LOCUS       NM_138349               1473 bp    mRNA    linear   PRI 06-JUN-2024
DEFINITION  Homo sapiens tumor protein p53 inducible protein 13 (TP53I13),
            transcript variant 1, mRNA.
ACCESSION   NM_138349
VERSION     NM_138349.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1473)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 1473)
  AUTHORS   Hata,T., Ogawa,T., Yokoyama,T.A., Fukushige,S., Horii,A. and
            Furukawa,T.
  TITLE     DSCP1, a novel TP53-inducible gene, is upregulated by strong
            genotoxic stresses and its overexpression inhibits tumor cell
            growth in vitro
  JOURNAL   Int J Oncol 24 (3), 513-520 (2004)
   PUBMED   14767535
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL551604.3 and BC001593.2.
            
            On Nov 22, 2018 this sequence version replaced NM_138349.3.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR3476690.557732.1, AB110209.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000301057.8/ ENSP00000301057.7
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-20                AL551604.3         58-77
            21-1473             BC001593.2         1-1453
FEATURES             Location/Qualifiers
     source          1..1473
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q11.2"
     gene            1..1473
                     /gene="TP53I13"
                     /gene_synonym="DSCP1"
                     /note="tumor protein p53 inducible protein 13"
                     /db_xref="GeneID:90313"
                     /db_xref="HGNC:HGNC:25102"
     exon            1..130
                     /gene="TP53I13"
                     /gene_synonym="DSCP1"
                     /inference="alignment:Splign:2.1.0"
     CDS             59..1240
                     /gene="TP53I13"
                     /gene_synonym="DSCP1"
                     /note="isoform a precursor is encoded by transcript
                     variant 1; damage-stimulated cytoplasmic protein 1"
                     /codon_start=1
                     /product="tumor protein p53-inducible protein 13 isoform a
                     precursor"
                     /protein_id="NP_612358.3"
                     /db_xref="CCDS:CCDS42289.1"
                     /db_xref="GeneID:90313"
                     /db_xref="HGNC:HGNC:25102"
                     /translation="MAPPPPSPQLLLLAALARLLGPSEVMAGPAEEAGAHCPESLWPL
                     PPQVSPRVTYTRVSPGQAEDVTFLYHPCAHPWLKLQLALLAYACMANPSLTPDFSLTQ
                     DRPLVLTAWGLALEMAWVEPAWAAHWLMRRRRRKQRKKKAWIYCESLSGPAPSEPTPG
                     RGRLCRRGCVQALALAFALRSWRPPGTEVTSQGPRQPSSSGAKRRRLRAALGPQPTRS
                     ALRFPSASPGSLKAKQSMAGIPGRESNAPSVPTVSLLPGAPGGNASSRTEAQVPNGQG
                     SPGGCVCSSQASPAPRAAAPPRAARGPTPRTEEAAWAAMALTFLLVLLTLATLCTRLH
                     RNFRRGESIYWGPTADSQDTVAAVLKRRLLQPSRRVKRSRRRPLLPPTPDSGPEGESS
                     E"
     exon            131..199
                     /gene="TP53I13"
                     /gene_synonym="DSCP1"
                     /inference="alignment:Splign:2.1.0"
     exon            200..241
                     /gene="TP53I13"
                     /gene_synonym="DSCP1"
                     /inference="alignment:Splign:2.1.0"
     exon            242..370
                     /gene="TP53I13"
                     /gene_synonym="DSCP1"
                     /inference="alignment:Splign:2.1.0"
     exon            371..571
                     /gene="TP53I13"
                     /gene_synonym="DSCP1"
                     /inference="alignment:Splign:2.1.0"
     exon            572..1127
                     /gene="TP53I13"
                     /gene_synonym="DSCP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1128..1473
                     /gene="TP53I13"
                     /gene_synonym="DSCP1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1454..1459
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TP53I13"
                     /gene_synonym="DSCP1"
                     /note="hexamer: ATTAAA"
     polyA_site      1473
                     /gene="TP53I13"
                     /gene_synonym="DSCP1"
                     /note="major polyA site"
ORIGIN      
        1 gcgcgctccc tcgctggcgg agcggctggg cggcgggccg ggcccggggc cgcttggaat
       61 ggcgcctcct ccgccttcgc cccaactgct tctcctggca gccctcgcga ggctcctggg
      121 tcccagcgag gtgatggctg gaccggcgga ggaggcggga gcccattgtc ccgagagcct
      181 gtggcctctg cctccgcagg tgtcaccaag agtgacctac acacgagtga gcccagggca
      241 ggctgaggat gtcaccttcc tctaccaccc ctgtgcccat ccctggctga agctccagct
      301 tgccctcctg gcctatgctt gtatggctaa cccttccctc acccctgact tcagcctcac
      361 gcaggatcgg cccctggtgc tgactgcatg ggggctggcg ctggagatgg cctgggtaga
      421 gccagcctgg gctgcccact ggctgatgag gaggcggagg aggaagcaga ggaagaagaa
      481 ggcatggatc tactgtgaaa gcctttcagg gcctgctccc tccgagccaa ctcccggtag
      541 agggaggctg tgccgaagag ggtgtgtgca ggccctggct ctggcctttg ctctgcggag
      601 ctggcggccc cctggcacag aggtgacatc tcaagggccc aggcagccct cttctagtgg
      661 tgccaagagg cggaggctgc gggctgccct tggtccccag cccactcgct cagccctgag
      721 gtttccctct gcttccccag ggagcttgaa ggccaagcag tccatggcgg gaatccctgg
      781 tagggagagt aatgccccat ctgtgcccac tgtctccctg ctgccggggg cgcctggagg
      841 caatgccagc tccaggacag aggctcaggt gcccaacggg caaggcagcc cagggggctg
      901 tgtctgttca agtcaggctt ccccggcccc tcgcgcagca gcgcctccac gggcagcccg
      961 gggccccacc ccacgcactg aagaggccgc ctgggctgcc atggccctga ccttcctgct
     1021 ggtgctgctc accctggcca cgctctgcac acggctgcac agaaacttcc gacgcgggga
     1081 gagcatctac tgggggccca cagcggacag ccaggacaca gtggctgctg tgctgaagcg
     1141 gaggctgctg cagccctcgc gccgggtcaa gcgctcgcgc cggagacccc tcctcccgcc
     1201 cacgccggac agcggcccgg aaggcgagag ctcggagtga cggcctggga cctgccactg
     1261 tggcgtgcgg ctcctccccg cgccgcgagg ccgcgacctc tgccacgtgg accgcgcgcg
     1321 gggcgctccc tggtggcgat ggcgcggcac tggccgagca ctgcgggggc tttcctcctt
     1381 gttggttgct gagtgggcgg ccaaggggag aaaaggagcc gcttctgcct cccttgccaa
     1441 aactccgttt ctaattaaat tatttttagt aga
//
