LOCUS       NM_001080495           10839 bp    mRNA    linear   PRI 24-JUL-2024
DEFINITION  Homo sapiens trinucleotide repeat containing 18 (TNRC18), mRNA.
ACCESSION   NM_001080495 XM_376567
VERSION     NM_001080495.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 10839)
  AUTHORS   Benz,C., Ali,M., Krystkowiak,I., Simonetti,L., Sayadi,A.,
            Mihalic,F., Kliche,J., Andersson,E., Jemth,P., Davey,N.E. and
            Ivarsson,Y.
  TITLE     Proteome-scale mapping of binding sites in the unstructured regions
            of the human proteome
  JOURNAL   Mol Syst Biol 18 (1), e10584 (2022)
   PUBMED   35044719
REFERENCE   2  (bases 1 to 10839)
  AUTHORS   Zamariolli,M., Di-Battista,A., Moyses-Oliveira,M., de Mello,C.B.,
            de Paula Ramos,M.A., Liehr,T. and Melaragno,M.I.
  TITLE     Disruption of PCDH10 and TNRC18 Genes due to a Balanced
            Translocation
  JOURNAL   Cytogenet Genome Res 160 (6), 321-328 (2020)
   PUBMED   32535594
  REMARK    GeneRIF: Disruption of PCDH10 and TNRC18 Genes due to a Balanced
            Translocation.
REFERENCE   3  (bases 1 to 10839)
  AUTHORS   Brandler,W.M., Morris,A.P., Evans,D.M., Scerri,T.S., Kemp,J.P.,
            Timpson,N.J., St Pourcain,B., Smith,G.D., Ring,S.M., Stein,J.,
            Monaco,A.P., Talcott,J.B., Fisher,S.E., Webber,C. and Paracchini,S.
  TITLE     Common variants in left/right asymmetry genes and pathways are
            associated with relative hand skill
  JOURNAL   PLoS Genet 9 (9), e1003751 (2013)
   PUBMED   24068947
REFERENCE   4  (bases 1 to 10839)
  AUTHORS   Denis,N.J., Vasilescu,J., Lambert,J.P., Smith,J.C. and Figeys,D.
  TITLE     Tryptic digestion of ubiquitin standards reveals an improved
            strategy for identifying ubiquitinated proteins by mass
            spectrometry
  JOURNAL   Proteomics 7 (6), 868-874 (2007)
   PUBMED   17370265
REFERENCE   5  (bases 1 to 10839)
  AUTHORS   Margolis,R.L., Abraham,M.R., Gatchell,S.B., Li,S.H., Kidwai,A.S.,
            Breschel,T.S., Stine,O.C., Callahan,C., McInnis,M.G. and Ross,C.A.
  TITLE     cDNAs with long CAG trinucleotide repeats from human brain
  JOURNAL   Hum Genet 100 (1), 114-122 (1997)
   PUBMED   9225980
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC092171.4, BX396597.2, AC093620.3, BC029940.1, AI738451.1,
            CR993399.1, CN295035.1, DR159642.1, AB058759.1, BC131808.1,
            U80753.1, DN990416.1 and AC093376.5.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Aug 14, 2020 this sequence version replaced NM_001080495.2.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA1965299, SAMEA1966682
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000430969.6/ ENSP00000395538.1
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-288               AC092171.4         2537-2824           c
            289-418             BX396597.2         1-130
            419-442             AC092171.4         432-455             c
            443-915             BX396597.2         153-625
            916-916             AC093620.3         42677-42677         c
            917-1955            BC029940.1         305-1343
            1956-2371           AI738451.1         9-424
            2372-2372           AC093620.3         36262-36262         c
            2373-2481           AI738451.1         426-534
            2482-2996           CR993399.1         51-565
            2997-3356           CN295035.1         308-667
            3357-3436           AC093620.3         24207-24286         c
            3437-3731           AC093620.3         22363-22657         c
            3732-4450           DR159642.1         5-723
            4451-6784           AB058759.1         448-2781
            6785-7197           BC131808.1         527-939
            7198-7510           U80753.1           21-333
            7511-8036           DN990416.1         109-634
            8037-8494           AC093376.5         135370-135827       c
            8495-10839          AB058759.1         2862-5206
FEATURES             Location/Qualifiers
     source          1..10839
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
                     /map="7p22.1"
     gene            1..10839
                     /gene="TNRC18"
                     /gene_synonym="CAGL79; TNRC18A"
                     /note="trinucleotide repeat containing 18"
                     /db_xref="GeneID:84629"
                     /db_xref="HGNC:HGNC:11962"
                     /db_xref="MIM:620902"
     exon            1..394
                     /gene="TNRC18"
                     /gene_synonym="CAGL79; TNRC18A"
                     /inference="alignment:Splign:2.1.0"
     exon            395..824
                     /gene="TNRC18"
                     /gene_synonym="CAGL79; TNRC18A"
                     /inference="alignment:Splign:2.1.0"
     CDS             638..9544
                     /gene="TNRC18"
                     /gene_synonym="CAGL79; TNRC18A"
                     /note="long CAG trinucleotide repeat-containing gene 79
                     protein"
                     /codon_start=1
                     /product="trinucleotide repeat-containing gene 18 protein"
                     /protein_id="NP_001073964.2"
                     /db_xref="CCDS:CCDS47534.1"
                     /db_xref="GeneID:84629"
                     /db_xref="HGNC:HGNC:11962"
                     /db_xref="MIM:620902"
                     /translation="MDGRDFGPQRSVHGPPPPLLSGLAMDSHRVGAATAGRLPASGLP
                     GPLPPGKYMAGLNLHPHPGEAFLGSFVASGMGPSASSHGSPVPLPSDLSFRSPTPSNL
                     PMVQLWAAHAHEGFSHLPSGLYPSYLHLNHLEPPSSGSPLLSQLGQPSIFDTQKGQGP
                     GGDGFYLPTAGAPGSLHSHAPSARTPGGGHSSGAPAKGSSSRDGPAKERAGRGGEPPP
                     LFGKKDPRARGEEASGPRGVVDLTQEARAEGRQDRGPPRLAERLSPFLAESKTKNAAL
                     QPSVLTMCNGGAGDVGLPALVAEAGRGGAKEAARQDEGARLLRRTETLLPGPRPCPSP
                     LPPPPAPPKGPPAPPAATPAGVYTVFREQGREHRVVAPTFVPSVEAFDERPGPIQIAS
                     QARDARAREREAGRPGVLQAPPGSPRPLDRPEGLREKNSVIRSLKRPPPADAPTVRAT
                     RASPDPRAYVPAKELLKPEADPRPCERAPRGPAGPAAQQAAKLFGLEPGRPPPTGPEH
                     KWKPFELGNFAATQMAVLAAQHHHSRAEEEAAVVAASSSKKAYLDPGAVLPRSAATCG
                     RPVADMHSAAHGSGEASAMQSLIKYSGSFARDAVAVRPGGCGKKSPFGGLGTMKPEPA
                     PTSAGASRAQARLPHSGGPAAGGGRQLKRDPERPESAKAFGREGSGAQGEAEVRHPPV
                     GIAVAVARQKDSGGSGRLGPGLVDQERSLSLSNVKGHGRADEDCVDDRARHREERLLG
                     ARLDRDQEKLLRESKELADLARLHPTSCAPNGLNPNLMVTGGPALAGSGRWSADPAAH
                     LATHPWLPRSGNASMWLAGHPYGLGPPSLHQGMAPAFPPGLGGSLPSAYQFVRDPQSG
                     QLVVIPSDHLPHFAELMERATVPPLWPALYPPGRSPLHHAQQLQLFSQQHFLRQQEFL
                     YLQQQAAQALELQRSAQLVQERLKAQEHRAEMEEKGSKRGLEAAGKAGLATAGPGLLP
                     RKPPGLAAGPAGTYGKAVSPPPSPRASPVAALKAKVIQKLEDVSKPPAYAYPATPSSH
                     PTSPPPASPPPTPGITRKEEAPENVVEKKDLELEKEAPSPFQALFSDIPPRYPFQALP
                     PHYGRPYPFLLQPTAAADADGLAPDVPLPADGPERLALSPEDKPIRLSPSKITEPLRE
                     GPEEEPLAEREVKAEVEDMDEGPTELPPLESPLPLPAAEAMATPSPAGGCGGGLLEAQ
                     ALSATGQSCAEPSECPDFVEGPEPRVDSPGRTEPCTAALDLGVQLTPETLVEAKEEPV
                     EVPVAVPVVEAVPEEGLAQVAPSESQPTLEMSDCDVPAGEGQCPSLEPQEAVPVLGST
                     CFLEEASSDQFLPSLEDPLAGMNALAAAAELPQARPLPSPGAAGAQALEKLEAAESLV
                     LEQSFLHGITLLSEIAELELERRSQEMGGAERALVARPSLESLLAAGSHMLREVLDGP
                     VVDPLKNLRLPRELKPNKKYSWMRKKEERMYAMKSSLEDMDALELDFRMRLAEVQRQY
                     KEKQRELVKLQRRRDSEDRREEPHRSLARRGPGRPRKRTHAPSALSPPRKRGKSGHSS
                     GKLSSKSLLTSDDYELGAGIRKRHKGSEEEHDALIGMGKARGRNQTWDEHEASSDFIS
                     QLKIKKKKMASDQEQLASKLDKALSLTKQDKLKSPFKFSDSAGGKSKTSGGCGRYLTP
                     YDSLLGKNRKALAKGLGLSLKSSREGKHKRAAKTRKMEVGFKARGQPKSAHSPFASEV
                     SSYSYNTDSEEDEEFLKDEWPAQGPSSSKLTPSLLCSMVAKNSKAAGGPKLTKRGLAA
                     PRTLKPKPATSRKQPFCLLLREAEARSSFSDSSEESFDQDESSEEEDEEEELEEEDEA
                     SGGGYRLGARERALSPGLEESGLGLLARFAASALPSPTVGPSLSVVQLEAKQKARKKE
                     ERQSLLGTEFEYTDSESEVKVRKRSPAGLLRPKKGLGEPGPSLAAPTPGARGPDPSSP
                     DKAKLAVEKGRKARKLRGPKEPGFEAGPEASDDDLWTRRRSERIFLHDASAAAPAPVS
                     TAPATKTSRCAKGGPLSPRKDAGRAKDRKDPRKKKKGKEAGPGAGLPPPRAPALPSEA
                     RAPHASSLTAAKRSKAKAKGKEVKKENRGKGGAVSKLMESMAAEEDFEPNQDSSFSED
                     EHLPRGGAVERPLTPAPRSCIIDKDELKDGLRVLIPMDDKLLYAGHVQTVHSPDIYRV
                     VVEGERGNRPHIYCLEQLLQEAIIDVRPASTRFLPQGTRIAAYWSQQYRCLYPGTVVR
                     GLLDLEDDGDLITVEFDDGDTGRIPLSHIRLLPPDYKIQCAEPSPALLVPSAKRRSRK
                     TSKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKAKGDRAATLEEGNPTDEVPSTPLAL
                     EPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPFAELPAPATSL
                     APAPLITMPATRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEA
                     LLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDS
                     GNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCG
                     TGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS
                     SSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARP
                     SAHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAKSRPKKREGVHLPTTKELAKRQRLP
                     SVENRPKIAAFLPARQLWKWFGKPTQRRGMKGKARKLFYKAIVRGKEMIRIGDCAVFL
                     SAGRPNLPYIGRIQSMWESWGNNMVVRVKWFYHPEETSPGKQFHQGQHWDQKSSRSLP
                     AALRVSSQRKDFMERALYQSSHVDENDVQTVSHKCLVVGLEQYEQMLKTKKYQDSEGL
                     YYLAGTYEPTTGMIFSTDGVPVLC"
     exon            825..980
                     /gene="TNRC18"
                     /gene_synonym="CAGL79; TNRC18A"
                     /inference="alignment:Splign:2.1.0"
     exon            981..1124
                     /gene="TNRC18"
                     /gene_synonym="CAGL79; TNRC18A"
                     /inference="alignment:Splign:2.1.0"
     exon            1125..2789
                     /gene="TNRC18"
                     /gene_synonym="CAGL79; TNRC18A"
                     /inference="alignment:Splign:2.1.0"
     exon            2790..2892
                     /gene="TNRC18"
                     /gene_synonym="CAGL79; TNRC18A"
                     /inference="alignment:Splign:2.1.0"
     exon            2893..3098
                     /gene="TNRC18"
                     /gene_synonym="CAGL79; TNRC18A"
                     /inference="alignment:Splign:2.1.0"
     exon            3099..3245
                     /gene="TNRC18"
                     /gene_synonym="CAGL79; TNRC18A"
                     /inference="alignment:Splign:2.1.0"
     exon            3246..3436
                     /gene="TNRC18"
                     /gene_synonym="CAGL79; TNRC18A"
                     /inference="alignment:Splign:2.1.0"
     exon            3437..3866
                     /gene="TNRC18"
                     /gene_synonym="CAGL79; TNRC18A"
                     /inference="alignment:Splign:2.1.0"
     exon            3867..4856
                     /gene="TNRC18"
                     /gene_synonym="CAGL79; TNRC18A"
                     /inference="alignment:Splign:2.1.0"
     exon            4857..5032
                     /gene="TNRC18"
                     /gene_synonym="CAGL79; TNRC18A"
                     /inference="alignment:Splign:2.1.0"
     exon            5033..5169
                     /gene="TNRC18"
                     /gene_synonym="CAGL79; TNRC18A"
                     /inference="alignment:Splign:2.1.0"
     exon            5170..5298
                     /gene="TNRC18"
                     /gene_synonym="CAGL79; TNRC18A"
                     /inference="alignment:Splign:2.1.0"
     exon            5299..5470
                     /gene="TNRC18"
                     /gene_synonym="CAGL79; TNRC18A"
                     /inference="alignment:Splign:2.1.0"
     exon            5471..5831
                     /gene="TNRC18"
                     /gene_synonym="CAGL79; TNRC18A"
                     /inference="alignment:Splign:2.1.0"
     exon            5832..6107
                     /gene="TNRC18"
                     /gene_synonym="CAGL79; TNRC18A"
                     /inference="alignment:Splign:2.1.0"
     exon            6108..6356
                     /gene="TNRC18"
                     /gene_synonym="CAGL79; TNRC18A"
                     /inference="alignment:Splign:2.1.0"
     exon            6357..6784
                     /gene="TNRC18"
                     /gene_synonym="CAGL79; TNRC18A"
                     /inference="alignment:Splign:2.1.0"
     exon            6785..6937
                     /gene="TNRC18"
                     /gene_synonym="CAGL79; TNRC18A"
                     /inference="alignment:Splign:2.1.0"
     exon            6938..7079
                     /gene="TNRC18"
                     /gene_synonym="CAGL79; TNRC18A"
                     /inference="alignment:Splign:2.1.0"
     exon            7080..7197
                     /gene="TNRC18"
                     /gene_synonym="CAGL79; TNRC18A"
                     /inference="alignment:Splign:2.1.0"
     exon            7198..7273
                     /gene="TNRC18"
                     /gene_synonym="CAGL79; TNRC18A"
                     /inference="alignment:Splign:2.1.0"
     exon            7274..7382
                     /gene="TNRC18"
                     /gene_synonym="CAGL79; TNRC18A"
                     /inference="alignment:Splign:2.1.0"
     exon            7383..7499
                     /gene="TNRC18"
                     /gene_synonym="CAGL79; TNRC18A"
                     /inference="alignment:Splign:2.1.0"
     exon            7500..7664
                     /gene="TNRC18"
                     /gene_synonym="CAGL79; TNRC18A"
                     /inference="alignment:Splign:2.1.0"
     exon            7665..9025
                     /gene="TNRC18"
                     /gene_synonym="CAGL79; TNRC18A"
                     /inference="alignment:Splign:2.1.0"
     exon            9026..9262
                     /gene="TNRC18"
                     /gene_synonym="CAGL79; TNRC18A"
                     /inference="alignment:Splign:2.1.0"
     exon            9263..9337
                     /gene="TNRC18"
                     /gene_synonym="CAGL79; TNRC18A"
                     /inference="alignment:Splign:2.1.0"
     exon            9338..10839
                     /gene="TNRC18"
                     /gene_synonym="CAGL79; TNRC18A"
                     /inference="alignment:Splign:2.1.0"
     regulatory      10823..10828
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TNRC18"
                     /gene_synonym="CAGL79; TNRC18A"
                     /note="hexamer: CATAAA"
     polyA_site      10839
                     /gene="TNRC18"
                     /gene_synonym="CAGL79; TNRC18A"
                     /note="major polyA site"
ORIGIN      
        1 agatcctgcg agaggaactt gaaagggggg ttgtgtaatg taccttttcc aatcccgggc
       61 tgtatatgga gatttgggat tctttaaacc ggcgctacct ggattttatt aaaaagcggg
      121 gagctcggcg ggaggaaagc tggcttttcc gggggctgcg ggagccgggc cgcgggaggg
      181 cggaggagtt ggcgcgccga gcgctcggcc cggggagcgg ttttctacca aaaaaaggaa
      241 aggcgggcaa aaagtgtgag gcggctgcgg gtggcggagg ggagcggcgg ccgcgggatg
      301 gcgggcagca ggggcgccta gctgcgccgg gagccggggc cgccgccgga gtcgttgtcg
      361 ccggagcctg gagccgtgaa cccagccgcg ccagacgccg tgtgcgccgc ctcgcgcagc
      421 tccgcctggc cgcccggagg ggccccaccg ccggccgcct gtgcgccccg ggccgcgggc
      481 ccgccgccga gcgcaagccc cgctggccgc cgccatgcac gccgcggagc ccccgccgcc
      541 cgaggactct gggactacgc cgaggccgaa cttttaggtc ccactgagct aggcctgcgg
      601 gccgggtggg gggctgatcg cggcactccc gcggaggatg gatggccgag acttcgggcc
      661 ccagcggtcc gtgcacggtc ccccgccgcc gctgctgtcc ggcctggcca tggacagcca
      721 ccgcgtgggc gcggccactg ccggacgctt gcccgcctcg ggcttgcccg gcccgctgcc
      781 gcccgggaag tacatggccg gcctgaatct ccatccgcac ccgggcgagg ccttcttggg
      841 cagctttgtg gccagcggga tggggccctc ggcctcgtcc catgggagcc cagtgccact
      901 gccctctgac ctgtctttcc gctccccaac ccctagcaac ctgcccatgg tgcagctgtg
      961 ggccgcccac gcccatgaag gcttctccca cctgcccagt gggctgtacc catcctacct
     1021 ccacctgaac cacctggagc cccccagcag tgggagcccc ctcctcagcc agctgggtca
     1081 gcccagcatt ttcgataccc agaaaggtca ggggccagga ggagacggtt tctacctgcc
     1141 caccgcgggg gctccgggct ccctgcactc tcacgcgccc tcggcccgga cccctggcgg
     1201 cggccactcc tcgggcgccc cggccaaagg ctcgtcgtcg cgggacggtc cagccaagga
     1261 gcgggcgggc cgcggcgggg agccgcctcc gcttttcggc aagaaggacc cgcgcgcccg
     1321 gggcgaggag gcctcggggc cacggggcgt ggtggacctg acccaggagg cgcgcgccga
     1381 gggccgccag gaccgggggc ccccgcgcct ggctgagcgc ctgtcgccct tcctggctga
     1441 gtccaagacc aagaatgcgg cgctgcagcc gtcggtactg accatgtgca acggcggcgc
     1501 cggggacgtg gggctgcccg cgctggtggc cgaagcgggg cgcgggggtg ccaaggaggc
     1561 tgcccggcag gacgagggcg cgcggctgct gcggcgcacg gagaccctgc tccctgggcc
     1621 gcgcccctgc ccctcaccgc tgcccccgcc gcccgcgccc cccaaggggc ctcctgcacc
     1681 ccccgcggcc acccccgccg gcgtctacac cgtcttccgc gagcagggcc gtgagcaccg
     1741 cgtggtggcg cccaccttcg tgccttccgt ggaggccttc gacgagcgcc cggggcccat
     1801 ccagatcgca tcccaggcgc gcgatgcccg ggcccgcgag cgcgaggctg gcaggccagg
     1861 ggtcctgcag gcgccccccg gctccccgcg gcctctggac cggcccgagg gcctgcgcga
     1921 gaagaactcg gtcatccgct cgctcaagcg gccgcccccc gcggatgccc ccacggtgcg
     1981 ggccacacgc gcctccccgg acccccgcgc ctacgtgcct gccaaggagc tgctcaagcc
     2041 cgaggcggac ccgaggccct gcgagcgtgc gccccgcggc ccagccggtc ctgcagccca
     2101 acaggccgcc aagctcttcg gcctggagcc cgggcgcccc ccgcccaccg gccctgagca
     2161 taaatggaaa cccttcgagc tgggcaactt cgccgccacg cagatggccg tgctggccgc
     2221 gcagcaccac cacagccgcg ccgaagagga ggccgccgtg gtcgctgcct cctcctccaa
     2281 gaaggcctac ctggaccctg gggctgtgct gccccgctcg gcggccacct gcggccggcc
     2341 ggtcgctgac atgcactctg cggcccacgg gtctggagag gcctcggcca tgcagagcct
     2401 tataaagtac agtggcagct ttgcccggga cgccgtggcc gtgcgccctg gtggctgtgg
     2461 caagaagagc ccctttggag gtttgggcac catgaaaccc gagcctgcgc ccacctctgc
     2521 gggtgcctcc cgagcccagg cccgtctccc acactccgga ggccctgcag cgggcggcgg
     2581 ccggcagctg aagcgggacc ccgagaggcc cgagagcgcc aaagctttcg ggcgcgaggg
     2641 ctctggtgcc cagggtgagg cagaagtgcg acacccgcct gtgggcattg cagtggctgt
     2701 ggcccggcag aaggacagtg gcggcagtgg ccggctgggg cctgggctgg tagaccagga
     2761 gcgctctctg tcgctgagta acgtcaaagg gcacggccga gcagatgagg actgtgtgga
     2821 cgaccgggcc agacaccggg aggaacggct gctcggggca cggctggacc gggatcagga
     2881 gaagctgctc agagagagta aggagctggc tgacctggcc cgcctgcacc ctaccagctg
     2941 tgctcctaac ggcctgaacc ccaacctcat ggtgacgggg ggcccggcgc tggcgggctc
     3001 aggtcgctgg tctgccgacc ccgcagccca tctggccacg cacccctggt tgccccgctc
     3061 gggcaacgca tccatgtggc tcgctggaca cccctacggc ttgggtcccc catctctgca
     3121 ccagggcatg gcccctgcgt tcccacctgg cctggggggc tccctcccgt cagcctacca
     3181 gtttgtcagg gacccccaat cgggccagct ggtggtcatt cccagtgatc accttcctca
     3241 ctttgcggag ctgatggagc gggccaccgt accgcccctc tggcccgccc tgtacccgcc
     3301 gggccgcagc cccctgcacc acgcccagca gctgcagctc ttctcacagc agcacttcct
     3361 gcggcagcag gagttcctgt acctgcagca gcaggcggcc caggccttgg aactgcagag
     3421 gagcgcccag ctcgtgcagg agcggttgaa ggcgcaggag caccgggcgg agatggaaga
     3481 gaaggggagc aagcggggcc tggaggctgc gggcaaggct ggcctggcca ccgccggccc
     3541 cgggctgctg ccgcggaagc cccctggcct ggccgccggc cccgcgggca cctacggcaa
     3601 ggccgtgagc ccgccaccat caccccgcgc atcccctgtg gctgccctga aggccaaggt
     3661 catccagaag ctggaggacg tgtccaagcc acccgcctac gcctaccccg ccacccccag
     3721 ctcccacccc accagcccgc cgcccgcctc cccaccgccc accccgggta tcacccgcaa
     3781 ggaggaggct cccgagaatg tggtcgagaa gaaagacttg gagttggaga aggaagcccc
     3841 cagccccttc caggccctgt tctcagatat cccgcccagg tacccgttcc aagccctgcc
     3901 accgcactac gggaggccct accctttcct gctgcagccc acggccgccg ccgacgcgga
     3961 cggcttggcc cctgatgtgc cgctcccggc tgatgggccc gagcgcctgg cactctcacc
     4021 cgaagacaag cccatccgct tgtccccctc caagatcaca gagccgctgc gggagggccc
     4081 ggaggaagaa ccgctggctg agcgggaggt gaaggcagag gtggaggaca tggacgaggg
     4141 ccccacagag ctgccgcctc tggagtcgcc gctgccactg cccgccgcgg aagccatggc
     4201 tacccccagc cctgcagggg gttgtggagg tggcctgttg gaggcccagg cgctgagtgc
     4261 caccgggcag agctgcgcag agccctctga gtgtccagac tttgtggagg ggcctgaacc
     4321 acgggtggat tccccgggcc ggacagaacc ctgcaccgcc gccctggacc tgggggtgca
     4381 gctgacaccc gagacactgg tggaggccaa ggaggagccg gtggaggtgc ctgtggcggt
     4441 gcccgtggtg gaggcagtgc ccgaggaagg cctggcgcag gtggcaccga gcgagtccca
     4501 gcccacccta gaaatgtcag actgtgacgt gcccgccggg gagggacagt gcccgagcct
     4561 ggagccccaa gaggccgtgc ctgtactcgg cagcacctgc ttcctggaag aggcaagctc
     4621 tgaccagttc ctgcccagtc tggaggaccc actggctggc atgaacgccc tggcggcagc
     4681 tgcggagctg ccccaggcca ggcctctgcc ctccccgggt gctgctggag cccaggcctt
     4741 ggagaagctg gaagcagccg agagccttgt cttggagcag agcttcctgc atggcatcac
     4801 cctgctaagt gagatcgcag agctggagct ggagaggagg agccaagaga tgggaggtgc
     4861 ggagcgggcc ctggtggcgc ggccctccct ggagagtctg ctggcagctg gcagccacat
     4921 gctgagggag gtgctggatg ggcccgtggt ggacccactc aagaacctgc ggctcccgcg
     4981 ggagctgaag cccaacaaga agtacagctg gatgcgcaag aaggaggagc ggatgtatgc
     5041 catgaagtcc tccctggagg acatggacgc cctggagctg gacttccgga tgcggctggc
     5101 cgaggtgcag cgccagtaca aggagaagca gcgtgagctg gtgaagctgc agcgccgccg
     5161 ggactccgag gacaggcgcg aggaacccca tagaagcttg gcacgcagag gccctggcag
     5221 gccgcggaaa cggacccacg ccccgagcgc cctgtcgccc ccccgcaaga gagggaagag
     5281 cggccacagt agcggaaagc tgagcagcaa gtctctgctg acatcagatg attatgagct
     5341 gggagcaggg ataagaaaga gacacaaggg gtctgaggag gaacatgatg ccctcatcgg
     5401 aatggggaaa gccaggggga ggaaccagac ttgggatgaa catgaggcct cgtcggactt
     5461 catcagtcag ctaaagatta agaagaagaa gatggccagc gaccaggagc agttggcaag
     5521 caagctcgac aaggccctct ccctcaccaa gcaggacaag ttgaagtcgc ccttcaagtt
     5581 ttcggacagt gctgggggga aatcgaaaac tagcgggggc tgcggcaggt acttgactcc
     5641 ttacgacagc ctgctgggga agaacaggaa ggcgctggcc aagggcctcg gcctgtctct
     5701 gaaatcctcc agagaaggta aacacaaaag ggcagccaaa accaggaaga tggaggtggg
     5761 gttcaaggcc agaggccagc ccaagtcggc ccattccccg tttgcctcgg aagtgagcag
     5821 ctactcttac aatacggact cagaggaaga cgaagaattc ctgaaggacg agtggcccgc
     5881 ccaaggcccc tccagctcca aactgacgcc ttccctcctg tgtagcatgg tggcaaagaa
     5941 cagcaaggca gctggtggcc ccaagctgac caagaggggc ctggcggccc cccggactct
     6001 gaaacccaag ccggccacca gcaggaagca gccgttttgt ctgctgcttc gagaggccga
     6061 ggcgcgttcc tccttcagcg actcttcgga ggaatcgttt gaccaagatg agagctcgga
     6121 ggaggaggac gaggaggagg agctcgagga ggaggacgag gccagcggtg gtggctacag
     6181 gctgggtgcc cgggagcggg ccctgtcacc gggcctggag gagagtgggc tgggcctgct
     6241 ggcacgcttc gccgccagcg ccctccccag ccccacggtg ggtccatccc tgtctgtggt
     6301 acagctggag gccaagcaga aggcccggaa gaaagaggag cggcagagcc tgctgggcac
     6361 agagttcgag tacaccgact cagagagcga ggtcaaggtg cgcaagcggt cgcctgcggg
     6421 gctgctgcgg cccaagaagg ggctggggga gccgggaccc tccctggccg cacccacgcc
     6481 tggcgcccgc ggtcccgacc ccagcagccc agacaaggcc aagctggcgg tggagaaggg
     6541 gcgcaaggcc cggaagctgc ggggccccaa ggagcctggc ttcgaggcgg ggcccgaggc
     6601 cagcgacgac gacctgtgga cgcggcgccg cagcgagcgc atcttcctgc acgacgcctc
     6661 ggctgctgca cctgcgcccg tcagcaccgc gcccgccacc aagaccagcc gctgcgccaa
     6721 gggcggcccc ctgagcccgc gcaaggacgc cgggcgtgca aaggacagga aggaccccag
     6781 gaagaagaag aaagggaaag aggctgggcc aggagctggg ctgccgccgc cccgagctcc
     6841 tgccttgccc tctgaggcca gggctcctca cgccagctcc ctgaccgctg ccaaaaggag
     6901 caaagccaag gccaaaggga aggaggtgaa gaaggagaac cgcggcaagg ggggtgccgt
     6961 gagcaagctg atggagagca tggcagccga ggaggacttt gaacccaacc aagactcgag
     7021 cttctctgag gacgagcacc tgccgcgtgg cggggctgtg gagcggccgc tgaccccggc
     7081 ccctcgctcc tgcatcatcg acaaggatga gctgaaggac ggcctgcgtg tgctcatccc
     7141 catggatgac aagctgctgt acgccgggca cgtgcagacc gtgcactcgc cagacatata
     7201 ccgcgtggtg gtggagggtg agcggggcaa ccggccccac atctactgtc tggagcagtt
     7261 gctgcaggag gcgatcatcg atgtgaggcc agcctccact cgcttcttgc cacaagggac
     7321 caggattgca gcctactgga gccagcagta ccgctgtctc tacccaggca ctgtggtccg
     7381 agggttactg gacctggagg acgatgggga cttgatcacc gtggagtttg acgacggaga
     7441 cacgggcagg atccccctct cacatatccg cctcctgccc cctgactata agatacagtg
     7501 tgctgagccg tccccggccc ttctggtgcc aagtgccaag cgccgcagcc ggaagaccag
     7561 caaagacact ggggagggca aagatggtgg cacggctggg tcggaggagc caggagccaa
     7621 ggcccgtggg cgtgggcgga aacccagcgc caaggccaag ggtgacagag ccgctaccct
     7681 ggaggagggg aacccaacag acgaggtccc cagtaccccc ttagccctgg agccgagcag
     7741 caccccaggt tccaagaaga gccccccaga gcctgtggac aagcgagcca aggcccccaa
     7801 ggcgcgcccg gcaccgccgc agcccagtcc cgcaccaccc gccttcacca gctgcccagc
     7861 acccgagcca tttgcagagc tgccagctcc tgccacctcc ctggccccag cacccctcat
     7921 caccatgcct gccacacgcc ccaagcccaa gaaggcgcgg gcagccgagg agtcgggtgc
     7981 caagggccct cggaggccgg gggaggaggc cgagctgctt gtcaaactgg accacgaggg
     8041 tgtcacgtca cccaaaagca agaaggctaa agaggccctg ctgctccggg aggatccggg
     8101 ggcggggggc tggcaggagc ccaagagcct cctgagcctg ggcagctatc cccccgcggc
     8161 cggcagcagc gagcccaagg caccctggcc caaggccacc gacggggacc tcgcccagga
     8221 gcccgggccg gggctcacgt tcgaggactc tgggaacccc aagagcccag acaaggccca
     8281 ggctgagcag gacggggccg aagagtccga gagcagcagc agcagcagta gtggcagcag
     8341 tagcagcagc agcagcagca gcagcagcgg ctcggagaca gaaggggagg aggaaggcga
     8401 caagaacggg gacgggggct gcggcaccgg gggccgtaac tgcagcgctg ccagctccag
     8461 ggcggcctca ccggcctcct cctcctcctc ctcatcctcc tcctcctcct cctcctcctc
     8521 ctcatcctcc tcttcctcct cctcctcttc ctcctcctcc tcttcctctt cgtcttcctc
     8581 ctcttcctcc tcctcctctt cctcgtcctc atcctcctcc tcctcctcct cttcctcctc
     8641 ttcttcctcc accacagacg aggactcttc ctgcagctcg gacgatgagg cagcccccgc
     8701 ccccacggct ggcccttccg cgcaggcggc gctccccacc aaggccacca agcaggccgg
     8761 caaggcgcgg ccctcggccc actccccagg caagaagacg cccgcgcccc agccccaggc
     8821 gcctcctccg cagcccacac agcctctgca gcccaaggct caggccgggg ccaagagccg
     8881 acccaagaag agagagggcg tccacctccc caccaccaag gagctggcca agcggcagcg
     8941 cctgccgtcc gtggagaacc ggcccaagat cgccgccttc ctgccagccc ggcagctctg
     9001 gaagtggttc ggcaagccca cccagcggcg tggcatgaag ggcaaggccc gcaagctctt
     9061 ctacaaggcc atcgtgcgcg gcaaggagat gatccgtatc ggggactgtg ccgtgttcct
     9121 ctctgccggc cgccccaacc tgccctacat cggccgcatc cagagcatgt gggagtcgtg
     9181 gggcaacaac atggtggtcc gcgtcaagtg gttctaccac cccgaggaga ccagcccggg
     9241 caagcagttc caccagggcc agcactggga ccagaagtcc agccgcagcc tcccggcggc
     9301 cctgcgggtc tccagccaga ggaaggactt catggagcgc gcgctatacc agtcctcgca
     9361 tgtggacgaa aatgacgtgc agacggtgtc gcacaagtgc ctggtggtgg gcctggagca
     9421 gtatgagcag atgctgaaga ccaagaagta ccaggacagc gagggcctgt actacctcgc
     9481 gggcacctac gagcccacca cgggcatgat cttctccacg gacggcgtgc ccgtgctctg
     9541 ctgagcccgc cgggccctgc gggccacctg tgccccgagg gcggccaggg acccatctcc
     9601 atcactgcca tggcgcggag accacgtgcg ttgtgtgcat gcgagcgctc ctgcaggcgt
     9661 gtgcatgggg ccaggtgtgc acgtggatgc ccgggtgagt gtgtgtgcat gcacgtgtgt
     9721 gcacgcatgt gcacatgcct ccagccccac cttccaaccc ctcagtgccc ccaggacagg
     9781 ggcccctctt agctatcagg gtatggccgg accggccctt cctgcccagc acgttgcaag
     9841 cacttggcca ggccggccct ccaggctgct gctgcgtggg ggcccgggtg cccccaggtc
     9901 catgcagact ggggattcgg tggggagggg cgcttctaag gaaccaaact gacgctcact
     9961 ctgggcttcc caagcaccct tagcatggag cccaccccaa ggcctcccac cgtgcatggg
    10021 acagggcagc ccgatgccag ctggcctacc tgactgtgcc aggggccctg cccccaccct
    10081 ctcaggatgg cctagacttg gggaacagag ccgggtgggg ttgcagcccg gagtgtctgt
    10141 caaaggcacc aggtggagag ggcccggcac aggcccaccc tggtccaaac cctcacacta
    10201 cagaaaaccc caatggtgct gaaactgtcg cccggccacg cctggcccct ccccacccag
    10261 gagggaggtg gcacttctta acctgtacag ttttattgta ccaagagact cgccccgccc
    10321 ctgtatcata agcctttaaa tggagtcaac tttttaatta tatatataaa gataaatata
    10381 tataaatata tatataaact ttttaaaact gtgaaaaata gctatgaaat tataaaaaaa
    10441 aacattctga cgtgcagaat attatttttt atttcctgtt agattatagt gtctagcacc
    10501 ggcttcaccg gcctcccagt ccccagcaca ccccccgccc accccaccaa gtgtactgta
    10561 ctcacccccc aggatagaga agtgtttgtt agggagagaa gagggagagg caggagccgg
    10621 cccaagccca gggtccctgc ttgggcccca gaaagcactt aaccaggccc caagccttca
    10681 agggaaacca aggcctcaac cagacaatct tgagggaagg aaaagccaga ctttgggttt
    10741 gttttttggg ggaattattg gttttttttt ttatgtttct tttggaattt tgtttgttgg
    10801 caaattctgt gtgatctttt ttcataaaaa aaaagaaaa
//
