LOCUS       NM_001001874            1504 bp    mRNA    linear   PRI 21-SEP-2024
DEFINITION  Homo sapiens TPD52 like 3 (TPD52L3), transcript variant 2, mRNA.
ACCESSION   NM_001001874
VERSION     NM_001001874.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1504)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   2  (bases 1 to 1504)
  AUTHORS   Divaris,K., Monda,K.L., North,K.E., Olshan,A.F., Lange,E.M.,
            Moss,K., Barros,S.P., Beck,J.D. and Offenbacher,S.
  TITLE     Genome-wide association study of periodontal pathogen colonization
  JOURNAL   J Dent Res 91 (7 Suppl), 21S-28S (2012)
   PUBMED   22699663
REFERENCE   3  (bases 1 to 1504)
  AUTHORS   Cao,Q., Chen,J., Zhu,L., Liu,Y., Zhou,Z., Sha,J., Wang,S. and Li,J.
  TITLE     A testis-specific and testis developmentally regulated tumor
            protein D52 (TPD52)-like protein TPD52L3/hD55 interacts with TPD52
            family proteins
  JOURNAL   Biochem Biophys Res Commun 344 (3), 798-806 (2006)
   PUBMED   16631610
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL133480.9.
            
            On Jun 2, 2019 this sequence version replaced NM_001001874.2.
            
            Summary: This gene encodes a member of the tumor protein D52-like
            family of proteins. These proteins are characterized by an
            N-terminal coiled-coil motif that is used to form homo- and
            heteromeric complexes with other tumor protein D52-like proteins.
            The encoded protein may play a role in spermatogenesis. Alternative
            splicing results in multiple transcript variants. [provided by
            RefSeq, Oct 2009].
            
            Transcript Variant: This variant (2) has an alternate 3' coding
            region and 3' UTR, compared to variant 1. It encodes isoform 2
            which has a shorter and distinct C-terminus, compared to isoform 1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: HM005710.1, SRR5189667.178235.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000314556.4/ ENSP00000318665.3
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-588               AL133480.9         51067-51654
            589-1504            AL133480.9         53668-54583
FEATURES             Location/Qualifiers
     source          1..1504
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9p24.1"
     gene            1..1504
                     /gene="TPD52L3"
                     /gene_synonym="D55; hD55; NYDSP25; TPD55"
                     /note="TPD52 like 3"
                     /db_xref="GeneID:89882"
                     /db_xref="HGNC:HGNC:23382"
                     /db_xref="MIM:617567"
     exon            1..588
                     /gene="TPD52L3"
                     /gene_synonym="D55; hD55; NYDSP25; TPD55"
                     /inference="alignment:Splign:2.1.0"
     CDS             222..632
                     /gene="TPD52L3"
                     /gene_synonym="D55; hD55; NYDSP25; TPD55"
                     /note="isoform 2 is encoded by transcript variant 2; tumor
                     protein D55; testis development protein NYD-SP25; protein
                     kinase NYD-SP25; testis tissue sperm-binding protein Li
                     87P; tumor protein D52 like 3"
                     /codon_start=1
                     /product="tumor protein D55 isoform 2"
                     /protein_id="NP_001001874.2"
                     /db_xref="CCDS:CCDS34984.1"
                     /db_xref="GeneID:89882"
                     /db_xref="HGNC:HGNC:23382"
                     /db_xref="MIM:617567"
                     /translation="MPHARTETSVGTYESHSTSELEDLTEPEQRELKTKLTKLEAEIV
                     TLRHVLAAKERRCGELKRKLGLTALVGLRQNLSKSWLDVQVSNTYVKQKTSAALSTMG
                     TLICRKLGGVKKSATFRSFEGLIFNKYTLNQGRN"
     exon            589..1504
                     /gene="TPD52L3"
                     /gene_synonym="D55; hD55; NYDSP25; TPD55"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1478..1483
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TPD52L3"
                     /gene_synonym="D55; hD55; NYDSP25; TPD55"
                     /note="hexamer: AATAAA"
     polyA_site      1504
                     /gene="TPD52L3"
                     /gene_synonym="D55; hD55; NYDSP25; TPD55"
                     /note="major polyA site"
ORIGIN      
        1 acaggccagg tcgtcaactc aactgtcaag gtgtccattg taccagctgg gccatggatc
       61 cctcccgcct gaaatctgac tccacctgcc aagagtctga gcctgcaggc ctagatttcg
      121 actctgctgg ccaagattat ttctctgcag cccaataatt cgactctttc taccaagaat
      181 tggacctgga ctctcttaac gaagatcttc tttcccagtc catgccacat gccaggacag
      241 agacctctgt gggcacatat gaatcccact cgacttctga actggaggat ctgacagagc
      301 ccgagcaaag agagctcaaa accaaactca ctaaattgga ggctgaaatt gtaaccctac
      361 gccacgtact agcagccaaa gagagacgct gtggggaact caagaggaag ttaggcctca
      421 ccgccttggt agggctgaga cagaatctgt ccaagagctg gcttgatgtt caggtctcca
      481 acacctatgt gaaacagaag acatcagctg ctctgtccac catgggcact ctcatctgca
      541 ggaagcttgg aggcgtgaag aagtcggcca cattcagatc ttttgaagga ttgatcttca
      601 ataaatacac gttaaatcaa ggaaggaatt aacatcatat acttcagaca tcaaatatgg
      661 aatccaagag actatcaaca acatgaactt gttcacaagt tccttctgct tttaaacaaa
      721 aatatcgtgt ttattcaaag ccaatctgag accctactct gtatcaagaa ctgtcccagg
      781 ttctgaaagc atagaattag acatcgtatg tgccctctag aaacacttag actttcaaat
      841 cattataatt caatgagtcc taaaatagag ctgtgtgcca gagataaaag aagtcctgag
      901 gaaggggtgt tcaactctgt cttggtaggt cagtaaagac tttagagaga cagaaagtct
      961 tagaggacta ggagaagttt gccagacaga caagaataga acattccaga caacatgcag
     1021 aggaactgag tcacaaagga atgtataaga atggcatatt ctaggaacta acactgtggc
     1081 tagagaggaa ggggaaatgg tgttacatga gtgagggagg ggaaatggtg ttacgtgagt
     1141 aagaaaaaat aagcaggggg caaaatcata agtagtctta catactacat tagatatcaa
     1201 tatttaagcc tgtaggaaat gggaggcatt gaagcactta agtaaaaaag taactatcaa
     1261 atttttgttt tagattactc tggtcatcag agaaatagat taagtattta agaggtagaa
     1321 tctctcagac ttaggaacca actgcatgag gcggggcttg gggggataaa tttgcaagat
     1381 aataaggatg tagaattgaa aaggcctgat attattgaag ctggagttgc acattcattt
     1441 tgctttggct tttttgtatc agtggtcatg ggcaccaaat aaaatgcttc catgaacatt
     1501 tgga
//
