LOCUS       NM_001162501           18280 bp    mRNA    linear   PRI 19-SEP-2024
DEFINITION  Homo sapiens trinucleotide repeat containing adaptor 6B (TNRC6B),
            transcript variant 1, mRNA.
ACCESSION   NM_001162501
VERSION     NM_001162501.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 18280)
  AUTHORS   Yang,Q., Ou,S., Zhou,X., Yi,S., Lin,L., Yi,S., Zhang,S., Qin,Z. and
            Luo,J.
  TITLE     Novel variants in TNRC6B cause global developmental delay with
            speech and behavioral abnormalities, short stature, low body
            weight, cafe-au-lait spots, and metabolic abnormality
  JOURNAL   Mol Genet Genomic Med 12 (2), e2408 (2024)
   PUBMED   38404251
  REMARK    GeneRIF: Novel variants in TNRC6B cause global developmental delay
            with speech and behavioral abnormalities, short stature, low body
            weight, cafe-au-lait spots, and metabolic abnormality.
REFERENCE   2  (bases 1 to 18280)
  AUTHORS   Cho,N.H., Cheveralls,K.C., Brunner,A.D., Kim,K., Michaelis,A.C.,
            Raghavan,P., Kobayashi,H., Savy,L., Li,J.Y., Canaj,H., Kim,J.Y.S.,
            Stewart,E.M., Gnann,C., McCarthy,F., Cabrera,J.P., Brunetti,R.M.,
            Chhun,B.B., Dingle,G., Hein,M.Y., Huang,B., Mehta,S.B.,
            Weissman,J.S., Gomez-Sjoberg,R., Itzhak,D.N., Royer,L.A., Mann,M.
            and Leonetti,M.D.
  TITLE     OpenCell: Endogenous tagging for the cartography of human cellular
            organization
  JOURNAL   Science 375 (6585), eabi6983 (2022)
   PUBMED   35271311
REFERENCE   3  (bases 1 to 18280)
  AUTHORS   Johnson,S.T., Chu,Y., Liu,J. and Corey,D.R.
  TITLE     Impact of scaffolding protein TNRC6 paralogs on gene expression and
            splicing
  JOURNAL   RNA 27 (9), 1004-1016 (2021)
   PUBMED   34108231
  REMARK    GeneRIF: Impact of scaffolding protein TNRC6 paralogs on gene
            expression and splicing.
REFERENCE   4  (bases 1 to 18280)
  AUTHORS   Chen,C., Jiang,L., Zhang,Y. and Zheng,W.
  TITLE     FOXA1-induced LINC01207 facilitates head and neck squamous cell
            carcinoma via up-regulation of TNRC6B
  JOURNAL   Biomed Pharmacother 128, 110220 (2020)
   PUBMED   32450521
  REMARK    GeneRIF: FOXA1-induced LINC01207 facilitates head and neck squamous
            cell carcinoma via up-regulation of TNRC6B.
REFERENCE   5  (bases 1 to 18280)
  AUTHORS   Rasch,F., Weber,R., Izaurralde,E. and Igreja,C.
  TITLE     4E-T-bound mRNAs are stored in a silenced and deadenylated form
  JOURNAL   Genes Dev 34 (11-12), 847-860 (2020)
   PUBMED   32354837
REFERENCE   6  (bases 1 to 18280)
  AUTHORS   Till,S., Lejeune,E., Thermann,R., Bortfeld,M., Hothorn,M.,
            Enderle,D., Heinrich,C., Hentze,M.W. and Ladurner,A.G.
  TITLE     A conserved motif in Argonaute-interacting proteins mediates
            functional interactions through the Argonaute PIWI domain
  JOURNAL   Nat Struct Mol Biol 14 (10), 897-903 (2007)
   PUBMED   17891150
REFERENCE   7  (bases 1 to 18280)
  AUTHORS   Schneider,M.D., Najand,N., Chaker,S., Pare,J.M., Haskins,J.,
            Hughes,S.C., Hobman,T.C., Locke,J. and Simmonds,A.J.
  TITLE     Gawky is a component of cytoplasmic mRNA processing bodies required
            for early Drosophila development
  JOURNAL   J Cell Biol 174 (3), 349-358 (2006)
   PUBMED   16880270
REFERENCE   8  (bases 1 to 18280)
  AUTHORS   Meister,G., Landthaler,M., Peters,L., Chen,P.Y., Urlaub,H.,
            Luhrmann,R. and Tuschl,T.
  TITLE     Identification of novel argonaute-associated proteins
  JOURNAL   Curr Biol 15 (23), 2149-2155 (2005)
   PUBMED   16289642
REFERENCE   9  (bases 1 to 18280)
  AUTHORS   Dunham,I., Shimizu,N., Roe,B.A., Chissoe,S., Hunt,A.R.,
            Collins,J.E., Bruskiewich,R., Beare,D.M., Clamp,M., Smink,L.J.,
            Ainscough,R., Almeida,J.P., Babbage,A., Bagguley,C., Bailey,J.,
            Barlow,K., Bates,K.N., Beasley,O., Bird,C.P., Blakey,S.,
            Bridgeman,A.M., Buck,D., Burgess,J., Burrill,W.D., O'Brien,K.P. et
            al.
  TITLE     The DNA sequence of human chromosome 22
  JOURNAL   Nature 402 (6761), 489-495 (1999)
   PUBMED   10591208
  REMARK    Erratum:[Nature 2000 Apr 20;404(6780):904]
REFERENCE   10 (bases 1 to 18280)
  AUTHORS   Gubin,A.N., Njoroge,J.M., Bouffard,G.G. and Miller,J.L.
  TITLE     Gene expression in proliferating human erythroid cells
  JOURNAL   Genomics 59 (2), 168-177 (1999)
   PUBMED   10409428
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BX952326.1, AK294519.1, BQ009349.1, AL022238.1, BX537577.1,
            DB147781.1, AL831862.1, BU584176.1 and CA312515.1.
            
            On Nov 22, 2018 this sequence version replaced NM_001162501.1.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803613.62021.1,
                                           SRR1803611.74886.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2148093, SAMEA2149004
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000454349.7/ ENSP00000401946.2
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-645               BX952326.1         2-646
            646-6028            AK294519.1         637-6019
            6029-6272           BQ009349.1         5-248               c
            6273-11293          AL022238.1         26029-31049
            11294-12380         BX537577.1         1-1087
            12381-12650         DB147781.1         46-315
            12651-15369         BX537577.1         1358-4076
            15370-17504         AL831862.1         186-2320
            17505-17641         BU584176.1         94-230
            17642-18244         CA312515.1         61-663              c
            18245-18280         CA312515.1         18-53               c
FEATURES             Location/Qualifiers
     source          1..18280
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="22"
                     /map="22q13.1"
     gene            1..18280
                     /gene="TNRC6B"
                     /gene_synonym="GDSBA"
                     /note="trinucleotide repeat containing adaptor 6B"
                     /db_xref="GeneID:23112"
                     /db_xref="HGNC:HGNC:29190"
                     /db_xref="MIM:610740"
     exon            1..216
                     /gene="TNRC6B"
                     /gene_synonym="GDSBA"
                     /inference="alignment:Splign:2.1.0"
     CDS             212..5713
                     /gene="TNRC6B"
                     /gene_synonym="GDSBA"
                     /note="isoform 1 is encoded by transcript variant 1;
                     trinucleotide repeat-containing gene 6B protein;
                     trinucleotide repeat containing 6B"
                     /codon_start=1
                     /product="trinucleotide repeat-containing gene 6B protein
                     isoform 1"
                     /protein_id="NP_001155973.1"
                     /db_xref="CCDS:CCDS54533.1"
                     /db_xref="GeneID:23112"
                     /db_xref="HGNC:HGNC:29190"
                     /db_xref="MIM:610740"
                     /translation="MREKEQEREEQLMEDKKRKKEDKKKKEATQKVTEQKTKVPEVTK
                     PSLSQPTAASPIGSSPSPPVNGGNNAKRVAVPNGQPPSAARYMPREVPPRFRCQQDHK
                     VLLKRGQPPPPSCMLLGGGAGPPPCTAPGANPNNAQVTGALLQSESGTAPDSTLGGAA
                     ASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTTDN
                     NSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKAKSVQSSNSTTE
                     NNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSSA
                     QVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLSSPNPMENK
                     GMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSGNNGNNG
                     KEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQ
                     GEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSSTG
                     SEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWG
                     QTQIKQDTVWDIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGDAPSQSNQMKSGWGE
                     LSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQ
                     GWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGNASLASKGGWE
                     DCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRPSNS
                     SWSSGPQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNS
                     QGGPAPREPNLPTPMTSKSASVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGAST
                     TGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSA
                     SSHNSASWGQGGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVG
                     SLSDKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKLTLPFSNQD
                     GCLGDEAPCSPFSPSPSYKLSPSGSTLPNVSLGAIGTGLNPQNFAARQGGSHGLFGNS
                     TAQSRGLHTPVQPLNSSPSLRAQVPPQFISPQVSASMLKQFPNSGLSPGLFNVGPQLS
                     PQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSAL
                     QQQQQQQQRQPGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKGPIPGYGSGFSSG
                     GMDYGMVGGKEAGTESRFKQWTSMMEGLPSVATQEANMHKNGAIVAPGKTRGGSPYNQ
                     FDIIPGDTLGGHTGPAGDSWLPAKSPPTNKIGSKSSNASWPPEFQPGVPWKGIQNIDP
                     ESDPYVTPGSVLGGTATSPIVDTDHQLLRDNTTGSNSSLNTSLPSPGAWPYSASDNSF
                     TNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTPLPRPPPGLTNPKP
                     SSPWSSTAPRSVRGWGTQDSRLASASTWSDGGSVRPSYWLVLHNLTPQIDGSTLRTIC
                     MQHGPLLTFHLNLTQGTALIRYSTKQEAAKAQTALHMCVLGNTTILAEFATDDEVSRF
                     LAQAQPPTPAATPSAPAAGWQSLETGQNQSDPVGPALNLFGGSTGLGQWSSSAGGSSG
                     ADLAGASLWGPPNYSSSLWGVPTVEDPHRMGSPAPLLPGDLLGGGSDSI"
     exon            217..304
                     /gene="TNRC6B"
                     /gene_synonym="GDSBA"
                     /inference="alignment:Splign:2.1.0"
     exon            305..326
                     /gene="TNRC6B"
                     /gene_synonym="GDSBA"
                     /inference="alignment:Splign:2.1.0"
     exon            327..668
                     /gene="TNRC6B"
                     /gene_synonym="GDSBA"
                     /inference="alignment:Splign:2.1.0"
     exon            669..3017
                     /gene="TNRC6B"
                     /gene_synonym="GDSBA"
                     /inference="alignment:Splign:2.1.0"
     exon            3018..3176
                     /gene="TNRC6B"
                     /gene_synonym="GDSBA"
                     /inference="alignment:Splign:2.1.0"
     exon            3177..3352
                     /gene="TNRC6B"
                     /gene_synonym="GDSBA"
                     /inference="alignment:Splign:2.1.0"
     exon            3353..3427
                     /gene="TNRC6B"
                     /gene_synonym="GDSBA"
                     /inference="alignment:Splign:2.1.0"
     exon            3428..3473
                     /gene="TNRC6B"
                     /gene_synonym="GDSBA"
                     /inference="alignment:Splign:2.1.0"
     exon            3474..3622
                     /gene="TNRC6B"
                     /gene_synonym="GDSBA"
                     /inference="alignment:Splign:2.1.0"
     exon            3623..3793
                     /gene="TNRC6B"
                     /gene_synonym="GDSBA"
                     /inference="alignment:Splign:2.1.0"
     exon            3794..3919
                     /gene="TNRC6B"
                     /gene_synonym="GDSBA"
                     /inference="alignment:Splign:2.1.0"
     exon            3920..4051
                     /gene="TNRC6B"
                     /gene_synonym="GDSBA"
                     /inference="alignment:Splign:2.1.0"
     exon            4052..4147
                     /gene="TNRC6B"
                     /gene_synonym="GDSBA"
                     /inference="alignment:Splign:2.1.0"
     exon            4148..4331
                     /gene="TNRC6B"
                     /gene_synonym="GDSBA"
                     /inference="alignment:Splign:2.1.0"
     exon            4332..4469
                     /gene="TNRC6B"
                     /gene_synonym="GDSBA"
                     /inference="alignment:Splign:2.1.0"
     exon            4470..4646
                     /gene="TNRC6B"
                     /gene_synonym="GDSBA"
                     /inference="alignment:Splign:2.1.0"
     exon            4647..4793
                     /gene="TNRC6B"
                     /gene_synonym="GDSBA"
                     /inference="alignment:Splign:2.1.0"
     exon            4794..4889
                     /gene="TNRC6B"
                     /gene_synonym="GDSBA"
                     /inference="alignment:Splign:2.1.0"
     exon            4890..5114
                     /gene="TNRC6B"
                     /gene_synonym="GDSBA"
                     /inference="alignment:Splign:2.1.0"
     exon            5115..5185
                     /gene="TNRC6B"
                     /gene_synonym="GDSBA"
                     /inference="alignment:Splign:2.1.0"
     exon            5186..5325
                     /gene="TNRC6B"
                     /gene_synonym="GDSBA"
                     /inference="alignment:Splign:2.1.0"
     exon            5326..18280
                     /gene="TNRC6B"
                     /gene_synonym="GDSBA"
                     /inference="alignment:Splign:2.1.0"
     regulatory      18256..18261
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TNRC6B"
                     /gene_synonym="GDSBA"
                     /note="hexamer: AATAAA"
     polyA_site      18280
                     /gene="TNRC6B"
                     /gene_synonym="GDSBA"
                     /note="major polyA site"
ORIGIN      
        1 agagacagag agggagagag agagcaagag ggagagtgtg tgagagagag ttagttcaag
       61 ccaaaatggc cgacagagtc tctgctggtt tctgaatatt taaaatacaa aaaaacagat
      121 agacaaaaag aattcatttt ttggaccttt tttcatttcc atttctacct tgtatgcctc
      181 aatttgctgg atttaagcac tgctgcactt tatgagagag aaggagcaag aaagggaaga
      241 acagttaatg gaagacaaga aaaggaagaa agaggataaa aagaaaaaag aagccactca
      301 gaaggtcacg gaacaaaaaa ccaaagtgcc cgaagtgacg aaaccaagtt taagccaacc
      361 aacggccgcc agcccaattg gcagctctcc atcgccacca gtcaatggtg gcaacaatgc
      421 caaaagggtg gcagtgccga acggacaacc gccaagcgcc gcccgctaca tgcctcggga
      481 ggtgccgccg cgattccgtt gccagcagga ccacaaagtg ttactaaaac gtgggcagcc
      541 ccctccaccg tcctgcatgc tccttggggg tggggcaggg cctcctccct gcacagcacc
      601 tggagcaaac ccaaacaacg cacaagtgac aggagcgctg ctgcagagtg agagtgggac
      661 tgcgccagac tcaacccttg gaggtgctgc tgcttcaaat tatgcaaatt ccacttgggg
      721 ctcgggagcc tcctccaaca acggcacctc ccccaaccca attcacatct gggacaaggt
      781 gattgtagac gggtctgaca tggaagagtg gccttgtatt gccagcaaag acactgaatc
      841 ttcttccgaa aacaccaccg ataacaacag tgcctcgaac cctggctctg agaagagcac
      901 tctgccagga agcaccacta gtaacaaagg aaaagggagc cagtgccagt ctgcaagttc
      961 tgggaacgaa tgtaatcttg gggtctggaa atctgaccct aaggctaaat ctgttcaatc
     1021 ttccaactct actacagaga acaacaatgg actaggaaat tggaggaatg tgagtggtca
     1081 ggatagaatt ggacctggct ctggcttcag caactttaac ccaaatagca acccatctgc
     1141 ctggccagca ctggtccaag aaggaacttc taggaaaggg gcattggaaa cagataatag
     1201 taattccagt gcacaggtta gcacagtagg tcagacatcc agggaacagc agtcaaagat
     1261 ggaaaatgcg ggtgttaatt ttgttgtctc tggcagagaa caggctcaaa ttcataacac
     1321 tgatggacca aaaaatggaa acactaactc cttgaactta agttcaccaa accccatgga
     1381 gaataaggga atgccctttg gaatgggctt ggggaacacc tccaggagca ctgatgcccc
     1441 ttcacaaagc actggagatc gaaagactgg gagtgttgga tcttggggtg cagctagggg
     1501 gccttctgga actgacacag tctctggaca aagcaattct ggaaacaatg ggaacaatgg
     1561 aaaagagaga gaggactcct ggaaaggagc ttctgttcag aaatcaactg ggtcaaaaaa
     1621 tgactcttgg gacaacaata acaggtctac gggtgggtcc tggaactttg gcccccagga
     1681 ctctaatgac aacaaatggg gtgaagggaa caaaatgaca tctggggtct ctcagggaga
     1741 atggaaacag ccgactgggt ctgatgagtt gaaaattgga gaatggagtg gtccaaacca
     1801 accaaattct agcactggag catgggacaa tcaaaagggc caccccctcc ctgaaaacca
     1861 aggcaatgcc caggctccct gttggggaag atcttccagc tccacaggaa gtgaagttgg
     1921 aggtcaaagc actggaagca accacaaagc aggaagtagt gacagtcata actctggccg
     1981 tcggtcgtac aggcccacac atcctgattg tcaggctgtc ttgcagactc ttttgagccg
     2041 aactgatttg gaccccaggg tgctctcaaa cactggctgg ggccaaactc aaattaagca
     2101 ggacacagtg tgggacattg aagaggtgcc aaggcctgag gggaaatctg acaaaggaac
     2161 tgaggggtgg gagagcgctg ccacacagac caagaactca gggggctggg gagatgcacc
     2221 cagccaaagc aatcaaatga agtctggatg gggggagctc tcagcctcta cagagtggaa
     2281 agaccccaag aacacaggag gctggaatga ctacaagaac aacaactctt ccaactgggg
     2341 aggaggacga cctgatgaaa agacaccttc ctcttggaat gagaatccca gcaaggatca
     2401 ggggtgggga ggtggacgcc agcccaatca aggatggtct tctggaaaga atggttgggg
     2461 ggaggaagtc gatcagacaa aaaacagcaa ttgggaaagt tctgcaagta aacctgtgtc
     2521 tgggtggggt gaaggagggc agaatgaaat cgggacttgg ggtaatggtg gcaatgcaag
     2581 cctagcttca aaaggtgggt gggaggattg caaaagatcc ccagcatgga atgagacggg
     2641 ccgacagccc aattcctgga ataaacaaca ccaacagcag cagcccccac agcagccgcc
     2701 gccaccacaa ccagaggctt ctggttcgtg gggaggccca cccccaccac ctccaggcaa
     2761 cgttcgacct tccaattcca gctggagcag cgggccacag cctgcaacac ctaaggatga
     2821 ggaacccagt ggttgggaag agccatcccc acagtcaatt agtcggaaaa tggacattga
     2881 tgatggcact tcagcatggg gagaccctaa cagttataac tacaagaatg tgaatctgtg
     2941 ggataagaat tcccaagggg gcccagcacc tcgagaacca aacctgccca ccccaatgac
     3001 cagtaaatcg gcatcagtct ggagcaaaag cacaccacct gctccagata atggtacttc
     3061 cgcttggggt gagccaaatg aaagcagtcc tgggtggggc gagatggatg atacaggagc
     3121 atcgaccaca ggctggggga acacgcccgc caacgctccc aatgccatga agcctaattc
     3181 caaatctatg caagacggct ggggggagag tgacgggcca gtcacaggag ctcgccatcc
     3241 cagctgggaa gaggaggagg atggaggagt ctggaacacc actggctctc agggcagtgc
     3301 ttcctcccac aactcagcaa gctggggaca aggaggaaag aaacaaatga agtgctcact
     3361 caaaggagga aacaatgatt catggatgaa tcctcttgcc aaacagtttt caaatatggg
     3421 attgctgagt cagactgaag ataatccaag cagcaaaatg gatttgtctg taggaagcct
     3481 ttcagataaa aaatttgatg tggacaagcg agcgatgaat ctcggggatt ttaatgatat
     3541 catgaggaag gatcgatctg ggttccgtcc acctaattcc aaagacatgg gaaccacaga
     3601 tagtgggcct tattttgaga agctgacttt gcctttctcc aatcaagatg ggtgccttgg
     3661 ggatgaggct ccctgctctc ccttctcccc ttctcccagc tacaagctgt ctccctctgg
     3721 ttccacacta cccaacgtca gccttggagc aatcggcaca gggctcaacc cccaaaactt
     3781 cgctgctaga caaggcggta gtcatggttt gtttggaaac agcacagcac aatcgagagg
     3841 tctgcacaca cccgtgcagc cactaaattc ttctcccagt ctccgggcgc aagtgcctcc
     3901 ccagtttatt tccccccagg tttctgcctc aatgctcaag cagtttccca acagtggcct
     3961 gagtccaggt cttttcaatg tggggcccca gttatctcct caacaaattg ccatgctgag
     4021 ccagcttcca caaattcccc agtttcagtt ggcatgtcag cttctcttgc agcagcagca
     4081 acagcagcag ttgttacaga accagagaaa gatttctcaa gctgtacgcc aacagcaaga
     4141 gcagcagctg gctcgaatgg tgagtgcact gcagcagcag cagcagcagc agcagaggca
     4201 gccaggcatg aagcactcgc cctctcatcc tgttgggccc aagccgcatc tggacaacat
     4261 ggtacccaac gcattgaatg tggggctccc agaccttcaa accaaagggc caatacctgg
     4321 atatggttct ggcttcagct ctggcggcat ggactatggc atggttggtg ggaaggaggc
     4381 tggaaccgag tctcgcttta aacagtggac ctccatgatg gaggggctgc cctctgtagc
     4441 cacacaggaa gccaatatgc acaaaaatgg cgctatagtg gcccctggta aaacccgggg
     4501 agggtcaccg tacaaccagt ttgatatcat ccctggtgac acactgggtg gccatacggg
     4561 tcctgctggt gatagctggt tacctgccaa atctccacca acaaataaaa tcggaagtaa
     4621 atccagcaat gccagttggc ctccagaatt ccaaccagga gtgccatgga aaggtatcca
     4681 aaacattgac cctgaatctg acccctatgt caccccagga agtgtgctgg ggggtacagc
     4741 cacatctccc attgtagata ctgaccacca actgctgcgg gataacacca cagggtctaa
     4801 ttcttccctc aacacctcgc tgccttcacc tggtgcctgg ccctacagtg cctctgacaa
     4861 ctcctttacc aacgttcata gcacttcagc aaagttccct gattacaaat caacatggtc
     4921 cccagatccc ataggacaca accccactca tctctccaac aagatgtgga aaaaccatat
     4981 ttcctccagg aacactacac cgctgccccg cccacctcct ggtctgacca accccaaacc
     5041 atcatctccc tggagcagca cagcaccccg atcagtcagg gggtggggga cacaggactc
     5101 acggctcgcc tcggcctcta cctggagtga tggtggctca gttcgtccta gttactggct
     5161 ggttcttcac aatctcaccc cacagattga tgggtcaacc ttgagaacga tctgcatgca
     5221 gcatggccca ctgctgacat tccatctgaa tctaacccag ggcactgccc tgatccgata
     5281 cagcaccaaa caggaggcgg ccaaggccca aactgcactg cacatgtgtg tgttgggaaa
     5341 cactaccatc cttgctgagt ttgccactga tgatgaagtc agccgctttc tggcacaagc
     5401 tcagccccct acacctgcag caaccccaag tgcgccagct gcggggtggc agtcgctgga
     5461 gaccggccag aaccagtcag atcccgtggg acctgctctg aatctttttg gtgggtccac
     5521 tgggctcggg cagtggagca gcagcgctgg tggcagcagc ggggccgatc ttgctggcgc
     5581 ttcattgtgg gggcccccaa actattcttc tagcttatgg ggagtcccaa cggtggaaga
     5641 tccccatagg atgggcagcc ctgctccttt actacctggt gaccttctgg gaggagggtc
     5701 ggattcaatc tgaacttaga actttcaact ctgacctcgt gacctttttt ggaacagcag
     5761 cagcactaac ttgacctttt cgtttttttt ttcaacttgc aataaataca tttttaaaag
     5821 gaaaaaagaa aacggagaga aaaaaaggtg ggtcattgac agactgtctg agcacatagt
     5881 tgcctccctt ataacttcag ttttttcgtt tggaatatga atccaaaaag agaacatatc
     5941 actcttgaaa tacttgaatc atgaacgcca acctagaaag acaatgtgaa gcaagtacac
     6001 ataccattta aatttaaaca caaaaaaatt aaaaaaatta gtttctagtt tttcactttt
     6061 ttcatgttat atggaagttg ttgctaagaa acatatatac tgaaaaaaaa tagcttttta
     6121 actttgtttg cactgggtgt gtttccgtcc ttaggtctac catgtttggg agggagggaa
     6181 attcaaaaga attgttgggg gaggggggag ggaagacttg acggagcctc actttaaaaa
     6241 caaaaacaca aaaaacctaa aaaaaaaaaa aaggaaaaaa tttgtgattg gctggttgat
     6301 aaataccagt gtgttctggc acatgtaact gcccaggcat gctcgttctg gtgtgtgtgt
     6361 gcacgtgtgt tcatgtgcat tcgcgtgcat ccttctctgt ctctgtgtgt gtgcctgtgt
     6421 tcttcccttc tcccctgccc caccctgact tctcagaaag ctgcatcgct gacagtctgc
     6481 aggctggctg gccggcccat ctgcttttta ttttattttt ttaactatga gaacacacag
     6541 gcccggagag ccactgctac taaagcaact ccattgggct gcattaagat gaacagagtg
     6601 ctttttaatg atgaaagcag ggagctcctt tccatttgca acttagcctg aatgtggggt
     6661 ttctctggct gttcttttga cctagcagta gagtggagca ctgccaagtc caaaaaacta
     6721 gagcaggagg tacctcttgg agcaacggtg tgtttatttc tgtttttttt tttttttaag
     6781 tgaatggcca ccaggcacat ctgagtatct gttaagtttc atgcaggcct tttcgttagt
     6841 ttgaaatggg aacggaagat aacttttgat gatgcgatgt ctcaaaaaca gagaaacttt
     6901 gttccctctt tccttatgat caggtttgag aaattcttca aaaaattagg tgaagttgag
     6961 ttacatattt ctgttggttg gttctctttt tcattttatg aaaacagaaa agaataagtg
     7021 gtgagcagcc tcctgaaagc atctgcagct actccctctg ctcctttctc gccgagcgtt
     7081 acctgtgcca ggccgtggcg cgttacagca ccaggccatc actgacagaa acgtttactt
     7141 aacgaatgtt cttaaaccag tgtgtacttc aagcgtttcc ttttgtttct ctgtgttgtg
     7201 tatttcctgt gtatgtggtt ttgcttaggc aggtataact tagcgaagac ttttaagtat
     7261 tgcacctttt tttgattttt gacctcttcc ccccaccttg taattttgct tttttaattt
     7321 cggtatttaa atactttttt ttttttttaa gcatcaatgt agtagtactc tgggccgaac
     7381 aggggtcaac gtttaatcta cagttatcac caacatgtat gtacttatgt cggaatcaaa
     7441 atgtatcaaa ctgcttattg tgaagagaat tatagcagac ctgaaggggg cgaaaaacca
     7501 gatagggtgg ggggatggat gccggtgacg tgctagcact tgtgtggaca tcccagtctg
     7561 cattatgctg tttaacataa agtgccgaca ttttgtacca gcaaatacct gcccattcca
     7621 acccttggtg ggagcagacc tctactgtcc tctgtaactt gctgctattg aggacaaggg
     7681 agtttttctt tctttagcgt cttcagtgaa ggatacaata caacaatgcc taatgtattt
     7741 gactttttag cttgtgtctg tgtgtaggtg ggtgggtggg tgtgtatagg aaaagcctaa
     7801 aacaagttat ttgcatttca gtggttttgt gagacaaaga atgggaaatt ctgtagccct
     7861 tctggcttac cctgttgatt ataaacctag cctcaaaaga gattgacagg catgactcaa
     7921 gtgagtgttc acatatacaa gcctgcatga gccctctgtg ggtaggtggt cacacttggc
     7981 atctgcagca ttgacgtggc cccgctgggt gccttgagca tgccctcttc ctgctctgca
     8041 atttgaatca ccaccgtgcc ccttccacca ctgttcccca tgcaaaagct ctgcttccag
     8101 cagcccccac tgaccgctct ctgtgtggag caaagtgctg tcgtgcggtg accaccaggt
     8161 gaagagcagc ttgtattcag acatctagag aaggttaaat cttagtgtcc ctgggccagg
     8221 agcatatccc aaggctcctg cgagccagtg gcgaccctgt ccactgccgc tcttggttca
     8281 ctgctgtgtc ctgccccacc ctcctctcct cctgcctgtt ggttccttga cctgcactat
     8341 gggttagttg agttccttac gatactacgg tgaaagccgg gtgctagagc ccctcttgtt
     8401 tacaagacat aatgagggat ttgaaatatg taaaaataaa catgagaagc taaaatgttc
     8461 ttccatcata agcttaaagg gaaaaaaact aaaaacttta aaaaaaaaag accaaaaagt
     8521 gcgtatatat atacatataa atatatattt tagatgaaga ctaactctgg gagcatttaa
     8581 cagtgttttt tgtttctgtt tttaacattt gttttcctgc tttaaaattt gcaagcattc
     8641 tcaggaattc tagggtagga agccagtttt ttgaagatgg tttatttaac catatcttat
     8701 cctagagaga tggctgtttc tttcctgtta ataaactttt acaagttcct gaaacttcag
     8761 aaagtttaaa caatttttac ttaaaaaaat gtaaaaagaa aagtctccaa acattattgt
     8821 catactgggg atcacacatt ttaaaacaca tagaaatatt ttttaaaaat tatcaattta
     8881 gcagcaacag gtaaattcat tatcttaaaa atatgggaga aggattaagc tttgtaagag
     8941 ctcgatcatg gattcttttg aaattgtgtg tagtttaatg ggagagtgtt tggtgtatat
     9001 agatgagaat gccatcactt tgttcctttc catttgagac tgaactgaaa tctcccctag
     9061 taatttttat ttttttaaag gaacccttct ccttgtcccc acaaccccag caacaaaaga
     9121 aaggaaggaa ggaagaaaca acagcttaaa aaaaaaagta atctgtaaaa tagtacagtt
     9181 ggattgctga gaatctatgt aaagagttag gaaatatagg ttaataattt ttggaacaaa
     9241 ttttaaatat aggcattact agaggaaaat tatctatgga ctgtcctatt aatgaagaat
     9301 gtctgtctta cctccgtttg ttttgggagg aggagaaaat atagaagaat ctaataagga
     9361 acaagtgatt ttactttttt agctcccagc tactgttgtg ctcgttttaa ttgctgtttt
     9421 gaagatctgc tgcttaatta tccccatccc ttagccggag atgtggagtg tttcctttca
     9481 gtttttggtg atgttgaatt cttttgtatt ccctcctggg gccaggggtc agaattccca
     9541 agcatgacca cagcttcttt taaacattaa gcttcccagt gggaaggaaa ctccagctcg
     9601 acaggtaaag ggagtgggtg gggttgctgc ctgcaatttc tctaaaaccg ctttagtgcc
     9661 ttcgtacata cacccagaca tcctgagcaa gggggacgca catgtgtgtg tgtgtggtcc
     9721 agtcactcca cagatgtaag atactcaccc ataaaggaaa ttggagtggt tctggacagg
     9781 ccccaaaggc agtgggctga atttaaaata aataaacaaa cgtcaagcaa gttaatatgc
     9841 ttatgtctca gtaatgtaga atgccaagtt ccttcctgtg tcgtgtgccc tccattactg
     9901 tgcattgatt cctccaggtg tgtaattgtg acaactgcag tgatttggaa agtctctttg
     9961 tcttgggcaa atagaagggg ttcctgttgt tctgctcttg tccttcgtct cctccccttt
    10021 tcccccagac ctcccccttc tttttgtcaa cttgctggga gctttgcttt attggttggc
    10081 agtgacctaa gaacaggata tggtgaggat gtcatggaag agaagagctc tttccgtggt
    10141 attctttggc aagagccatg tctactaaga ggttagatga cttcagtata cttataaaat
    10201 tcagtgagag tgccttcttc tcttctacca cactctggca tagatacagg cttgctggtc
    10261 acctctcatt acatagattt attttaaaaa cattttgatt atgttaattt gagctttccc
    10321 tttttttttt ttaactactt tttaaaacac ttgattacta gtggcttaga ggtgtgtaca
    10381 tctcctgaac atcacaaact tggtttctac ctaccacacg agtagccaaa agaaaagaag
    10441 cactaataga gaaaggggtg tctcacacca gacagaggac ctctgctgtc aattagatcc
    10501 agtatcatga cctaacttta agtgtggaaa agagttcaga tctctgagac actgtgaaga
    10561 aatggatggc tcatgtaaca tctctgatcc ctcagtcccc aaccctggac gtgtttcatt
    10621 tacaacattc ataggagtta acttagcagt gttgcaagtt aaggttccaa accaaattat
    10681 ttaatcagtg tccccccaat aaatcactta tccatttatt gctagttagt tttatttata
    10741 gcaacttgat ttcctatgag tatggctcct gttgtaagaa ttttcccacc tcttctgaca
    10801 tgaatgtagc ataagttagc aatcggttct tccaaactcc tgtgggttga atatggtata
    10861 gaaggtatgc aagaggaaaa agaaaggaaa agataaaact cctgcctgag aatttggaag
    10921 cacctttatt aacacatata tctcgcagaa actagaagct cataggctgt taactttttg
    10981 caactattca ctcattttta ccactttttt ttttgggtga gggggtgatt tttgtaaggt
    11041 taacagccag attccatttt gacctcagat gctgtgtact ttttaatttc attttttata
    11101 ttctgccatc ttgactcttc tctaaaacag aatgaaaatg tctgcatgct gagcaaaatg
    11161 cttacgccaa gcctgttttt ctctgcagag taaacaggat gttttcagca gacttggctc
    11221 taatagccat ctctaagatt agggaacaat tgagtcttta tgtagaaaag atccattttt
    11281 tccccatcct cagagttaaa attcaacatt taaagcttta tcggttattg ttttagattt
    11341 gagatttttg tttttaagta tctataagat ctttagaagt gagataaatt tttcgctggt
    11401 taaaaaaaat caaactttcc tctgcagtgt ttttgccaag ttttgtcaca cttcatgtgt
    11461 atgcattaac tatacttctt agtgttactg caaaaaaaaa aaacaaaaac aaaacaaaaa
    11521 aaagccttgt tctttaattg tgtttttcct cctgtgagtg gacaactaaa gccgcgtgat
    11581 gatgcggatg aaaatattct ggtctgtgtg tatacaatga attgtcagtc ttcagacctc
    11641 atggtcgtta agaaaatagg gaactcacaa accctgctgc gcactacatt tacttcttta
    11701 tctgcaagta cagggagtcc atacagtcaa gaaacacaca gatacacata atgctattga
    11761 ggacattgtc attctgtaag aaaacagaat attatctaga tttccagagt tagtgcagac
    11821 cctgtgataa cagtctgtgg gtttgtggcc agcgccaaag gtgtgtgtat tttcagaaat
    11881 ggtccctatt tgtcagtgat agtgtttttt ttttcttaag tttgacaaag ggggtggtaa
    11941 tatcacattc tttagatttg aaataattat cagctccaag aatctgtgaa catagtaata
    12001 acaataaaaa ttcaacatcg accctcccta acctgctcac catacctccc caccccatgc
    12061 ctctgaagaa agaggccatg aacctacgag gtggtaaagg gggacacagg tcagggagtg
    12121 gagagctact cctccagcag ctcagcaccc acactgcccg catgcgtgtg gccaccggga
    12181 ccagatcccg agtgattgtg gcatacccct aatatttgag tagtttttaa gctgtcagtc
    12241 tcttgtcata acctcctacc gccacccaaa aaagtaacga aagttgcagt aactgccagt
    12301 gtttgcctca ccaaatttaa atcgttccct tttcagttag ctatatacct gaatttgttt
    12361 ttaacaagaa actgtacatg gccaggaaaa atggtactac cttggccaaa gggtctttgc
    12421 aaaaagctca gtcttcagtt cttcactgtg acaaatgctt atcttgttca tgggagggga
    12481 aagatcagat aaataggcaa gaagtactct gttttaaata aagaataaat agtgtccgtt
    12541 taaagcactt tgtgcctcaa cttcattttt aaactgtaaa tcattgcttt ggaaataaat
    12601 tcccaattat aattgaccca tatctagcca atatcaacaa gttgggatgg tttttgtttt
    12661 tttctttttt ttcaaaaagg gaaattcctc tttactgctc acagtaagct gcaaaagaaa
    12721 gttgtcaagg tggcttatga tgctgttgta gcagagctgt gaaaggaagt gctttgcttt
    12781 ctctcccgcc ttccggaatc tggcgttcct tccccttcgg ctactgaaag gtgtgtacaa
    12841 ctcccagagg ggtggctgta aaagttgact ggaggcaaag tggagtggcc ttattgccag
    12901 gactagccct acagaagagc tttacagaga ggaggacagt acatcctatg tgtgttcgcc
    12961 aaaaatggga aaggtgggta tttaggcaaa acaaaataaa aacctttgga accctttaag
    13021 aagttacata ccttttaaag gtagtatagt ttctcaccaa gtgatgcatt ttagcatgac
    13081 acttcttgcc agaaattttg ggataagttg gaataaatgt gtttaaaaca tcatccaccg
    13141 ccctttttaa attttgtcta aggaattact taagtatagt atttctgaat gtgcctttgt
    13201 gagtacagag accgtccgtt ctaggaagaa gctatccgtt ggatacaaac aaacagacgg
    13261 tcagctttag tcattaggga agtcaaagtt cctcctggaa gtcccaggag cagctgttga
    13321 gatttcatta gcatcaatat tgcacagtgt agagttgagt ggaagagatt ctgggacttg
    13381 ggagaggaga caggggaagg tacccaggcg acgcagaccc acgttagtcc aagagcgcag
    13441 gtttacacat ctgcattccc tagttttctc cgtctgtatg tttgtgctca tgtggctttg
    13501 gctgttttgt tttttgtttt tctgtaagca ctggagaatt ggaatatggt gatacttgtg
    13561 acacattcat gcatgtaaac aaggcatttt ccagcttctg ccgtgtgcag agcgggcagc
    13621 acgcttttac cctttgagtc tgtgtcctga ggcggccatt acattcccac atgggcgtca
    13681 catcacgttg ctgttgatgc aaacagggta ttacacacaa ggaaaagggg ttttgaagag
    13741 ttaagattga agtgtttgag aaagaaaaga gaaaaatctg aaatcatatt ttatttcttc
    13801 agagctatta tagttgaaca cagaaatctg cagtgtcttt atttgttttt atgttttaaa
    13861 caatttcacc tcttctcccc actcctatct tctaaagaaa tatcaagcaa atgctaaggg
    13921 ccatttccat gattcctcag agctccccca aagaggagaa cagtccctcc cactcgattc
    13981 cttcagcttc attcaggaag acacagggag gagagatgct gcttctgcgc tttgctctca
    14041 ttcctctctc atggccttga aatgtattat tatgcaaatg tgaattttga tactgaattt
    14101 aagaagaggt tgttggattt tttttttttt tttttttttt ttcaaaaaaa aaagtcccac
    14161 atgtggtcat cgtcgcttct ttatgttgta aggtgaattg taactatgca ttctgcaaag
    14221 ggggtgggga ggagagggca gaaaggggaa gggagtagcg ttgcatcctt gttcttcagt
    14281 ttctgtgtcc atggtgtccc cgtgtcctgg aggggaaggg gagtgagaga cgaatgtggt
    14341 aaggtcagca cagtgagata gagacctctg agtcctcttg ccactgttgc tggcaggtct
    14401 gatggccagg taaattccag ggggcctgca gttcctgtca accaatgtgg ttcaggattc
    14461 ttgatcctag ccgtgcagtg ttaatccagt gcagcaatgg aactccacag gctccagtgt
    14521 tctctggaaa aagtactcat cctttcctga attcagagcc cttcaagctc aggaaaccac
    14581 gcttcactcg tgctgacctg aaagttaatc tttaggtcga ttttgaaaaa ctccgcctcc
    14641 tctctccttt ttaatatttc tttcttcctt tttaatcatg tttaagtgaa cttactctta
    14701 gttataagga actgtcctgc tttgtgggga agagggctgt tgcttgtcag gcaaaaaagt
    14761 tttctcttcc tacccaccat ccctctctct gcttcccttg catttggcag gctgtatgaa
    14821 gccaatgagc tgcgaggtgt tttgacaggg gaggtctgca tgcagcctct tctttgtcct
    14881 aacaattcct ttgttgatct tgcctgtgat gaatcatagc gcctgcattg ctctggtcta
    14941 ggcattattt gcaacacaca gtatcgtaag cgagagattg ttctgcctat attcagtgtt
    15001 ttccatgcag caattcttct tgttgacgtt cacagtactg taacgagtaa cagacttgat
    15061 cacagtctcc tcgtgcctgt gcagggctgc acaggcatga tcttatcagg gttccaatct
    15121 gttagattgc ctttaaacaa aaaaaacaac aaaaaaataa aatcctgacg tttcaactgt
    15181 ctcacacaaa ataatacctc gaggtacatt tccccctgca atgtaaaccc ttaactcctc
    15241 tctcctttct gacatcagtg gattatcctt tttaaaatat gaacatgtaa atagcaggat
    15301 aactttaaaa aacattttct ttgctgtgaa agtaacccta aaatatgttt tcttcttttg
    15361 tatttttttg gtttttgttt ttaagccatc agaagtttca gatctttact ctttcatgtt
    15421 taagaagaaa gagcagagga ggtcggggga gccggtttgc atttgtgttg gaggggtgtt
    15481 atctccattg cctcccacac agtgacagca gaccagtatg taaaccctgt cttggctggg
    15541 cgcggtggct cacaccagta atcccagcac tttgggaggc tgaggcaggc agatcatctg
    15601 aggtcaggag tttaagacca gcctggccaa catggtgaaa ccccgtctct actaaaaaat
    15661 tagccggacg cagtggcgcg cgcctgtggt cccagctgct cgggaggcta aggcaggaga
    15721 attgcttgaa cccgggagac ggaggttgcg gtgagccgag attgcaccac tgcactccag
    15781 tgtgggcaac agagcaagac ttcgactcaa aaacataaaa taaacaaaag acacacacac
    15841 acacaaaaac cctgtcttaa atagctgcca tctcttccag caatctagtg ccagggtaag
    15901 aagtgtctga atttctctct tccagcagat ccatcccctg cagggactcc agaatgttct
    15961 ccacacaata cctggagctc tcaacctttc ttggttcaga cacacacata cacacccctt
    16021 gagtaactca gtatcatttt gtagttcaca gaaggatgta gtccctggca ttttggtttg
    16081 cactgtagaa tccatagcct tgtcactttg ttatgctctg gaaatgtact gatttcttac
    16141 ttgggaggaa acttgtgtaa ggagatgtgc aaaccaccct gaaagccatg tgcatcctca
    16201 cctcttccat taccccctcc atgagctcga agcgacatta agtagaggga aatgctttta
    16261 acaaatgctg ctcatgtgga tctgtcagct attgcttgcc tagatttggg cacccatgaa
    16321 gcagggttgg aatggatcat tttgaattgc ttctttgcag acaccccctt cgcccccatc
    16381 tttaagataa accctttact agtcaagaag cccttttcag ttggatctca ctgatcttgt
    16441 atagtgacga cttcctttga aggaagaagc ttgattataa gtgcatgcat attatccacc
    16501 caccttctga tttgggcact gttcaccttg gaattttatt tattttgttt atctggaggc
    16561 cctttttcta tcagtctctg atccctcatg ggttctgcct gcccttgtat ctcttgtaca
    16621 atgctcccaa agggctttgc tgatctctgc acttctttcc tgggacactc cccccaccac
    16681 caccctttgc acacaccagt gaccaaagtg tatgcagtga tctcacagaa gacatcaaaa
    16741 atggtgcatg caccgtgaat gtgctcacag agacacgtgc acaagattct gcacccttgg
    16801 ccttaatctc agtatgactt aaggtgcagg aacattttta acaggtttta aaaaaacaaa
    16861 aaacccttct gggaggaaaa aaataaaaag cagatacaac agctcaactg ttcccactcc
    16921 taactctcca ctatgtgctt ataacttcac attctatgcc ctccccgcca cccacctcat
    16981 ccctgttctg cgtaaccaaa aaacagacaa caaaagcaac ctgaggagag gtttctggac
    17041 tattttatct gtctccattt agatggagat ataaatgctg ctttgggttc cataatccta
    17101 gggggctatg tttacatagt aaaatacatc ctaccaaatc aggaaacagt gaataatggg
    17161 agtcacttca cagagacgca ggaggacctg gggggcgtag cagaggagga taggtagaga
    17221 agtaccattt taattatttg tgacttgtgg cttccttcct cctctcctcc tccctccacg
    17281 tctctctttg ccccctttag acagaaggtg cagaaaaggg catcaaaaag aggctggatt
    17341 ttttaaaagg cagctttcca actttgcaca caaacaggta acaggaaggt acagcaaaaa
    17401 tcctctcatc tgaaacactg tcagcagaaa caaaacctgt aaaaatgact aatcagctgc
    17461 acatattgat gctctctgca agttaccttt aagtgttttt tttttcttat acttgaagtt
    17521 gcttttacga tattattttg gtggctttct tttctctctt tgatgggcaa tagaggaagt
    17581 agataatggg atttaaggac gcctggggga gaaaagggag gatgtggcat tgtctttttt
    17641 tttttttttt tttttttttt tagcatagag gtttaatcaa actcccatat gttgaaattg
    17701 ctcctcatat tactggtttt acatggacac agaaactagg cactttagag gtgcacttgc
    17761 atggcaggct gggccccctt ttctatattt tattttcctt tttagtatag tggtacttaa
    17821 aatcactggt tcacttaaaa aaacaaacaa taaaatgtta aactctacta atgtacaaat
    17881 aagctgaaaa gttgcatttt atgtgtattt tttgccatag caggtactgt atttctcatg
    17941 ctggatttca aaaaaaaaaa aaaaagtatc aaaaacaaaa aaaactaaag ggtggtgttt
    18001 tattggattg tgacaggttg agtaataagg aattaagtcg tcgtcatttc attaaaactg
    18061 agagatgatg taatgcatat ataagagttt tctgaagggt tttttttggg cttttaaaca
    18121 gcttattttt gtttttgttt agttttttta ttttatttta ttttggaaag atatgattgt
    18181 attatgtgca actcagttgc ttacattata actacaaaat atttttgggt tcctggaaaa
    18241 aaaagaaaaa agactaataa atgtgtttgg ctgctaagca
//
