LOCUS       NM_001395930             652 bp    mRNA    linear   PRI 08-APR-2024
DEFINITION  Homo sapiens thymosin beta 15C (TMSB15C), mRNA.
ACCESSION   NM_001395930
VERSION     NM_001395930.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 652)
  AUTHORS   Banyard,J., Barrows,C. and Zetter,B.R.
  TITLE     Differential regulation of human thymosin beta 15 isoforms by
            transforming growth factor beta 1
  JOURNAL   Genes Chromosomes Cancer 48 (6), 502-509 (2009)
   PUBMED   19296525
REFERENCE   2  (bases 1 to 652)
  AUTHORS   Ross,M.T., Grafham,D.V., Coffey,A.J., Scherer,S., McLay,K.,
            Muzny,D., Platzer,M., Howell,G.R., Burrows,C., Bird,C.P.,
            Frankish,A., Lovell,F.L., Howe,K.L., Ashurst,J.L., Fulton,R.S.,
            Sudbrak,R., Wen,G., Jones,M.C., Hurles,M.E., Andrews,T.D.,
            Scott,C.E., Searle,S., Ramser,J., Whittaker,A., Deadman,R.,
            Carter,N.P., Hunt,S.E., Chen,R., Cree,A., Gunaratne,P., Havlak,P.,
            Hodgson,A., Metzker,M.L., Richards,S., Scott,G., Steffen,D.,
            Sodergren,E., Wheeler,D.A., Worley,K.C., Ainscough,R.,
            Ambrose,K.D., Ansari-Lari,M.A., Aradhya,S., Ashwell,R.I.,
            Babbage,A.K., Bagguley,C.L., Ballabio,A., Banerjee,R., Barker,G.E.,
            Barlow,K.F., Barrett,I.P., Bates,K.N., Beare,D.M., Beasley,H.,
            Beasley,O., Beck,A., Bethel,G., Blechschmidt,K., Brady,N.,
            Bray-Allen,S., Bridgeman,A.M., Brown,A.J., Brown,M.J., Bonnin,D.,
            Bruford,E.A., Buhay,C., Burch,P., Burford,D., Burgess,J.,
            Burrill,W., Burton,J., Bye,J.M., Carder,C., Carrel,L., Chako,J.,
            Chapman,J.C., Chavez,D., Chen,E., Chen,G., Chen,Y., Chen,Z.,
            Chinault,C., Ciccodicola,A., Clark,S.Y., Clarke,G., Clee,C.M.,
            Clegg,S., Clerc-Blankenburg,K., Clifford,K., Cobley,V., Cole,C.G.,
            Conquer,J.S., Corby,N., Connor,R.E., David,R., Davies,J., Davis,C.,
            Davis,J., Delgado,O., Deshazo,D., Dhami,P., Ding,Y., Dinh,H.,
            Dodsworth,S., Draper,H., Dugan-Rocha,S., Dunham,A., Dunn,M.,
            Durbin,K.J., Dutta,I., Eades,T., Ellwood,M., Emery-Cohen,A.,
            Errington,H., Evans,K.L., Faulkner,L., Francis,F., Frankland,J.,
            Fraser,A.E., Galgoczy,P., Gilbert,J., Gill,R., Glockner,G.,
            Gregory,S.G., Gribble,S., Griffiths,C., Grocock,R., Gu,Y.,
            Gwilliam,R., Hamilton,C., Hart,E.A., Hawes,A., Heath,P.D.,
            Heitmann,K., Hennig,S., Hernandez,J., Hinzmann,B., Ho,S., Hoffs,M.,
            Howden,P.J., Huckle,E.J., Hume,J., Hunt,P.J., Hunt,A.R.,
            Isherwood,J., Jacob,L., Johnson,D., Jones,S., de Jong,P.J.,
            Joseph,S.S., Keenan,S., Kelly,S., Kershaw,J.K., Khan,Z.,
            Kioschis,P., Klages,S., Knights,A.J., Kosiura,A., Kovar-Smith,C.,
            Laird,G.K., Langford,C., Lawlor,S., Leversha,M., Lewis,L., Liu,W.,
            Lloyd,C., Lloyd,D.M., Loulseged,H., Loveland,J.E., Lovell,J.D.,
            Lozado,R., Lu,J., Lyne,R., Ma,J., Maheshwari,M., Matthews,L.H.,
            McDowall,J., McLaren,S., McMurray,A., Meidl,P., Meitinger,T.,
            Milne,S., Miner,G., Mistry,S.L., Morgan,M., Morris,S., Muller,I.,
            Mullikin,J.C., Nguyen,N., Nordsiek,G., Nyakatura,G., O'Dell,C.N.,
            Okwuonu,G., Palmer,S., Pandian,R., Parker,D., Parrish,J.,
            Pasternak,S., Patel,D., Pearce,A.V., Pearson,D.M., Pelan,S.E.,
            Perez,L., Porter,K.M., Ramsey,Y., Reichwald,K., Rhodes,S.,
            Ridler,K.A., Schlessinger,D., Schueler,M.G., Sehra,H.K.,
            Shaw-Smith,C., Shen,H., Sheridan,E.M., Shownkeen,R., Skuce,C.D.,
            Smith,M.L., Sotheran,E.C., Steingruber,H.E., Steward,C.A.,
            Storey,R., Swann,R.M., Swarbreck,D., Tabor,P.E., Taudien,S.,
            Taylor,T., Teague,B., Thomas,K., Thorpe,A., Timms,K., Tracey,A.,
            Trevanion,S., Tromans,A.C., d'Urso,M., Verduzco,D., Villasana,D.,
            Waldron,L., Wall,M., Wang,Q., Warren,J., Warry,G.L., Wei,X.,
            West,A., Whitehead,S.L., Whiteley,M.N., Wilkinson,J.E.,
            Willey,D.L., Williams,G., Williams,L., Williamson,A.,
            Williamson,H., Wilming,L., Woodmansey,R.L., Wray,P.W., Yen,J.,
            Zhang,J., Zhou,J., Zoghbi,H., Zorilla,S., Buck,D., Reinhardt,R.,
            Poustka,A., Rosenthal,A., Lehrach,H., Meindl,A., Minx,P.J.,
            Hillier,L.W., Willard,H.F., Wilson,R.K., Waterston,R.H., Rice,C.M.,
            Vaudin,M., Coulson,A., Nelson,D.L., Weinstock,G., Sulston,J.E.,
            Durbin,R., Hubbard,T., Gibbs,R.A., Beck,S., Rogers,J. and
            Bentley,D.R.
  TITLE     The DNA sequence of the human X chromosome
  JOURNAL   Nature 434 (7031), 325-337 (2005)
   PUBMED   15772651
REFERENCE   3  (bases 1 to 652)
  AUTHORS   Gevaert,K., Goethals,M., Martens,L., Van Damme,J., Staes,A.,
            Thomas,G.R. and Vandekerckhove,J.
  TITLE     Exploring proteomes and analyzing protein processing by mass
            spectrometric identification of sorted N-terminal peptides
  JOURNAL   Nat Biotechnol 21 (5), 566-569 (2003)
   PUBMED   12665801
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC234783.5.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CK300729.1, CK818489.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2155371, SAMN03267758
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000598087.4/ ENSP00000472749.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-97                AC234783.5         59255-59351
            98-214              AC234783.5         61134-61250
            215-652             AC234783.5         62167-62604
FEATURES             Location/Qualifiers
     source          1..652
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xq22.2"
     gene            1..652
                     /gene="TMSB15C"
                     /gene_synonym="TMSB15B"
                     /note="thymosin beta 15C"
                     /db_xref="GeneID:122394733"
                     /db_xref="HGNC:HGNC:55173"
     exon            1..97
                     /gene="TMSB15C"
                     /gene_synonym="TMSB15B"
                     /inference="alignment:Splign:2.1.0"
     exon            98..214
                     /gene="TMSB15C"
                     /gene_synonym="TMSB15B"
                     /inference="alignment:Splign:2.1.0"
     CDS             115..252
                     /gene="TMSB15C"
                     /gene_synonym="TMSB15B"
                     /note="thymosin beta-15B; thymosin beta 15B-like"
                     /codon_start=1
                     /product="thymosin beta-15C"
                     /protein_id="NP_001382859.1"
                     /db_xref="CCDS:CCDS94644.1"
                     /db_xref="GeneID:122394733"
                     /db_xref="HGNC:HGNC:55173"
                     /translation="MSDKPDLSEVEKFDRSKLKKTNTEEKNTLPSKETIQQEKECVQT
                     S"
     exon            215..652
                     /gene="TMSB15C"
                     /gene_synonym="TMSB15B"
                     /inference="alignment:Splign:2.1.0"
     regulatory      634..639
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TMSB15C"
                     /gene_synonym="TMSB15B"
                     /note="hexamer: AATAAA"
     polyA_site      652
                     /gene="TMSB15C"
                     /gene_synonym="TMSB15B"
                     /note="major polyA site"
ORIGIN      
        1 agcactgcag ggctctgggc gggaaggcta acctggtgcg gagccagcct gggtctcagc
       61 cccgcgtacg gcctttcacg agtcttcaag ccttcaggct ttcttctagt caagatgagt
      121 gataaaccag acttgtcgga agtggagaag tttgacaggt caaaactgaa gaaaactaat
      181 actgaagaaa aaaatactct tccctcaaag gaaactatcc agcaggagaa agagtgtgtt
      241 caaacatcat aaaatgggga tctcctccaa agagcagatt tcagcattgc ctgacagtct
      301 tggttttagg cttgtttttt tgtaaacctg tgtgtttgta gagatttcag acatcttctg
      361 atttcttctc acctatattc cctggttaag aggtcagggg tagtgaatgt ttccttaagt
      421 tcctttttaa acttcccatt ggtatgtaaa ttccaaatgg cagatgctgt caataacctt
      481 gccatggatg acctttgtgt aggtagtcct tgcacctcat gcaggataag ccaattttaa
      541 ctttctacaa tgggtgcctc aatagtttca taatcttcat gaagttgcat cctttggcag
      601 cttcttacag tttattttca cttccaatgt agcaataaaa taataaatat aa
//
