LOCUS       NM_001195528            2931 bp    mRNA    linear   PRI 08-JUN-2024
DEFINITION  Homo sapiens trophoblast glycoprotein like (TPBGL), mRNA.
ACCESSION   NM_001195528 XM_001717487 XM_497310 XM_940231
VERSION     NM_001195528.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2931)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 2931)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16899-16903 (2002)
   PUBMED   12477932
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AP001972.4, BC007804.2 and N54218.1.
            
            On May 17, 2019 this sequence version replaced NM_001195528.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000562197.3/ ENSP00000474988.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1421              AP001972.4         144184-145604
            1422-2924           BC007804.2         1-1503
            2925-2931           N54218.1           220-226
FEATURES             Location/Qualifiers
     source          1..2931
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q13.4"
     gene            1..2931
                     /gene="TPBGL"
                     /note="trophoblast glycoprotein like"
                     /db_xref="GeneID:100507050"
                     /db_xref="HGNC:HGNC:44159"
     exon            1..2931
                     /gene="TPBGL"
                     /inference="alignment:Splign:2.1.0"
     CDS             277..1425
                     /gene="TPBGL"
                     /codon_start=1
                     /product="trophoblast glycoprotein-like precursor"
                     /protein_id="NP_001182457.1"
                     /db_xref="CCDS:CCDS60895.1"
                     /db_xref="GeneID:100507050"
                     /db_xref="HGNC:HGNC:44159"
                     /translation="MAPRAGQPGLQGLLLVAAALSQPAAPCPFQCYCFGGPKLLLRCA
                     SGAELRQPPRDVPPDARNLTIVGANLTVLRAAAFAGGDGDGDQAAGVRLPLLSALRLT
                     HNHIEVVEDGAFDGLPSLAALDLSHNPLRALGGGAFRGLPALRSLQLNHALVRGGPAL
                     LAALDAALAPLAELRLLGLAGNALSRLPPAALRLARLEQLDVRLNALAGLDPDELRAL
                     ERDGGLPGPRLLLADNPLRCGCAARPLLAWLRNATERVPDSRRLRCAAPRALLDRPLL
                     DLDGARLRCADSGADARGEEAEAAGPELEASYVFFGLVLALIGLIFLMVLYLNRRGIQ
                     RWMRNLREACRDQMEGYHYRYEQDADPRRAPAPAAPAGSRATSPGSGL"
     regulatory      2901..2906
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TPBGL"
                     /note="hexamer: TATAAA"
     polyA_site      2931
                     /gene="TPBGL"
                     /note="major polyA site"
ORIGIN      
        1 actcggctcg gagcccggag cggccgcgga agccggaggc cggcgcgcag ggcgagggca
       61 ccgggggcgg ggggctccgc tccccgtctg acccctcttg cccccggcca gtcagccagt
      121 aagtgcggct cctcagactt tcgagacagc gaacggaccg accgggactg ccagccgctc
      181 cgggtcaagg actcgcccca cccgtgcccc ccaccaggcg ctcccaactc actggtgagc
      241 gcggcggccc gggcgctgga tgcgggggcg gccgcgatgg ccccgcgcgc gggacagccg
      301 gggctccagg ggctgctgct cgtggcggcg gcgctgagcc agcccgcggc accctgcccc
      361 ttccagtgct actgcttcgg cggccccaag ctgctgctgc gctgcgcgtc gggagccgag
      421 ctccgccagc ctccgcggga cgtgccgccc gacgcgcgca acctcaccat cgtaggcgcc
      481 aacctgacgg tgctgcgcgc ggccgccttc gccggcgggg acggggacgg cgaccaggcg
      541 gcgggcgtgc gcctgccgct cctgagcgcg ctgcgcctca cgcacaacca catcgaggtg
      601 gtggaggacg gcgccttcga cgggctgccc agcctggcgg cgctcgacct cagccacaac
      661 ccgctgcgcg ccctgggcgg cggcgccttc cgcgggctgc ccgcgctgcg ctcgctgcag
      721 ctcaaccacg cgctggtgcg cggcggcccc gcgctgctgg ccgcgctgga cgctgcgctg
      781 gcaccgctgg ccgagcttcg cctgctgggc ctagcgggca acgcgctgag ccgtctgccg
      841 ccagccgccc tgcgcctggc gcgcctggag cagctggacg tgcgcctcaa cgcgctggcc
      901 ggcctggacc ccgacgagct gcgcgcgctg gagcgcgatg gcggcctccc cgggccgcgc
      961 ctgctgctcg ccgacaaccc cctgcgctgc ggctgtgccg cacgccccct gctggcctgg
     1021 ctgcgcaacg ccacggagcg cgtgcccgac tcgcggcgcc tgcgctgcgc cgccccgcgg
     1081 gcgctgctag accggccgct actggacctg gacggggcgc ggcttcgctg cgcggacagc
     1141 ggcgccgacg ctcgcggaga ggaggcggag gccgccggcc cggagctgga agcctcctac
     1201 gtgttcttcg ggctggtgct ggcactcatc ggcctcatct tcctcatggt gctctaccta
     1261 aaccgccgcg gcatccagcg ctggatgcgc aacctgcgcg aggcgtgccg ggaccagatg
     1321 gagggctacc actaccgcta cgagcaggac gccgacccgc gccgcgcgcc cgcgcccgcc
     1381 gcgcccgcgg gctcccgcgc cacctccccg ggctcggggc tctgagcggc gcccccgggc
     1441 tcggggcttc ccttgcctgg cccgaagccg tggagatgag acacccgcga gccccgagct
     1501 ctgagacctt cccctgactc ggaggcgcta agccgtaccc tctcgttccc gcctccgaga
     1561 gctcccaccg tcaaagaccc agagatagcc ggtccgaatc cagaaacccc gcctgcccac
     1621 cctagtttcc gaaacctccc tcctgaacca ctgaaagtcc gttccccgtc tcggagctca
     1681 cacagagaat ctgtccttca aggccaaagc tctgagactt gcccccagca ccctgtgctt
     1741 ggagctccga cacccgagac tgcactgacc tccctcgcca gctcggagcc ctcagtcccc
     1801 tccggggctt gagggccctt ccatcccatt ctggactcga agcacagcac ccccatcaga
     1861 atggttttgt ggattttgag ccctttgtcc catcccagag ctcagagccc tccatcctgc
     1921 atggaggccc aaccctgggg ctctgaggat tgggcaccct cccctcatct aagaatatat
     1981 ttcatacccc tgccccccct tcacccaccc ccgcctctgg ctcaggccct tcccttcctc
     2041 ggctcaggca tggggctcag ctcctagtct gtccctccca tcccagggac aagcacagcc
     2101 catctagcct tagtgtggag ccaactctca gcctttccca ccagggcgct gacctcccga
     2161 tactcagtgc tggtccccag tctcagactc tcagctcttc accccgatct gactttcgtc
     2221 ctcctgccca agcctttggc tcttgacccc ccccccatac ccaatgctgg cactcagcac
     2281 ccacccctgc cattcactag tcaaggtcca gtgaggaatc cgtccctggg atgtcctcat
     2341 ccccttttcg tcccaggacg agctcttcag tcctgccgga taggtgcagg tgccatgcac
     2401 ccctagtgca tactggcaga tccttgtagg gaaggagaga gtcttgggtg tgtgaaaggg
     2461 atagtggggc atcgtggcct cagagagggg caggaagtgg ggtctgaagg gctggaagtt
     2521 gctgcccttc gatttctcta tgctctctcc cacccctgtg gctcttcgcc cttggggatt
     2581 ccttgccacc accgctacca ccaccacctc accccgtgta tcttctgaaa gagaagtagg
     2641 tctttcctcc tgcctcaggc acaagccctc ctggttcagg gtcagaagct cagcaccttg
     2701 ccttctccat gatcccaaag cacaattggt gagtggggga gaggaccccc tctccctgac
     2761 tccccaccct ctagatcagg cagaatggct ggcctgtgct gcgtctgcac acaggaagtc
     2821 accttccttt aatatattgg cttgaggcct gcctgccctc cccataccca gaaaatctgg
     2881 atctcccttg agcagttttc tataaagtct gcaataatct cagatactct a
//
