LOCUS       NM_014548               9150 bp    mRNA    linear   PRI 09-FEB-2024
DEFINITION  Homo sapiens tropomodulin 2 (TMOD2), transcript variant 1, mRNA.
ACCESSION   NM_014548
VERSION     NM_014548.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 9150)
  AUTHORS   Zhao,M.L., Wang,J.X., Bian,X.K., Zhang,J., Han,Y.W., Xu,S.X.,
            Lee,S.C. and Zhao,J.Z.
  TITLE     Hexavalent chromium causes centrosome amplification by inhibiting
            the binding between TMOD2 and NPM2
  JOURNAL   Toxicol Lett 380, 12-22 (2023)
   PUBMED   36963620
  REMARK    GeneRIF: Hexavalent chromium causes centrosome amplification by
            inhibiting the binding between TMOD2 and NPM2.
REFERENCE   2  (bases 1 to 9150)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   3  (bases 1 to 9150)
  AUTHORS   Pawlak,G., McGarvey,T.W., Nguyen,T.B., Tomaszewski,J.E.,
            Puthiyaveettil,R., Malkowicz,S.B. and Helfman,D.M.
  TITLE     Alterations in tropomyosin isoform expression in human transitional
            cell carcinoma of the urinary bladder
  JOURNAL   Int J Cancer 110 (3), 368-373 (2004)
   PUBMED   15095301
  REMARK    GeneRIF: levels of TM1, TM2 and TM3 are reduced in human
            transitional cell carcinoma cells, but significantly upregulated by
            inhibition of the mitogen-activated protein kinase-signaling
            pathway
REFERENCE   4  (bases 1 to 9150)
  AUTHORS   Cox,P.R. and Zoghbi,H.Y.
  TITLE     Sequencing, expression analysis, and mapping of three unique human
            tropomodulin genes and their mouse orthologs
  JOURNAL   Genomics 63 (1), 97-107 (2000)
   PUBMED   10662549
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from DA808222.1, BC064961.1 and
            AC090971.3.
            
            On Nov 22, 2018 this sequence version replaced NM_014548.3.
            
            Summary: This gene encodes a neuronal-specific member of the
            tropomodulin family of actin-regulatory proteins. The encoded
            protein caps the pointed end of actin filaments preventing both
            elongation and depolymerization. The capping activity of this
            protein is dependent on its association with tropomyosin.
            Alternatively spliced transcript variants encoding different
            isoforms have been described. [provided by RefSeq, Dec 2008].
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660803.54106.1,
                                           SRR1660805.107963.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000249700.9/ ENSP00000249700.4
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-85                DA808222.1         37-121
            86-1974             BC064961.1         70-1958
            1975-9150           AC090971.3         14956-22131
FEATURES             Location/Qualifiers
     source          1..9150
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="15"
                     /map="15q21.2"
     gene            1..9150
                     /gene="TMOD2"
                     /gene_synonym="N-TMOD; NTMOD"
                     /note="tropomodulin 2"
                     /db_xref="GeneID:29767"
                     /db_xref="HGNC:HGNC:11872"
                     /db_xref="MIM:602928"
     exon            1..116
                     /gene="TMOD2"
                     /gene_synonym="N-TMOD; NTMOD"
                     /inference="alignment:Splign:2.1.0"
     exon            117..311
                     /gene="TMOD2"
                     /gene_synonym="N-TMOD; NTMOD"
                     /inference="alignment:Splign:2.1.0"
     CDS             186..1241
                     /gene="TMOD2"
                     /gene_synonym="N-TMOD; NTMOD"
                     /note="isoform a is encoded by transcript variant 1;
                     neuronal tropomodulin; tropomodulin 2 (neuronal)"
                     /codon_start=1
                     /product="tropomodulin-2 isoform a"
                     /protein_id="NP_055363.1"
                     /db_xref="CCDS:CCDS10144.1"
                     /db_xref="GeneID:29767"
                     /db_xref="HGNC:HGNC:11872"
                     /db_xref="MIM:602928"
                     /translation="MALPFQKELEKYKNIDEDELLGKLSEEELKQLENVLDDLDPESA
                     MLPAGFRQKDQTQKAATGPFDREHLLMYLEKEALEQKDREDFVPFTGEKKGRVFIPKE
                     KPIETRKEEKVTLDPELEEALASASDTELYDLAAVLGVHNLLNNPKFDEETANNKGGK
                     GPVRNVVKGEKVKPVFEEPPNPTNVEISLQQMKANDPSLQEVNLNNIKNIPIPTLREF
                     AKALETNTHVKKFSLAATRSNDPVAIAFADMLKVNKTLTSLNIESNFITGTGILALVE
                     ALKENDTLTEIKIDNQRQQLGTAVEMEIAQMLEENSRILKFGYQFTKQGPRTRVAAAI
                     TKNNDLVRKKRVEADRR"
     exon            312..468
                     /gene="TMOD2"
                     /gene_synonym="N-TMOD; NTMOD"
                     /inference="alignment:Splign:2.1.0"
     exon            469..591
                     /gene="TMOD2"
                     /gene_synonym="N-TMOD; NTMOD"
                     /inference="alignment:Splign:2.1.0"
     exon            592..678
                     /gene="TMOD2"
                     /gene_synonym="N-TMOD; NTMOD"
                     /inference="alignment:Splign:2.1.0"
     exon            679..809
                     /gene="TMOD2"
                     /gene_synonym="N-TMOD; NTMOD"
                     /inference="alignment:Splign:2.1.0"
     exon            810..917
                     /gene="TMOD2"
                     /gene_synonym="N-TMOD; NTMOD"
                     /inference="alignment:Splign:2.1.0"
     exon            918..1061
                     /gene="TMOD2"
                     /gene_synonym="N-TMOD; NTMOD"
                     /inference="alignment:Splign:2.1.0"
     exon            1062..1206
                     /gene="TMOD2"
                     /gene_synonym="N-TMOD; NTMOD"
                     /inference="alignment:Splign:2.1.0"
     exon            1207..9150
                     /gene="TMOD2"
                     /gene_synonym="N-TMOD; NTMOD"
                     /inference="alignment:Splign:2.1.0"
     regulatory      9126..9131
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TMOD2"
                     /gene_synonym="N-TMOD; NTMOD"
                     /note="hexamer: AATAAA"
     polyA_site      9150
                     /gene="TMOD2"
                     /gene_synonym="N-TMOD; NTMOD"
                     /note="major polyA site"
ORIGIN      
        1 gttgatcgcc gcgctcgccc cggccacggc gccgcccctg ttctcccggc cccgctccac
       61 cggggctgac ggactgacgg ccagcacagc cggctccggg atgagcgcac ggacggtatt
      121 ctgaagtctc aggaaactgg accatttaaa tgtgcatggc ccatgagaaa ggcttataag
      181 aagccatggc actccccttt caaaaagagc tggagaaata caagaacatt gatgaagatg
      241 agcttcttgg caaactctca gaagaggaac tgaaacagtt ggaaaatgtt ctagatgacc
      301 tagatcctga gagtgccatg ctgccagctg gatttcgaca gaaagaccag acacagaagg
      361 cagccaccgg cccctttgac cgcgagcacc tcctcatgta cctggagaag gaggctttgg
      421 aacagaaaga cagagaggac tttgtgccct tcactggaga aaagaaaggg agagtcttta
      481 tccctaaaga aaagcctata gaaactcgta aagaagaaaa agtgaccctt gacccagaac
      541 tggaagaagc tttggccagt gcctctgaca ccgaactcta tgatcttgca gctgtccttg
      601 gagtacacaa tttgctcaac aatccaaagt tcgatgaaga aacagccaac aataaaggtg
      661 gcaaaggacc tgtcagaaat gttgtcaaag gtgaaaaagt aaagccagta tttgaggaac
      721 caccaaatcc cacaaatgtg gaaataagcc tgcagcagat gaaagccaat gatcctagct
      781 tgcaagaagt caacctcaac aacattaaga acattccaat tccaaccctg agggaatttg
      841 caaaggctct ggagaccaac actcacgtga agaagttcag cctggccgca actcgcagca
      901 atgaccctgt ggccattgct tttgcagaca tgctgaaagt aaacaagacc ttgacaagtc
      961 taaacataga atccaatttt atcactggaa ctgggatcct ggccctggta gaggcactga
     1021 aagaaaatga caccttgaca gaaatcaaga ttgacaacca gaggcagcag ttgggaacag
     1081 ctgtagagat ggaaattgcc cagatgctgg aggagaattc aaggatcctc aagtttggat
     1141 accagtttac caagcaaggg ccacgaacaa gggtggcagc tgccatcaca aagaataatg
     1201 acctggttcg taagaagaga gttgaagcag accgaaggta aacttccttg aggagaagtg
     1261 aagtttcact gtggtatggc cattgaaaaa caaaaactct tcttcttccc catcaggacc
     1321 attttatcaa agttcgttca tttccgttaa ccacataact aataatttaa ttgttattct
     1381 tttttagcac tacttattta tcttggattt tgtaatatat gcaattgttt tatttgctca
     1441 tgggcacttc tggcaacttg acaaatggac cgatgcagat tttagagagt gacgacatgg
     1501 aaaatgaatt taaccacttt cttattgggt tgtcttgctt tcttacatga acttgttttt
     1561 ttaatcactg aaaggaattt agtgtataat atgtgtttgt aactgtgatt atgatagagg
     1621 cctatctctg tttacatgca tagctttgag ttaggctaaa tacatcagaa gtgttctact
     1681 gaccacataa gaagttagta ttgccaatct ttcactgcat gtgaaaatgt gaccaattta
     1741 gcacaaattc tctcttagtt ccagaaaaat cagtaaatgc acatgccctg ttgattggag
     1801 atcagtagtg tcatcttcat aaagcaagac aacattatga cactttaaaa cagtagcaaa
     1861 gaagtctatt tattaaccca caaatgtagc atcaagccag actcacaggt agcaaaatga
     1921 attacacacc tacttttact gactattcaa cataaattga atctttaaca tgactttaaa
     1981 ggctatttac aaagctgttt taaagttttt caaacatgat agaaattttc taaattttag
     2041 taagagagaa gcttttaaaa cagtacattc ctgaataaaa caacaatatt gtatcttaat
     2101 caaggctgtc tgatgcagat gattgcattt tttggcaaat tttagaagca tttattgctt
     2161 tgtctttagt gtaacaagat cactggatta aatataaaca ttcaggttaa ttatctagat
     2221 ttttgtccac agtatatgat ccatccagac atttgcaaac gtcaggagaa aaatgtgaat
     2281 tatttatcca gatgcatgtc atctcaagga caaagcctgt gaaagtacaa gtgagatggt
     2341 tgcattgtag tatgcattaa tctttcaatg tagtggtgta aaaatgcagt gctaaactaa
     2401 tgaagcaggt gactgcagcc tttggctcaa gctcacaact ctgataactg tcagtgcctg
     2461 aggttgtgat tggtgacatt ctgacactgc ccaaggcaac tcaccctcta ttcctccttt
     2521 ctcccctccc tttcttccaa ttcattgtct tttttttcct cttttctctg taatttgtta
     2581 ctaaacaaat tccagaattt gtttagtagc tgagtgttcc tgagttgcct agtagcaata
     2641 aaacaagtga ataggaaaat aattaatata ttattctatt tagcttgtaa aacacatgga
     2701 atctgtttaa gatagccctt gtaaaattga acatttacct gtattgtaag tacccacatc
     2761 tgtgtctctg aagtcctttg aaacatctca ttatcttgaa atttttttaa tgtttgagaa
     2821 caccataagc agaatattct aacacctttg gcccctgaaa atcctttaat tagtttatgg
     2881 cttcatctcc ttatctattt aaaaaacata gtaaataatg tttatggttt tcagtctgat
     2941 ttttccttcc ctttcaccca tttaggtgtg atgtgttgga gtcaacttgt acaggcttgc
     3001 caactgttat attttcaaga attttgcaaa ctggttgttc aatacagcca ttatttaaaa
     3061 ttaaatgatg tgcacttaca actgaatgaa ttatattaag gacagaagta acaaatactg
     3121 tactcaaaaa tcttacattt tactattttc taacctctta gattatttac atctagtagg
     3181 tatgtatgta gaaatattac caaacagtat gctactgaac gtatcctctc aactccatgt
     3241 tcactacctt cttgttacta cagtggcttg aaattggcca tggtagaaat atttacacca
     3301 cagaaattag caatatgtaa gaaattgggg ttttctccct ctccagattg ctggttgata
     3361 aacattcatc agcacaccac tgggtgaaat tatacatttt tttatacata tgtttcgctt
     3421 atcatgttgc cgaagggaag aacatttctc ttagatgtct tttctcctct ttggatttgt
     3481 tacaaacctg tttaagtgct gagtccctga cctgcctctc caagtaagcc tttttccttt
     3541 tttttttttt ttttcttact ctcattcttg ccttgactct taaaatcctg gaccctatag
     3601 agcattcctt gcagccccac agtgctgtgg gctgggggct aaagcagttc ttggcaaact
     3661 ctggcagaaa gcaagaaaaa aagaatcaga attcaatcat ggctgtttct tttgtacaag
     3721 cagttgttga tagtattaaa gcaagataat gggacattat caaaaatata gcactgtttt
     3781 taccttatga aatagttggg ttgcatgcaa cagagtctat gaaatcaaat gttttttact
     3841 aatcagtttg ttttcttatt acctgtgttt ttaaagtggc ttgaaaggtg gcatttccat
     3901 gagtgtgcac atattgatga taacccttag aaaaacatac acttgaggag cctatccatc
     3961 atttaattag cctaggactt catctccctc tctgcccaaa gtgtggaagt ggtagctctt
     4021 tcatgatcat gggcacagtt aatcctttgc tatccattgt gatggggcat aatgtatata
     4081 aaatattttt ctatgtattt gttctgccag atactgtgtt gagatatttg gcaatatctg
     4141 gataactgac tgaagggaga taacttctcc ccaggcctat ctccctcccc cttttagagt
     4201 tgtgcaggtc cactttaagt gtaaaatcac tcacctggac ttgtgggctt gtatcaccaa
     4261 catctattat ggcacatgta gatgacattt aggagaaaaa ccttagaagt ctagaaatca
     4321 tatgattagt tcagcactgc agctccccat ctgcttatag tgtataactg gaagctcttt
     4381 catcctcatc agcatgatta aatgacttcg tttctttcat ctttggaggg tataatgtaa
     4441 ataagtgtcg tgtgtgtatg tgtgtgtgta ctgtcagata tctaactagg tatttggcta
     4501 catctggaca actgattgaa gggagatgct ctctccccag tcctcttccc ttgtcctttt
     4561 tagaattgct gcaggcccag gttaaatatg aaattactcc ctaggctttg cagtttatgt
     4621 taccaaccac cacattttat agctatgtag aggatgactc ttaggaaata aatattagaa
     4681 gcctagaaat catttagttg ttctagcacc aaatctatcc atttgcctaa tgtatttaac
     4741 attccatcct catcaacatg atgaagcccc tttcttccat ctttgtaggg cacattgtat
     4801 ataaatattt tgtacataaa gatcatcaaa taccataatg gggtatttgg cttcatctgg
     4861 aaaattgact ggagggagat gctgtctccc agccctgctt ccctcgtccc tgtccaagtt
     4921 gctgcaggcc caggttagaa gattaccaac ctggaggggc atgcagttca tcttacaata
     4981 aaagcccatt catttaaaaa ctcagaaatc atcccagtgc ctgtactcct caaaccaatt
     5041 tccctaaggg aagactggca caccagccca aagagcaggt gcttctcttc caacagaaac
     5101 atggcccctg acagggcacc agcattaggg aaaccaatgt cctccgaata gctgccatga
     5161 gaacatttca gatgctcaaa ctgaaaattc ttaaaaccaa tattaagcat cagcatgctt
     5221 taagtgtaag atagcccttt ggaatttaca aacacatgtg cagctatttc cttcttcaca
     5281 gatatgatgt actcagcccc ctcctaggca ctacgaagaa gacagaggaa gcataaaaat
     5341 tctggactaa tataatttta tatgtgtttc tgagattggg gagtagactg agtgcctttt
     5401 ttacaaagaa gatcccatat ttaattcaag tatttatagc atcagcaaaa atgggcagag
     5461 ggcgggaagt tgagaacact aggttctgtg ctatgttacc tgtattcagt agaagtgttt
     5521 ctggagtcag gttttaagtc atgatcctga agcttccttc ccctcttcca ctaatgatgc
     5581 aataatagct gttttcattt taacgagcag agaactaaga ggaaaggtcc tagctctgcc
     5641 ttccacttgc agcttccctt tacctcctct tattgctttc atctcaaata tccctgctac
     5701 tcaaccaatc ctaaagctaa agtactgaga tgcacacaaa ggaaaggtgt gagagtgctt
     5761 ggaagcatcc agctgagccc actggatgaa aatcagacga tagggcctcc tgttgtaata
     5821 tactagccag agaaaagcgc caagaacttc agggatatta ttcactgctt tattgctccc
     5881 taaccctaga tcagattgga ttttactttg tagttcagga gttaagaagt caaattgctg
     5941 accgaggtgg ggaaggatga tggaaattaa aggtttacat ttgtttaatg gcagaactga
     6001 gatttgctca gcttatctct ttcccatctg tctgtaatag caatgactga ataatcagta
     6061 gaccaatgga agaggagttg caagtttaaa tttgtaacct gactctgggt tctgttctag
     6121 gaatagtgca tgttttagag gctttgccag ttgggataca ttgttgactt gggggaggat
     6181 gaaggagaga actgatgacc tagacataga aaagagtagt taactaacta gatgttcttc
     6241 tgatctcttc catggtagac attctgagca cattggccca gttagttggt atggtgaagg
     6301 ggcaccgtac taacagattt ggagactgaa acctaatccc atcaccaaca cttagcaggt
     6361 atatgatcat gggcaattca ttcaattgcc tgccaattat agactatata gggggaagag
     6421 cactggattt ggagtcaaga aacctggaca cttggctcca cacttcctta gctgggtaac
     6481 tttgggcaaa ccgcttggtc tctcaagcct aaggttcttc agctataaaa tgggaataat
     6541 acttcactaa ctacctcaca gagttgtggt aagaatataa tcagataact ggataaaaac
     6601 actatataaa ctggaaagcg ccgtacaaat gtgagagatc agttttatta tcaaatcact
     6661 gttttccact gcctcttgaa tcggctttat tctaaccaac cattacatct ttctcatctt
     6721 ttggagtatg ggtaattgag gcttgggtgt gtcatcaggg actggagtta tttcagctcc
     6781 catgtagagg tgggagaggt ggttgatggg gcagtggaag ttagatacca gcgatgtata
     6841 tggtaggaca ttttcctggg tcactttgac agtaccttgg gaaattgtca gtccttgcag
     6901 agggcctagg ctgggcacaa gggagaaagc gaacagttga ctaagaattg aggggagggt
     6961 ctggagcgct actgccctcc tgtcattgct gtgggtggga gaggctaaga cttcaggttt
     7021 gactggaggc ctaggagaga agagtgtcct tagggtttca agaattttaa tgcctagcag
     7081 ctgagtaaca ggcattagtt ctgatagata gtgaagggga gaaagtgcca cctgttgtga
     7141 gatcacctct ccagggcagc agctgccttg ttatcaccag caaccttagc cctggtcagt
     7201 aatatttctg ctaagaaagg ttttgaagca tggcctccaa tgactttcat aagcccttgg
     7261 aggcaggact gtgtctcatc catctttgta tcttcagtac catcttgtaa ggtgccttgt
     7321 acatagtagg tgcttaatga acaaatgttg cttgaattta gctgtcgtcc agccccacag
     7381 agttatgctc catttgccac catgtgatat ttttgagaaa caatagtgat ttggatgcca
     7441 gctctatgtg actttgggca agactctcca tctatcttgt cttcatttca tctgtaaaat
     7501 gaagtgagta gattcaatgc tccctaaggt cccttccagc tccaatactt gacaagcttg
     7561 tgattctaaa tcgtttccgt tgcctctgaa catgggtgag taatgcctcc actgcagctg
     7621 tttctctcca ggaggctttg ttcagaggag gtctgactat tgcacagcca gttttttctt
     7681 cctcttcagc agttctttac tgtcttcaga atggttctgg ataagcggcc ttttctgaaa
     7741 ggatatttaa aaatatatac tatttaggct gggcccagtg gctcatgcct gtaatcccag
     7801 cactttggga ggtgaaggtg ggtggatcac ctgaggtcag gagttcaaga ccagcctggc
     7861 caacatggtg aaaccccgtc tctactaaaa atacagaaat tagctgggcc ctgtggcaag
     7921 agcctgttat cccagctact ggggaggctg aggcaggaaa atcgcttgaa cccaggaggt
     7981 ggaggttgta gtgagccgag atcacaccac tgcactccag cctgggtgac aagaacgaaa
     8041 ctccatctca aaaaataaaa taaaatatat actatcttgc tcctcagaac cagtggggaa
     8101 gaagagggaa ggcaaagaaa gaaactgagc atagtaaaca cagcattttt ttgtaggctc
     8161 ttatttaaaa tgtgtgtgtg tgtgtgtatg tgtgtgtttc tgagtaagta ttgactggga
     8221 aaaagagaga agtcaatcaa aagtatactg tgcaattgag agaggctggc ccaagattta
     8281 aaacttcctg tgggtaatct aactgtgagt agataggaat cggccatatg acgaaatgag
     8341 atcaatagga aatgtgcttt ttgaggaaat tttattttag taccaaatgt tgccagtgac
     8401 aatcttcagt taagaagtaa gttattctga cctaaaattc ttatctctgc cactttggtt
     8461 taaaaacaaa aacccttata tacatggaat agttatattt taattaagca tttattttag
     8521 ttgttttcat ccattcaagc aaaatgaata agcagcattt ttcattgcac ttaaaaatgt
     8581 aaaatacctg catgccacta atctgtaaca ttttaccagt tcagatgcct gtaatgtgtg
     8641 actttatgtg tgtctgtgtt gttttgaaga gaataaagga aataatactt tgcaaactgt
     8701 ttaaacaagt gtttaaactt ctattggcaa catttattgg gctaagcagt tattgaaaac
     8761 tccgcatagt tttattttcc atttgaaact tcaatcaaat caagactatt atattcatta
     8821 gggaattaaa gactaatttg ctttttaaat gtgaagttga acactgtgtg gaaagtaaat
     8881 gtgtgatgaa gcaaaatgta taaagtatga aatattatac ttttaccctg gataattatt
     8941 caggacccca gttggcccaa ataggtgcaa tttttaatcc tttgaaatta gccagccaga
     9001 cctaatgcta aggtaaatgt aaactgtttt aattaattaa gatctttctg ctttcgaagg
     9061 tataatgtat ctatttctgt caggaatgat atttccaaat gaaaatgtaa agaacattgg
     9121 gaaataataa actttccttt caaagtaaaa
//
