LOCUS       NM_016212               1465 bp    mRNA    linear   PRI 12-JUN-2024
DEFINITION  Homo sapiens TP53 target 3 (TP53TG3), transcript variant 1, mRNA.
ACCESSION   NM_016212 XM_001126019
VERSION     NM_016212.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1465)
  AUTHORS   Barber,J.C., Hall,V., Maloney,V.K., Huang,S., Roberts,A.M.,
            Brady,A.F., Foulds,N., Bewes,B., Volleth,M., Liehr,T., Mehnert,K.,
            Bateman,M. and White,H.
  TITLE     16p11.2-p12.2 duplication syndrome; a genomic condition
            differentiated from euchromatic variation of 16p11.2
  JOURNAL   Eur J Hum Genet 21 (2), 182-189 (2013)
   PUBMED   22828807
REFERENCE   2  (bases 1 to 1465)
  AUTHORS   Sun,Y.V. and Kardia,S.L.
  TITLE     Identification of epistatic effects using a protein-protein
            interaction database
  JOURNAL   Hum Mol Genet 19 (22), 4345-4352 (2010)
   PUBMED   20736252
REFERENCE   3  (bases 1 to 1465)
  AUTHORS   Ng,C.C., Koyama,K., Okamura,S., Kondoh,H., Takei,Y. and Nakamura,Y.
  TITLE     Isolation and characterization of a novel TP53-inducible gene,
            TP53TG3
  JOURNAL   Genes Chromosomes Cancer 26 (4), 329-335 (1999)
   PUBMED   10534768
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC138907.2.
            
            On Jul 30, 2021 this sequence version replaced NM_016212.4.
            
            Sequence Note:.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7410570.623998.1,
                                           SRR14243140.9097482.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2142853
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000398682.5/ ENSP00000381672.4
            RefSeq Select criteria :: based on manual assertion
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-430               AC138907.2         124649-125078
            431-1465            AC138907.2         126250-127284
FEATURES             Location/Qualifiers
     source          1..1465
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16p11.2"
     gene            1..1465
                     /gene="TP53TG3"
                     /gene_synonym="P53TG3; TP53TG3A; TP53TG3E; TP53TG3F"
                     /note="TP53 target 3"
                     /db_xref="GeneID:24150"
                     /db_xref="HGNC:HGNC:30759"
                     /db_xref="MIM:617482"
     exon            1..430
                     /gene="TP53TG3"
                     /gene_synonym="P53TG3; TP53TG3A; TP53TG3E; TP53TG3F"
                     /inference="alignment:Splign:2.1.0"
     CDS             69..443
                     /gene="TP53TG3"
                     /gene_synonym="P53TG3; TP53TG3A; TP53TG3E; TP53TG3F"
                     /note="p53 target gene 3; TP53-inducible gene 3 protein"
                     /codon_start=1
                     /product="TP53-target gene 3 protein"
                     /protein_id="NP_057296.1"
                     /db_xref="CCDS:CCDS45475.1"
                     /db_xref="GeneID:24150"
                     /db_xref="HGNC:HGNC:30759"
                     /db_xref="MIM:617482"
                     /translation="MRASPCISQPAASWHPRPSALRPTAGSGPDTRTPGTVEDGSAPC
                     PAFRSPAVSPCGEEPCCFQISPAEETLELGRLVSPGNCDTLSPRAAGFYACHVRSLIP
                     CRSTKGRWPLTASAAGLSSFSG"
     exon            431..1465
                     /gene="TP53TG3"
                     /gene_synonym="P53TG3; TP53TG3A; TP53TG3E; TP53TG3F"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1445..1450
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TP53TG3"
                     /gene_synonym="P53TG3; TP53TG3A; TP53TG3E; TP53TG3F"
                     /note="hexamer: ATTAAA"
     polyA_site      1465
                     /gene="TP53TG3"
                     /gene_synonym="P53TG3; TP53TG3A; TP53TG3E; TP53TG3F"
                     /note="major polyA site"
ORIGIN      
        1 tcctcctgta gccccaccat ccaccgtggg gaacggtgga gagactacaa ctcccagtat
       61 gcaccgcgat gcgcgcctca ccctgcatct cccagcccgc agccagctgg catcctagac
      121 cctctgccct gcgaccaaca gccgggagcg gaccagacac cagaactccc ggaacggttg
      181 aagacggttc cgctccctgt cccgcctttc gcagcccagc agtttcgccc tgcggagagg
      241 agccttgctg tttccaaatc tctcctgctg aagagacatt ggagctaggg cggctagttt
      301 cacctggtaa ttgtgacacc ctgtctcctc gagctgcagg cttttatgct tgtcatgttc
      361 gaagtttgat accttgcaga tcaacaaagg gccggtggcc tctcactgcc tccgcggcag
      421 ggttgtcaag tttttcaggt taagtactgc acgactactc gcttctgaaa ctgatagaca
      481 ctgcctcagc tccgtgcagg gcagacgcac aagagcagaa tctccgtggg acatctctct
      541 ggagcatcaa tattactgca gtatttggaa gaaacaaatt taaataagtt ctaaggtgaa
      601 gaatggaaca tttaagacaa gtctggaaag tcatctgcct ttaataactg tcgtttgtcc
      661 ttaacgtcag actttctcca agaccaaaac tctaagaact tatttccatt cttacaaata
      721 gtaaaaatga taaatcatat caagtcaatt gaaagtcctg cctgctgctt tcctaaattg
      781 caatatggcc ttggtatggt tttatttgta cttttgtggg ggattcgtgg atctttagat
      841 taaaaaaaaa aaaataggtt tttgaacaat ttttgcaagt ttgcagctgt tagttattga
      901 tttatttttc caacccatct aattcttctg tctctctcct ctcctcaggc tcaataattc
      961 catgggtctc taaggctgtg tttattttct ttaaattttg ttgatttact tttatactcc
     1021 atttgatttt ttctatctct caccttttct cagactcagt catcccacag gtctgtaagg
     1081 ctctgttcat tttctttaaa cttctttttt ttttcctctc ctcagattgg ataaattata
     1141 ttgctatgtc tctgtttctg aactatagaa aagctcaaaa ttattatttt tatttctcat
     1201 tttttatatg gctatttttt ctctgctgat gtttcacatc tattcattta tgagaatatt
     1261 ttcctttgcc ctcatgagcg tgtttataat agctgccttc aaattcttgt ctgccgttta
     1321 catcttggac atcttggaga tggctactgc ctgcttttta tcttgtgtat ttattacatt
     1381 ttcacgtgtc ttcacgcatc ccttgaattg gaaattgtgc cctggagact gtatacaaga
     1441 ctggattaaa aagactggat tctgt
//
