LOCUS       XM_047417168            8410 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens transportin 1 (TNPO1), transcript variant
            X3, mRNA.
ACCESSION   XM_047417168
VERSION     XM_047417168.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000005.10) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8410
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="5"
     gene            1..8410
                     /gene="TNPO1"
                     /gene_synonym="IPO2; KPNB2; MIP; MIP1; TRN"
                     /note="transportin 1; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 2 mRNAs, 81 ESTs, 3416
                     long SRA reads, 3 Proteins, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     100 samples with support for all annotated introns"
                     /db_xref="GeneID:3842"
                     /db_xref="HGNC:HGNC:6401"
                     /db_xref="MIM:602901"
     CDS             119..2695
                     /gene="TNPO1"
                     /gene_synonym="IPO2; KPNB2; MIP; MIP1; TRN"
                     /codon_start=1
                     /product="transportin-1 isoform X3"
                     /protein_id="XP_047273124.1"
                     /db_xref="GeneID:3842"
                     /db_xref="HGNC:HGNC:6401"
                     /db_xref="MIM:602901"
                     /translation="MEYEWKPDEQGLQQILQLLKESQSPDTTIQRTVQQKLEQLNQYP
                     DFNNYLIFVLTKLKSEDEPTRSLSGLILKNNVKAHFQNFPNGVTDFIKSECLNNIGDS
                     SPLIRATVGILITTIASKGELQNWPDLLPKLCSLLDSEDYNTCEGAFGALQKICEDSA
                     EILDSDVLDRPLNIMIPKFLQFFKHSSPKIRSHAVACVNQFIISRTQALMLHIDSFIE
                     NLFALAGDEEPEVRKNVCRALVMLLEVRMDRLLPHMHNIVEYMLQRTQDQDENVALEA
                     CEFWLTLAEQPICKDVLVRHLPKLIPVLVNGMKYSDIDIILLKGDVEEDETIPDSEQD
                     IRPRFHRSRTVAQQHDEDGIEEEDDDDDEIDDDDTISDWNLRKCSAAALDVLANVYRD
                     ELLPHILPLLKELLFHHEWVVKESGILVLGAIAEGCMQGMIPYLPELIPHLIQCLSDK
                     KALVRSITCWTLSRYAHWVVSQPPDTYLKPLMTELLKRILDSNKRVQEAACSAFATLE
                     EEACTELVPYLAYILDTLVFAFSKYQHKNLLILYDAIGTLADSVGHHLNKPEYIQMLM
                     PPLIQKWNMLKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVNLVQKTLAQAM
                     LNNAQPDQYEAPDKDFMIVALDLLSGLAEGLGGNIEQLVARSNILTLMYQCMQDKMPE
                     VRQSSFALLGDLTKACFQHVKPCIADFMPILGTNLNPEFISVCNNATWAIGEISIQMA
                     ITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICTMISVNPSGVIQ
                     DFIFFCDAVASWINPKDDLRDMFCKILHGFKNQVGDENWRRFSDQFPLPLKERLAAFY
                     GV"
ORIGIN      
        1 ccttgcgctc ggcggccgcg gcggcagcag cagcagacgc tggcggccgg gctgccagga
       61 gcagttccgc cgggtttcac tgtccgtgac ttccttcggg gcacctcagc aaaccaagat
      121 ggagtatgag tggaaacctg acgagcaagg gcttcagcaa atcctgcagc tgttgaagga
      181 gtcccagtcc ccagacacca ccatccagag aaccgtgcaa caaaaactgg aacaacttaa
      241 tcagtatcca gactttaaca actacttgat ttttgttctt acaaaattaa aatctgaaga
      301 tgaacccaca agatcattga gtggtcttat cttgaagaat aatgtgaaag cacactttca
      361 gaacttccca aatggtgtaa cagactttat taaaagtgaa tgtttaaata atattggtga
      421 ctcctctcct ctgattagag ccactgttgg tattttgatc acaactatag cctccaaggg
      481 agaattgcag aattggcctg acctcttacc aaaactctgt agcctgttgg attctgaaga
      541 ttataatacc tgtgagggag catttggtgc ccttcagaag atttgtgaag attctgctga
      601 gattttagac agtgatgttt tagatcgtcc tctcaacatc atgattccca aatttttaca
      661 gttcttcaag catagtagtc caaaaataag gtctcacgct gttgcatgtg tcaatcagtt
      721 tatcatcagt aggactcaag ctctaatgtt gcacattgat tcttttattg agaatctctt
      781 tgcattagct ggtgatgaag aaccagaggt acggaaaaat gtgtgccgag cacttgtgat
      841 gttgctcgaa gttcgaatgg atcgcctgct tcctcacatg cataatatag ttgagtacat
      901 gctacagagg actcaagatc aagatgaaaa tgtggcttta gaagcctgtg aattttggct
      961 aactttagct gaacagccaa tatgcaaaga tgtactcgta aggcatcttc ctaagttgat
     1021 tcctgtgtta gtgaatggca tgaagtactc agacatagat attatcctac ttaagggtga
     1081 tgttgaagaa gacgaaacga ttcctgatag tgaacaggat atacggccac gttttcaccg
     1141 atcgaggacg gtggctcagc agcatgatga agatggaatt gaagaggaag atgatgatga
     1201 tgatgaaatt gatgatgatg atacaatttc tgactggaat ctaagaaaat gttctgctgc
     1261 tgccctggat gttcttgcaa atgtgtatcg tgatgaactg ctgccacata ttttgcccct
     1321 tttgaaagaa ttactttttc atcatgaatg ggttgttaaa gaatcaggca ttttggtttt
     1381 aggagcaatt gctgaaggtt gcatgcaggg catgattcca tacttgcctg agcttattcc
     1441 tcaccttatt cagtgcctct ctgataaaaa ggctcttgtg cgttccataa catgctggac
     1501 tcttagccgc tatgcacact gggtggtcag ccagccgcca gacacgtacc tgaagccatt
     1561 aatgacagaa ttgctaaagc gcatcctgga cagcaacaag agagtacaag aagctgcctg
     1621 cagtgccttt gctaccctag aagaggaggc ttgtacagaa cttgttcctt accttgctta
     1681 tatacttgat accctggtct ttgcatttag taaataccag cataagaacc tgctcattct
     1741 ttacgatgcc ataggaacat tagcagattc agtaggacat catttaaaca aaccagaata
     1801 tattcagatg ctaatgcctc cactgatcca gaaatggaac atgttaaagg atgaagataa
     1861 agatctcttc cctttacttg agtgcctatc ttcagttgcc acagcactgc agtctggatt
     1921 ccttccgtac tgtgaacctg tgtatcagcg ttgtgtaaac ctagtacaga agactcttgc
     1981 acaagccatg ctaaacaatg ctcaaccaga tcaatatgaa gctccagata aagattttat
     2041 gatagtggct cttgatttac tgagtggcct ggctgaagga cttggaggca acattgaaca
     2101 gctggtagcc cgaagtaaca tcctgacact aatgtatcag tgcatgcagg ataaaatgcc
     2161 agaagttcga cagagttctt ttgccctgtt aggtgacctc acaaaagctt gctttcagca
     2221 tgttaagcct tgtatagctg atttcatgcc aatattggga accaacctaa atccagaatt
     2281 catttcagtc tgcaacaatg ccacatgggc aattggagaa atctccattc aaatggcaat
     2341 aacaattggt cgtcttggtt acgtttgtcc tcaagaggtg gcccccatgc tacagcagtt
     2401 tataagaccc tggtgcacct ctctgagaaa cataagagac aatgaggaaa aggattcagc
     2461 attccgtgga atttgtacca tgatcagtgt gaatcccagt ggcgtaatcc aagattttat
     2521 atttttttgt gatgccgttg catcatggat taacccaaaa gatgatctca gagacatgtt
     2581 ctgtaagatc cttcatggat ttaaaaatca agttggcgat gaaaattgga ggcgtttctc
     2641 tgaccagttt cctcttccct taaaagagcg tcttgcagct ttttatggtg tttaatctaa
     2701 tacacttaag ctgcagtccc aaaattaggg gtccttcagt cttggagact ataagggagc
     2761 ctctgcaccc agggaaaatg ttacccttta caggggggaa gggtaaacca gtagggaata
     2821 cagtacaatc ccaaccctac tgggaggggc gggagggagg tgttgccgtc actgtattaa
     2881 gtcgatgttg ggaaacgttt taacatctgg agcctttgtg ggtggaaata tgtctccagt
     2941 tacaactccg cagtggatgt gaagaagcaa aaaaaaaaaa atctattcag tctactcaca
     3001 aaacagtaca ttgtggaata ttatggggaa ttgtaccaaa acaagaacca tataaatgat
     3061 gcctagggac aagaaagagg aacaattcta tagcgcacaa taaaggaaac ctaagaatgg
     3121 gagttacaaa tagtaaagaa gctttttttt tttttttaat ttaaagtttt tttatgtaag
     3181 ttttcccaca tgatggggcc ttgttttgca tgttgatgaa gaactacaca aagaaaacta
     3241 atatagttaa aagtcagctt gccttcccgt agtagaagca ggttcttgga agttacaatt
     3301 taaggtaccc caaaaaagtt ggaaataaaa caaaacaaac ataaacaatg aagcaccctg
     3361 tgaaatgcca aatgagtcac tccttttacc ttttttgggg tgggcaggga gggaggaata
     3421 aatggggttg ggcatatcaa actaaagatg acatcttaat tttgcattga acattaatgt
     3481 agcggatata atttgatgat tatacttcat tagatttaat ttctaggcca agatgttact
     3541 ttttaaagtg cagtttaagg ttcaggcatg cattctggct catagtggtt gaaagtaatt
     3601 taaattagtg ggaaagtagc atgcttgcat cacatagagt gagattggta ttcatttacc
     3661 tatgttgcgc cagtttgtgt tgcagtttac caattcaata tagccctgca tttaaagttc
     3721 ctttttaaga tttgtggatt ttatttttat taagaacata gatatataaa gtactgtagt
     3781 ttacaggtag gccttgaaat atctttttta ggatctgtta ggaataagat tgatattgta
     3841 ttgtgtgtaa cctgcacaat gtggaaagct gatatacctg tgcaaaatct ttgcctctgt
     3901 gctgtcagtg tgatgtgctt tctgcatggt tatatactac tagtgatttt atcaaaactt
     3961 ctaaaattta aattacgtgg taaaagatct gtaaaaggct gcataaatgt tagttggcac
     4021 ataaagacaa ttgtagaagt tgaaaaatga ttgctatatt tcaatgttta ttcccactca
     4081 acatactgcc ttctaagctt cccttttttt gttcaaagca tgatcttaaa gatatgttta
     4141 agttaatgga tgtaatgcag ggttcctaca ctgtattttg gcgcatgttg gtggccctct
     4201 gtgccctaga tatatgcaca cagggtgcaa gttaaaagct acagagtgaa agttggtttg
     4261 gatcctcttc atttcatttg tttagctttt ctgttatttt tctctactta catgtattcc
     4321 tgtgaataaa tccttgttaa gttaaccctt tacttttcct tccatgtgta ttttcttata
     4381 tactgtgaat gtgaaaacct aactggtaca cttgatcttg tgttcatatg aaagtgcaag
     4441 tctttattaa tttggattgc ctgaacagtg tatcccatga tgatgaagga aaatggagag
     4501 atttttcttt ttaactctgc tggtcagaga tgaagccacg cctttccatt tttcaatgct
     4561 gcatatttaa tctgcaacaa aaatgttaag ccataacagc ctttttatat tttagtttgt
     4621 cacctttgca ttgcagaata aatactgaat aaccattttt ataagcagtt gctcctcttt
     4681 gcatggttct attctctaaa agtgttgaat gatacagcca ttgcactgaa gtttgagctg
     4741 tgtgcgtgtg aatttatact gtttcaaaaa tttcaaatgc atggtagcat gtagaaaggt
     4801 ttttgttact atgtgtgtgt gtgtgttttg ttttgttttg ttctgttttt taacgttctt
     4861 tcacctttcc tctactttgg ctttgcaaat ttcagtctgt agagcctgaa attaaattat
     4921 tttatagtgc ctgatatttt taatattata agttggattc aaagggtata cagcattttg
     4981 ttttctagta ccattgcttc actgggagct caaaatttgc ctccctgtta gtctttaata
     5041 actgagtaga gtagcttttt tattcttaga ttatagtgat attctgtagt gcttcaaata
     5101 cttagaattc taatatgaga gatagtttaa tattctggaa tagagagtat tttaaattga
     5161 aatgaccaaa ttcgatttaa aacaaacaca taacaatctt cagtaaagtt atttgaacct
     5221 gtggttgaca attctgtatt gactaaaggc aatattgtca cctgtctcat taaaaattag
     5281 tttccagtta ggcagatgaa taacactatt aaaaatgcac ccagttttgt agtcacttga
     5341 cttttttttt ttatttaaat gaaatttaat ttgaaaatag aaaataaaat taggtaaata
     5401 tgactggcaa cctgaatttg agttgggatt ctttgtgtat ttttccccct tgaggttatt
     5461 gtttcttcct aatttatatt tcagatacat agtgtagaac aggaatttgc agaagccatt
     5521 taagttatct tttgaggtaa gctctgattt agcatttatt ctgataaaat ctaatacatc
     5581 atgggatata tataaagcaa cttaattctt gtggtgtagt cttaatagtt ttgaatgttg
     5641 actgaatgtc tataaaattg tgagtttgtc tttgttacat tccagtgttt ctgcctcttg
     5701 gcatgcttaa agcacggctt acttcatctg ctccttacac actaaaatgc tgttagtgtg
     5761 ctcaactaca gaaatagccg ctgctaagtg atgtagattt tctacttgaa tatttttatg
     5821 ttgtaggaac ctcaggaggt cagtgtttac tgttttatat atgccttctt tttcctgttt
     5881 gagcttctct ctttgaagga ttctaacaga acaaagctgc tgatcaacct aagttggaaa
     5941 cagaaagtgt aattaatata acttaaatgc atgtttggca gttccatgtt acagtccatt
     6001 agcgagtgaa cttagtgcca caggtattca tttattcagg aaagaatttt gctttttgta
     6061 ttgtctaatc tcttcaatga cttcatactg tgtaaaaaaa aatcactttt taatattttt
     6121 tggttggtta tttcccaaat aatcaacatg taaataatct tttaagagcc agttctgatg
     6181 ctttacatta ttgctacttg attttgttat gcaagttaga tttcagaaga atagatttta
     6241 aaacacttaa ccaagccatt acatcttaaa aacaaaacaa gtagcataca ttttgtaatt
     6301 aacattgata aacactgtga tttttttggt taagactttt tcattgatct gaattgctta
     6361 aattgcatat attgtaaaat aggatcagat gtatatttta aactaatttc aatggatttt
     6421 cctcttgaaa tgctttgtct actcagttat aaaatattca gatacaagtt ttatctcagg
     6481 tgaatactct tgtattgttt ttgctttggt gacatgctta taaagggtca tcctagttac
     6541 attctttgtt ttttaagtgt atttcattga gaatctttcc atttagtctg atttttttcc
     6601 taatattcta gcaggctggg gtggtataaa gccctcctga caagcctttt gcctacaggt
     6661 ttacctgaaa atgagctaca tatggtcgtc attttcttca aactctcaaa ataggaaagt
     6721 ggaaattttt ctcccctata taaaattatt ctgcctagca gaaatgccag aaataaatta
     6781 attgcatctt agtctaaatt taagtccttt gccatgagga aaaagtggtt ttttgcttca
     6841 tatggtaaat ctatattatt catattgaat gtattaacag ataatggtgc aaaagcattc
     6901 ttcccagggg aagagtgtat catgcataac tgcaatttaa gtccttcctt tgataatact
     6961 tcaaaacata cacagctttg cttactgaat tatttttgca aataatacaa ggaggggaaa
     7021 ctaacttgct actagtgttg ttaatgaagt ataggccttg gaacatttaa gaaaactggt
     7081 cttcagatag ttaagggctt gggataattt aagtgaaaag tgagatcagt aatgagctgt
     7141 gttgttaaca atattatctg gtaataatac catgcaatat agcgttgtat accaacttag
     7201 tgcattttat actgtattaa atatggagat acttctaatg cctctctaaa attaaatttt
     7261 acataaaagt tagttttatt cacctttagg ctttccaagt gaattgtgac taattttttc
     7321 aatcttacat agatctttca cccattagca ttacttacgt agataattct ttatgcctag
     7381 ttattataca tattaatttt taaggtatac atttaaatta cacaattgtt cattgtggtt
     7441 tgtatcccag aatgtgttgt gttttttaaa agatgcataa tagctgaatg tatgcatgac
     7501 tttgaaagaa gttaaaatgg tgattttttt tcacctcttg tacattttaa aaccaggcca
     7561 aatctatttg ccaagcagtg tatcactaat aagaaaagca gtttttcctt ttattgcagt
     7621 ttttgtttat ctgccataga atttccttat actgtggctt ggtattattc aagattagct
     7681 atttcgctgg tattacatct ttttaaaagc ctattataac atggttagcc tataaggcag
     7741 tgttggtccc cttctaatat tggcctcata aaggggttcc actgtacttt ccgcatatta
     7801 ctgtgttgtt gttttccttt gtggatatat aagcaaattg agcttgggtg atttttatgg
     7861 agacaataat tagacaatac tgtataatta gttttactta atagattatc atcttgtgag
     7921 aagagatgtt taaacgtggt aaatcacttc atattacaaa acagttttac acttaatatg
     7981 ttaacattgg gtgcaataat ttagtagcat tagctttagt tacaaatata actggatctt
     8041 tctgctgaca acttaggttg tatgagttat gcttaaaagc tttaaatctg atgtttcctg
     8101 tacctgccac actatgttag aatgtgtcct tcaaacatat cctcctgcaa cttctcaaac
     8161 tgtactaaat tgatatttct tgaagtctaa ctctgtgcta acagatctcc attttaaata
     8221 gaatacggtt ttaatttttg ataagctgct gaattttaaa gagagttttt tggggccacc
     8281 aaatattttg gatcatgcag agaatatata ttgtactgta gtaattttgt atttacattt
     8341 gtatgatgtg acataataga tgtgaatgtt aatcactgct tgactatgtt aataaagttg
     8401 tttaactata
//
