LOCUS       NM_014477               2312 bp    mRNA    linear   PRI 09-FEB-2024
DEFINITION  Homo sapiens TP53 target 5 (TP53TG5), mRNA.
ACCESSION   NM_014477
VERSION     NM_014477.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2312)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   2  (bases 1 to 2312)
  AUTHORS   de Mateo,S., Castillo,J., Estanyol,J.M., Ballesca,J.L. and Oliva,R.
  TITLE     Proteomic characterization of the human sperm nucleus
  JOURNAL   Proteomics 11 (13), 2714-2726 (2011)
   PUBMED   21630459
REFERENCE   3  (bases 1 to 2312)
  AUTHORS   Deloukas,P., Matthews,L.H., Ashurst,J., Burton,J., Gilbert,J.G.,
            Jones,M., Stavrides,G., Almeida,J.P., Babbage,A.K., Bagguley,C.L.,
            Bailey,J., Barlow,K.F., Bates,K.N., Beard,L.M., Beare,D.M.,
            Beasley,O.P., Bird,C.P., Blakey,S.E., Bridgeman,A.M., Brown,A.J.,
            Buck,D., Burrill,W., Butler,A.P., Carder,C., Carter,N.P.,
            Chapman,J.C., Clamp,M., Clark,G., Clark,L.N., Clark,S.Y.,
            Clee,C.M., Clegg,S., Cobley,V.E., Collier,R.E., Connor,R.,
            Corby,N.R., Coulson,A., Coville,G.J., Deadman,R., Dhami,P.,
            Dunn,M., Ellington,A.G., Frankland,J.A., Fraser,A., French,L.,
            Garner,P., Grafham,D.V., Griffiths,C., Griffiths,M.N., Gwilliam,R.,
            Hall,R.E., Hammond,S., Harley,J.L., Heath,P.D., Ho,S., Holden,J.L.,
            Howden,P.J., Huckle,E., Hunt,A.R., Hunt,S.E., Jekosch,K.,
            Johnson,C.M., Johnson,D., Kay,M.P., Kimberley,A.M., King,A.,
            Knights,A., Laird,G.K., Lawlor,S., Lehvaslaiho,M.H., Leversha,M.,
            Lloyd,C., Lloyd,D.M., Lovell,J.D., Marsh,V.L., Martin,S.L.,
            McConnachie,L.J., McLay,K., McMurray,A.A., Milne,S., Mistry,D.,
            Moore,M.J., Mullikin,J.C., Nickerson,T., Oliver,K., Parker,A.,
            Patel,R., Pearce,T.A., Peck,A.I., Phillimore,B.J.,
            Prathalingam,S.R., Plumb,R.W., Ramsay,H., Rice,C.M., Ross,M.T.,
            Scott,C.E., Sehra,H.K., Shownkeen,R., Sims,S., Skuce,C.D.,
            Smith,M.L., Soderlund,C., Steward,C.A., Sulston,J.E., Swann,M.,
            Sycamore,N., Taylor,R., Tee,L., Thomas,D.W., Thorpe,A., Tracey,A.,
            Tromans,A.C., Vaudin,M., Wall,M., Wallis,J.M., Whitehead,S.L.,
            Whittaker,P., Willey,D.L., Williams,L., Williams,S.A., Wilming,L.,
            Wray,P.W., Hubbard,T., Durbin,R.M., Bentley,D.R., Beck,S. and
            Rogers,J.
  TITLE     The DNA sequence and comparative analysis of human chromosome 20
  JOURNAL   Nature 414 (6866), 865-871 (2001)
   PUBMED   11780052
REFERENCE   4  (bases 1 to 2312)
  AUTHORS   Isaka,S., Takei,Y., Tokino,T., Koyama,K., Miyoshi,Y., Suzuki,M.,
            Takahashi,E., Azuma,C., Murata,Y. and Nakamura,Y.
  TITLE     Isolation and characterization of a novel TP53-inducible gene,
            TP53TG5, which suppresses growth and shows cell cycle-dependent
            transition of expression
  JOURNAL   Genes Chromosomes Cancer 27 (4), 345-352 (2000)
   PUBMED   10719363
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL021578.4, AB017802.1 and BC036785.1.
            
            On Nov 23, 2018 this sequence version replaced NM_014477.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK295308.1, SRR5189667.252014.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2148093, SAMEA2148874
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000372726.5/ ENSP00000361811.3
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-8                 AL021578.4         89588-89595         c
            9-983               AB017802.1         84-1058
            984-989             BC036785.1         975-980
            990-2312            AL021578.4         83827-85149         c
FEATURES             Location/Qualifiers
     source          1..2312
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="20"
                     /map="20q13.12"
     gene            1..2312
                     /gene="TP53TG5"
                     /gene_synonym="C20orf10; CLG01"
                     /note="TP53 target 5"
                     /db_xref="GeneID:27296"
                     /db_xref="HGNC:HGNC:15856"
                     /db_xref="MIM:617316"
     exon            1..137
                     /gene="TP53TG5"
                     /gene_synonym="C20orf10; CLG01"
                     /inference="alignment:Splign:2.1.0"
     CDS             90..962
                     /gene="TP53TG5"
                     /gene_synonym="C20orf10; CLG01"
                     /note="TP53-inducible gene 5 protein"
                     /codon_start=1
                     /product="TP53-target gene 5 protein"
                     /protein_id="NP_055292.1"
                     /db_xref="CCDS:CCDS13352.1"
                     /db_xref="GeneID:27296"
                     /db_xref="HGNC:HGNC:15856"
                     /db_xref="MIM:617316"
                     /translation="MSPSAKKRPKNSRVSKMQDEKLRDETEQPVSKVIERNRLRTVLK
                     NLSLLKLLKSSNRRIQELHKLAKRCWHSLLSVPKILRISSGENSACNKTKQNNEEFQE
                     IGCSEKELKSKKLESTGDPKKKEYKEWKSQVQSGMRNKEKTSLAAMPRKEKHIEPEVP
                     RTSRDDSLNPGVQGRQPLTEGPRVIFIKPYRNRTPMGHMKQLDVADQWIWFEGLPTRI
                     HLPAPRVMCRSSTLRWVKRRCTRFCSASLEMPMWHPYKVDVTWTRARGASRGWRSRHQ
                     LKGRNGWRNSRVYK"
     exon            138..212
                     /gene="TP53TG5"
                     /gene_synonym="C20orf10; CLG01"
                     /inference="alignment:Splign:2.1.0"
     exon            213..343
                     /gene="TP53TG5"
                     /gene_synonym="C20orf10; CLG01"
                     /inference="alignment:Splign:2.1.0"
     exon            344..857
                     /gene="TP53TG5"
                     /gene_synonym="C20orf10; CLG01"
                     /inference="alignment:Splign:2.1.0"
     exon            858..2312
                     /gene="TP53TG5"
                     /gene_synonym="C20orf10; CLG01"
                     /inference="alignment:Splign:2.1.0"
     regulatory      958..963
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TP53TG5"
                     /gene_synonym="C20orf10; CLG01"
                     /note="hexamer: AATAAG"
     polyA_site      989
                     /gene="TP53TG5"
                     /gene_synonym="C20orf10; CLG01"
                     /note="major polyA site"
     regulatory      2281..2286
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TP53TG5"
                     /gene_synonym="C20orf10; CLG01"
                     /note="hexamer: AATAAT"
     polyA_site      2312
                     /gene="TP53TG5"
                     /gene_synonym="C20orf10; CLG01"
ORIGIN      
        1 agcctgagtg ctggctgaac tgagaggaac agggttggtg cctggcactg gtgttgctcc
       61 attcatctct gaggtctcac agccccagca tgagtccatc agcaaagaag aggcccaaga
      121 acagcagggt ttccaagatg caagatgaga aactgcggga cgagacagag cagcctgtga
      181 gcaaagtaat tgagcggaac cgtctgagaa cggtgttaaa aaacttgtcg ctcttgaagc
      241 tactcaagag ctcaaaccgc cggatccaag aactgcataa gctggccaaa aggtgttggc
      301 attcactgct cagtgttcca aagattctcc gcatctcctc tggggaaaac agtgcctgca
      361 ataaaacaaa acaaaataat gaagagttcc aggagatcgg gtgctccgag aaggaactca
      421 agtccaagaa attagagtcc acaggggacc ctaagaaaaa agagtacaag gagtggaagt
      481 cccaggtgca gtcagggatg aggaacaagg agaaaacgtc attggcggca atgccacgga
      541 aagaaaagca tatagagcct gaggttccaa ggacatcgag ggatgatagc ttgaaccctg
      601 gagtccaggg gaggcaacca ctcaccgagg gcccccgagt catcttcatt aagccctacc
      661 gcaatagaac tcccatgggg cacatgaagc agctggatgt agccgaccag tggatctggt
      721 ttgaggggct gcccacacga atccacctcc cggcgcccag ggtgatgtgc agatcctcca
      781 ccctgcgttg ggtcaagcgc cgctgcaccc gcttctgctc cgcatcactt gaaatgccta
      841 tgtggcatcc atacaaggtt gatgtgacct ggacgagagc cagaggtgcg agcagagggt
      901 ggagatcgcg ccatcagctg aaggggagga atgggtggcg aaattcacga gtctacaaat
      961 aagatcttcc atatggcacc taagacgaat actgcttact ctgcctgttt gtctggggct
     1021 gggaaggatg aaggaaagag gccttcggta gagggagcct gtgtcgcgac ttcaggcttc
     1081 ccccaccccc accccgaggc ccctaaggtc agtctagaac caaagaagcc agcgagcagc
     1141 acccctcccc cacctccgcg agctagtctc ctgagtggcg cgctctgtga agtcagggcg
     1201 ctcgtgtgct tcctgggtgc aaagtgcctc acaatcgccc cgcgagctcg caagaggaaa
     1261 ccgcggcgcg gaggcagcaa gtaacttgcc caggctcact cagctagaaa gtggcaggag
     1321 caagggctcc tggttgctcc ccattccatt ttcccaagaa agggaaaagg cgaaatgaga
     1381 gcctgctcag aagtcacgag gcaggcggaa tagccccagc accctgtagg tcatgcgcgt
     1441 gcattgcgac ctgattgtca aaaattgatt gtcaaaaact gattgcactg tggctggtgt
     1501 caaaaagtgg atgtcagctg ggcctccaaa tgtgtcctgc cttggtcaca gatcacagaa
     1561 ggcaccggat caggaggggg agctggtact gcatctctac tgctccaggg tgacatggca
     1621 ggtccaccct caatctgaag acctcaaccc caagccctgg tcgaccccat ctggccgggg
     1681 tcaccctctg tcggtaggag tcacagggtc ctaaccatgc cgttggggag aggaaagcca
     1741 agggagcccg agttttctcc ggacgaagac ctccatattc cccagaggca ggctgcatgg
     1801 agtgggcgcc ctcgggagag cagtggagcc atcgaggggc acagagctct ccgggattgg
     1861 gggtcagggc agcgatgcag atagatctcc agtttgggac agagggagaa cgattggatg
     1921 gactctcccc ccctcccacc ccgcccactc acacactcct ccccaccatt actgggcacc
     1981 aagactgggc atcagctgcc gcgcggacca gcctgggcgg agccacagcg cggggactgc
     2041 ttagcacctc atagtggctg ctgcgtgctc ccgagctcct gctcccagcg caatcttcct
     2101 ggagctcccc tacggtcggt gcctacctcc gcccccacca ccccgctaat tcccgtgcaa
     2161 attccacccc agtaaccact ttcagcggtc ttcccaccca gcttgcactc cagcccattt
     2221 cctgaacagt ctcccttgca gttcccttgc tgggtatttt caatcccatc aactttcgaa
     2281 aataatctct actcactctt ccattccatc aa
//
