LOCUS       NM_001146685            3217 bp    mRNA    linear   PRI 11-JUN-2024
DEFINITION  Homo sapiens transmembrane protein 88B (TMEM88B), mRNA.
ACCESSION   NM_001146685 XM_927219
VERSION     NM_001146685.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3217)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 3217)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16899-16903 (2002)
   PUBMED   12477932
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL391244.11.
            
            On Sep 28, 2020 this sequence version replaced NM_001146685.1.
            
            Sequence Note:.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DN831326.1, DN831325.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2145743, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000378821.4/ ENSP00000455099.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-515               AL391244.11        30687-31201         c
            516-3217            AL391244.11        26817-29518         c
FEATURES             Location/Qualifiers
     source          1..3217
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p36.33"
     gene            1..3217
                     /gene="TMEM88B"
                     /note="transmembrane protein 88B"
                     /db_xref="GeneID:643965"
                     /db_xref="HGNC:HGNC:37099"
     exon            1..515
                     /gene="TMEM88B"
                     /inference="alignment:Splign:2.1.0"
     exon            516..3217
                     /gene="TMEM88B"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3190..3195
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TMEM88B"
                     /note="hexamer: ATTAAA"
     polyA_site      3217
                     /gene="TMEM88B"
                     /note="major polyA site"
ORIGIN      
        1 agagcaccag gagctggctg gggctggaga ctggcgctgc tggagctgca gctgcctggc
       61 agaggggaaa ctgaggtggg ggtgtggctc tgggacagac atcagggcag gacctcccta
      121 gccagggtcc acggtctggc tgggggatgt ggactggctg caacgtgggg cggggttaaa
      181 ggtcttccag ggcagccctg gagagcacca ctctgcattg agcaccgccc gggccacagg
      241 cctgcagtgg caggagcatg agtgagcagg ggagggagac ggaggaggag gaggggggag
      301 gtggtgcttc cgacacagcg cccatgctgc cccggggacc tcccgaccac caggcctcag
      361 ccctgacgtg cccagggtgg tcggggcccc cgctgctgcc cggccggctg ctggccgggc
      421 tcctgctgca cctcctgctg cccgccgcag ccttcctgct ggtgctcctg cccgcggccg
      481 ccgtcgtcta cctgggattc ctgtgccact cgagggtcca ccccgctccg ggtccccggt
      541 gccgcgcgct gttctcagac cgcggctccg cggcgctcat cgtgttcggg cttctctcgc
      601 tgccgccgct gctggtgctc gcctcggccg tccgcgcccg cctagcccgg cgcctccgcc
      661 cgctgctgcc tccgcccgct gggacccccg gaccccgccg ccccccgggg cgccccgacg
      721 aggacgagca actctgcgcc tgggtgtgac ccggcggccg ctgcgaaacc ccgggaggcc
      781 tccgagctcg cgcgcgaccc catcgcgtgg cccggcccgg aaaactgagg gtcgcccccg
      841 ctgccccttc ctggctgggc gcgcagcgct cccggcttac gaccccggcc tcccccgccc
      901 gcagccccgc ccccgccacg gagggcaggg gaggggaaga gaggggaggg gaggggaaga
      961 gaggggaggg gagggggaga gaggggaggg gaggggaggg gaagagggga ggggagggga
     1021 agagagggga ggggagggga agagagggga ggggagggga agagagggga ggggagggga
     1081 agaggggagg ggaggggagg ggaggcaaag agaggggagg tgagggaaag agaggagagg
     1141 ggaggggaag agaggggagg gaagggcagg gcagggcaga gcccggcagg cagccctcag
     1201 aggaggggcg caggccccag cccaaggcct cccgcgcctg cccaggtccc ggcctccatc
     1261 gtccagggct ctggggctcc caggggagac acccacgctc ggccaagccc agggttccag
     1321 aagcccaggg gtggcggcag ccgggctcag cctatggcca ggctcgcatt cagacatgcg
     1381 ccagcctcgg tcggctctct ccgggagaca ctaagatctc ctcactgact ttggtgttcc
     1441 ttggtctcac cagcgcgtcc tagctgtgcc gagctcacac ccaccctgtt tggtgtaagc
     1501 cacaggtcca caacgttcat cagctctgga aatccctcaa caattgtgtc cagtttcacc
     1561 acgaattcct tctccatatc ctcaccattt tcttttaccc cctcatcaaa ttactccctt
     1621 ccgtctaatc tgctgattaa ctcattcatt ttatcttaaa ttattatgtt aacatatcca
     1681 ggccaggcac ggtggctcac gcctgtaatc ccagcacttt gggaagccga ggagggcgga
     1741 tcaccagctc aggagatcca gatcatcctg gctaacacgg tgaaaccccg tctctactaa
     1801 aaaatacaga aattagctgg gcttggtggc gggcacctgt agtaccagct actcgggagg
     1861 ctgaggcagg agaatggcgt gaacctggga ggcaaagctt gcagtgagcc aagatcacgc
     1921 cactgcactc tagcttgggc gaaagagcga ggctccgtct caaaaaaaaa aaaaaaaaaa
     1981 attagctggg cgtggtggtg ggcacctata acctcagcta cttgggaggc tgaggcagga
     2041 ggatcgcttg aacccaggag gcagagattg cagtgagccg aaatcatgcc attgcactcc
     2101 agcctggaca acaagagcaa gactccatct taaaaacaaa caaaaaaaca acaaaaaaaa
     2161 ttagctggcc atggtggtgc acacctgtag tcccagctac tcaggaggct gaggcacaag
     2221 aatcatttga acactggagg cagaggttgg agtgagctga gagggtgcca ctgcactcca
     2281 gcctgggtga caaagtgaaa ctccatctca aaaaaaaaaa aaggttagca tatctaaaag
     2341 ttacatctga ttgtgtttta gatttgtctg atttttttta tggtctcttg atacatgctt
     2401 gctttttaga ttacagtttc cacttcttaa acatatttca tatatagtta ttttatattc
     2461 tgtactaaat aattccagtg tcctagtctt tgggggtcta aatctgtgac tggtgtttct
     2521 gccgattctc atcagtagca tggtgtttct ctgaacgttt ggttgtttaa ttgtcagctg
     2581 ttatcggaga caattctgag gtccaacttg gggatgcttc cctccagaga ctattcccct
     2641 tttccaggcg agaccaccct cggccccctc agtgaccctt gagacccctg gtttaagcag
     2701 cccctaggca gagaaacata cttgttccct ggccgcaggc tggctctctg tccctgtgtg
     2761 tgtccaggga gttatctgct ttcccaacca cttcccttca tcatccaggc ctccacacta
     2821 ctctgtctgt ttgtttactt agagacagag tcttgctctg ccgcccagtc tgagtgcagt
     2881 ggtgagctcc tagctctctg cagcctcgcc ctcccaggct caagtgatcc tcctgcctca
     2941 gcctcccaag tagctgtgac tagagtgcac caccacaccc agctaatttt aaattttttt
     3001 gtagagacgg ggtctcatca tgttgcccag gctggtctcg aactcctagg cacaagcaat
     3061 cctctcgcct cagcctccta aagtgttggg attacaggca tgagccaccc cacctggcct
     3121 tatttatttt tgctgtttaa ttttggggga gactcggaga tatttacttt cttggaaaca
     3181 caacagtcta ttaaaaatgt acgctcatag taattca
//
