LOCUS       XM_047430579            3643 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens tripeptidyl peptidase 2 (TPP2), transcript
            variant X3, mRNA.
ACCESSION   XM_047430579
VERSION     XM_047430579.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000013.11) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3643
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="13"
     gene            1..3643
                     /gene="TPP2"
                     /gene_synonym="IMD78; TPP-2; TPP-II; TPPII"
                     /note="tripeptidyl peptidase 2; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 105
                     ESTs, 786 long SRA reads, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     149 samples with support for all annotated introns"
                     /db_xref="GeneID:7174"
                     /db_xref="HGNC:HGNC:12016"
                     /db_xref="MIM:190470"
     CDS             54..3467
                     /gene="TPP2"
                     /gene_synonym="IMD78; TPP-2; TPP-II; TPPII"
                     /codon_start=1
                     /product="tripeptidyl-peptidase 2 isoform X3"
                     /protein_id="XP_047286535.1"
                     /db_xref="GeneID:7174"
                     /db_xref="HGNC:HGNC:12016"
                     /db_xref="MIM:190470"
                     /translation="MATAATEEPFPFHGLLPKKETGAASFLCRYPEYDGRGVLIAVLD
                     TGVDPGAPGMQVTTDGKPKIVDIIDTTGSGDVNTATEVEPKDGEIVGLSGRVLKIPAS
                     WTNPSGKYHIGIKNGYDFYPKALKERIQKERKEKIWDPVHRVALAEACRKQEEFDVAN
                     NGSSQANKLIKEELQSQVELLNSFEKKYSDPGPVYDCLVWHDGEVWRACIDSNEDGDL
                     SKSTVLRNYKEAQEYGSFGTAEMLNYSVNIYDDGNLLSIVTSGGAHGTHVASIAAGHF
                     PEEPERNGVAPGAQILSIKIGDTRLSTMETGTGLIRAMIEVINHKCDLVNYSYGEATH
                     WPNSGRICEVINEAVWKHNIIYVSSAGNNGPCLSTVGCPGGTTSSVIGVGAYVSPDMM
                     VAEYSLREKLPANQYTWSSRGPSADGALGVSISAPGGAIASVPNWTLRGTQLMNGTSM
                     SSPNACGGIALILSGLKANNIDYTVHSVRRALENTAVKADNIEVFAQGHGIIQVDKAY
                     DYLVQNTSFANKLGFTVTVGNNRGIYLRDPVQVAAPSDHGVGIEPVFPENTENSEKIS
                     LQLHLALTSNSSWVQCPSHLELMNQCRHINIRVDPRGLREGLHYTEVCGYDIASPNAG
                     PLFRVPITAVIAAKVNESSHYDLAFTDVHFKPGQIRRHFIEVPEGATWAEVTVCSCSS
                     EVSAKFVLHAVQLVKQRAYRSHEFYKFCSLPEKGTLTEAFPVLGGKAIEFCIARWWAS
                     LSDVNIDYTISFHGIVCTAPQLNIHASEGINRFDVQSSLKYEDLAPCITLKNWVQTLR
                     PVSAKTKPLGSRDVLPNNRQLYEMVLTYNFHQPKSGEVTPSCPLLCELLYESEFDSQL
                     WIIFDQNKRQMGSGDAYPHQYSLKLEKGDYTIRLQIRHEQISDLERLKDLPFIVSHRL
                     SNTLSLDIHENHSFALLGKKKSSNLTLPPKYNQPFFVTSLPDDKIPKGAGPGCYLAGS
                     LTLSKTELGKKAGQSAAKRQGKFKKDVIPVHYYLIPPPTKTKNGSKDKEKDSEKEKDL
                     KEEFTEALRDLKIQWMTKLDSSDIYNELKETYPNYLPLYVARLHQLDAEKERMKRLNE
                     IVDAANAVISHIDQTALAVYIAMKTDPRPDAATIKKYLTMTWTNKNPPS"
ORIGIN      
        1 agtccgcgcg cagcctggca gtttgccgct tcctcgtcct ccatcctgcg tccatggcca
       61 ccgctgcgac tgaggagccc ttcccttttc acggtctcct gccgaagaag gagaccggag
      121 ccgcctcctt cctctgccgc tacccggagt atgatgggcg gggggtgctc atcgcagtcc
      181 tggacacggg ggtcgacccg ggggctccgg gcatgcaggt tacaactgat ggaaaaccaa
      241 aaatcgttga tatcattgat acaacaggaa gtggcgatgt gaatactgct acagaagtag
      301 agccaaagga tggtgagatt gttggccttt caggaagagt gcttaagatt cctgcaagct
      361 ggacaaatcc ctcaggcaaa tatcatattg gcataaaaaa tggctatgac ttctatccta
      421 aggcactcaa ggaaaggata cagaaagaac ggaaggaaaa aatctgggac cctgttcaca
      481 gagtggccct tgcagaagcc tgtagaaaac aggaagaatt tgatgttgcc aacaacggct
      541 cttctcaagc aaataaacta atcaaggagg aacttcaaag tcaagtggaa ttgctaaatt
      601 cttttgagaa gaaatacagc gatcctggcc ctgtatatga ctgcttggta tggcatgatg
      661 gcgaagtctg gagagcctgc attgattcta atgaagatgg ggacttgagt aaatctaccg
      721 tgttgagaaa ctacaaagaa gcccaagaat atggctcttt tggcacagct gagatgttga
      781 attactccgt taatatatac gatgatggaa acctgctctc cattgtgacc agtggaggag
      841 ctcatgggac acatgtagct agtatagctg ctggacactt tccagaagaa cctgaacgga
      901 atggggtagc tcctggtgct caaattcttt ccatcaagat tggtgataca agactaagca
      961 caatggaaac aggcacaggc ctcataagag ctatgataga agttataaat cataagtgtg
     1021 atcttgtcaa ctacagttac ggagaagcaa ctcactggcc aaattctggg agaatttgtg
     1081 aagtaattaa tgaagcagta tggaagcata atataattta tgtttcaagt gctggaaata
     1141 atggtccatg cctgtctaca gttggttgtc caggtggaac tacatcaagt gtgataggtg
     1201 ttggtgctta tgtttctcct gatatgatgg ttgctgagta ttcactgaga gagaaattac
     1261 ctgcaaatca atatacttgg tcttctagag gacctagtgc tgacggggcc cttggtgtga
     1321 gtatcagtgc gccaggagga gccattgctt ctgttcctaa ctggacactg agagggacgc
     1381 agctgatgaa tggaacatct atgtcttccc ccaatgcatg tggaggcatt gccctgatcc
     1441 tttcaggtct gaaagctaat aacattgact acacagttca ttcagtcaga agagctctag
     1501 aaaacactgc agtgaaggct gacaatatag aagtatttgc tcaaggacat ggtattattc
     1561 aggttgataa agcctatgac tacctcgttc agaatacatc atttgctaat aaattaggtt
     1621 ttactgttac tgttggaaat aaccgtggca tctacctccg agatcctgtt caggtggctg
     1681 caccttcaga tcatggcgtt ggcattgaac ctgtatttcc ggagaacaca gaaaactctg
     1741 aaaaaatatc ccttcagctt catttagctc tgacttcaaa ttcatcttgg gttcagtgtc
     1801 ccagccattt ggaactcatg aatcaatgta gacacataaa catacgtgtg gatcccaggg
     1861 gcttaagaga aggattgcat tatacagagg tatgtggcta tgatatagca tcccctaacg
     1921 caggtccgct cttcagagtt ccgatcactg cagttatagc agcaaaagta aatgaatcat
     1981 cacattatga tctagccttt acagatgtac actttaaacc tggtcaaatt cgaaggcatt
     2041 ttattgaggt tcctgagggt gcaacatggg ctgaagtgac agtgtgttcg tgttcttctg
     2101 aggtgtcagc aaagtttgtt ctacatgcag tccagcttgt gaagcaaaga gcatatcgaa
     2161 gccatgaatt ctataagttt tgttctcttc cagagaaagg aacactgact gaagcttttc
     2221 ctgtcctagg tggaaaagca attgaatttt gcattgctcg ttggtgggca agtctcagtg
     2281 atgtcaacat tgattatacc atttctttcc atgggatagt gtgtactgct cctcagttaa
     2341 acattcatgc atcggaagga atcaaccgct ttgatgttca gtcctccttg aaatacgaag
     2401 atctggctcc ctgcataact ttgaagaact gggtccaaac actgcgccca gtgagtgcaa
     2461 aaacaaaacc tttaggatca agagatgttt tgccaaataa ccgtcaactt tatgagatgg
     2521 tcctgacata taactttcat caacccaaga gtggggaagt aactccaagc tgcccactac
     2581 tttgtgaact attatatgaa tctgaatttg acagccaact gtggattatt tttgaccaga
     2641 acaaaagaca gatgggttca ggcgatgcct atccacatca gtattctttg aaactggaga
     2701 aaggagatta tacaattcga ctacagattc gccatgagca aatcagtgat ttggaacgcc
     2761 ttaaagacct tccatttatt gtttctcata gattgtctaa taccttgagc ttagatattc
     2821 atgaaaatca tagttttgca cttctaggga agaagaaatc aagcaatttg acattaccac
     2881 ccaaatataa ccagccattc tttgttactt ccttacctga tgataaaata cctaaagggg
     2941 caggacctgg atgctatctt gcaggatcct taacattgtc aaagactgaa ctaggaaaga
     3001 aagctgggca gtctgcagca aaacgacaag gaaaatttaa aaaggatgta atccctgttc
     3061 attactactt aatacctcca ccaacaaaga ctaagaatgg cagcaaagat aaggaaaaag
     3121 attcagaaaa agagaaagat ttaaaagaag agtttactga agcattacga gatcttaaaa
     3181 ttcagtggat gacaaagctg gattctagtg acatttataa cgaattgaaa gaaacatatc
     3241 ctaattatct tcctctgtac gttgcacgac ttcatcaatt ggatgctgaa aaggaacgaa
     3301 tgaaaagact taatgaaatt gttgatgcgg caaatgctgt tatttctcat atagatcaaa
     3361 cagccctagc agtttatatt gcaatgaaga ctgatcccag gcctgatgca gctactataa
     3421 aaaagtacct aaccatgaca tggacaaaca aaaatccacc ctcgtagatg ccctttgtag
     3481 gaaaggttgt gccctggcag accatcttct tcacacccag gctcaagacg gagccatttc
     3541 cactgatgca gaaggaaagg aggaggaagg agaaagtcct ttggattctc tggcagaaac
     3601 attttgggaa actactaaat ggactgatct ctttgacaat aag
//
