LOCUS       NM_014738               5412 bp    mRNA    linear   PRI 06-OCT-2024
DEFINITION  Homo sapiens transmembrane protein 94 (TMEM94), transcript variant
            1, mRNA.
ACCESSION   NM_014738
VERSION     NM_014738.6
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5412)
  AUTHORS   Vishnu,N., Venkatesan,M., Madaris,T.R., Venkateswaran,M.K.,
            Stanley,K., Ramachandran,K., Chidambaram,A., Madesh,A.K., Yang,W.,
            Nair,J., Narkunan,M., Muthukumar,T., Karanam,V., Joseph,L.C.,
            Le,A., Osidele,A., Aslam,M.I., Morrow,J.P., Malicdan,M.C.,
            Stathopulos,P.B. and Madesh,M.
  TITLE     ERMA (TMEM94) is a P-type ATPase transporter for Mg2+ uptake in the
            endoplasmic reticulum
  JOURNAL   Mol Cell 84 (7), 1321-1337 (2024)
   PUBMED   38513662
  REMARK    GeneRIF: ERMA (TMEM94) is a P-type ATPase transporter for Mg[2+]
            uptake in the endoplasmic reticulum.
REFERENCE   2  (bases 1 to 5412)
  AUTHORS   Al-Hamed,M.H., Alsahan,N., Tulbah,M., Kurdi,W., Ali,W., Sayer,J.A.
            and Imtiaz,F.
  TITLE     Fetal Anomalies Associated with Novel Pathogenic Variants in TMEM94
  JOURNAL   Genes (Basel) 11 (9), 967 (2020)
   PUBMED   32825426
  REMARK    GeneRIF: Fetal Anomalies Associated with Novel Pathogenic Variants
            in TMEM94.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5412)
  AUTHORS   Stephen,J., Maddirevula,S., Nampoothiri,S., Burke,J.D., Herzog,M.,
            Shukla,A., Steindl,K., Eskin,A., Patil,S.J., Joset,P., Lee,H.,
            Garrett,L.J., Yokoyama,T., Balanda,N., Bodine,S.P., Tolman,N.J.,
            Zerfas,P.M., Zheng,A., Ramantani,G., Girisha,K.M., Rivas,C.,
            Suresh,P.V., Elkahloun,A., Alsaif,H.S., Wakil,S.M., Mahmoud,L.,
            Ali,R., Prochazkova,M., Kulkarni,A.B., Ben-Omran,T., Colak,D.,
            Morris,H.D., Rauch,A., Martinez-Agosto,J.A., Nelson,S.F.,
            Alkuraya,F.S., Gahl,W.A. and Malicdan,M.C.V.
  CONSRTM   Undiagnosed Diseases Network members
  TITLE     Bi-allelic TMEM94 Truncating Variants Are Associated with
            Neurodevelopmental Delay, Congenital Heart Defects, and Distinct
            Facial Dysmorphism
  JOURNAL   Am J Hum Genet 103 (6), 948-967 (2018)
   PUBMED   30526868
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DA317199.1, D83779.1, CN307648.1, DB545285.1 and H06743.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 22, 2018 this sequence version replaced NM_014738.5.
            
            ##Evidence-Data-START##
            Transcript exon combination :: D83779.1, BC045540.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000314256.12/ ENSP00000313885.7
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-20                DA317199.1         172-191
            21-2058             D83779.1           1-2038
            2059-2598           CN307648.1         101-640
            2599-5042           D83779.1           2579-5022
            5043-5338           DB545285.1         162-457
            5339-5412           H06743.1           9-82                c
FEATURES             Location/Qualifiers
     source          1..5412
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q25.1"
     gene            1..5412
                     /gene="TMEM94"
                     /gene_synonym="ERMA; IDDCDF; KIAA0195"
                     /note="transmembrane protein 94"
                     /db_xref="GeneID:9772"
                     /db_xref="HGNC:HGNC:28983"
                     /db_xref="MIM:618163"
     exon            1..117
                     /gene="TMEM94"
                     /gene_synonym="ERMA; IDDCDF; KIAA0195"
                     /inference="alignment:Splign:2.1.0"
     exon            118..247
                     /gene="TMEM94"
                     /gene_synonym="ERMA; IDDCDF; KIAA0195"
                     /inference="alignment:Splign:2.1.0"
     CDS             224..4294
                     /gene="TMEM94"
                     /gene_synonym="ERMA; IDDCDF; KIAA0195"
                     /EC_number="7.2.2.14"
                     /note="isoform 1 is encoded by transcript variant 1; ER
                     Mg2+ ATPase; endoplasmic reticulum magnesium ATPase;
                     endoplasmic reticulum magnesium-transporting P-type
                     ATPase"
                     /codon_start=1
                     /product="transmembrane protein 94 isoform 1"
                     /protein_id="NP_055553.3"
                     /db_xref="CCDS:CCDS32732.1"
                     /db_xref="GeneID:9772"
                     /db_xref="HGNC:HGNC:28983"
                     /db_xref="MIM:618163"
                     /translation="MDLKEKHLGEPPSALGLSTRKALSVLKEQLEAVLEGHLRERKKC
                     LTWKEVWRSSFLHHSNRCSCFHWPGASLMLLAVLLLLGCCGGQPAGSRGVGLVNASAL
                     FLLLLLNLVLIGRQDRLKRREVERRLRGIIDQIQDALRDGREIQWPSAMYPDLHMPFA
                     PSWSLHWAYRDGHLVNLPVSLLVEGDIIALRPGQESFASLRGIKDDEHIVLEPGDLFP
                     PFSPPPSPRGEVERGPQSPQQHRLFRVLETPVIDNIRWCLDMALSRPVTALDNERFTV
                     QSVMLHYAVPVVLAGFLITNALRFIFSAPGVTSWQYTLLQLQVNGVLPILPLLFPVLW
                     VLATACGEARVLAQMSKASPSSLLAKFSEDTLSSYTEAVSSQEMLRCIWGHFLRVLGG
                     TSPTLSHSSSLLHSLGSVTVLCCVDKQGILSWPNPSPETVLFFSGKVEPPHSSHEDLT
                     DGLSTRSFCHPEPHERDALLAGSLNNTLHLSNEQERGDWPGEAPKPPEPYSHHKAHGR
                     SKHPSGSNVSFSRDTEGGEEEPSKTQPGMESDPYEAEDFVCDYHLEMLSLSQDQQNPS
                     CIQFDDSNWQLHLTSLKPLGLNVLLNLCDASVTERLCRFSDHLCNIALQESHSAVLPV
                     HVPWGLCELARLIGFTPGAKELFKQENHLALYRLPSAETMKETSLGRLSCVTKRRPPL
                     SHMISLFIKDTTTSTEQMLSHGTADVVLEACTDFWDGADIYPLSGSDRKKVLDFYQRA
                     CLSGYCSAFAYKPMNCALSSQLNGKCIELVQVPGQSSIFTMCELPSTIPIKQNARRSS
                     WSSDEGIGEVLEKEDCMQALSGQIFMGMVSSQYQARLDIVRLIDGLVNACIRFVYFSL
                     EDELKSKVFAEKMGLETGWNCHISLTPNGDMPGSEIPPSSPSHAGSLHDDLNQVSRDD
                     AEGLLLMEEEGHSDLISFQPTDSDIPSFLEDSNRAKLPRGIHQVRPHLQNIDNVPLLV
                     PLFTDCTPETMCEMIKIMQEYGEVTCCLGSSANLRNSCLFLQSDISIALDPLYPSRCS
                     WETFGYATSISMAQASDGLSPLQLSGQLNSLPCSLTFRQEETISIIRLIEQARHATYG
                     IRKCFLFLLQCQLTLVVIQFLSCLVQLPPLLSTTDILWLSCFCYPLLSISLLGKPPHS
                     SIMSMATGKNLQSIPKKTQHYFLLCFLLKFSLTISSCLICFGFTLQSFCDSSRDRNLT
                     NCSSVMLPSNDDRAPAWFEDFANGLLSAQKLTAALIVLHTVFISITHVHRTKPLWRKS
                     PLTNLWWAVTVPVVLLGQVVQTAVDLQLWTHRDSHVHFGLEDVPLLTWLLGCLSLVLV
                     VVTNEIVKLHEIRVRVRYQKRQKLQFETKLGMNSPF"
     exon            248..367
                     /gene="TMEM94"
                     /gene_synonym="ERMA; IDDCDF; KIAA0195"
                     /inference="alignment:Splign:2.1.0"
     exon            368..495
                     /gene="TMEM94"
                     /gene_synonym="ERMA; IDDCDF; KIAA0195"
                     /inference="alignment:Splign:2.1.0"
     exon            496..632
                     /gene="TMEM94"
                     /gene_synonym="ERMA; IDDCDF; KIAA0195"
                     /inference="alignment:Splign:2.1.0"
     exon            633..835
                     /gene="TMEM94"
                     /gene_synonym="ERMA; IDDCDF; KIAA0195"
                     /inference="alignment:Splign:2.1.0"
     exon            836..987
                     /gene="TMEM94"
                     /gene_synonym="ERMA; IDDCDF; KIAA0195"
                     /inference="alignment:Splign:2.1.0"
     exon            988..1090
                     /gene="TMEM94"
                     /gene_synonym="ERMA; IDDCDF; KIAA0195"
                     /inference="alignment:Splign:2.1.0"
     exon            1091..1177
                     /gene="TMEM94"
                     /gene_synonym="ERMA; IDDCDF; KIAA0195"
                     /inference="alignment:Splign:2.1.0"
     exon            1178..1294
                     /gene="TMEM94"
                     /gene_synonym="ERMA; IDDCDF; KIAA0195"
                     /inference="alignment:Splign:2.1.0"
     exon            1295..1351
                     /gene="TMEM94"
                     /gene_synonym="ERMA; IDDCDF; KIAA0195"
                     /inference="alignment:Splign:2.1.0"
     exon            1352..1456
                     /gene="TMEM94"
                     /gene_synonym="ERMA; IDDCDF; KIAA0195"
                     /inference="alignment:Splign:2.1.0"
     exon            1457..1609
                     /gene="TMEM94"
                     /gene_synonym="ERMA; IDDCDF; KIAA0195"
                     /inference="alignment:Splign:2.1.0"
     exon            1610..1819
                     /gene="TMEM94"
                     /gene_synonym="ERMA; IDDCDF; KIAA0195"
                     /inference="alignment:Splign:2.1.0"
     exon            1820..2135
                     /gene="TMEM94"
                     /gene_synonym="ERMA; IDDCDF; KIAA0195"
                     /inference="alignment:Splign:2.1.0"
     exon            2136..2309
                     /gene="TMEM94"
                     /gene_synonym="ERMA; IDDCDF; KIAA0195"
                     /inference="alignment:Splign:2.1.0"
     exon            2310..2412
                     /gene="TMEM94"
                     /gene_synonym="ERMA; IDDCDF; KIAA0195"
                     /inference="alignment:Splign:2.1.0"
     exon            2413..2630
                     /gene="TMEM94"
                     /gene_synonym="ERMA; IDDCDF; KIAA0195"
                     /inference="alignment:Splign:2.1.0"
     exon            2631..2812
                     /gene="TMEM94"
                     /gene_synonym="ERMA; IDDCDF; KIAA0195"
                     /inference="alignment:Splign:2.1.0"
     exon            2813..2951
                     /gene="TMEM94"
                     /gene_synonym="ERMA; IDDCDF; KIAA0195"
                     /inference="alignment:Splign:2.1.0"
     exon            2952..3067
                     /gene="TMEM94"
                     /gene_synonym="ERMA; IDDCDF; KIAA0195"
                     /inference="alignment:Splign:2.1.0"
     exon            3068..3167
                     /gene="TMEM94"
                     /gene_synonym="ERMA; IDDCDF; KIAA0195"
                     /inference="alignment:Splign:2.1.0"
     exon            3168..3276
                     /gene="TMEM94"
                     /gene_synonym="ERMA; IDDCDF; KIAA0195"
                     /inference="alignment:Splign:2.1.0"
     exon            3277..3466
                     /gene="TMEM94"
                     /gene_synonym="ERMA; IDDCDF; KIAA0195"
                     /inference="alignment:Splign:2.1.0"
     exon            3467..3544
                     /gene="TMEM94"
                     /gene_synonym="ERMA; IDDCDF; KIAA0195"
                     /inference="alignment:Splign:2.1.0"
     exon            3545..3630
                     /gene="TMEM94"
                     /gene_synonym="ERMA; IDDCDF; KIAA0195"
                     /inference="alignment:Splign:2.1.0"
     exon            3631..3712
                     /gene="TMEM94"
                     /gene_synonym="ERMA; IDDCDF; KIAA0195"
                     /inference="alignment:Splign:2.1.0"
     exon            3713..3861
                     /gene="TMEM94"
                     /gene_synonym="ERMA; IDDCDF; KIAA0195"
                     /inference="alignment:Splign:2.1.0"
     exon            3862..3956
                     /gene="TMEM94"
                     /gene_synonym="ERMA; IDDCDF; KIAA0195"
                     /inference="alignment:Splign:2.1.0"
     exon            3957..4050
                     /gene="TMEM94"
                     /gene_synonym="ERMA; IDDCDF; KIAA0195"
                     /inference="alignment:Splign:2.1.0"
     exon            4051..4221
                     /gene="TMEM94"
                     /gene_synonym="ERMA; IDDCDF; KIAA0195"
                     /inference="alignment:Splign:2.1.0"
     exon            4222..5412
                     /gene="TMEM94"
                     /gene_synonym="ERMA; IDDCDF; KIAA0195"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5023..5028
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TMEM94"
                     /gene_synonym="ERMA; IDDCDF; KIAA0195"
                     /note="hexamer: ATTAAA"
     polyA_site      5048
                     /gene="TMEM94"
                     /gene_synonym="ERMA; IDDCDF; KIAA0195"
                     /note="major polyA site"
     regulatory      5391..5396
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TMEM94"
                     /gene_synonym="ERMA; IDDCDF; KIAA0195"
                     /note="hexamer: AATAAA"
     polyA_site      5412
                     /gene="TMEM94"
                     /gene_synonym="ERMA; IDDCDF; KIAA0195"
ORIGIN      
        1 ccccttagag ttgccagtaa cggacatggc tgcggccccc ggaggagggg acgtgaagtg
       61 aggagggggt tgggagggga gaggacgcgg gcgaggaaga ccagccccgg ggccccgatg
      121 ttgtgactgt gacagactca ctggggtttg tacatgctgg ggaggagcct tcctttcagg
      181 ggtgaccaca ttcatctggg catgcctgca gtactcttgg cccatggacc tgaaggagaa
      241 gcacctgggc gagcctccct cagccctggg cctgtccacg cggaaggccc tcagcgtcct
      301 gaaggagcag ctggaggcag tgctggaagg acatctcagg gagcggaaga agtgtctgac
      361 gtggaaggag gtgtggagaa gcagcttcct ccaccacagt aaccgctgct cctgcttcca
      421 ctggccgggg gcctcactca tgctactggc cgtgctgctg ctgctgggct gctgcggggg
      481 acagccagcc gggagccgtg gggtggggct ggtgaatgcc tcggccttgt tcctgttact
      541 gcttctcaac cttgtgctca tcgggcggca agaccggctg aagcgtcggg aggtagagcg
      601 gaggctgcga gggatcattg accaaatcca agatgccctc agggatggca gggagatcca
      661 gtggcccagt gccatgtatc cagacctcca catgcctttt gcgccatcct ggtccttgca
      721 ctgggcctac agagacggac acctggtcaa cctgccagtc agcctgctgg ttgaaggaga
      781 catcatagct ttgaggcctg gccaggaatc gtttgcttct ctgaggggga tcaaggatga
      841 cgagcacatc gtcctggagc cgggagacct cttccccccc ttctcccctc caccctcacc
      901 ccggggagaa gtggagagag ggccacagag cccccagcag caccggcttt tccgtgtcct
      961 tgagacccct gtgattgaca acatcagatg gtgcctggac atggccctgt cccgaccagt
     1021 cactgccctg gacaatgagc ggttcacagt gcagtcggtg atgctacact atgctgtgcc
     1081 cgtggtcctg gccggcttcc tcatcaccaa tgccctgcgc ttcatcttca gtgccccggg
     1141 ggtcacttcc tggcagtaca ccctcctcca gctccaggtg aatggcgtcc tgcccatcct
     1201 ccccctgctc tttccagtcc tctgggttct ggcaactgcc tgtggagagg cccgtgtcct
     1261 ggcccagatg agcaaggcct cacccagctc cctgctggct aagttctcag aggatactct
     1321 cagcagctat acggaggctg tctcctctca ggaaatgctg cgctgcattt ggggccactt
     1381 cctgagggtg ctcgggggga catcgccaac gctgagccac agttccagcc tgctgcacag
     1441 cctgggctct gtcacggtcc tgtgctgtgt ggacaaacag gggatcctgt catggccaaa
     1501 tcccagccca gagactgtac tgttcttcag cgggaaggtg gagccccctc acagcagcca
     1561 tgaggacctc accgatggcc tatccacccg ctccttctgc catcccgagc cccatgaacg
     1621 agacgccctc ctggctggct ccctgaacaa caccctgcac ctttccaatg agcaggagcg
     1681 tggcgactgg cctggcgagg ctcccaagcc ccccgagccc tattcacacc acaaagcgca
     1741 tggccgcagc aaacacccat ctggctccaa cgtgagcttc agcagggaca ccgagggtgg
     1801 tgaagaagag cccagcaaga cccagcctgg gatggagagc gacccctacg aagcagagga
     1861 ctttgtgtgt gactaccacc tggagatgct gagcctgtcc caggaccagc agaacccctc
     1921 ctgcatccag tttgatgact ccaactggca gctgcacctc acctccctca aacccctggg
     1981 cctcaatgtg ctgctgaacc tgtgtgatgc cagcgtcacc gagcgcctgt gccgattctc
     2041 cgaccacctg tgcaacatcg ccctgcaaga gagccacagc gccgtgctgc ccgtccatgt
     2101 gccctggggc ctctgcgagc ttgcccgcct cattggcttc actcctgggg ccaaggagct
     2161 tttcaagcag gagaaccatc tggcgctgta ccgcctcccc agtgccgaga caatgaagga
     2221 gacatcgctg gggcggctct cctgtgtcac caagcggcgg cctcccctca gccacatgat
     2281 cagcctcttc attaaagaca ccaccaccag cacagagcag atgctgtccc atggcaccgc
     2341 tgatgtggtc ttagaggcct gcacagactt ctgggacgga gctgacatct accctctctc
     2401 gggatctgac agaaagaaag tgctggactt ctaccagcga gcctgcctgt ctgggtattg
     2461 ctctgccttc gcctacaagc ccatgaactg cgccctgtcc tctcagctca atggcaagtg
     2521 catcgagctg gtacaggtgc ccggccaaag cagcatcttc accatgtgcg agctgcccag
     2581 caccatcccc atcaagcaga acgcccgccg cagcagctgg agctctgacg aagggatcgg
     2641 ggaggtgctg gagaaggaag actgcatgca ggccctgagc ggccagatct tcatgggcat
     2701 ggtgtcctcc cagtaccagg cccggctgga catcgtgcgc ctcattgatg ggcttgtcaa
     2761 cgcctgcatc cgctttgtct acttctcttt ggaggatgag ctcaaaagca aggtgtttgc
     2821 agaaaaaatg ggcctggaga caggctggaa ctgccacatc tccctcacac ccaatggtga
     2881 catgcctggc tccgagatcc ccccctccag ccccagccac gcaggctccc tgcatgatga
     2941 cctgaatcag gtgtcccgag atgatgcaga agggctcctc ctcatggagg aggagggcca
     3001 ctcggacctc atcagcttcc agcctacgga cagcgacatc cccagcttcc tggaggactc
     3061 caaccgggcc aagctgcccc ggggtatcca ccaagtgcgg ccccacctgc agaacattga
     3121 caacgtgccc ctgctagtgc cccttttcac cgactgcacc ccagagacca tgtgtgagat
     3181 gataaagatc atgcaagagt acggggaggt gacctgctgc ctgggcagct ctgccaacct
     3241 gcggaacagc tgcctcttcc tccagagcga catcagcatt gccctggatc ccctgtaccc
     3301 atcccgttgc tcctgggaga cctttggcta cgccaccagc atcagcatgg cccaggcctc
     3361 ggatggcctt tctcccctgc agctgtcagg gcagctcaac agcctgccct gttccctgac
     3421 ctttcgccag gaggagacca tcagcatcat ccggcttatc gaacaggctc ggcatgccac
     3481 ctatggcatc cgtaagtgct tcctcttcct gctgcagtgc cagctgactc ttgtggtcat
     3541 ccagttcctt tcttgcctgg tccagctgcc gccactcctg agtaccaccg acatcctgtg
     3601 gctgtcctgc ttttgctacc ctctgctcag catctctctg ctggggaagc ccccccatag
     3661 ctccatcatg tctatggcaa cggggaaaaa cctccagtcc attcccaaga agacccagca
     3721 ctacttcctg ctctgcttcc tgctcaagtt cagcctcacc atcagctcct gcctcatctg
     3781 ctttggcttc acactgcaga gcttctgtga cagctcccgg gaccgcaacc tcaccaactg
     3841 ctcctccgtc atgctgccca gcaacgacga cagggctcca gcctggtttg aggactttgc
     3901 caatggactg ctgtcggctc agaagctcac ggccgccctg attgtcctgc acactgtctt
     3961 catttccatc acccatgtgc atcgcaccaa gcccctgtgg agaaagagcc ccttgaccaa
     4021 cctctggtgg gccgtgacag tgcctgtggt gctgctgggt caggtggtcc agacggctgt
     4081 ggacctgcag ctgtggacac acagggacag ccacgtccac tttggcctgg aggacgtgcc
     4141 cctgctgaca tggctcctgg gctgcctgtc cctggtcctt gtggtggtga ccaatgagat
     4201 cgtgaagcta catgagattc gggtccgagt ccgctaccag aagcgacaga agctgcagtt
     4261 tgaaactaag ctgggcatga actctccctt ctgagccact ggctgtggtg gctgtagttg
     4321 cccccgtccc tggggctaaa gccagaccca tttctgaaca ggggagtttg tatcatgaat
     4381 gtttccaggt ttgctcctgc acccgtggca ctggaaaccc agctccccgt gtcagacccc
     4441 gctgtcttcc tgagccctgg ggctcactgt ggaggagctg acggcctggg cccttggcca
     4501 gtcctggctc ttccctgggc ctcaccaggg acactcttga atgtatggcc tcaggcgctc
     4561 cctagagggg ccctaaaccc cctcacctgt gagctacccc ctttagggat cccttgcccc
     4621 cttggagatc ccttgccccc cagtgcctct gctcgtgggt ccctggacac ggccttgaag
     4681 ccaaccttct ttggaggagc aacagcagca gccttggccg acgcgtccaa ctcccaaggc
     4741 tgccgtggag ggcagggggg tggtgcttgc ctggatgtgg ccccgagtgc ctcccctccc
     4801 tccctctgtg ggggagtctc ccgcctgaac ctgaagatgg agcagggccc ccgcttcgcc
     4861 ctggagcctc ttcctgtgcc tggctcaagc tggctgcctg tcagtcttgg ggaatctggc
     4921 ccaggtctcc tcagcctctg ccccagttct gggagaagtt tctactggtg tatatttttt
     4981 actggaaatg agccttttag gaatgaatgt agactggttt gtattaaaat gtgtcaattg
     5041 ctaagaaata cctgtggctg gtctgtaagg ccactccagg gtctgcccac ccccggcggt
     5101 ggctggcaaa gggaggccta aaccttcctc catctacgcg ggtgggtccc tcaggtctgg
     5161 ctcaggcgag acccctaggg tcaggggtcc ccatgtcaca gaggcaaaca cacagcccag
     5221 tcacgtggaa tggtgttttc attggtgtta gttgggggaa gaggttaatg gttacagagc
     5281 cagggcctgg gccaatgggg tcaggctctc cctgccctca ggtgggcagt cggggctcct
     5341 gctgtggtcc gaagcccctc ccccattgtg tcctctcagg cagttgatag aataaattcc
     5401 atttaaaata ta
//
