttagatttcc
     2761 aaaattttct acagagagtt aattatcacc aaaatgtgaa tggtacatac aaaacctggc
     2821 attttcttgt gataagttta catttttagg agagtggagc tttcaatctg cccttttctc
     2881 ctttgttttt gtagttttca ccaaagatga tcaactagaa atgttaagtg gctatgcaag
     2941 caaaagcata gataggttaa aaaaaaggat cagctggctg ggcagggtgg ctcatgtcta
     3001 taatctcagc attctaggac agtgatgtgg gaggattatt tgaggctagg agttccagtt
     3061 cgaaaccagc ttcgtaaaca tagcaagacc cagtctctac caaaaaaaaa aaaaaaaaaa
     3121 aaaaaaaaaa aaatatatat atatatatac acacacacac acacatatgt acacatacat
     3181 atatatacat atatatgtat atatagaaca catggcaaga gcaggaaatg ggaagactac
     3241 cttttttctg gcagctatgt gttgttttgt tcgaaagatg gcaagtgtac aaccaaacca
     3301 atccacttgc ttacagaaag aatgtttagt gtagttaaga ctaatttgac aacagataaa
     3361 acagtctgtc agctattaca aagtaatcag ctgaacacta atgctgttct gtctgctcac
     3421 aagagataaa gataccctct catggaataa acaccttgct tagaattcat ataacaaaga
     3481 agtaacctta taactgctct ctagtctgcc ttatttgtgt catagagtaa gatattcctt
     3541 gaaagcccat taagtggaat agactttctg aaaataagag ttctttacct cagtcctcct
     3601 ctaatttggt tgagaggagg taatgaaaat ggggacagga taaaaggtgg caactaaatt
     3661 taaagcacag aagaaatgat ttccttctag ctatgagaat agtcaaattg agcttgccag
     3721 gctgtctcat tcctaacatg taattcatga tttagccact aaatttctaa ggagatcata
     3781 agaaattaag aaaaacgttt aagtctagcc tctgcgtggt agacaggtat ggggagggag
     3841 aatgcttttc ccctcccagt aataaaaaaa aaaaaaaaaa aaatatatat atatatatat
     3901 atatatatat atatatatat atatatatat atatatatag ttttactagg ttttcatgga
     3961 taagttttta aatgtaagac aggaaaggga tctatttgat gtctatcttc agatatattg
     4021 gcagttttcc ttaagctatt tagttcctca tctgttgctt tttcattttg tatactgcaa
     4081 gttcccaggc aactcgaatt tgcaaacaca gccatggata cactatttac cttacagtag
     4141 tttcctggga atctaagtct ggtttttgtt attcttccct cccctccact gcataatcat
     4201 gtataactag caacatttat ggttataggt tgatttccta agtgtggctg atggtagcct
     4261 ctagtttgaa gtgagggaag aatgagtagt caggaactgg tcactttgaa tgtgggaggg
     4321 aagatattca cgacaaggtt ttctacgata aagcagtttc ctgcttctcg tttggcacgc
     4381 atgttagatg gcagagacca agaattcaag atggttggtg gccagatttt tgtagacaga
     4441 gatggtgatt tgtttagttt catcttagat tttttgagaa ctcaccagct tttattaccc
     4501 actgaatttt cagactatct taggcttcag agagaggctc ttttctatga acttcgttct
     4561 ctagttgatc tcttaaaccc atacctgcta cagccaagac ctgctcttgt ggaggtacat
     4621 ttcctaagcc ggaacactca agcttttttc agggtgtttg gctcttgcag caaaacaatt
     4681 gagatgctaa cagggaggat tacagtgttt acagaacaac cttcagcgcc gacctggaat
     4741 ggtaactttt tccctcctca gatgacctta cttccactgc ctccacaaag accttcttac
     4801 catgacctgg ttttccagtg tggttctgac agcactactg ataaccaaac tggagtcagg
     4861 tattttgtac tttgcagtat ttctcttgta taccagtttg tgatgttttc tctaaaaact
     4921 tgaagttcct caggcctgta acttctggaa aagatgatta ttcaaaataa tgttttgggg
     4981 taaccagtgg agttgggtag aatgaccaaa taattatttt ccaaactggg atacttttta
     5041 gagtgaaagg ggctattatt aggtgggaca aaaggaataa atgaagactg cccagaaaaa
     5101 actgagacta tggacattca aatcatggga gaaaataatt ttgtagatta tgttccattg
     5161 ctaatgaatt tgacttagaa aagaattgcc ttatttttaa gagattgttt cagtggttca
     5221 cataaaggct cgctcactgg tttctcttga gttccttaca cactatataa gttgttcttt
     5281 cagttttatg attcaactac tgtttttcct tcagctgact ttatttttaa acacccttaa
     5341 agacagatat atctcatggc aaatttggta tcctgttaca gccttggctc ttaaacaact
     5401 caaaatattg ggataggctg tcagtatgtt aaggatagtt gctcctgagt caattcttca
     5461 cttactccct ctgttgttct tggctggatc ctaacgctga tttccactct gctgtcacaa
     5521 acatttttcc ccccgtaaaa tgtcttaatg ctgtcctacc attattttac caactgtgaa
     5581 agctggcttt aatttttagg aggaaaagaa aagcctgcat gtgttcttta ttggtatcat
     5641 ttaaaatata cttttttttt tttttttggt aaaggtaggc gtattttaag atattttctt
     5701 aacttgagca gtagccaaca ggaaggatac cagtgtctct ctctcttagc gacacactcc
     5761 ttggtcttgc ttaccaactg gaggacacta ggtagaataa ccgagtatga caattcttaa
     5821 ttgtttacat tttataactt cctgtccttc aaaagagttt gaaatgtcat tttgggaaaa
     5881 gagagccagt caagctagta ggctgattgt gaagaaaatc taatacctta tctttatctc
     5941 aaacctctgt acaactttat tttcattgat gggatacttt aacaaaaatg aaattttttt
     6001 tggtttttaa aatatgagtg attatgacct ctttggggat catgcttcaa aaagtcagaa
     6061 acctagagac aaaactgtca ttgattttta agaagaaaca cactaggtca aaagaagatg
     6121 tcctggaaat acgaagtact ctttaaaaac catgcatttg gagaaagtaa ttgtttcctt
     6181 gaaaaacatg attaaaaact aaaactggga tgttcctgtg tgtacacagt gccaaatggt
     6241 tttccctttt tatgttgtgt tttagaaaca gcacgaaagt tttttccatt ttaaagtgag
     6301 aaaacattat atttagactt ccataattcc aaaatcagaa gctattttta aaattagcat
     6361 tttcttgcat caccaaatgg tattcaattg tttgaagctc aaaattttta ccattccata
     6421 aatgtttgtg aatttttaga cagtgccaat ttaaaagtag agatagccaa tctgaatacg
     6481 gtgaaattat ggggatctct ggtgattggg atgaaaactc tggccttaaa aggtccactt
     6541 ttagtatata attgcctaat tagcaatcat ttttattttt tgctcactcc ctggtctgaa
     6601 tctatctgtc tattcagata ttttttggta ggtttggaaa atggagaagt gagcctaatt
     6661 ggtgcctaat tgtctggtgt atcattcact ttattcagtt tgttctatca atatgattta
     6721 cccctcaagg ttaacctagc aggttgctca gttattatct ctcaaggtca cagtactaga
     6781 aatacttggc ttgcatcttt cagatgccat tcatgttatc aagctcaaat tatagttggt
     6841 cacaggattc taaagtcttt atttgacttc tcctttttga actggctcaa atggaaaagt
     6901 gtagttgctt ttaaatgtta aaaataagtt taaactttat atttcccatt ggtttcccct
     6961 attttgtcct ttctttgtgt gcttgaaata ttttattttt cagtttgtcc tcatagggaa
     7021 tcaagtattt tagctaggtg atgtcttgca agtacgttcc actttgttac aatctactat
     7081 ctgtatatac tatttgtatc ttaattcttt tatgagatgt tctgtaacat ttttctcact
     7141 ttgacaaatg tttttagact gtacagtcaa gatctggcgc ttgggggtaa gtggaatgat
     7201 ttgctaatat tgagaatctg ttgtatcaaa cataataaac tttttttgag atgtg
//
