LOCUS       NM_007114               6879 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens TATA element modulatory factor 1 (TMF1), transcript
            variant 1, mRNA.
ACCESSION   NM_007114
VERSION     NM_007114.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6879)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 6879)
  AUTHORS   Papadopoulos,N., Lennartsson,J. and Heldin,C.H.
  TITLE     PDGFRbeta translocates to the nucleus and regulates chromatin
            remodeling via TATA element-modifying factor 1
  JOURNAL   J Cell Biol 217 (5), 1701-1717 (2018)
   PUBMED   29545370
  REMARK    GeneRIF: In the nucleus, PDGFRbeta formed ligand-inducible
            complexes with the tyrosine kinase Fer and its substrate, TATA
            element-modifying factor 1 (TMF-1).
REFERENCE   3  (bases 1 to 6879)
  AUTHORS   de Boer,M., van Leeuwen,K., Geissler,J., Weemaes,C.M., van den
            Berg,T.K., Kuijpers,T.W., Warris,A. and Roos,D.
  TITLE     Primary immunodeficiency caused by an exonized retroposed gene copy
            inserted in the CYBB gene
  JOURNAL   Hum Mutat 35 (4), 486-496 (2014)
   PUBMED   24478191
  REMARK    GeneRIF: In patient with chronic granulomatous disease, a 5.8-kb,
            incomplete and partly exonized TMF1 transcript was identified in
            intron 1 of CYBB, in opposite orientation to the host gene.
REFERENCE   4  (bases 1 to 6879)
  AUTHORS   Miller,V.J., Sharma,P., Kudlyk,T.A., Frost,L., Rofe,A.P.,
            Watson,I.J., Duden,R., Lowe,M., Lupashin,V.V. and Ungar,D.
  TITLE     Molecular insights into vesicle tethering at the Golgi by the
            conserved oligomeric Golgi (COG) complex and the golgin TATA
            element modulatory factor (TMF)
  JOURNAL   J Biol Chem 288 (6), 4229-4240 (2013)
   PUBMED   23239882
  REMARK    GeneRIF: COG complex interacts with two different Rabs in addition
            to each end of the golgin 'TATA element modulatory factor' (TMF).
REFERENCE   5  (bases 1 to 6879)
  AUTHORS   Miyamoto-Sato,E., Fujimori,S., Ishizaka,M., Hirai,N., Masuoka,K.,
            Saito,R., Ozawa,Y., Hino,K., Washio,T., Tomita,M., Yamashita,T.,
            Oshikubo,T., Akasaka,H., Sugiyama,J., Matsumoto,Y. and Yanagawa,H.
  TITLE     A comprehensive resource of interacting protein regions for
            refining human transcription factor networks
  JOURNAL   PLoS One 5 (2), e9289 (2010)
   PUBMED   20195357
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 6879)
  AUTHORS   Zhang,Y., Fondell,J.D., Wang,Q., Xia,X., Cheng,A., Lu,M.L. and
            Hamburger,A.W.
  TITLE     Repression of androgen receptor mediated transcription by the
            ErbB-3 binding protein, Ebp1
  JOURNAL   Oncogene 21 (36), 5609-5618 (2002)
   PUBMED   12165860
REFERENCE   7  (bases 1 to 6879)
  AUTHORS   Mori,K. and Kato,H.
  TITLE     A putative nuclear receptor coactivator (TMF/ARA160) associates
            with hbrm/hSNF2 alpha and BRG-1/hSNF2 beta and localizes in the
            Golgi apparatus
  JOURNAL   FEBS Lett 520 (1-3), 127-132 (2002)
   PUBMED   12044884
REFERENCE   8  (bases 1 to 6879)
  AUTHORS   Hsiao,P.W. and Chang,C.
  TITLE     Isolation and characterization of ARA160 as the first androgen
            receptor N-terminal-associated coactivator in human prostate cells
  JOURNAL   J Biol Chem 274 (32), 22373-22379 (1999)
   PUBMED   10428808
REFERENCE   9  (bases 1 to 6879)
  AUTHORS   Schwartz,Y., Ben-Dor,I., Navon,A., Motro,B. and Nir,U.
  TITLE     Tyrosine phosphorylation of the TATA element modulatory factor by
            the FER nuclear tyrosine kinases
  JOURNAL   FEBS Lett 434 (3), 339-345 (1998)
   PUBMED   9742951
REFERENCE   10 (bases 1 to 6879)
  AUTHORS   Garcia,J.A., Ou,S.H., Wu,F., Lusis,A.J., Sparkes,R.S. and
            Gaynor,R.B.
  TITLE     Cloning and chromosomal mapping of a human immunodeficiency virus 1
            'TATA' element modulatory factor
  JOURNAL   Proc Natl Acad Sci U S A 89 (20), 9372-9376 (1992)
   PUBMED   1409643
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL040699.1, BC033771.2, AB209109.1, AC109587.2 and BU689613.1.
            
            On Nov 23, 2018 this sequence version replaced NM_007114.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660807.115054.1,
                                           SRR1660805.72959.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000398559.7/ ENSP00000381567.2
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-115               AL040699.1         1-115
            116-1825            BC033771.2         61-1770
            1826-4085           AB209109.1         1796-4055
            4086-6249           AC109587.2         116163-118326       c
            6250-6879           BU689613.1         17-646              c
FEATURES             Location/Qualifiers
     source          1..6879
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3p14.1"
     gene            1..6879
                     /gene="TMF1"
                     /gene_synonym="ARA160; TMF"
                     /note="TATA element modulatory factor 1"
                     /db_xref="GeneID:7110"
                     /db_xref="HGNC:HGNC:11870"
                     /db_xref="MIM:601126"
     exon            1..389
                     /gene="TMF1"
                     /gene_synonym="ARA160; TMF"
                     /inference="alignment:Splign:2.1.0"
     CDS             248..3529
                     /gene="TMF1"
                     /gene_synonym="ARA160; TMF"
                     /note="isoform 1 is encoded by transcript variant 1;
                     androgen receptor coactivator 160 kDa protein; androgen
                     receptor-associated protein of 160 kDa"
                     /codon_start=1
                     /product="TATA element modulatory factor isoform 1"
                     /protein_id="NP_009045.2"
                     /db_xref="CCDS:CCDS43105.1"
                     /db_xref="GeneID:7110"
                     /db_xref="HGNC:HGNC:11870"
                     /db_xref="MIM:601126"
                     /translation="MSWFNASQLSSFAKQALSQAQKSIDRVLDIQEEEPSIWAETIPY
                     GEPGISSPVSGGWDTSTWGLKSNTEPQSPPIASPKAITKPVRRTVVDESENFFSAFLS
                     PTDVQTIQKSPVVSKPPAKSQRPEEEVKSSLHESLHIGQSRTPETTESQVKDSSLCVS
                     GETLAAGTSSPKTEGKHEETVNKESDMKVPTVSLKVSESVIDVKTTMESISNTSTQSL
                     TAETKDIALEPKEQKHEDRQSNTPSPPVSTFSSGTSTTSDIEVLDHESVISESSASSR
                     QETTDSKSSLHLMQTSFQLLSASACPEYNRLDDFQKLTESCCSSDAFERIDSFSVQSL
                     DSRSVSEINSDDELSGKGYALVPIIVNSSTPKSKTVESAEGKSEEVNETLVIPTEEAE
                     MEESGRSATPVNCEQPDILVSSTPINEGQTVLDKVAEQCEPAESQPEALSEKEDVCKT
                     VEFLNEKLEKREAQLLSLSKEKALLEEAFDNLKDEMFRVKEESSSISSLKDEFTQRIA
                     EAEKKVQLACKERDAAKKEIKNIKEELATRLNSSETADLLKEKDEQIRGLMEEGEKLS
                     KQQLHNSNIIKKLRAKDKENENMVAKLNKKVKELEEELQHLKQVLDGKEEVEKQHREN
                     IKKLNSMVERQEKDLGRLQVDMDELEEKNRSIQAALDSAYKELTDLHKANAAKDSEAQ
                     EAALSREMKAKEELSAALEKAQEEARQQQETLAIQVGDLRLALQRTEQAAARKEDYLR
                     HEIGELQQRLQEAENRNQELSQSVSSTTRPLLRQIENLQATLGSQTSSWEKLEKNLSD
                     RLGESQTLLAAAVERERAATEELLANKIQMSSMESQNSLLRQENSRFQAQLESEKNRL
                     CKLEDENNRYQVELENLKDEYVRTLEETRKEKTLLNSQLEMERMKVEQERKKAIFTQE
                     TIKEKERKPFSVSSTPTMSRSSSISGVDMAGLQTSFLSQDESHDHSFGPMPISANGSN
                     LYDAVRMGAGSSIIENLQSQLKLREGEITHLQLEIGNLEKTRSIMAEELVKLTNQNDE
                     LEEKVKEIPKLRTQLRDLDQRYNTILQMYGEKAEEAEELRLDLEDVKNMYKTQIDELL
                     RQSLS"
     exon            390..1594
                     /gene="TMF1"
                     /gene_synonym="ARA160; TMF"
                     /inference="alignment:Splign:2.1.0"
     exon            1595..1698
                     /gene="TMF1"
                     /gene_synonym="ARA160; TMF"
                     /inference="alignment:Splign:2.1.0"
     exon            1699..1825
                     /gene="TMF1"
                     /gene_synonym="ARA160; TMF"
                     /inference="alignment:Splign:2.1.0"
     exon            1826..1931
                     /gene="TMF1"
                     /gene_synonym="ARA160; TMF"
                     /inference="alignment:Splign:2.1.0"
     exon            1932..2074
                     /gene="TMF1"
                     /gene_synonym="ARA160; TMF"
                     /inference="alignment:Splign:2.1.0"
     exon            2075..2241
                     /gene="TMF1"
                     /gene_synonym="ARA160; TMF"
                     /inference="alignment:Splign:2.1.0"
     exon            2242..2398
                     /gene="TMF1"
                     /gene_synonym="ARA160; TMF"
                     /inference="alignment:Splign:2.1.0"
     exon            2399..2491
                     /gene="TMF1"
                     /gene_synonym="ARA160; TMF"
                     /inference="alignment:Splign:2.1.0"
     exon            2492..2648
                     /gene="TMF1"
                     /gene_synonym="ARA160; TMF"
                     /inference="alignment:Splign:2.1.0"
     exon            2649..2841
                     /gene="TMF1"
                     /gene_synonym="ARA160; TMF"
                     /inference="alignment:Splign:2.1.0"
     exon            2842..2911
                     /gene="TMF1"
                     /gene_synonym="ARA160; TMF"
                     /inference="alignment:Splign:2.1.0"
     exon            2912..3004
                     /gene="TMF1"
                     /gene_synonym="ARA160; TMF"
                     /inference="alignment:Splign:2.1.0"
     exon            3005..3106
                     /gene="TMF1"
                     /gene_synonym="ARA160; TMF"
                     /inference="alignment:Splign:2.1.0"
     exon            3107..3259
                     /gene="TMF1"
                     /gene_synonym="ARA160; TMF"
                     /inference="alignment:Splign:2.1.0"
     exon            3260..3385
                     /gene="TMF1"
                     /gene_synonym="ARA160; TMF"
                     /inference="alignment:Splign:2.1.0"
     exon            3386..6879
                     /gene="TMF1"
                     /gene_synonym="ARA160; TMF"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5560..5565
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TMF1"
                     /gene_synonym="ARA160; TMF"
                     /note="hexamer: AATAAA"
     polyA_site      5581
                     /gene="TMF1"
                     /gene_synonym="ARA160; TMF"
                     /note="major polyA site"
     regulatory      6858..6863
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TMF1"
                     /gene_synonym="ARA160; TMF"
                     /note="hexamer: AATAAA"
     polyA_site      6879
                     /gene="TMF1"
                     /gene_synonym="ARA160; TMF"
ORIGIN      
        1 gtagatttgg ttgctgtgta cgtggaagaa gcaagcgcat gcgcacatgg gcccccttcg
       61 tctcagctgt gcgggaacgg ccgagggtaa catcccgggc tcgcgggagg ctgtcggggt
      121 aatggccaca cgctgacaga accagccgag tggaaaaggg gagcgaagcc gttcctctgc
      181 acccttcccc aggcctgagg ccttcccgct tggtgctgcc gccgccactg ccggctgagg
      241 aggggcgatg agttggttca acgcctccca gctctccagc ttcgctaagc aggccctgtc
      301 ccaggcccag aagtctattg acagggttct ggacatccag gaagaggagc cgagcatctg
      361 ggccgagacc attccgtatg gagagccggg aataagttcc cctgtcagtg gaggatggga
      421 tacttcaacc tgggggttga aatcaaacac tgaacctcag agtccaccaa tagcctctcc
      481 taaagcaatc acaaagccag ttcggaggac tgtggtcgat gaatctgaaa atttcttcag
      541 tgcctttctc tcgccaactg atgtccagac cattcagaag agtccagtgg tatcaaaacc
      601 tccagcaaaa tcacaacgac cagaagaaga agtgaaaagc agcttacatg aatccttgca
      661 cattggccag tcaagaactc ctgaaacaac tgaatcacaa gtaaaagact cttctttgtg
      721 tgtttcaggg gaaactctgg cagcaggtac ttcatcacct aaaactgaag gcaagcacga
      781 agaaactgtt aataaagaat cggatatgaa ggtgccaact gtaagtttga aagtatctga
      841 aagtgtaatt gatgtgaaaa caactatgga aagtatatct aatacgtcta cgcagtctct
      901 cacagcagaa acaaaggaca tagctttgga acctaaggaa caaaaacatg aagacaggca
      961 gagcaataca ccttctcctc ctgttagtac cttttcatca ggtacttcta ccaccagtga
     1021 tattgaagtt ttagatcatg aaagtgtaat aagtgagagc tcagcgagct cgagacaaga
     1081 gactacagat tcaaaatcaa gtcttcactt gatgcagaca tcttttcagc ttctctctgc
     1141 atctgcttgt cctgaatata atcgtttaga tgatttccaa aaactcactg agagttgctg
     1201 ttcatctgat gcttttgaaa gaatagactc atttagtgta cagtcattag atagccggag
     1261 tgtaagtgaa atcaattcag atgatgaatt gtcaggcaag ggatatgctt tagtgcctat
     1321 tatagttaat tcttcaactc caaagtctaa aacagttgaa tctgctgaag gaaaatctga
     1381 agaagtaaat gaaacattag ttatacccac tgaggaagca gaaatggaag aaagtggacg
     1441 aagtgcaact cctgttaact gtgaacagcc tgatatcttg gtttcttcca caccaataaa
     1501 tgaaggacag actgtgttag acaaggtggc tgagcagtgt gaacctgctg aaagtcagcc
     1561 agaagcactt tctgagaagg aagatgtttg caagacagtt gaatttctga atgaaaagct
     1621 ggaaaaaagg gaggctcagt tattatctct tagtaaggaa aaagcacttc tagaagaagc
     1681 ttttgataac ctgaaagatg aaatgttcag agtgaaagaa gaaagcagta gcatttcttc
     1741 cttgaaagat gagtttactc aaagaattgc agaagcagaa aagaaagttc aactagcctg
     1801 caaagagaga gatgctgcta aaaaggaaat caaaaacata aaagaagaac ttgccactag
     1861 attaaatagt agtgaaactg cagacctttt gaaagagaaa gatgagcaga tccgagggtt
     1921 aatggaagaa ggagaaaaac tttcaaaaca gcagctgcac aattctaaca tcatcaagaa
     1981 attaagagct aaagacaagg agaatgaaaa tatggttgca aagctgaaca aaaaagttaa
     2041 agagctagaa gaggagttgc agcatttgaa acaggtcctt gatggcaaag aagaggttga
     2101 gaaacaacat agagaaaata ttaaaaaact aaattccatg gtagaacgcc aagagaaaga
     2161 tcttggccgt cttcaggtag acatggatga acttgaagaa aagaaccgaa gtattcaggc
     2221 tgccctggat agtgcataca aagaacttac tgatcttcac aaagccaatg ctgcaaagga
     2281 tagtgaggca caggaagctg ctctgagccg tgaaatgaaa gctaaagaag aactttctgc
     2341 agcattagag aaggcccaag aagaagcccg tcagcagcaa gaaacattag ccattcaagt
     2401 gggggacctt aggcttgcat tgcagcgtac agaacaagcg gctgccagaa aggaggatta
     2461 tttacgccat gagatcggtg aacttcagca gagactccag gaagcagaga atcgaaacca
     2521 ggaactgagt caaagtgttt catcaacaac aagaccattg cttcgacaaa tagaaaattt
     2581 gcaagcaacc ctgggatccc agacatcgtc gtgggagaaa ttagagaaga atctttctga
     2641 taggcttggt gaatcccaga ccttgctggc agcagcagtt gagagagaac gtgcagctac
     2701 agaagaactc cttgctaaca aaattcagat gtcttccatg gagtcacaga attctctttt
     2761 aagacaggaa aacagtagat ttcaagccca gctagaatca gagaaaaata ggctgtgtaa
     2821 actggaggat gagaacaata ggtaccaggt tgaattggaa aacctaaaag atgaatatgt
     2881 aagaacactt gaagagacga ggaaagaaaa gacattgttg aatagtcagt tagaaatgga
     2941 aagaatgaaa gttgaacaag aaaggaagaa agccattttt actcaagaaa caataaaaga
     3001 aaaggaacgc aagccatttt ctgtttctag cactcccacc atgtcacgct caagttcaat
     3061 aagtggtgtt gatatggcag gactacagac atcttttctg tctcaggatg agtctcatga
     3121 tcactcattt ggaccaatgc ctatatcagc aaatggaagc aatctttatg atgctgtaag
     3181 gatgggagca ggatcaagca taattgaaaa cctacagtct cagctaaagc taagggaagg
     3241 ggaaatcact catttacagc tagaaattgg caatctagaa aaaactcgat caataatggc
     3301 tgaagaacta gttaaattaa caaatcaaaa tgatgaactt gaagagaagg tgaaggagat
     3361 acccaaactt agaactcagc taagagattt ggatcaaagg tacaacacta ttctgcagat
     3421 gtatggagaa aaagcagaag aggcagaaga acttcgatta gatctcgaag atgtaaaaaa
     3481 tatgtacaaa actcaaatag atgaactttt aagacaaagt ctcagttaac ttgtgaaaat
     3541 tgaattccca tcaaactgaa tgtaagcatt taatatctaa acatttaatg tggacttcca
     3601 ataaattctt ttatagaatt agaaagtggg atttactgta gagtgtaaaa atttttttaa
     3661 aattgtttta cactatgtag taatatttac agttaaatta ttttgtgcaa tatttgaact
     3721 ttatttttga aactattctt taaagattta ttttttaaag cattcatttt ttttccttga
     3781 atagcacaga gatttattac tttatcctca tataaatatg gctagagaag aagaatggtg
     3841 ttcatatatg tattgtagat atacaactag ttgtatctat aatttgtaag tgtttatata
     3901 tatattaaga acatttgaag agtaatgtta acatactgaa actttgaaat ctttcacatt
     3961 taaaatttca acatatctta attactgctc atgaaaatgt acattaagtg ttaaagtaaa
     4021 aaattattaa atctgtggct attaaatttt aaactaattt ttttccttta aaagtaagag
     4081 tcacactgac actgtctgaa atttaaagag tgaatgattt aaacttaaaa aaaattttga
     4141 tctgaaaatt tatttcaccc agctttcaca attaagtctg tataaaatgt ggtacctttt
     4201 ggtacctatc cagagaaacc tgtacatatt caatgttatc tagatgtgat tggataatgg
     4261 agaaaattta tttataatga ttttgcaatg gcatcaataa catttaaatg attttgaaga
     4321 agtattattt tactacccta taaaatgaat cgaaaataat aaagttctta acataattta
     4381 ctctttaaaa attacctgtt catattttgt aaacccatat ttttagcaca ttaaaaatga
     4441 atgtttgata ttacagaata ttcataacaa aatggaagaa ttataggaat taacttgaat
     4501 ttggcatttt taattttgtg atttatcatt ttattttttc ttgaaatttc aaacacaagg
     4561 aaagcataga atagctttta aaagtagcta tgccttcttc caaatgttat tttattcaaa
     4621 aaggtaacca ggttgtgttt taaacctgtg aaatattgtg atgcatttta ttactgaaag
     4681 ttatttaact gcctttactt gcacataaaa actctcattt acggccaggt gctgtggctc
     4741 atgcctgtaa tcccagcact ttgggaggcc aaggcgggca tatcacctga tgtcaggagt
     4801 tcaagaccag catggccagc agtttggtga aaccccatct ctactaaaaa tacaaaaatt
     4861 agcctggcgt ggtggtgtgc gcctgtaatc ctagctactc gggaggctga ggcaggagca
     4921 ttgcttgaac ctgggaggtg gaggttacaa tgagccaaga ttgtgccact gcactccagc
     4981 atgggtgaca gagaaagact ccgtctcaaa aaaaaaaaaa caaactctta tttaattttt
     5041 agttaaaatt aaaacactag tacttcagaa tatagataca agtacaccat cttgaagaat
     5101 ttggagtttt tcagggcaat tcaaatgacc tcattttttg ttctttttgt attccagaca
     5161 gtgtttctgt cattggatct ctgattggta gtgttaataa atattctttc agtgtgagcc
     5221 agattcataa aattaatttt cttcatttta gtagtaaaaa gtagtctaat agctttttgt
     5281 cagcttgatt tttttgtgtg tgtaatattc aagggcagaa tgacaggaca gataagcaat
     5341 aagaaatgta tagaattaga aaatatagta gttccctctt acccatggga catacgttcc
     5401 aagaccccca gtgaacgtct gaaaccatgg atagtataga cacctctata cactgttttt
     5461 tcctatacat atatacctat gataaagttc tatttataaa tcagggacag caagagataa
     5521 acaataactg caaatagaac aattataaca gtgcactgta ataaaagtga tgtaaatgtg
     5581 atatgtctgt ctctttctct caaaatatct tattgtactg tactcacctg taatcagact
     5641 gtggttgacc gtgagtaacc gaaaccacag aaagcaaaat cgtggataag gggagactac
     5701 tctatatgaa acttaagtta caaaattctc tgaagcattt gaaactagac gttttggaat
     5761 tataaaatag tccctttaaa atatccacta gtagaaaaaa acttcatttg cagagaaaag
     5821 attgcaataa aactcattcc taaacttttc aattttataa aattaaacat tcttttttta
     5881 tccgtattaa caatttctag ttacatagtt tctagttaca tattaccata tattactctt
     5941 tatctacaaa taaatagctg atactcaaac tgatcatatt ttgattgtta aacacttgga
     6001 tctctcaata cttctgtaag ttaaagtgaa cttaaacagt ttcttgaaaa actccagtag
     6061 gtggcagaat acctattgaa tattcgttgc tatactttgc tgtttgtcat taaaacatct
     6121 ctacccatat tcttgcaaaa taatatttat attttaatgg ataggaaaat gatttgcaat
     6181 tagatgtttc cattcttgaa agaaaaaagc tgcaaataac attttcaaga atataaaaaa
     6241 atgagtaaac aaagggaagg ttgtttggtc atttatagac aattaagcac agactgtaga
     6301 tgtccttcca attcttggga ggctaaactg agtctaccat ttcttacatt tcttttacct
     6361 attttttgag aattgccagt tgtacagtgt ttagcatgtg gaatgtacca aatatatcta
     6421 tgttgtgact taagatattc taaatgtgga taacttctga cctaggaaac atgaagtttg
     6481 tagtgaagta agtgaaaaga atgttcagga aatttttttt ctccatctct tcagttggca
     6541 tttattgaga gttttatttg aatgcttatt aaaagtatat gatttataat atttagaaaa
     6601 tagaagaaaa aagaaaactg tagatgtttt atcttgtttt aatactgtat gtttagtacg
     6661 tatacattta tgttctagtg tatcaaaatt tttcattttc attaaagtga atccaatttt
     6721 ccatattcta ggtccatttt aaaccatgaa aactttaatc acatattttg taaagggctg
     6781 aaagtatgat ttaaactaca gattgatata ttttaattct aaatgaaagg taatgtaaat
     6841 aagcatggat ctgattgaat aaagatttta aaatagtaa
//
